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The map label for this gene is udk [H]

Identifier: 125623616

GI number: 125623616

Start: 751263

End: 751883

Strand: Direct

Name: udk [H]

Synonym: llmg_0762

Alternate gene names: 125623616

Gene position: 751263-751883 (Clockwise)

Preceding gene: 125623614

Following gene: 125623617

Centisome position: 29.7

GC content: 36.88

Gene sequence:

>621_bases
TTGAAGAAAACGTTGATTATTGGTGTCACTGGCGGTTCGGCAAGTGGAAAGACAAGTGTTTCACATGCTATTTTAGAAAC
TTTTTCAAATGAAAGAATTGCGATGATTGAGCATGATAGCTACTATAAAGACCAATCGCATTTGACTTTTGAAGAACGAA
CAAAAACGAACTATGATCATCCCTTAGCCTTTGATACAGATTATTTAATTGCTCAATTAAAAGAGCTTCAATACGGACGT
GCGGTTGACATCCCGATTTATGATTATGCTAAGCATACTCGCTCTCAAGAAACTTACCGCCAAGAGCCTGTTGATGTTTT
GATTGTTGAAGGAATTTTGGTTTTAGAAGACGAGCGTTTGCGTGACTTAATGGATATCAAAATTTTTGTGGATACTGATG
ATGATGTGCGTATCATTCGTCGAATTCGCCGAGATATTGAGGAAAGAGGAAGAACTCTAGACTCAGTAATTACACAATAT
CTAGAAGCTGTCAAACCAATGTACCATCAGTTTATTGAACCTACTAAGAGATACGCTGACGTCATTATACCTGAAGGTGT
TTCTAATACAGTTGGGGTCGATATTATAACGACAAAAATTGCTAGTATTCTAAATGACTAA

Upstream 100 bases:

>100_bases
TTTTTGATGTGAACGCTTAAAAAATAAAAAATTGTCAGTTGATGACAAAAAGCCCAAAAATTGTGGTAGAATATATAGAA
GAAAATTTGGAGATTTGATT

Downstream 100 bases:

>100_bases
AAAAACTGTCTGCTGACAGTTTTTAATTTTTATTTAGTGAATATCGTGAAAAATTAGTGAAATAAAAGCGCTTCTTGTCC
TTAAATAGCAATAATGGTAA

Product: uridine kinase

Products: NA

Alternate protein names: Cytidine monophosphokinase; Uridine monophosphokinase [H]

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MKKTLIIGVTGGSASGKTSVSHAILETFSNERIAMIEHDSYYKDQSHLTFEERTKTNYDHPLAFDTDYLIAQLKELQYGR
AVDIPIYDYAKHTRSQETYRQEPVDVLIVEGILVLEDERLRDLMDIKIFVDTDDDVRIIRRIRRDIEERGRTLDSVITQY
LEAVKPMYHQFIEPTKRYADVIIPEGVSNTVGVDIITTKIASILND

Sequences:

>Translated_206_residues
MKKTLIIGVTGGSASGKTSVSHAILETFSNERIAMIEHDSYYKDQSHLTFEERTKTNYDHPLAFDTDYLIAQLKELQYGR
AVDIPIYDYAKHTRSQETYRQEPVDVLIVEGILVLEDERLRDLMDIKIFVDTDDDVRIIRRIRRDIEERGRTLDSVITQY
LEAVKPMYHQFIEPTKRYADVIIPEGVSNTVGVDIITTKIASILND
>Mature_206_residues
MKKTLIIGVTGGSASGKTSVSHAILETFSNERIAMIEHDSYYKDQSHLTFEERTKTNYDHPLAFDTDYLIAQLKELQYGR
AVDIPIYDYAKHTRSQETYRQEPVDVLIVEGILVLEDERLRDLMDIKIFVDTDDDVRIIRRIRRDIEERGRTLDSVITQY
LEAVKPMYHQFIEPTKRYADVIIPEGVSNTVGVDIITTKIASILND

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uridine kinase family [H]

Homologues:

Organism=Homo sapiens, GI301129207, Length=207, Percent_Identity=43.4782608695652, Blast_Score=189, Evalue=1e-48,
Organism=Homo sapiens, GI57863312, Length=207, Percent_Identity=43.4782608695652, Blast_Score=189, Evalue=1e-48,
Organism=Homo sapiens, GI18699734, Length=213, Percent_Identity=42.7230046948357, Blast_Score=188, Evalue=3e-48,
Organism=Homo sapiens, GI13899253, Length=216, Percent_Identity=42.5925925925926, Blast_Score=176, Evalue=9e-45,
Organism=Homo sapiens, GI209863022, Length=152, Percent_Identity=39.4736842105263, Blast_Score=113, Evalue=1e-25,
Organism=Escherichia coli, GI87082034, Length=206, Percent_Identity=49.5145631067961, Blast_Score=222, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI17539892, Length=209, Percent_Identity=43.0622009569378, Blast_Score=179, Evalue=6e-46,
Organism=Caenorhabditis elegans, GI17539894, Length=209, Percent_Identity=43.0622009569378, Blast_Score=179, Evalue=7e-46,
Organism=Caenorhabditis elegans, GI71981181, Length=210, Percent_Identity=37.1428571428571, Blast_Score=131, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6324339, Length=194, Percent_Identity=36.0824742268041, Blast_Score=117, Evalue=9e-28,
Organism=Saccharomyces cerevisiae, GI6320223, Length=206, Percent_Identity=27.1844660194175, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI221458995, Length=219, Percent_Identity=41.5525114155251, Blast_Score=174, Evalue=4e-44,
Organism=Drosophila melanogaster, GI24649624, Length=217, Percent_Identity=41.9354838709677, Blast_Score=173, Evalue=7e-44,
Organism=Drosophila melanogaster, GI28573516, Length=202, Percent_Identity=40.5940594059406, Blast_Score=171, Evalue=3e-43,
Organism=Drosophila melanogaster, GI28573514, Length=202, Percent_Identity=40.5940594059406, Blast_Score=171, Evalue=3e-43,
Organism=Drosophila melanogaster, GI28573512, Length=202, Percent_Identity=40.5940594059406, Blast_Score=171, Evalue=3e-43,
Organism=Drosophila melanogaster, GI45550449, Length=202, Percent_Identity=40.5940594059406, Blast_Score=171, Evalue=4e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006083
- InterPro:   IPR000764 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.48 [H]

Molecular weight: Translated: 23754; Mature: 23754

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTLIIGVTGGSASGKTSVSHAILETFSNERIAMIEHDSYYKDQSHLTFEERTKTNYDH
CCCEEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHCCCCCC
PLAFDTDYLIAQLKELQYGRAVDIPIYDYAKHTRSQETYRQEPVDVLIVEGILVLEDERL
CCCCCHHHHHHHHHHHCCCCEECCCHHHHHHHHCCHHHHHHCCCEEEEECCEEEECCHHH
RDLMDIKIFVDTDDDVRIIRRIRRDIEERGRTLDSVITQYLEAVKPMYHQFIEPTKRYAD
HHHEEEEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIIPEGVSNTVGVDIITTKIASILND
EECCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKTLIIGVTGGSASGKTSVSHAILETFSNERIAMIEHDSYYKDQSHLTFEERTKTNYDH
CCCEEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHCCCCCC
PLAFDTDYLIAQLKELQYGRAVDIPIYDYAKHTRSQETYRQEPVDVLIVEGILVLEDERL
CCCCCHHHHHHHHHHHCCCCEECCCHHHHHHHHCCHHHHHHCCCEEEEECCEEEECCHHH
RDLMDIKIFVDTDDDVRIIRRIRRDIEERGRTLDSVITQYLEAVKPMYHQFIEPTKRYAD
HHHEEEEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIIPEGVSNTVGVDIITTKIASILND
EECCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]