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The map label for this gene is aroH [H]

Identifier: 125624053

GI number: 125624053

Start: 1198699

End: 1199721

Strand: Direct

Name: aroH [H]

Synonym: llmg_1227

Alternate gene names: 125624053

Gene position: 1198699-1199721 (Clockwise)

Preceding gene: 125624052

Following gene: 125624055

Centisome position: 47.39

GC content: 35.29

Gene sequence:

>1023_bases
ATGTCATTCAAAGAAATGAGTAAAAAGATTAACATCAGTGATGTAAAAGAGTTGAGCCACTTAAATAGTGAGCAACAAGA
AAAGAAAGATAAACGAGATAAAGAACTAGAAGCCATTATTAAAGGAGAAGATGAACGAATCTTGTTAGTTATTGGTCCTT
GTTCATCGGATAATGAAAGTGCTGTTTTGGAATATGCTCATCGATTATCAAAGCTTCAGAAGAAAGTAGAAGATAAAATA
TTTATTGTCATGCGTGTTTATACGGCTAAACCAAGAACAAATGGTGATGGATATAAAGGATTGATTCACGAACCAGATGC
AGACGGCCATACTGATTTAATTAATGGAATAAAAATGGTTCGGGACTTACATTATAAAGTCATTACTGAAACTGGTTTGA
CAACTGCTGATGAAATGCTCTACCCAGAAAATTTGCCACTTGTTGATGACTTGGTCAGTTATTACGCAGTTGGCGCTCGC
TCCGTTGAGAATCAACAACACCGTTTCGTTGCATCTGGTATTGATGCACCAACTGGAATGAAAAATCCTACATCAGGGAA
CTTAAAAGTGATGTTCAATGGAATTTATGCGGCTCAACAATCACAAGATTTTCTTTTTGGGAATGCTGAGGTAGAAACAT
CAGGAAATTCACTTGCTCATGCAATTCTTCGCGGTGGTCAAGATGAAAATGGCAAGAATCATCCAAATTACTACACGGAT
AACCTTCTGGAAAGTATTGAAATCTATGAAAAAATGGGATTAAAAAATCCATTTATCGTCATTGATACCAACCATGATAA
TTCTGGAAAAAAATATATGGAGCAAATCAGAATTGTCCGCCAAACTTTGGTAAATCGTAATTGGGATGAACAAATTCATA
AATATGTTAGAGGATTTATGATTGAATCATATCTTGAGGACGGGCGACAAGACCATCCAGATGTTTTCGGAAAATCAATT
ACCGATCCATGTTTAGGTTGGGATAAAACAGAACAAGTCATAAATGAAATTTACAATTCATAA

Upstream 100 bases:

>100_bases
ATTTGGAGGTAATGATAAAAAGAAAAATAGAAATATGTTGCAGGTAAGATCTTAGTTAAATAGATTTTACTTAGAAGATA
ACTTTAGAAAAGAGTAGAAA

Downstream 100 bases:

>100_bases
TAAAAGATAGTCAGCACAAACATGATGACTATCTTTTATTACATTAGCTTAGCAAAATAATTAATTACTACCAAAAGTAA
AAATACTTTTAAGATTGATA

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MSFKEMSKKINISDVKELSHLNSEQQEKKDKRDKELEAIIKGEDERILLVIGPCSSDNESAVLEYAHRLSKLQKKVEDKI
FIVMRVYTAKPRTNGDGYKGLIHEPDADGHTDLINGIKMVRDLHYKVITETGLTTADEMLYPENLPLVDDLVSYYAVGAR
SVENQQHRFVASGIDAPTGMKNPTSGNLKVMFNGIYAAQQSQDFLFGNAEVETSGNSLAHAILRGGQDENGKNHPNYYTD
NLLESIEIYEKMGLKNPFIVIDTNHDNSGKKYMEQIRIVRQTLVNRNWDEQIHKYVRGFMIESYLEDGRQDHPDVFGKSI
TDPCLGWDKTEQVINEIYNS

Sequences:

>Translated_340_residues
MSFKEMSKKINISDVKELSHLNSEQQEKKDKRDKELEAIIKGEDERILLVIGPCSSDNESAVLEYAHRLSKLQKKVEDKI
FIVMRVYTAKPRTNGDGYKGLIHEPDADGHTDLINGIKMVRDLHYKVITETGLTTADEMLYPENLPLVDDLVSYYAVGAR
SVENQQHRFVASGIDAPTGMKNPTSGNLKVMFNGIYAAQQSQDFLFGNAEVETSGNSLAHAILRGGQDENGKNHPNYYTD
NLLESIEIYEKMGLKNPFIVIDTNHDNSGKKYMEQIRIVRQTLVNRNWDEQIHKYVRGFMIESYLEDGRQDHPDVFGKSI
TDPCLGWDKTEQVINEIYNS
>Mature_339_residues
SFKEMSKKINISDVKELSHLNSEQQEKKDKRDKELEAIIKGEDERILLVIGPCSSDNESAVLEYAHRLSKLQKKVEDKIF
IVMRVYTAKPRTNGDGYKGLIHEPDADGHTDLINGIKMVRDLHYKVITETGLTTADEMLYPENLPLVDDLVSYYAVGARS
VENQQHRFVASGIDAPTGMKNPTSGNLKVMFNGIYAAQQSQDFLFGNAEVETSGNSLAHAILRGGQDENGKNHPNYYTDN
LLESIEIYEKMGLKNPFIVIDTNHDNSGKKYMEQIRIVRQTLVNRNWDEQIHKYVRGFMIESYLEDGRQDHPDVFGKSIT
DPCLGWDKTEQVINEIYNS

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787996, Length=317, Percent_Identity=36.5930599369085, Blast_Score=202, Evalue=2e-53,
Organism=Escherichia coli, GI1786969, Length=322, Percent_Identity=39.1304347826087, Blast_Score=201, Evalue=6e-53,
Organism=Escherichia coli, GI1788953, Length=331, Percent_Identity=37.7643504531722, Blast_Score=199, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6320240, Length=311, Percent_Identity=36.0128617363344, Blast_Score=178, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6319726, Length=325, Percent_Identity=35.6923076923077, Blast_Score=171, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 38678; Mature: 38547

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFKEMSKKINISDVKELSHLNSEQQEKKDKRDKELEAIIKGEDERILLVIGPCSSDNES
CCHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHH
AVLEYAHRLSKLQKKVEDKIFIVMRVYTAKPRTNGDGYKGLIHEPDADGHTDLINGIKMV
HHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
RDLHYKVITETGLTTADEMLYPENLPLVDDLVSYYAVGARSVENQQHRFVASGIDAPTGM
HHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
KNPTSGNLKVMFNGIYAAQQSQDFLFGNAEVETSGNSLAHAILRGGQDENGKNHPNYYTD
CCCCCCCEEEEEEEHHHHCCCCCEEECCCEEECCCHHHHHHHHHCCCCCCCCCCCCCHHH
NLLESIEIYEKMGLKNPFIVIDTNHDNSGKKYMEQIRIVRQTLVNRNWDEQIHKYVRGFM
HHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
IESYLEDGRQDHPDVFGKSITDPCLGWDKTEQVINEIYNS
HHHHHHCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SFKEMSKKINISDVKELSHLNSEQQEKKDKRDKELEAIIKGEDERILLVIGPCSSDNES
CHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHH
AVLEYAHRLSKLQKKVEDKIFIVMRVYTAKPRTNGDGYKGLIHEPDADGHTDLINGIKMV
HHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
RDLHYKVITETGLTTADEMLYPENLPLVDDLVSYYAVGARSVENQQHRFVASGIDAPTGM
HHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
KNPTSGNLKVMFNGIYAAQQSQDFLFGNAEVETSGNSLAHAILRGGQDENGKNHPNYYTD
CCCCCCCEEEEEEEHHHHCCCCCEEECCCEEECCCHHHHHHHHHCCCCCCCCCCCCCHHH
NLLESIEIYEKMGLKNPFIVIDTNHDNSGKKYMEQIRIVRQTLVNRNWDEQIHKYVRGFM
HHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
IESYLEDGRQDHPDVFGKSITDPCLGWDKTEQVINEIYNS
HHHHHHCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9422601 [H]