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The map label for this gene is clpB [H]

Identifier: 125623824

GI number: 125623824

Start: 948593

End: 951196

Strand: Direct

Name: clpB [H]

Synonym: llmg_0986

Alternate gene names: 125623824

Gene position: 948593-951196 (Clockwise)

Preceding gene: 125623823

Following gene: 125623825

Centisome position: 37.5

GC content: 38.98

Gene sequence:

>2604_bases
ATGGACATCGAAAAAATGACAACAACGATGCAAGAAGCACTTGGTTCAGCGCAACAAATTGCGCAAGTTCGTCATCACCA
AGTGATTGAAGTTCCACATTTATGGCGAATTTTTGTTCAACCTAATAGTTTTGGGGCGAACTTTTATAAAGATTTAGGGA
TTGACCTAGATGACTTTACAAATTTAATTGAAAAAGAAATTGACAAAATTAATTCGGTAGAAGGTTCAAATATTACTTAT
GGTCAAAACCTAAGTCCAGATTTGTTCCAAGTATTTACTGAAGCAGACAAAATTGCGCAAAAAATGGGCGATGAATACCT
ATCAACTGAGATTATTCTCCTTGCTCTCTTTGAATTAAAACAAAATCCATTGACCGAGTATTTGGTCAGCCATGGACTAA
CAAAAGCAAAAGCGCAAGCTGCGATTGAAAAATTACGTGGAGGTGATAAAGTGACCAGTCAAAATGCAGAAGAAACATAC
AAAGCACTTGAAAAATATGGGGTGGATCTCGTTGCTCAAGTTAAATCAGGCAATCAAGATCCCGTCATTGGACGTGATGA
AGAAATTCGTGATGTCATTCGAGTGCTTTCTCGTAAAACAAAAAACAATCCCGTTCTTATTGGTGAACCTGGGGTTGGTA
AAACAGCCATTGTCGAAGGATTGGCACAAAGGATTGTCAGAAAAGACGTTCCTGAAAATCTAAAAGATAAAACAATCTTT
TCACTGGATATGGGTGCCTTGATTGCAGGAGCGAAATATCGTGGTGAATTTGAAGAACGTTTGAAAGCAGTCCTTAATGA
AGTTAAAAAAGCTGATGGACAAATTATCCTTTTCATTGATGAACTTCATACCATTGTTGGTGCAGGTAAAACAGAAGGTT
CAATGGATGCTGGTAACCTTTTGAAACCAATGCTTGCACGTGGTGAACTCCATTTGATTGGGGCAACGACCTTGGATGAA
TATCGTAAATACATGGAAACAGATAAAGCACTTGAACGTCGTTTCCAAAAAGTATTGGTCACTGAGCCTACCGTTGAAGA
TACGATTTCAATCTTGCGTGGTCTAAAAGAACGTTTTGAAATTCACCATGGGGTGACCATTCATGATAATGCTTTAGTTG
CAGCAGCCACATTGTCAAATCGTTATATTACAGACCGTTTCTTACCAGATAAAGCGATCGACTTAATTGATGAAGCCAGT
GCAACGATTCGGGTGGAAATGAATTCACTCCCAACTGAACTTGACCAAGCCAATCGTCGCTTGATGCAATTAGAAATTGA
AGAAGCAGCCCTCAAAAAAGAACGGGATGATGCTTCTAAGAAACGTCTTGAAATTATACGTGGTGAAATTGCTGAACTTC
GAGAAGAAAATAATCAACTCAAAGCCCAATGGGAAGCTGAGAAAAAAGAAGTGGGCAATATTTCTGAAAAACGTAATGAA
TTAGAACATGCTCGCCACGAATTGGAAGAAGCCCAAAATGAAGGAAACTTAGAAAAAGCAGCAGCCCTTCGTTATGGTAA
AATTCCTGAAATTGAAAAAGAACTCAAAGCTATTGAAGAAAAAGCAAAATCAGATGATTTATCTTTAGTTCAAGAATCAG
TCACTGAAGAACAAATCGCCGAAGTGGTTGGACGGATGACTGGTATTCCAATTACCAAATTGGTTGAAGGTGAACGTGAA
AAATTACTTCATTTGCCAGAAACACTTCATCAAAGAGTTGTCGGACAAGATGAAGCTGTTGAAGCCGTATCTGATGCCAT
TATTCGTGCGCGTGCAGGAATTCAAGACCCTAACCGTCCACTTGGCTCATTCCTCTTCCTTGGACCAACTGGGGTAGGTA
AGACCGAACTTGCGAAAGCATTGGCTGAAAATCTCTTTGATTCAGAAGAACATATGGTTCGGATTGACATGAGTGAATAT
ATGGAAAAACACAGCGTGTCACGTTTAGTCGGAGCTCCTCCAGGATATGTCGGTTACGATGAAGGAGGCCAATTGACCGA
AGCCGTTCGCCGTAATCCTTATACCATCATCTTGCTTGATGAAATCGAAAAAGCACATCCAGATGTCTTCAATATCTTGT
TGCAAGTTTTAGATGACGGACGTTTGACCGACTCTAAAGGTGTTCTCGTCGACTTTAAGAATACAGTATTGATTATGACT
TCAAATGTCGGTTCTCAATATCTGCTCGATAATGTTGGAGAAAATGGTGAAATTTCTGAAGAAACAACAGAAAATGTGAT
GTCGCAACTTCGCGCGCATTTCAAACCAGAATTTTTAAACCGGATTGATGATACCATTCTTTTCAAACCATTGGCGCTTG
AAGACATCAAGAACATTATCCTTAAAATGACCAGTCAACTAGCACATCGTCTTGAAGAAATGGAAGTTGAGCTTGAATTG
AGTGAAGAAGTAAAAGTTTGGATTGCTGAAAATGCTTATGAACCTGCTTATGGTGCACGCCCACTCAAACGTTACTTGAC
AAAAGTCATCGAAAATCCATTAGCTAAGCTGATTATCGGAGGAAAAATTCCACCAAAATCAAAAGTTATTGTAAGGCTTA
TAGATAACAAGGTTGACTTTGATGTTCAATCGATTGCTGAATAA

