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The map label for this gene is cdd [H]

Identifier: 125623894

GI number: 125623894

Start: 1023030

End: 1023422

Strand: Direct

Name: cdd [H]

Synonym: llmg_1063

Alternate gene names: 125623894

Gene position: 1023030-1023422 (Clockwise)

Preceding gene: 125623893

Following gene: 125623895

Centisome position: 40.44

GC content: 39.69

Gene sequence:

>393_bases
ATGACAGCTACTAAAGAGATGATAGTGGCTGCTCGTGAGGCTGCAAGTCTAGCCTACGTCCCTTACTCACACTTTCCAGT
TGGAGCAGCTTTTCTAACAGCTGATGGTCAGGTTATTAAAGGCTGCAATATTGAAAATGCTAGTTTTGGTTTATCAAATT
GTGCTGAACGGACAGCTATTTTTAAAGCAATTTCAGAAGGTGTCAAAGATTTTGACGCACTCTATGTTTTTGGAGAAACA
GAAGAACCAATTAGCCCTTGTGGTGCTTGCCGGCAAGTACTTGCAGAATTTTGTCCAGCCGATATGCCGGTTTATCTTAT
CTCAAAAGATGATAAAGTAAAAGAAACGTCTGTCGAAGGACTTTTACCTTATTCTTTTAAAAGCCTTGATTAA

Upstream 100 bases:

>100_bases
GGTGTTCATAATCTTGAAGAAGCAAAAGCAATGATTGATGCTGGAGCAACTCGTCTTGGAGTTTCTGCTGGTGTCGCAAT
TATGGAAGGTCTTACCTCAA

Downstream 100 bases:

>100_bases
GTAAAAATGTAAAAGTTAAATATGCTATCTTTAGATAGCATATCAATTTGCAATCAAAGTAAGCGCTTCATATCTTGTCT
TAAATGTAAAGTAATAATGG

Product: Cdd protein

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 130; Mature: 129

Protein sequence:

>130_residues
MTATKEMIVAAREAASLAYVPYSHFPVGAAFLTADGQVIKGCNIENASFGLSNCAERTAIFKAISEGVKDFDALYVFGET
EEPISPCGACRQVLAEFCPADMPVYLISKDDKVKETSVEGLLPYSFKSLD

Sequences:

>Translated_130_residues
MTATKEMIVAAREAASLAYVPYSHFPVGAAFLTADGQVIKGCNIENASFGLSNCAERTAIFKAISEGVKDFDALYVFGET
EEPISPCGACRQVLAEFCPADMPVYLISKDDKVKETSVEGLLPYSFKSLD
>Mature_129_residues
TATKEMIVAAREAASLAYVPYSHFPVGAAFLTADGQVIKGCNIENASFGLSNCAERTAIFKAISEGVKDFDALYVFGETE
EPISPCGACRQVLAEFCPADMPVYLISKDDKVKETSVEGLLPYSFKSLD

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=127, Percent_Identity=51.9685039370079, Blast_Score=130, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17540514, Length=128, Percent_Identity=48.4375, Blast_Score=120, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17551074, Length=129, Percent_Identity=47.2868217054264, Blast_Score=105, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6323274, Length=120, Percent_Identity=37.5, Blast_Score=88, Evalue=4e-19,
Organism=Drosophila melanogaster, GI19920920, Length=142, Percent_Identity=44.3661971830986, Blast_Score=109, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24582741, Length=127, Percent_Identity=48.0314960629921, Blast_Score=107, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24582744, Length=141, Percent_Identity=41.1347517730496, Blast_Score=99, Evalue=8e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 14000; Mature: 13869

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATKEMIVAAREAASLAYVPYSHFPVGAAFLTADGQVIKGCNIENASFGLSNCAERTAI
CCCHHHHHHHHHHHCCEEECCCCCCCCCEEEEECCCCEEECCCCCCCCCCHHHHHHHHHH
FKAISEGVKDFDALYVFGETEEPISPCGACRQVLAEFCPADMPVYLISKDDKVKETSVEG
HHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHCCCC
LLPYSFKSLD
CCCCCCCCCC
>Mature Secondary Structure 
TATKEMIVAAREAASLAYVPYSHFPVGAAFLTADGQVIKGCNIENASFGLSNCAERTAI
CCHHHHHHHHHHHCCEEECCCCCCCCCEEEEECCCCEEECCCCCCCCCCHHHHHHHHHH
FKAISEGVKDFDALYVFGETEEPISPCGACRQVLAEFCPADMPVYLISKDDKVKETSVEG
HHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHCCCC
LLPYSFKSLD
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11739901 [H]