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The map label for this gene is ygbD [C]

Identifier: 125624074

GI number: 125624074

Start: 1220371

End: 1222032

Strand: Direct

Name: ygbD [C]

Synonym: llmg_1249

Alternate gene names: 125624074

Gene position: 1220371-1222032 (Clockwise)

Preceding gene: 125624073

Following gene: 125624075

Centisome position: 48.25

GC content: 36.46

Gene sequence:

>1662_bases
ATGAAAATTATTATAATTGGTTCTGTAGCTTCAGGAACAAGTGTTGCTGCTAAGGCACGTAGAAATACAGAGAGTGCAGA
GATAACTCTTTATGATAAGGACACTGATATTTCTTACGCAGTATGTGGTATTCCATATGCTATTGGTGGGGAAATTGGTG
ATTTTGATGAGTTAACTCCTCGCGATGCTCGATGGTTTAAAAAACGTTACAATGTTGATATTCATACTTCTCATGAAGTT
TTAGATATTAATCATTCAACAAAATCTCTCAAAGTTAAGAACCTTTTGACTGGTGAAATATTTGATGATTCTTATGATAT
CCTTGTTTTTGCAACTGGAGCAACTTACCATAGACCTGAAGTTTTTCAAGGTAAATCATTCGATAATGTATTTCAAGTAA
GAAATATTAATAGTGGTAAAAACATTAAATCTTTCTTGGATGATAAAAAACCAAAAACAGCAATTGTTGTAGGAGCAGGT
TATATTGGTCTTGAAGTTGCCGAACAACTCAAAGAACGAGGACTTGATGTTACTGTGCTTCAACGTGGAAAACACCCAAT
GGCACACCTAGATTGGGATATGTCTATTCGCATTGAAGATGAAATGGAAAAGCAAAATGTTCATTTTCTATCTGAGGAAA
TAGTCACTGAAACAAGGGGAGAACAAACACTAAAAAGTGTCATAACAAGTAAAGGCAATGTCCTTAGCGCTGATTTGTAT
ATATTGGCTACTGGAGTTCGACCAAATACTCAACTCGCAGAATCAATCGGGGTGAAACTAGGTGAAACTGGAGCGATTGC
TACAGATACAACGATGGAAACTAATATTGAAGGTGTCTATGCCGTTGGGGATGTTGCAGAAAGTTTCCATGTGATTACTG
GGAAAGCGACATACCGCCCTTTGGCATCAACTGCAAATAAGATGGGGAGAATTGCAGGAGATGCAATGACTGGTGGACCT
CTTCGTTTTCAAGGTGTGCTTGGGACTGGAATCTTACGCTTCTTTGATTTAACCATTGCTCAAACAGGATTAACTGAAAA
AGAAGCGATCGAAGAAGGTTATGAAATAGCAGTATTATTCAATATTAAACCAGACAAACCTGATTACATGCACGGTAAAG
AAATGGTTATCAAAGCAGTCGCAGATAAGTTATCTCATCGAATTCTTGGAGTTCAAATTATTGGTCCTCAAGGCGTAGAT
AAAAGAATAGATGTTTTTGCCTCAACAATTACACTAGGGGTTACTGCAGAAGATTTGTTCCATATGGATTTAGCTTATGC
CCCACCATTTTCAACAACTAAAGACCCTGTCGCATATACAGGAATGGCACTAACCAATGCCTTAACTACTGCGCCATTAA
TAACGCCTCATGATTTGATGGAACTTCAAAAAAATAGTGCAGACATAACAATTATTGACACACGTGCAAAAGCAAGTTAT
GAAAAGAAACATATACCAAATGCAATAAATATTCCGTTGGCTGAACTTCGTGAAAAATCATCTATCCTTGATAAGGATAA
ATTGACAATCGTTTACTGCAATAAGGGAGTCACTGGTAATGCTTCTCAAAATGTCTTGAGGAATGAAGGATTTAGAGAAG
TATACAATTTATCAGGCGGAAATAAAAATTATCAAGAAATTGCAAAACAAGAAAAAAATTAG

Upstream 100 bases:

>100_bases
GAAGTAGAATGGATTAATAAAGTTGCCAAACTTTCTAATCAACACTATGCAGTAGCTAAATGGCAAGCTGACTTTGAAAA
ATAAAGGAAATGATTATCCT

Downstream 100 bases:

>100_bases
GGGAAAAACTCAATTATGAATCAAGTCACAAAGAAACTGTCGTTTTTCGACCGTTATCTGACACTTTGGATATTTGTAGC
AATGGGAATTGGAGTCGCTT

Product: hypothetical protein

Products: NA

Alternate protein names: CoA-disulfide reductase; CoADR [H]

Number of amino acids: Translated: 553; Mature: 553

Protein sequence:

