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The map label for this gene is murG [H]

Identifier: 125623756

GI number: 125623756

Start: 880051

End: 881124

Strand: Direct

Name: murG [H]

Synonym: llmg_0913

Alternate gene names: 125623756

Gene position: 880051-881124 (Clockwise)

Preceding gene: 125623755

Following gene: 125623757

Centisome position: 34.79

GC content: 36.5

Gene sequence:

>1074_bases
ATGCGAATTATCATTACAGGTGGCGGCACAGGTGGTCATATTTACCCAGCCCTAGCTTTCCTGAAATATTTAAAACAAGA
GGAACCAGATACAGAGGTCCTTTATATTGGAACTAAAAAAGGTCTAGAATCTAAAATTGTTCCACGAGCAGGAATTCAAT
TGAAAACAGTTGATATTCAAGGGCTAAGACGTTCATTAAGTCCACAAAATATAAAAACTGCCTATAAATTTTTTAAATCA
GTATCAGATGCTAAAAAAATTATGAAGGATTTTAAGCCAGATGTTGTGTTAGGAACTGGTGGATATGTGGCAGGACCAGT
CGTTTTTGCAGCGGCACAATTGAAAATTCCAACAATTATTCATGAAGGAAACTCATTTCCAGGAATTACCAATCGTTTTC
TTGCCAAAAAAGTTGACCGAATTGCCGTAGGTTTCCATGCAGCGGAGCAATATTTTCCTAGTGAGAAAACAAGTTTCACA
GGGAATCCAAGAGCACAAGAAGTTGCTGATGCAGCTGCTCAAGTTGAAAAGTTTGAACAACCAACAGTAGTGATTTTTGG
GGGGTCTCGTGGAGCTTTAAAACTTAATAATGCTTTTATTGAAGCCCTGCCTGAATTGGCTAAACGTTCATTCAAAACAG
TTTATGCTTCAGGTGAGATTTATTATGATGATTACAAAGAAACTTTTGATCAATATAAAGAAAATCCAAATTTAGATATT
CGACCTTACATCAATAATATGACTGAACTTTTAGCAAAAAGTCAACTTTTTTTAGGGCGTTCTGGCTCAACAACAATCGC
AGAAGTGACAGCTTTAGGTTTACCAGCGGTTTATGTTCCTAGTCCAAATGTCACAGCAGACCAACAAACTAAAAATGCTC
AAGAATACGTTGATCAAGGAGCAGCAATTATTGTAAAAGATGAAGAATTGAATGGTCAAAGTTTAGTCGAAGCGATTTCA
GATATTCTTGAAAACACAGAAAAATATCAAGAAATGCAAAGAGCTAGTCTAAAAGCAGGCGTTCCAGATGCTAGCCAACG
CCTTTACAATCTAGTGAAAGAGATTAGTAACTAA

Upstream 100 bases:

>100_bases
CTTTTTTTCGATTTAATGATTTGAGTGAAGAAGATAGCGGTTAAAGCTCAAAAAGTTTAGATCTATCAGCGAATCCCCAA
ACCATTGGAGAAGAATAAAT

Downstream 100 bases:

>100_bases
ATGAGTGAAAAAGATAATAACTTAACCCCTTGGCAGCAAAAACATCTTGAATATCAGAAAAGAAAAGCTGAAGAAGCTAA
AAAAGAAAAGAAAGCAAATC

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase [H]

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MRIIITGGGTGGHIYPALAFLKYLKQEEPDTEVLYIGTKKGLESKIVPRAGIQLKTVDIQGLRRSLSPQNIKTAYKFFKS
VSDAKKIMKDFKPDVVLGTGGYVAGPVVFAAAQLKIPTIIHEGNSFPGITNRFLAKKVDRIAVGFHAAEQYFPSEKTSFT
GNPRAQEVADAAAQVEKFEQPTVVIFGGSRGALKLNNAFIEALPELAKRSFKTVYASGEIYYDDYKETFDQYKENPNLDI
RPYINNMTELLAKSQLFLGRSGSTTIAEVTALGLPAVYVPSPNVTADQQTKNAQEYVDQGAAIIVKDEELNGQSLVEAIS
DILENTEKYQEMQRASLKAGVPDASQRLYNLVKEISN

Sequences:

>Translated_357_residues
MRIIITGGGTGGHIYPALAFLKYLKQEEPDTEVLYIGTKKGLESKIVPRAGIQLKTVDIQGLRRSLSPQNIKTAYKFFKS
VSDAKKIMKDFKPDVVLGTGGYVAGPVVFAAAQLKIPTIIHEGNSFPGITNRFLAKKVDRIAVGFHAAEQYFPSEKTSFT
GNPRAQEVADAAAQVEKFEQPTVVIFGGSRGALKLNNAFIEALPELAKRSFKTVYASGEIYYDDYKETFDQYKENPNLDI
RPYINNMTELLAKSQLFLGRSGSTTIAEVTALGLPAVYVPSPNVTADQQTKNAQEYVDQGAAIIVKDEELNGQSLVEAIS
DILENTEKYQEMQRASLKAGVPDASQRLYNLVKEISN
>Mature_357_residues
MRIIITGGGTGGHIYPALAFLKYLKQEEPDTEVLYIGTKKGLESKIVPRAGIQLKTVDIQGLRRSLSPQNIKTAYKFFKS
VSDAKKIMKDFKPDVVLGTGGYVAGPVVFAAAQLKIPTIIHEGNSFPGITNRFLAKKVDRIAVGFHAAEQYFPSEKTSFT
GNPRAQEVADAAAQVEKFEQPTVVIFGGSRGALKLNNAFIEALPELAKRSFKTVYASGEIYYDDYKETFDQYKENPNLDI
RPYINNMTELLAKSQLFLGRSGSTTIAEVTALGLPAVYVPSPNVTADQQTKNAQEYVDQGAAIIVKDEELNGQSLVEAIS
DILENTEKYQEMQRASLKAGVPDASQRLYNLVKEISN

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) [H]

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786278, Length=365, Percent_Identity=31.7808219178082, Blast_Score=177, Evalue=1e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235 [H]

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28 [H]

EC number: =2.4.1.227 [H]

Molecular weight: Translated: 39227; Mature: 39227

Theoretical pI: Translated: 8.53; Mature: 8.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIIITGGGTGGHIYPALAFLKYLKQEEPDTEVLYIGTKKGLESKIVPRAGIQLKTVDIQ
CEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEEEHH
GLRRSLSPQNIKTAYKFFKSVSDAKKIMKDFKPDVVLGTGGYVAGPVVFAAAQLKIPTII
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHEECCEEE
HEGNSFPGITNRFLAKKVDRIAVGFHAAEQYFPSEKTSFTGNPRAQEVADAAAQVEKFEQ
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
PTVVIFGGSRGALKLNNAFIEALPELAKRSFKTVYASGEIYYDDYKETFDQYKENPNLDI
CEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHEEEECCCEEECHHHHHHHHHHCCCCCEE
RPYINNMTELLAKSQLFLGRSGSTTIAEVTALGLPAVYVPSPNVTADQQTKNAQEYVDQG
CHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHCC
AAIIVKDEELNGQSLVEAISDILENTEKYQEMQRASLKAGVPDASQRLYNLVKEISN
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRIIITGGGTGGHIYPALAFLKYLKQEEPDTEVLYIGTKKGLESKIVPRAGIQLKTVDIQ
CEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEEEHH
GLRRSLSPQNIKTAYKFFKSVSDAKKIMKDFKPDVVLGTGGYVAGPVVFAAAQLKIPTII
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHEECCEEE
HEGNSFPGITNRFLAKKVDRIAVGFHAAEQYFPSEKTSFTGNPRAQEVADAAAQVEKFEQ
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
PTVVIFGGSRGALKLNNAFIEALPELAKRSFKTVYASGEIYYDDYKETFDQYKENPNLDI
CEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHEEEECCCEEECHHHHHHHHHHCCCCCEE
RPYINNMTELLAKSQLFLGRSGSTTIAEVTALGLPAVYVPSPNVTADQQTKNAQEYVDQG
CHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHCC
AAIIVKDEELNGQSLVEAISDILENTEKYQEMQRASLKAGVPDASQRLYNLVKEISN
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]