Upstream 100 bases:

>100_bases
CAAAAAGTTTGACTATTACTGACCAATGTATTATAATTAGAATGTAGTGAGAAAAAGATAACAATCACTACCAACTATGA
AATCGAAATGAGGTGTTTTT

Downstream 100 bases:

>100_bases
ATAGATTAAACCGTTGGCTGATGCTGGCGGTTTTTTTATGTAGATATGTGAATATTTAAATAAACAAAAGCCTTATTTCC
GAACAATCCAATCAAAAAGT

Product: ATP-dependent Clp protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 867; Mature: 867

Protein sequence:

>867_residues
MDIEKMTTTMQEALGSAQQIAQVRHHQVIEVPHLWRIFVQPNSFGANFYKDLGIDLDDFTNLIEKEIDKINSVEGSNITY
GQNLSPDLFQVFTEADKIAQKMGDEYLSTEIILLALFELKQNPLTEYLVSHGLTKAKAQAAIEKLRGGDKVTSQNAEETY
KALEKYGVDLVAQVKSGNQDPVIGRDEEIRDVIRVLSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVRKDVPENLKDKTIF
SLDMGALIAGAKYRGEFEERLKAVLNEVKKADGQIILFIDELHTIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDE
YRKYMETDKALERRFQKVLVTEPTVEDTISILRGLKERFEIHHGVTIHDNALVAAATLSNRYITDRFLPDKAIDLIDEAS
ATIRVEMNSLPTELDQANRRLMQLEIEEAALKKERDDASKKRLEIIRGEIAELREENNQLKAQWEAEKKEVGNISEKRNE
LEHARHELEEAQNEGNLEKAAALRYGKIPEIEKELKAIEEKAKSDDLSLVQESVTEEQIAEVVGRMTGIPITKLVEGERE
KLLHLPETLHQRVVGQDEAVEAVSDAIIRARAGIQDPNRPLGSFLFLGPTGVGKTELAKALAENLFDSEEHMVRIDMSEY
MEKHSVSRLVGAPPGYVGYDEGGQLTEAVRRNPYTIILLDEIEKAHPDVFNILLQVLDDGRLTDSKGVLVDFKNTVLIMT
SNVGSQYLLDNVGENGEISEETTENVMSQLRAHFKPEFLNRIDDTILFKPLALEDIKNIILKMTSQLAHRLEEMEVELEL
SEEVKVWIAENAYEPAYGARPLKRYLTKVIENPLAKLIIGGKIPPKSKVIVRLIDNKVDFDVQSIAE

Sequences:

>Translated_867_residues
MDIEKMTTTMQEALGSAQQIAQVRHHQVIEVPHLWRIFVQPNSFGANFYKDLGIDLDDFTNLIEKEIDKINSVEGSNITY
GQNLSPDLFQVFTEADKIAQKMGDEYLSTEIILLALFELKQNPLTEYLVSHGLTKAKAQAAIEKLRGGDKVTSQNAEETY
KALEKYGVDLVAQVKSGNQDPVIGRDEEIRDVIRVLSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVRKDVPENLKDKTIF
SLDMGALIAGAKYRGEFEERLKAVLNEVKKADGQIILFIDELHTIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDE
YRKYMETDKALERRFQKVLVTEPTVEDTISILRGLKERFEIHHGVTIHDNALVAAATLSNRYITDRFLPDKAIDLIDEAS
ATIRVEMNSLPTELDQANRRLMQLEIEEAALKKERDDASKKRLEIIRGEIAELREENNQLKAQWEAEKKEVGNISEKRNE
LEHARHELEEAQNEGNLEKAAALRYGKIPEIEKELKAIEEKAKSDDLSLVQESVTEEQIAEVVGRMTGIPITKLVEGERE
KLLHLPETLHQRVVGQDEAVEAVSDAIIRARAGIQDPNRPLGSFLFLGPTGVGKTELAKALAENLFDSEEHMVRIDMSEY
MEKHSVSRLVGAPPGYVGYDEGGQLTEAVRRNPYTIILLDEIEKAHPDVFNILLQVLDDGRLTDSKGVLVDFKNTVLIMT
SNVGSQYLLDNVGENGEISEETTENVMSQLRAHFKPEFLNRIDDTILFKPLALEDIKNIILKMTSQLAHRLEEMEVELEL
SEEVKVWIAENAYEPAYGARPLKRYLTKVIENPLAKLIIGGKIPPKSKVIVRLIDNKVDFDVQSIAE
>Mature_867_residues
MDIEKMTTTMQEALGSAQQIAQVRHHQVIEVPHLWRIFVQPNSFGANFYKDLGIDLDDFTNLIEKEIDKINSVEGSNITY
GQNLSPDLFQVFTEADKIAQKMGDEYLSTEIILLALFELKQNPLTEYLVSHGLTKAKAQAAIEKLRGGDKVTSQNAEETY
KALEKYGVDLVAQVKSGNQDPVIGRDEEIRDVIRVLSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVRKDVPENLKDKTIF
SLDMGALIAGAKYRGEFEERLKAVLNEVKKADGQIILFIDELHTIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDE
YRKYMETDKALERRFQKVLVTEPTVEDTISILRGLKERFEIHHGVTIHDNALVAAATLSNRYITDRFLPDKAIDLIDEAS
ATIRVEMNSLPTELDQANRRLMQLEIEEAALKKERDDASKKRLEIIRGEIAELREENNQLKAQWEAEKKEVGNISEKRNE
LEHARHELEEAQNEGNLEKAAALRYGKIPEIEKELKAIEEKAKSDDLSLVQESVTEEQIAEVVGRMTGIPITKLVEGERE
KLLHLPETLHQRVVGQDEAVEAVSDAIIRARAGIQDPNRPLGSFLFLGPTGVGKTELAKALAENLFDSEEHMVRIDMSEY
MEKHSVSRLVGAPPGYVGYDEGGQLTEAVRRNPYTIILLDEIEKAHPDVFNILLQVLDDGRLTDSKGVLVDFKNTVLIMT
SNVGSQYLLDNVGENGEISEETTENVMSQLRAHFKPEFLNRIDDTILFKPLALEDIKNIILKMTSQLAHRLEEMEVELEL
SEEVKVWIAENAYEPAYGARPLKRYLTKVIENPLAKLIIGGKIPPKSKVIVRLIDNKVDFDVQSIAE

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=299, Percent_Identity=38.4615384615385, Blast_Score=194, Evalue=2e-49,
Organism=Escherichia coli, GI1788943, Length=853, Percent_Identity=55.2168815943728, Blast_Score=927, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=358, Percent_Identity=42.1787709497207, Blast_Score=280, Evalue=3e-76,
Organism=Saccharomyces cerevisiae, GI6320464, Length=745, Percent_Identity=50.4697986577181, Blast_Score=752, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=862, Percent_Identity=41.415313225058, Blast_Score=630, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 97328; Mature: 97328

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIEKMTTTMQEALGSAQQIAQVRHHQVIEVPHLWRIFVQPNSFGANFYKDLGIDLDDFT
CCHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHCCCCHHHHH
NLIEKEIDKINSVEGSNITYGQNLSPDLFQVFTEADKIAQKMGDEYLSTEIILLALFELK
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
QNPLTEYLVSHGLTKAKAQAAIEKLRGGDKVTSQNAEETYKALEKYGVDLVAQVKSGNQD
CCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHEEHHHCCCCC
PVIGRDEEIRDVIRVLSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVRKDVPENLKDKTIF
CCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEE
SLDMGALIAGAKYRGEFEERLKAVLNEVKKADGQIILFIDELHTIVGAGKTEGSMDAGNL
EECHHHHHHCCHHCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCHHHH
LKPMLARGELHLIGATTLDEYRKYMETDKALERRFQKVLVTEPTVEDTISILRGLKERFE
HHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
IHHGVTIHDNALVAAATLSNRYITDRFLPDKAIDLIDEASATIRVEMNSLPTELDQANRR
HHCCEEEECCCEEEEEHHCCCCHHHHCCCHHHHHHHHCCCCEEEEECCCCCCHHHHHHHH
LMQLEIEEAALKKERDDASKKRLEIIRGEIAELREENNQLKAQWEAEKKEVGNISEKRNE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHH
LEHARHELEEAQNEGNLEKAAALRYGKIPEIEKELKAIEEKAKSDDLSLVQESVTEEQIA
HHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
EVVGRMTGIPITKLVEGEREKLLHLPETLHQRVVGQDEAVEAVSDAIIRARAGIQDPNRP
HHHHHHCCCCHHHHHCCHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCC
LGSFLFLGPTGVGKTELAKALAENLFDSEEHMVRIDMSEYMEKHSVSRLVGAPPGYVGYD
CCCEEEECCCCCCHHHHHHHHHHHHCCCCHHEEEECHHHHHHHHHHHHHHCCCCCCCCCC
EGGQLTEAVRRNPYTIILLDEIEKAHPDVFNILLQVLDDGRLTDSKGVLVDFKNTVLIMT
CCCHHHHHHHCCCCEEEEECCHHHHCCHHHHHHHHHHCCCCCCCCCCEEEEECCEEEEEE
SNVGSQYLLDNVGENGEISEETTENVMSQLRAHFKPEFLNRIDDTILFKPLALEDIKNII
CCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHH
LKMTSQLAHRLEEMEVELELSEEVKVWIAENAYEPAYGARPLKRYLTKVIENPLAKLIIG
HHHHHHHHHHHHHHHHHEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
GKIPPKSKVIVRLIDNKVDFDVQSIAE
CCCCCCHHHHHHHHCCCCCCCHHHHCC
>Mature Secondary Structure
MDIEKMTTTMQEALGSAQQIAQVRHHQVIEVPHLWRIFVQPNSFGANFYKDLGIDLDDFT
CCHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHCCCCHHHHH
NLIEKEIDKINSVEGSNITYGQNLSPDLFQVFTEADKIAQKMGDEYLSTEIILLALFELK
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
QNPLTEYLVSHGLTKAKAQAAIEKLRGGDKVTSQNAEETYKALEKYGVDLVAQVKSGNQD
CCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHEEHHHCCCCC
PVIGRDEEIRDVIRVLSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVRKDVPENLKDKTIF
CCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEE
SLDMGALIAGAKYRGEFEERLKAVLNEVKKADGQIILFIDELHTIVGAGKTEGSMDAGNL
EECHHHHHHCCHHCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCHHHH
LKPMLARGELHLIGATTLDEYRKYMETDKALERRFQKVLVTEPTVEDTISILRGLKERFE
HHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
IHHGVTIHDNALVAAATLSNRYITDRFLPDKAIDLIDEASATIRVEMNSLPTELDQANRR
HHCCEEEECCCEEEEEHHCCCCHHHHCCCHHHHHHHHCCCCEEEEECCCCCCHHHHHHHH
LMQLEIEEAALKKERDDASKKRLEIIRGEIAELREENNQLKAQWEAEKKEVGNISEKRNE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHH
LEHARHELEEAQNEGNLEKAAALRYGKIPEIEKELKAIEEKAKSDDLSLVQESVTEEQIA
HHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
EVVGRMTGIPITKLVEGEREKLLHLPETLHQRVVGQDEAVEAVSDAIIRARAGIQDPNRP
HHHHHHCCCCHHHHHCCHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCC
LGSFLFLGPTGVGKTELAKALAENLFDSEEHMVRIDMSEYMEKHSVSRLVGAPPGYVGYD
CCCEEEECCCCCCHHHHHHHHHHHHCCCCHHEEEECHHHHHHHHHHHHHHCCCCCCCCCC
EGGQLTEAVRRNPYTIILLDEIEKAHPDVFNILLQVLDDGRLTDSKGVLVDFKNTVLIMT
CCCHHHHHHHCCCCEEEEECCHHHHCCHHHHHHHHHHCCCCCCCCCCEEEEECCEEEEEE
SNVGSQYLLDNVGENGEISEETTENVMSQLRAHFKPEFLNRIDDTILFKPLALEDIKNII
CCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHH
LKMTSQLAHRLEEMEVELELSEEVKVWIAENAYEPAYGARPLKRYLTKVIENPLAKLIIG
HHHHHHHHHHHHHHHHHEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
GKIPPKSKVIVRLIDNKVDFDVQSIAE
CCCCCCHHHHHHHHCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]