>553_residues
MKIIIIGSVASGTSVAAKARRNTESAEITLYDKDTDISYAVCGIPYAIGGEIGDFDELTPRDARWFKKRYNVDIHTSHEV
LDINHSTKSLKVKNLLTGEIFDDSYDILVFATGATYHRPEVFQGKSFDNVFQVRNINSGKNIKSFLDDKKPKTAIVVGAG
YIGLEVAEQLKERGLDVTVLQRGKHPMAHLDWDMSIRIEDEMEKQNVHFLSEEIVTETRGEQTLKSVITSKGNVLSADLY
ILATGVRPNTQLAESIGVKLGETGAIATDTTMETNIEGVYAVGDVAESFHVITGKATYRPLASTANKMGRIAGDAMTGGP
LRFQGVLGTGILRFFDLTIAQTGLTEKEAIEEGYEIAVLFNIKPDKPDYMHGKEMVIKAVADKLSHRILGVQIIGPQGVD
KRIDVFASTITLGVTAEDLFHMDLAYAPPFSTTKDPVAYTGMALTNALTTAPLITPHDLMELQKNSADITIIDTRAKASY
EKKHIPNAINIPLAELREKSSILDKDKLTIVYCNKGVTGNASQNVLRNEGFREVYNLSGGNKNYQEIAKQEKN

Sequences:

>Translated_553_residues
MKIIIIGSVASGTSVAAKARRNTESAEITLYDKDTDISYAVCGIPYAIGGEIGDFDELTPRDARWFKKRYNVDIHTSHEV
LDINHSTKSLKVKNLLTGEIFDDSYDILVFATGATYHRPEVFQGKSFDNVFQVRNINSGKNIKSFLDDKKPKTAIVVGAG
YIGLEVAEQLKERGLDVTVLQRGKHPMAHLDWDMSIRIEDEMEKQNVHFLSEEIVTETRGEQTLKSVITSKGNVLSADLY
ILATGVRPNTQLAESIGVKLGETGAIATDTTMETNIEGVYAVGDVAESFHVITGKATYRPLASTANKMGRIAGDAMTGGP
LRFQGVLGTGILRFFDLTIAQTGLTEKEAIEEGYEIAVLFNIKPDKPDYMHGKEMVIKAVADKLSHRILGVQIIGPQGVD
KRIDVFASTITLGVTAEDLFHMDLAYAPPFSTTKDPVAYTGMALTNALTTAPLITPHDLMELQKNSADITIIDTRAKASY
EKKHIPNAINIPLAELREKSSILDKDKLTIVYCNKGVTGNASQNVLRNEGFREVYNLSGGNKNYQEIAKQEKN
>Mature_553_residues
MKIIIIGSVASGTSVAAKARRNTESAEITLYDKDTDISYAVCGIPYAIGGEIGDFDELTPRDARWFKKRYNVDIHTSHEV
LDINHSTKSLKVKNLLTGEIFDDSYDILVFATGATYHRPEVFQGKSFDNVFQVRNINSGKNIKSFLDDKKPKTAIVVGAG
YIGLEVAEQLKERGLDVTVLQRGKHPMAHLDWDMSIRIEDEMEKQNVHFLSEEIVTETRGEQTLKSVITSKGNVLSADLY
ILATGVRPNTQLAESIGVKLGETGAIATDTTMETNIEGVYAVGDVAESFHVITGKATYRPLASTANKMGRIAGDAMTGGP
LRFQGVLGTGILRFFDLTIAQTGLTEKEAIEEGYEIAVLFNIKPDKPDYMHGKEMVIKAVADKLSHRILGVQIIGPQGVD
KRIDVFASTITLGVTAEDLFHMDLAYAPPFSTTKDPVAYTGMALTNALTTAPLITPHDLMELQKNSADITIIDTRAKASY
EKKHIPNAINIPLAELREKSSILDKDKLTIVYCNKGVTGNASQNVLRNEGFREVYNLSGGNKNYQEIAKQEKN

Specific function: Unknown

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI21389617, Length=372, Percent_Identity=26.0752688172043, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI226437568, Length=372, Percent_Identity=26.0752688172043, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI65787454, Length=372, Percent_Identity=26.0752688172043, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI91199540, Length=294, Percent_Identity=24.8299319727891, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI50301238, Length=292, Percent_Identity=25.3424657534247, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI33519430, Length=287, Percent_Identity=26.4808362369338, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI33519428, Length=287, Percent_Identity=26.4808362369338, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI33519426, Length=287, Percent_Identity=26.4808362369338, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI148277071, Length=287, Percent_Identity=26.4808362369338, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI148277065, Length=287, Percent_Identity=26.4808362369338, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1789065, Length=288, Percent_Identity=25, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789915, Length=280, Percent_Identity=27.8571428571429, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17559934, Length=227, Percent_Identity=30.3964757709251, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI32565766, Length=371, Percent_Identity=24.7978436657682, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17557007, Length=283, Percent_Identity=27.5618374558304, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6325166, Length=287, Percent_Identity=27.1777003484321, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24639257, Length=341, Percent_Identity=25.8064516129032, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI281359715, Length=341, Percent_Identity=25.8064516129032, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI281359713, Length=341, Percent_Identity=25.8064516129032, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24639250, Length=341, Percent_Identity=25.8064516129032, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI18543267, Length=341, Percent_Identity=25.8064516129032, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24639252, Length=341, Percent_Identity=25.8064516129032, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24640551, Length=298, Percent_Identity=27.8523489932886, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24640553, Length=298, Percent_Identity=27.8523489932886, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24585130, Length=332, Percent_Identity=25.3012048192771, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24640549, Length=298, Percent_Identity=27.8523489932886, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017758
- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.8.1.14 [H]

