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The map label for this gene is isaA [H]

Identifier: 125623614

GI number: 125623614

Start: 749121

End: 749720

Strand: Direct

Name: isaA [H]

Synonym: llmg_0760

Alternate gene names: 125623614

Gene position: 749121-749720 (Clockwise)

Preceding gene: 125623612

Following gene: 125623616

Centisome position: 29.62

GC content: 40.17

Gene sequence:

>600_bases
ATGAAATTAAGTAAAGTTGCTATTTCAACTGGATTAGTTGCATCATTCATGTTTATTGGGGGCGGAATCGCTCATGCGGA
TACACCTAAATCAACTCATGAAGTTGCTATTGAAGTTATTAACGGAAATTACGGTAATGGAGACGCTCGTGTCACTAACC
TTAAAACAAAAGGTTTTGATGTAAAAGCAATCCAAACAGAAGTTAATAACATTCTGACAGGAACAACAACACAAGTTTCT
GCTACAGCTAAGACTGCTGAAGAACAACCTACTAAAGTTACATCAGCTGCACCTGCTCAAGCAGCAGAAAGTGTTTCTGG
TGGGCTTAATATGAGCCAAACTTCTGGACAAATTGACATCCAAGCTCTTGCTAATTATATGGCATCGAATACAGCTAATG
CAGCGGGCTATTCTGCTAGTGAATGGGCTTATATCATCACTCATGAATCAAATGGGATGGCTGATAGTGTGAATTCAAGT
TCAGGTGCTTACGGTGCCTTCCAATTATTGGGTCATGGTGAATACGCAGGTATGACTCTGGCTGAACAAATTGCAATGGC
AAGCAAACTTCCAGCAGGTAGTTGGGTAGTTTATAACTAA

Upstream 100 bases:

>100_bases
GACTTTATGATGTGTATGGGAAGTAACCATGATGATAGAAGATAGACTGGGCTGATCAAGTCCTATGGAATGTTCTTAGT
GGCGAAATCGAAAGGTCTAA

Downstream 100 bases:

>100_bases
GCATTGATAAAATTCGTCTTTTAATATTTGAACAATAAATCAAACTTAGCGGCTCATAACAATCATTGTCAAGTTAATTG
GTAATCGATTGAGTATAAAA

Product: putative transglycosylase

Products: NA

Alternate protein names: Immunodominant staphylococcal antigen A [H]

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MKLSKVAISTGLVASFMFIGGGIAHADTPKSTHEVAIEVINGNYGNGDARVTNLKTKGFDVKAIQTEVNNILTGTTTQVS
ATAKTAEEQPTKVTSAAPAQAAESVSGGLNMSQTSGQIDIQALANYMASNTANAAGYSASEWAYIITHESNGMADSVNSS
SGAYGAFQLLGHGEYAGMTLAEQIAMASKLPAGSWVVYN

Sequences:

>Translated_199_residues
MKLSKVAISTGLVASFMFIGGGIAHADTPKSTHEVAIEVINGNYGNGDARVTNLKTKGFDVKAIQTEVNNILTGTTTQVS
ATAKTAEEQPTKVTSAAPAQAAESVSGGLNMSQTSGQIDIQALANYMASNTANAAGYSASEWAYIITHESNGMADSVNSS
SGAYGAFQLLGHGEYAGMTLAEQIAMASKLPAGSWVVYN
>Mature_199_residues
MKLSKVAISTGLVASFMFIGGGIAHADTPKSTHEVAIEVINGNYGNGDARVTNLKTKGFDVKAIQTEVNNILTGTTTQVS
ATAKTAEEQPTKVTSAAPAQAAESVSGGLNMSQTSGQIDIQALANYMASNTANAAGYSASEWAYIITHESNGMADSVNSS
SGAYGAFQLLGHGEYAGMTLAEQIAMASKLPAGSWVVYN

Specific function: Is able to cleave peptidoglycan [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transglycosylase family. IsaA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010618 [H]

Pfam domain/function: PF06737 Transglycosylas [H]

EC number: NA

Molecular weight: Translated: 20474; Mature: 20474

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSKVAISTGLVASFMFIGGGIAHADTPKSTHEVAIEVINGNYGNGDARVTNLKTKGFD
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEEECCCCE
VKAIQTEVNNILTGTTTQVSATAKTAEEQPTKVTSAAPAQAAESVSGGLNMSQTSGQIDI
EEHHHHHHHHHCCCCCCEEEHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCEEH
QALANYMASNTANAAGYSASEWAYIITHESNGMADSVNSSSGAYGAFQLLGHGEYAGMTL
HHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEEECCCCCCHHH
AEQIAMASKLPAGSWVVYN
HHHHHHHHCCCCCCEEEEC
>Mature Secondary Structure
MKLSKVAISTGLVASFMFIGGGIAHADTPKSTHEVAIEVINGNYGNGDARVTNLKTKGFD
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEEECCCCE
VKAIQTEVNNILTGTTTQVSATAKTAEEQPTKVTSAAPAQAAESVSGGLNMSQTSGQIDI
EEHHHHHHHHHCCCCCCEEEHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCEEH
QALANYMASNTANAAGYSASEWAYIITHESNGMADSVNSSSGAYGAFQLLGHGEYAGMTL
HHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEEECCCCCCHHH
AEQIAMASKLPAGSWVVYN
HHHHHHHHCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA