Click here to switch to the map view.

The map label for this gene is pepQ [H]

Identifier: 125623626

GI number: 125623626

Start: 763002

End: 764090

Strand: Reverse

Name: pepQ [H]

Synonym: llmg_0774

Alternate gene names: 125623626

Gene position: 764090-763002 (Counterclockwise)

Preceding gene: 125623641

Following gene: 125623619

Centisome position: 30.21

GC content: 38.02

Gene sequence:

>1089_bases
TTGAGCAAAATTGAACGTATTTCAGCCTTTCTGAATGATAAAGAAGTCGATATGACTTTCATCACTAATCCGACAACTCT
AAATTATCTAACAGGGCTAGCAATTGATCCCCATGAACGAATTGCTGGTTTGATGATTTTCAGAGATTCTAACCCTATGT
TATTCACCCCTGCCTTAGAAGTTGAAAAAGCTAAAGAACATACAAGTGGCCTAGATATTTTTGGTTATGACGATTCTCAA
AACCCTTGGGAAGTTGTTAAAAACCATGTAAAATCAGAAGTCAAATCAATTGCTGTTGAGTTCTCAGATATTCCTTTAGC
TAAAACAGAAGGTTTGAAAGCACAATTTGGTGATATTAATTTTGTGAACTTGACTCCATTAATTGAACGGATGCGTTTGA
TTAAATCAGCAGATGAAATTGAAAAAATGAAAATTGCTGGGGATTTTGCTGATAAGTGTTTTGAAATTGGTTTTGCTACT
GCTGCCGAACGTAATGGCGTCACTGAATCTGACATTGTCGCAAAGATTGAATACGAAATGAAACGTATGGGTGTTCCTCA
AATGTCATTTGATACGTTAGTACTATCAGGTGCTCGCGCAGCAAATCCTCATGGAGGACCTGAAAATGTCGAAATTCAAG
AAAATAAGCTTCTGCTCTTTGACTTAGGAGTGATGAGTGGCGGCTATGCATCTGATGCAACACGTACTATTGCTATTGGT
CAACCTAATGATTTTGATGCTGAAATCCATAAGATTGTTAAAGAGGCACAACAAGCCGCAATGGACTTCATTAAACCAGG
TGTGACTGCTCAAGAAGTTGATGCGGTTGCTCGTGATTTGATTACTAAAGCAGGTTATGGTGAATACTTCAACCATCGTC
TTGGGCATGGTATTGGAATGGATGTTCATGAGTATCCATCAATTGTGGCCGGAAATGACCTCGTCATTCAAGAAGGAATG
TGTTTCTCTAATGAGCCTGGAATTTATATTCCTGGTAAAGTGGGCGTTCGTATTGAGGATTGCCTTTATGTAACTGATAA
TGGTTGTGAAAGTTTCACTCATACTGACCATGATTTATTAATCTTCTAA

Upstream 100 bases:

>100_bases
CGTGATTTTTCAATAAAAATAGCGTAGAATGGATATATAGTGTTTTTTATTTTCAGGAGAATTTAGAAAACTTATTTTCA
TTAATATTGGAGGAACCATT

Downstream 100 bases:

>100_bases
TAAAATAAAATTAAAAACTTTCGCCAAAATTGGCGAAAGTTTTTTACTGACAAATAATTTTTCAATAGAAAAAATAATCA
TCGCAAAGATGATTATTTTT

Product: proline dipeptidase

Products: NA

Alternate protein names: X-Pro dipeptidase; Imidodipeptidase; Proline dipeptidase; Prolidase [H]

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MSKIERISAFLNDKEVDMTFITNPTTLNYLTGLAIDPHERIAGLMIFRDSNPMLFTPALEVEKAKEHTSGLDIFGYDDSQ
NPWEVVKNHVKSEVKSIAVEFSDIPLAKTEGLKAQFGDINFVNLTPLIERMRLIKSADEIEKMKIAGDFADKCFEIGFAT
AAERNGVTESDIVAKIEYEMKRMGVPQMSFDTLVLSGARAANPHGGPENVEIQENKLLLFDLGVMSGGYASDATRTIAIG
QPNDFDAEIHKIVKEAQQAAMDFIKPGVTAQEVDAVARDLITKAGYGEYFNHRLGHGIGMDVHEYPSIVAGNDLVIQEGM
CFSNEPGIYIPGKVGVRIEDCLYVTDNGCESFTHTDHDLLIF

Sequences:

>Translated_362_residues
MSKIERISAFLNDKEVDMTFITNPTTLNYLTGLAIDPHERIAGLMIFRDSNPMLFTPALEVEKAKEHTSGLDIFGYDDSQ
NPWEVVKNHVKSEVKSIAVEFSDIPLAKTEGLKAQFGDINFVNLTPLIERMRLIKSADEIEKMKIAGDFADKCFEIGFAT
AAERNGVTESDIVAKIEYEMKRMGVPQMSFDTLVLSGARAANPHGGPENVEIQENKLLLFDLGVMSGGYASDATRTIAIG
QPNDFDAEIHKIVKEAQQAAMDFIKPGVTAQEVDAVARDLITKAGYGEYFNHRLGHGIGMDVHEYPSIVAGNDLVIQEGM
CFSNEPGIYIPGKVGVRIEDCLYVTDNGCESFTHTDHDLLIF
>Mature_361_residues
SKIERISAFLNDKEVDMTFITNPTTLNYLTGLAIDPHERIAGLMIFRDSNPMLFTPALEVEKAKEHTSGLDIFGYDDSQN
PWEVVKNHVKSEVKSIAVEFSDIPLAKTEGLKAQFGDINFVNLTPLIERMRLIKSADEIEKMKIAGDFADKCFEIGFATA
AERNGVTESDIVAKIEYEMKRMGVPQMSFDTLVLSGARAANPHGGPENVEIQENKLLLFDLGVMSGGYASDATRTIAIGQ
PNDFDAEIHKIVKEAQQAAMDFIKPGVTAQEVDAVARDLITKAGYGEYFNHRLGHGIGMDVHEYPSIVAGNDLVIQEGMC
FSNEPGIYIPGKVGVRIEDCLYVTDNGCESFTHTDHDLLIF

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=251, Percent_Identity=32.2709163346614, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI93141226, Length=164, Percent_Identity=33.5365853658537, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI264681563, Length=191, Percent_Identity=28.7958115183246, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1788728, Length=317, Percent_Identity=33.7539432176656, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1789275, Length=262, Percent_Identity=28.2442748091603, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1786364, Length=263, Percent_Identity=24.3346007604563, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17509539, Length=302, Percent_Identity=25.4966887417219, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71989583, Length=255, Percent_Identity=23.921568627451, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6321118, Length=295, Percent_Identity=26.1016949152542, Blast_Score=73, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6320922, Length=254, Percent_Identity=23.2283464566929, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6322999, Length=161, Percent_Identity=33.5403726708075, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI19920384, Length=255, Percent_Identity=28.6274509803922, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI17137632, Length=377, Percent_Identity=26.525198938992, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21355531, Length=242, Percent_Identity=24.7933884297521, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: =3.4.13.9 [H]

Molecular weight: Translated: 39960; Mature: 39829

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIERISAFLNDKEVDMTFITNPTTLNYLTGLAIDPHERIAGLMIFRDSNPMLFTPALE
CCHHHHHHHHHCCCCEEEEEEECCCEEHHHCCCEECHHHHHEEEEEEECCCCEEEECCHH
VEKAKEHTSGLDIFGYDDSQNPWEVVKNHVKSEVKSIAVEFSDIPLAKTEGLKAQFGDIN
HHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCEE
FVNLTPLIERMRLIKSADEIEKMKIAGDFADKCFEIGFATAAERNGVTESDIVAKIEYEM
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
KRMGVPQMSFDTLVLSGARAANPHGGPENVEIQENKLLLFDLGVMSGGYASDATRTIAIG
HHCCCCCCCCCCEEEECCCCCCCCCCCCCEEEECCEEEEEEECCCCCCCCCCCCEEEEEC
QPNDFDAEIHKIVKEAQQAAMDFIKPGVTAQEVDAVARDLITKAGYGEYFNHRLGHGIGM
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCC
DVHEYPSIVAGNDLVIQEGMCFSNEPGIYIPGKVGVRIEDCLYVTDNGCESFTHTDHDLL
CHHHCCCEECCCCEEEECCCCCCCCCCEEECCCCCEEEEEEEEEECCCCCCCCCCCCCEE
IF
EC
>Mature Secondary Structure 
SKIERISAFLNDKEVDMTFITNPTTLNYLTGLAIDPHERIAGLMIFRDSNPMLFTPALE
CHHHHHHHHHCCCCEEEEEEECCCEEHHHCCCEECHHHHHEEEEEEECCCCEEEECCHH
VEKAKEHTSGLDIFGYDDSQNPWEVVKNHVKSEVKSIAVEFSDIPLAKTEGLKAQFGDIN
HHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCEE
FVNLTPLIERMRLIKSADEIEKMKIAGDFADKCFEIGFATAAERNGVTESDIVAKIEYEM
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
KRMGVPQMSFDTLVLSGARAANPHGGPENVEIQENKLLLFDLGVMSGGYASDATRTIAIG
HHCCCCCCCCCCEEEECCCCCCCCCCCCCEEEECCEEEEEEECCCCCCCCCCCCEEEEEC
QPNDFDAEIHKIVKEAQQAAMDFIKPGVTAQEVDAVARDLITKAGYGEYFNHRLGHGIGM
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCC
DVHEYPSIVAGNDLVIQEGMCFSNEPGIYIPGKVGVRIEDCLYVTDNGCESFTHTDHDLL
CHHHCCCEECCCCEEEECCCCCCCCCCEEECCCCCEEEEEEEEEECCCCCCCCCCCCCEE
IF
EC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA