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The map label for this gene is purN [H]

Identifier: 125623826

GI number: 125623826

Start: 952431

End: 952979

Strand: Direct

Name: purN [H]

Synonym: llmg_0988

Alternate gene names: 125623826

Gene position: 952431-952979 (Clockwise)

Preceding gene: 125623825

Following gene: 125623827

Centisome position: 37.65

GC content: 37.16

Gene sequence:

>549_bases
ATGAAAATTGCAGTATTTGCATCAGGAAATGGCTCTAACTTTCAAAGACTAGCTGAACAATTTCCTAAGGTAGTGAAGTT
TGTTTTTTCAGATCATCATGATGCTTATGTACTTGAACGTGCTGATAAATTAGGGGTAGCAAATGCAAGTTTGGAGTTAA
AAGAGTTTACTTCAAAAGTTGACTATGAGAAAGCTTTGGTGGAAATTTTAGAAGCACAAGAAATTGATTTAATTCTCTTG
GCTGGTTATATGAAAATCATCGGTTCGACGATGTTGGCAAGATATAAAGGAAAGATTATCAATGTGCATCCTTCTTTTCT
GCCTGATTTTGCTGGCTCTCCTCATGCGATTGAGGAGTCACATGAAGCAAAATATGGTCTAGGAATTACAATTCATTATG
TTGATGAGGGCGTGGATACTGGCGAAATTATCGCGCAAATCCCTGTGGCTTATCACGAAAGTTTGGAAGTTTATGAAGAG
AGAGTTCATGAAGCGGAACATGAGCTCTATCCAAAAGTTGTTCGTCAAATAATTCTTCATCAGCAATGA

Upstream 100 bases:

>100_bases
AAAGAGTTGAATGCTTTCGAGATTGGTCAAATGGTTAATCGACAAGAGGCACCAGTAGTTATTAAAAAATAATCTTTTTT
CATTAAGAATAGGGGATAGA

Downstream 100 bases:

>100_bases
TGAAGTTTTTTTATTTGGCCATTAATAAATGAGAAATGAGGGATTAAAAAAGATAAAAATAAGAGAAAATTTTCAGTTCT
TTTAAGAAAATAAAACATCT

Product: phosphoribosylglycinamide formyltransferase

Products: NA

Alternate protein names: 5'-phosphoribosylglycinamide transformylase; GAR transformylase; GART [H]

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MKIAVFASGNGSNFQRLAEQFPKVVKFVFSDHHDAYVLERADKLGVANASLELKEFTSKVDYEKALVEILEAQEIDLILL
AGYMKIIGSTMLARYKGKIINVHPSFLPDFAGSPHAIEESHEAKYGLGITIHYVDEGVDTGEIIAQIPVAYHESLEVYEE
RVHEAEHELYPKVVRQIILHQQ

Sequences:

>Translated_182_residues
MKIAVFASGNGSNFQRLAEQFPKVVKFVFSDHHDAYVLERADKLGVANASLELKEFTSKVDYEKALVEILEAQEIDLILL
AGYMKIIGSTMLARYKGKIINVHPSFLPDFAGSPHAIEESHEAKYGLGITIHYVDEGVDTGEIIAQIPVAYHESLEVYEE
RVHEAEHELYPKVVRQIILHQQ
>Mature_182_residues
MKIAVFASGNGSNFQRLAEQFPKVVKFVFSDHHDAYVLERADKLGVANASLELKEFTSKVDYEKALVEILEAQEIDLILL
AGYMKIIGSTMLARYKGKIINVHPSFLPDFAGSPHAIEESHEAKYGLGITIHYVDEGVDTGEIIAQIPVAYHESLEVYEE
RVHEAEHELYPKVVRQIILHQQ

Specific function: De novo purine biosynthesis; third step. [C]

COG id: COG0299

COG function: function code F; Folate-dependent phosphoribosylglycinamide formyltransferase PurN

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GART family [H]

Homologues:

Organism=Homo sapiens, GI4503915, Length=184, Percent_Identity=32.6086956521739, Blast_Score=109, Evalue=1e-24,
Organism=Homo sapiens, GI209869995, Length=184, Percent_Identity=32.6086956521739, Blast_Score=109, Evalue=1e-24,
Organism=Homo sapiens, GI209869993, Length=184, Percent_Identity=32.6086956521739, Blast_Score=109, Evalue=1e-24,
Organism=Escherichia coli, GI1788846, Length=184, Percent_Identity=33.695652173913, Blast_Score=109, Evalue=8e-26,
Organism=Escherichia coli, GI1787483, Length=92, Percent_Identity=32.6086956521739, Blast_Score=63, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17567511, Length=184, Percent_Identity=30.9782608695652, Blast_Score=95, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6320616, Length=210, Percent_Identity=30.4761904761905, Blast_Score=80, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24582400, Length=187, Percent_Identity=33.6898395721925, Blast_Score=116, Evalue=8e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002376
- InterPro:   IPR001555
- InterPro:   IPR004607 [H]

Pfam domain/function: PF00551 Formyl_trans_N [H]

EC number: =2.1.2.2 [H]

Molecular weight: Translated: 20506; Mature: 20506

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAVFASGNGSNFQRLAEQFPKVVKFVFSDHHDAYVLERADKLGVANASLELKEFTSKV
CEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHC
DYEKALVEILEAQEIDLILLAGYMKIIGSTMLARYKGKIINVHPSFLPDFAGSPHAIEES
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCC
HEAKYGLGITIHYVDEGVDTGEIIAQIPVAYHESLEVYEERVHEAEHELYPKVVRQIILH
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
QQ
CC
>Mature Secondary Structure
MKIAVFASGNGSNFQRLAEQFPKVVKFVFSDHHDAYVLERADKLGVANASLELKEFTSKV
CEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHC
DYEKALVEILEAQEIDLILLAGYMKIIGSTMLARYKGKIINVHPSFLPDFAGSPHAIEES
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCC
HEAKYGLGITIHYVDEGVDTGEIIAQIPVAYHESLEVYEERVHEAEHELYPKVVRQIILH
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
QQ
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3036807; 9384377 [H]