Molecular weight: Translated: 60709; Mature: 60709

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIIIGSVASGTSVAAKARRNTESAEITLYDKDTDISYAVCGIPYAIGGEIGDFDELTP
CEEEEEECCCCCCHHHHHHHCCCCCEEEEEEECCCCCEEEEECCCEEECCCCCCCCCCCC
RDARWFKKRYNVDIHTSHEVLDINHSTKSLKVKNLLTGEIFDDSYDILVFATGATYHRPE
CHHHHHHHHCCEEEECCCEEEEECCCCCCEEEEHEEECEECCCCCCEEEEEECCCCCCCC
VFQGKSFDNVFQVRNINSGKNIKSFLDDKKPKTAIVVGAGYIGLEVAEQLKERGLDVTVL
CCCCCCCCCEEEEECCCCCCHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHCCCEEEEE
QRGKHPMAHLDWDMSIRIEDEMEKQNVHFLSEEIVTETRGEQTLKSVITSKGNVLSADLY
ECCCCCCEEECCCEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEE
ILATGVRPNTQLAESIGVKLGETGAIATDTTMETNIEGVYAVGDVAESFHVITGKATYRP
EEEECCCCCHHHHHHHCCEECCCCCEEECCCEECCCCEEEEECHHCCCEEEEECCCCCCH
LASTANKMGRIAGDAMTGGPLRFQGVLGTGILRFFDLTIAQTGLTEKEAIEEGYEIAVLF
HHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEEE
NIKPDKPDYMHGKEMVIKAVADKLSHRILGVQIIGPQGVDKRIDVFASTITLGVTAEDLF
EECCCCCCCCCHHHHHHHHHHHHHHCEEEEEEEECCCCCCHHHHHEEEEEEEECCHHHHH
HMDLAYAPPFSTTKDPVAYTGMALTNALTTAPLITPHDLMELQKNSADITIIDTRAKASY
HHHEEECCCCCCCCCCCEEECHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEECCCCCCH
EKKHIPNAINIPLAELREKSSILDKDKLTIVYCNKGVTGNASQNVLRNEGFREVYNLSGG
HHHHCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHCCCHHHHHHCCCC
NKNYQEIAKQEKN
CCCHHHHHHHCCC
>Mature Secondary Structure
MKIIIIGSVASGTSVAAKARRNTESAEITLYDKDTDISYAVCGIPYAIGGEIGDFDELTP
CEEEEEECCCCCCHHHHHHHCCCCCEEEEEEECCCCCEEEEECCCEEECCCCCCCCCCCC
RDARWFKKRYNVDIHTSHEVLDINHSTKSLKVKNLLTGEIFDDSYDILVFATGATYHRPE
CHHHHHHHHCCEEEECCCEEEEECCCCCCEEEEHEEECEECCCCCCEEEEEECCCCCCCC
VFQGKSFDNVFQVRNINSGKNIKSFLDDKKPKTAIVVGAGYIGLEVAEQLKERGLDVTVL
CCCCCCCCCEEEEECCCCCCHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHCCCEEEEE
QRGKHPMAHLDWDMSIRIEDEMEKQNVHFLSEEIVTETRGEQTLKSVITSKGNVLSADLY
ECCCCCCEEECCCEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEE
ILATGVRPNTQLAESIGVKLGETGAIATDTTMETNIEGVYAVGDVAESFHVITGKATYRP
EEEECCCCCHHHHHHHCCEECCCCCEEECCCEECCCCEEEEECHHCCCEEEEECCCCCCH
LASTANKMGRIAGDAMTGGPLRFQGVLGTGILRFFDLTIAQTGLTEKEAIEEGYEIAVLF
HHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEEE
NIKPDKPDYMHGKEMVIKAVADKLSHRILGVQIIGPQGVDKRIDVFASTITLGVTAEDLF
EECCCCCCCCCHHHHHHHHHHHHHHCEEEEEEEECCCCCCHHHHHEEEEEEEECCHHHHH
HMDLAYAPPFSTTKDPVAYTGMALTNALTTAPLITPHDLMELQKNSADITIIDTRAKASY
HHHEEECCCCCCCCCCCEEECHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEECCCCCCH
EKKHIPNAINIPLAELREKSSILDKDKLTIVYCNKGVTGNASQNVLRNEGFREVYNLSGG
HHHHCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHCCCHHHHHHCCCC
NKNYQEIAKQEKN
CCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA