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The map label for this gene is aroD

Identifier: 125623633

GI number: 125623633

Start: 770763

End: 771452

Strand: Direct

Name: aroD

Synonym: llmg_0782

Alternate gene names: 125623633

Gene position: 770763-771452 (Clockwise)

Preceding gene: 125623632

Following gene: 125623634

Centisome position: 30.47

GC content: 34.78

Gene sequence:

>690_bases
ATGAGAAGAACAAAAATTGTTGTTCCAATAATGCTGACAGAGTTAACAGAGCTTGAGAAAGTTTCTGTCAGTGATTATCA
TTCAGCAGATATTGTTGAATGGCGTGCCGATTTTTTGTCAGCAGATGATATTTTTGAGATGGCCCCTAAATTCTTTGAAA
AATTTAAAGAGAGCAAGATTCTATTTACTTTAAGAACGGTCAGAGAAGGTGGAAATATTCAGGTTTCTGAGAAAAAATAT
TTACAGATTTTACAAGAAATTTTAAAGTTTGATCCAGATTATATTGATGTTGAATATTTCAGTCATGGGCCTTCATTTGC
TGCTTTAAAGAATTATCGTGAAAAAATTGTCCTTTCATATCATAACTTTGATGAAGTTCCGACCGATTTGACCAGTCGTT
TGATTAAAATGCATGAAGAAGGAACGGCTTTTGTGAAAGTGGCTGTGATGCCTGAACGTGAATGTGATGTGCTTGATTTA
TTGCAGATTACTCGCGATATGACTTTAGAATATGGAAATCATTTTATCAGTATGGCAATGGGTGATTTGGGACGTCTTTC
AAGAATTTCAGGTTATTTGACTGGCTCTTGTTGGACTTTTGCAAGTCTGGAAAACTCAAGCGCTCCTGGACAAATTTCAT
TAAAGGAAACAGTAGAGATTTTGGATCTTTTAGAAAATGAGTTGGCTTAA

Upstream 100 bases:

>100_bases
CCAGTAAAAAAACTTTAAAGGAAACGTTGTTTCCTTTTTTCTTTTTACTAAAATATGATAGAATAGGGGAAAGCATTTAT
GAAAATGTAAGGAGAAGTTT

Downstream 100 bases:

>100_bases
GGATTGAATGCTTATTGTTCGGTTTTGACAGATAATATTTTTACTTTTATTAATATTGACAGAAATCTCCAAAGTCATTA
GACTTGAAAATGATATAATA

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type I DHQase

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MRRTKIVVPIMLTELTELEKVSVSDYHSADIVEWRADFLSADDIFEMAPKFFEKFKESKILFTLRTVREGGNIQVSEKKY
LQILQEILKFDPDYIDVEYFSHGPSFAALKNYREKIVLSYHNFDEVPTDLTSRLIKMHEEGTAFVKVAVMPERECDVLDL
LQITRDMTLEYGNHFISMAMGDLGRLSRISGYLTGSCWTFASLENSSAPGQISLKETVEILDLLENELA

Sequences:

>Translated_229_residues
MRRTKIVVPIMLTELTELEKVSVSDYHSADIVEWRADFLSADDIFEMAPKFFEKFKESKILFTLRTVREGGNIQVSEKKY
LQILQEILKFDPDYIDVEYFSHGPSFAALKNYREKIVLSYHNFDEVPTDLTSRLIKMHEEGTAFVKVAVMPERECDVLDL
LQITRDMTLEYGNHFISMAMGDLGRLSRISGYLTGSCWTFASLENSSAPGQISLKETVEILDLLENELA
>Mature_229_residues
MRRTKIVVPIMLTELTELEKVSVSDYHSADIVEWRADFLSADDIFEMAPKFFEKFKESKILFTLRTVREGGNIQVSEKKY
LQILQEILKFDPDYIDVEYFSHGPSFAALKNYREKIVLSYHNFDEVPTDLTSRLIKMHEEGTAFVKVAVMPERECDVLDL
LQITRDMTLEYGNHFISMAMGDLGRLSRISGYLTGSCWTFASLENSSAPGQISLKETVEILDLLENELA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; third step. [C]

COG id: COG0710

COG function: function code E; 3-dehydroquinate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I 3-dehydroquinase family

Homologues:

Organism=Escherichia coli, GI1787984, Length=236, Percent_Identity=30.9322033898305, Blast_Score=111, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROD_LACLM (A2RJD1)

Other databases:

- EMBL:   AM406671
- RefSeq:   YP_001032116.1
- ProteinModelPortal:   A2RJD1
- SMR:   A2RJD1
- STRING:   A2RJD1
- GeneID:   4798537
- GenomeReviews:   AM406671_GR
- KEGG:   llm:llmg_0782
- eggNOG:   COG0710
- HOGENOM:   HBG732926
- OMA:   SYHNFDE
- ProtClustDB:   PRK02412
- HAMAP:   MF_00214
- InterPro:   IPR013785
- InterPro:   IPR001381
- Gene3D:   G3DSA:3.20.20.70
- TIGRFAMs:   TIGR01093

Pfam domain/function: PF01487 DHquinase_I

EC number: =4.2.1.10

Molecular weight: Translated: 26309; Mature: 26309

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS01028 DEHYDROQUINASE_I

Important sites: ACT_SITE 121-121 ACT_SITE 146-146

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRTKIVVPIMLTELTELEKVSVSDYHSADIVEWRADFLSADDIFEMAPKFFEKFKESKI
CCCCEEEHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCEE
LFTLRTVREGGNIQVSEKKYLQILQEILKFDPDYIDVEYFSHGPSFAALKNYREKIVLSY
EEEEEEHHCCCCEEECHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHEEEEE
HNFDEVPTDLTSRLIKMHEEGTAFVKVAVMPERECDVLDLLQITRDMTLEYGNHFISMAM
CCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GDLGRLSRISGYLTGSCWTFASLENSSAPGQISLKETVEILDLLENELA
HHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRRTKIVVPIMLTELTELEKVSVSDYHSADIVEWRADFLSADDIFEMAPKFFEKFKESKI
CCCCEEEHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCEE
LFTLRTVREGGNIQVSEKKYLQILQEILKFDPDYIDVEYFSHGPSFAALKNYREKIVLSY
EEEEEEHHCCCCEEECHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHEEEEE
HNFDEVPTDLTSRLIKMHEEGTAFVKVAVMPERECDVLDLLQITRDMTLEYGNHFISMAM
CCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GDLGRLSRISGYLTGSCWTFASLENSSAPGQISLKETVEILDLLENELA
HHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA