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The map label for this gene is trpB [H]

Identifier: 125623874

GI number: 125623874

Start: 1002258

End: 1003463

Strand: Direct

Name: trpB [H]

Synonym: llmg_1041

Alternate gene names: 125623874

Gene position: 1002258-1003463 (Clockwise)

Preceding gene: 125623873

Following gene: 125623875

Centisome position: 39.62

GC content: 41.87

Gene sequence:

>1206_bases
ATGACCTACAATCAACCCAATAACCAAGGATTTTATGGACAATTTGGTGGACAATTTGTCCCTGAAACTTTAATGACAGC
CGTAAAAGAATTAGAAGTAGCTTATGAAGACAGTAAAAAAGATCCAGTTTTTCAAGCTGAACTAAAAGAATTGCTTAAAG
ATTACGTTGGACGAGAAAACCCACTTTATTTTGCTAAACGCCTGACCGAATATGCTGGTGGTGCAAAAATTTATCTCAAA
CGCGAAGACCTTAATCACACCGGAGCTCACAAAATAAATAACGCCCTTGGCCAAGTCCTCCTTGCCAAAAAAATGGGAAA
AAACAAAGTCATTGCTGAGACAGGAGCGGGCCAACATGGAGTCGCAACGGCAACAGCGGCTGCCCTCTTTGGCATGGAAT
GTACCATATATATGGGTGAAGAAGATGTCAAAAGACAATCTCTTAATGTTTTTCGGATGGAATTGCTCGGTGCAAAAGTC
CATTCAGTTACTGATGGTTCGCGCGTGCTTAAAGATGCGGTAAATGCAGCACTTAGAGCATGGGTTGCTCAAGTTGAGGA
TACACATTATGTGATGGGTTCAGTTCTCGGACCTCACCCATTCCCACAAATTGTTCGTGATTATCAAGCCATCATTGGTC
AAGAAGCACGTGCACAATTCTTAGAAAAAGAAAATAAACTACCAGATGCTTTAGTGGCTTGTGTTGGGGGCGGTTCAAAC
TCGATGGGACTTTTCTACCCATTCGTTAATGACGAATCAGTAGAGATGTATGGTGTTGAAGCAGCTGGGCTTGGGATAGA
TACTCCACACCATGCAGCAACAATTACTAAAGGGCGTCCAGGGGTTTTACACGGCACGCTTATGGATGTTCTTCAAGATG
AAAATGGACAAATACTAGAAGCTTTCAGTATTTCTGCTGGTTTAGACTATCCAGGAATTGGACCTGAACATTCCTATTTC
AATGCGGTCGGCCGTGCAAAGTATGTTGATATTACTGATGAAGAAGCCCTTGAAGGTTTCAAAATCTTATCTCGCACAGA
AGGAATCATACCGGCCCTTGAAAGCTCTCACGCGATTGCCTATGCGGTCAAATTAGCTAAAGAATTAGGTTCAGAAAAAA
CAATGATTGTTTGCTTATCAGGTCGCGGCGATAAAGATGTTGTTCAAGTTAAAGAACGTCTTGAAGCAGAAAAAGAGGTG
AAATAA

Upstream 100 bases:

>100_bases
GGCAAGAAGAATGGCATGATTCAGTAAAATATGGAATTTTACGAGAAGAACAGTAAAAATAAAACAATTAAAATATAACA
TTTACAAAAAGGAGAAATAC

Downstream 100 bases:

>100_bases
TGAAAACTTTACAAGCAAAATTGAGCAATAAAAAAAATAATTTTGTTCCCTATATTATGGCAGGTGACCATGAAAGAGGA
TTAGAAGGGCTCAATGAAAC

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MTYNQPNNQGFYGQFGGQFVPETLMTAVKELEVAYEDSKKDPVFQAELKELLKDYVGRENPLYFAKRLTEYAGGAKIYLK
REDLNHTGAHKINNALGQVLLAKKMGKNKVIAETGAGQHGVATATAAALFGMECTIYMGEEDVKRQSLNVFRMELLGAKV
HSVTDGSRVLKDAVNAALRAWVAQVEDTHYVMGSVLGPHPFPQIVRDYQAIIGQEARAQFLEKENKLPDALVACVGGGSN
SMGLFYPFVNDESVEMYGVEAAGLGIDTPHHAATITKGRPGVLHGTLMDVLQDENGQILEAFSISAGLDYPGIGPEHSYF
NAVGRAKYVDITDEEALEGFKILSRTEGIIPALESSHAIAYAVKLAKELGSEKTMIVCLSGRGDKDVVQVKERLEAEKEV
K

Sequences:

>Translated_401_residues
MTYNQPNNQGFYGQFGGQFVPETLMTAVKELEVAYEDSKKDPVFQAELKELLKDYVGRENPLYFAKRLTEYAGGAKIYLK
REDLNHTGAHKINNALGQVLLAKKMGKNKVIAETGAGQHGVATATAAALFGMECTIYMGEEDVKRQSLNVFRMELLGAKV
HSVTDGSRVLKDAVNAALRAWVAQVEDTHYVMGSVLGPHPFPQIVRDYQAIIGQEARAQFLEKENKLPDALVACVGGGSN
SMGLFYPFVNDESVEMYGVEAAGLGIDTPHHAATITKGRPGVLHGTLMDVLQDENGQILEAFSISAGLDYPGIGPEHSYF
NAVGRAKYVDITDEEALEGFKILSRTEGIIPALESSHAIAYAVKLAKELGSEKTMIVCLSGRGDKDVVQVKERLEAEKEV
K
>Mature_400_residues
TYNQPNNQGFYGQFGGQFVPETLMTAVKELEVAYEDSKKDPVFQAELKELLKDYVGRENPLYFAKRLTEYAGGAKIYLKR
EDLNHTGAHKINNALGQVLLAKKMGKNKVIAETGAGQHGVATATAAALFGMECTIYMGEEDVKRQSLNVFRMELLGAKVH
SVTDGSRVLKDAVNAALRAWVAQVEDTHYVMGSVLGPHPFPQIVRDYQAIIGQEARAQFLEKENKLPDALVACVGGGSNS
MGLFYPFVNDESVEMYGVEAAGLGIDTPHHAATITKGRPGVLHGTLMDVLQDENGQILEAFSISAGLDYPGIGPEHSYFN
AVGRAKYVDITDEEALEGFKILSRTEGIIPALESSHAIAYAVKLAKELGSEKTMIVCLSGRGDKDVVQVKERLEAEKEVK

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=391, Percent_Identity=54.2199488491049, Blast_Score=444, Evalue=1e-126,
Organism=Saccharomyces cerevisiae, GI6321412, Length=384, Percent_Identity=57.8125, Blast_Score=474, Evalue=1e-134,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 43701; Mature: 43570

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYNQPNNQGFYGQFGGQFVPETLMTAVKELEVAYEDSKKDPVFQAELKELLKDYVGREN
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCC
PLYFAKRLTEYAGGAKIYLKREDLNHTGAHKINNALGQVLLAKKMGKNKVIAETGAGQHG
CHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCC
VATATAAALFGMECTIYMGEEDVKRQSLNVFRMELLGAKVHSVTDGSRVLKDAVNAALRA
HHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
WVAQVEDTHYVMGSVLGPHPFPQIVRDYQAIIGQEARAQFLEKENKLPDALVACVGGGSN
HHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHEEECCCCC
SMGLFYPFVNDESVEMYGVEAAGLGIDTPHHAATITKGRPGVLHGTLMDVLQDENGQILE
CCEEEEEECCCCCEEEEEEEECCCCCCCCCCCEEECCCCCCCHHHHHHHHHHCCCCCEEE
AFSISAGLDYPGIGPEHSYFNAVGRAKYVDITDEEALEGFKILSRTEGIIPALESSHAIA
EEEEECCCCCCCCCCCHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCHHH
YAVKLAKELGSEKTMIVCLSGRGDKDVVQVKERLEAEKEVK
HHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TYNQPNNQGFYGQFGGQFVPETLMTAVKELEVAYEDSKKDPVFQAELKELLKDYVGREN
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCC
PLYFAKRLTEYAGGAKIYLKREDLNHTGAHKINNALGQVLLAKKMGKNKVIAETGAGQHG
CHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCC
VATATAAALFGMECTIYMGEEDVKRQSLNVFRMELLGAKVHSVTDGSRVLKDAVNAALRA
HHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
WVAQVEDTHYVMGSVLGPHPFPQIVRDYQAIIGQEARAQFLEKENKLPDALVACVGGGSN
HHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHEEECCCCC
SMGLFYPFVNDESVEMYGVEAAGLGIDTPHHAATITKGRPGVLHGTLMDVLQDENGQILE
CCEEEEEECCCCCEEEEEEEECCCCCCCCCCCEEECCCCCCCHHHHHHHHHHCCCCCEEE
AFSISAGLDYPGIGPEHSYFNAVGRAKYVDITDEEALEGFKILSRTEGIIPALESSHAIA
EEEEECCCCCCCCCCCHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCHHH
YAVKLAKELGSEKTMIVCLSGRGDKDVVQVKERLEAEKEVK
HHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1400208; 11337471 [H]