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The map label for this gene is agl [H]

Identifier: 125623598

GI number: 125623598

Start: 728467

End: 730092

Strand: Direct

Name: agl [H]

Synonym: llmg_0744

Alternate gene names: 125623598

Gene position: 728467-730092 (Clockwise)

Preceding gene: 125623597

Following gene: 125623599

Centisome position: 28.8

GC content: 37.39

Gene sequence:

>1626_bases
ATGAAAAAAACAAAAACAAATGATTTTCACAAGATGGTCGGTTATCAGATTTATCCAAAATCTTTCAAAGATAGCAATGG
CGATGGGCTGGGTGATATTAAGGGAATAATTGAAAAATTACCTTATTTGCGAGAACTGGGTGTTGATTTTCTCTGGATTA
ATCCCATTTATAAGAGTCCACAAATTGATGGGGGCTACGATATTTCTGATTTTTATGCCATTGATGAAATGTTTGGAACG
CTTGATGATTTCCAAACATTGTTAAAAGAAGCGCATGATTTAGACCTGAAAATAATGTTGGACTTGGTGGTTAACCACAC
CTCAGACCAGCATCCTTGGTTCATAGAAAGTCAAAAATCAAAAGATAATCCTTATCGTGATTACTATTTGTGGGAAGATG
CGAGTCCTAATCAGATGCCAAATGAGTGGATTTCCTTTTTTGGCGGCTCAACTTGGGCCTATGATGAAAAAACAAAACAA
GCCTATTTTCACGTATTTGCCAAGGAGCAGCCTGATTTGAACTGGAAAAATCCTAAAGTTTGTCAGGAAATTTACAAAAT
GATTCGTTGGTGGTTGGATTTGGGAATAGATGGATTTAGGTTAGACGCCATTTCTCATATTCAAAAGATGCCTTGGTCTT
ATAAAATTAAATCTTGGAAGGGTAATGGTCCATGGATTCCTTTTATGAATGTTTCTGGAATTGAAACTTACATGGCTGAG
TTAAAAGCGATATTTGATGAATATGGGGCTTTGACAGTTGGTGAGGCTTCGGGTGTACAATCCACAGAAGCGCCAGACTG
GACTGATGAATCTGGCTATATCAATATGATTTTTGAATTAGAGCATAACGTCAGAAAAGCCAATGACCAGAGTCAAGGAG
ATACCTATGGCTACAAAAAAGTCATCATGCGTTGGCAAGAAGATTTGCTTTCACGAGGATGGAATGCTTTGTATATCGAA
AATCATGACCAACCGCGAAGTATTGATACTTTTGGCAATGGCTCAATAGAATCAGCCAAGGCACTAGCGGTATCTTACAT
GCTTTTACGTGGGACGCCTTTCATTTATCAAGGACAGGAATTCGGCATGAGCAATTTCCCATTTACTGACAGTAAGCAAT
TGAGGTCTGATGAGATAATTAAACAATATGACCAATTACTGACAAAATTATCAGAAAAAAAGGCTTTAGAAGAGGTCAGT
AAAAACAGTCGCGAACATTCTCGGACGCCTCTGCAGTGGAATGATTCTGAAAATGCCGGATTTACGACGGGACATCCTTG
GATGGAAATAAATCCTAACTTTTCTGAAATTAATCGTCAAACCAACCAAGAACTGATTGAACTTTATAAAAACTTAATTG
AATTACGGCATAAAGAAACTGCAATTTCGGATGGCTCTATCCATTTTCATTTCAAACGGCACCCGCAAGTTTTGGTTTAC
GAGCGAGATGAATTTTTAATTATTGTCAATTTGGCTGATAAAAAAGCACATTTGGATTTCTCAAAGATTGCCAATTTTGC
TGATGGGGAAACTATTAATTATCAACAAGTTCTGGGCAGCTCAAATAGTCCATTTCAAGAAAAGATGGTTCTGTTAGCCT
GGGAATATCGGGTTTATAAAAAATAG

Upstream 100 bases:

>100_bases
ATTGACTGATGGAAAATTGACAATTCCAGCTTACAGTACAGTTATTTTGAAAAAATAAATAAGTTCAGTTTAGGGACTTT
AAAAATGAAAATGTAAAACT

Downstream 100 bases:

>100_bases
AAGGTGAGAACAAAAAAAGATTATGAAACAAATCAAAAGAATTATGGGCATTGACCCTTGGAAAATCACATCAAATCAGA
TTGAAAAAGAAGACCGACGG

Product: alpha-glucosidase

Products: NA

Alternate protein names: Dextrin 6-alpha-D-glucanohydrolase; Oligosaccharide alpha-1,6-glucosidase; Sucrase-isomaltase; Isomaltase [H]

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MKKTKTNDFHKMVGYQIYPKSFKDSNGDGLGDIKGIIEKLPYLRELGVDFLWINPIYKSPQIDGGYDISDFYAIDEMFGT
LDDFQTLLKEAHDLDLKIMLDLVVNHTSDQHPWFIESQKSKDNPYRDYYLWEDASPNQMPNEWISFFGGSTWAYDEKTKQ
AYFHVFAKEQPDLNWKNPKVCQEIYKMIRWWLDLGIDGFRLDAISHIQKMPWSYKIKSWKGNGPWIPFMNVSGIETYMAE
LKAIFDEYGALTVGEASGVQSTEAPDWTDESGYINMIFELEHNVRKANDQSQGDTYGYKKVIMRWQEDLLSRGWNALYIE
NHDQPRSIDTFGNGSIESAKALAVSYMLLRGTPFIYQGQEFGMSNFPFTDSKQLRSDEIIKQYDQLLTKLSEKKALEEVS
KNSREHSRTPLQWNDSENAGFTTGHPWMEINPNFSEINRQTNQELIELYKNLIELRHKETAISDGSIHFHFKRHPQVLVY
ERDEFLIIVNLADKKAHLDFSKIANFADGETINYQQVLGSSNSPFQEKMVLLAWEYRVYKK

Sequences:

>Translated_541_residues
MKKTKTNDFHKMVGYQIYPKSFKDSNGDGLGDIKGIIEKLPYLRELGVDFLWINPIYKSPQIDGGYDISDFYAIDEMFGT
LDDFQTLLKEAHDLDLKIMLDLVVNHTSDQHPWFIESQKSKDNPYRDYYLWEDASPNQMPNEWISFFGGSTWAYDEKTKQ
AYFHVFAKEQPDLNWKNPKVCQEIYKMIRWWLDLGIDGFRLDAISHIQKMPWSYKIKSWKGNGPWIPFMNVSGIETYMAE
LKAIFDEYGALTVGEASGVQSTEAPDWTDESGYINMIFELEHNVRKANDQSQGDTYGYKKVIMRWQEDLLSRGWNALYIE
NHDQPRSIDTFGNGSIESAKALAVSYMLLRGTPFIYQGQEFGMSNFPFTDSKQLRSDEIIKQYDQLLTKLSEKKALEEVS
KNSREHSRTPLQWNDSENAGFTTGHPWMEINPNFSEINRQTNQELIELYKNLIELRHKETAISDGSIHFHFKRHPQVLVY
ERDEFLIIVNLADKKAHLDFSKIANFADGETINYQQVLGSSNSPFQEKMVLLAWEYRVYKK
>Mature_541_residues
MKKTKTNDFHKMVGYQIYPKSFKDSNGDGLGDIKGIIEKLPYLRELGVDFLWINPIYKSPQIDGGYDISDFYAIDEMFGT
LDDFQTLLKEAHDLDLKIMLDLVVNHTSDQHPWFIESQKSKDNPYRDYYLWEDASPNQMPNEWISFFGGSTWAYDEKTKQ
AYFHVFAKEQPDLNWKNPKVCQEIYKMIRWWLDLGIDGFRLDAISHIQKMPWSYKIKSWKGNGPWIPFMNVSGIETYMAE
LKAIFDEYGALTVGEASGVQSTEAPDWTDESGYINMIFELEHNVRKANDQSQGDTYGYKKVIMRWQEDLLSRGWNALYIE
NHDQPRSIDTFGNGSIESAKALAVSYMLLRGTPFIYQGQEFGMSNFPFTDSKQLRSDEIIKQYDQLLTKLSEKKALEEVS
KNSREHSRTPLQWNDSENAGFTTGHPWMEINPNFSEINRQTNQELIELYKNLIELRHKETAISDGSIHFHFKRHPQVLVY
ERDEFLIIVNLADKKAHLDFSKIANFADGETINYQQVLGSSNSPFQEKMVLLAWEYRVYKK

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=511, Percent_Identity=30.5283757338552, Blast_Score=233, Evalue=5e-61,
Organism=Escherichia coli, GI1790687, Length=499, Percent_Identity=37.2745490981964, Blast_Score=341, Evalue=6e-95,
Organism=Escherichia coli, GI1786604, Length=367, Percent_Identity=24.7956403269755, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI32565753, Length=197, Percent_Identity=31.4720812182741, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI25147709, Length=212, Percent_Identity=27.3584905660377, Blast_Score=79, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6322245, Length=573, Percent_Identity=33.8568935427574, Blast_Score=289, Evalue=9e-79,
Organism=Saccharomyces cerevisiae, GI6321726, Length=504, Percent_Identity=36.1111111111111, Blast_Score=281, Evalue=1e-76,
Organism=Saccharomyces cerevisiae, GI6324416, Length=499, Percent_Identity=35.8717434869739, Blast_Score=275, Evalue=2e-74,
Organism=Saccharomyces cerevisiae, GI6322241, Length=501, Percent_Identity=35.3293413173653, Blast_Score=273, Evalue=4e-74,
Organism=Saccharomyces cerevisiae, GI6322021, Length=501, Percent_Identity=35.3293413173653, Blast_Score=273, Evalue=4e-74,
Organism=Saccharomyces cerevisiae, GI6319776, Length=574, Percent_Identity=33.1010452961672, Blast_Score=257, Evalue=4e-69,
Organism=Saccharomyces cerevisiae, GI6321731, Length=574, Percent_Identity=33.1010452961672, Blast_Score=257, Evalue=4e-69,
Organism=Drosophila melanogaster, GI24583747, Length=552, Percent_Identity=33.1521739130435, Blast_Score=267, Evalue=2e-71,
Organism=Drosophila melanogaster, GI24583749, Length=553, Percent_Identity=33.0922242314647, Blast_Score=266, Evalue=3e-71,
Organism=Drosophila melanogaster, GI24586597, Length=528, Percent_Identity=32.1969696969697, Blast_Score=263, Evalue=3e-70,
Organism=Drosophila melanogaster, GI24586599, Length=562, Percent_Identity=31.1387900355872, Blast_Score=261, Evalue=6e-70,
Organism=Drosophila melanogaster, GI221330053, Length=508, Percent_Identity=32.6771653543307, Blast_Score=259, Evalue=3e-69,
Organism=Drosophila melanogaster, GI24586589, Length=559, Percent_Identity=31.484794275492, Blast_Score=254, Evalue=1e-67,
Organism=Drosophila melanogaster, GI24583745, Length=532, Percent_Identity=31.5789473684211, Blast_Score=248, Evalue=9e-66,
Organism=Drosophila melanogaster, GI24586591, Length=564, Percent_Identity=32.4468085106383, Blast_Score=247, Evalue=2e-65,
Organism=Drosophila melanogaster, GI24586587, Length=568, Percent_Identity=30.4577464788732, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI24586593, Length=200, Percent_Identity=48.5, Blast_Score=210, Evalue=2e-54,
Organism=Drosophila melanogaster, GI45549022, Length=199, Percent_Identity=45.7286432160804, Blast_Score=197, Evalue=1e-50,
Organism=Drosophila melanogaster, GI281360393, Length=152, Percent_Identity=43.421052631579, Blast_Score=139, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.10 [H]

Molecular weight: Translated: 63133; Mature: 63133

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTKTNDFHKMVGYQIYPKSFKDSNGDGLGDIKGIIEKLPYLRELGVDFLWINPIYKSP
CCCCCCCHHHHHHCCEECCCCCCCCCCCCCHHHHHHHHHCCHHHHCCCCEEEECCCCCCC
QIDGGYDISDFYAIDEMFGTLDDFQTLLKEAHDLDLKIMLDLVVNHTSDQHPWFIESQKS
CCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHEEEEHHHCCCCCCCCEEEECCCC
KDNPYRDYYLWEDASPNQMPNEWISFFGGSTWAYDEKTKQAYFHVFAKEQPDLNWKNPKV
CCCCCCCEEEECCCCCCCCCHHHHHHHCCCEEECCHHHHHHHEEEEECCCCCCCCCCHHH
CQEIYKMIRWWLDLGIDGFRLDAISHIQKMPWSYKIKSWKGNGPWIPFMNVSGIETYMAE
HHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCCCEEEEEECCCCCEEEEECCCHHHHHHHH
LKAIFDEYGALTVGEASGVQSTEAPDWTDESGYINMIFELEHNVRKANDQSQGDTYGYKK
HHHHHHHHCCEEECCCCCCCCCCCCCCCCCCCEEEEEEEECHHHHHCCCCCCCCHHHHHH
VIMRWQEDLLSRGWNALYIENHDQPRSIDTFGNGSIESAKALAVSYMLLRGTPFIYQGQE
HHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEECCHH
FGMSNFPFTDSKQLRSDEIIKQYDQLLTKLSEKKALEEVSKNSREHSRTPLQWNDSENAG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCC
FTTGHPWMEINPNFSEINRQTNQELIELYKNLIELRHKETAISDGSIHFHFKRHPQVLVY
CCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEE
ERDEFLIIVNLADKKAHLDFSKIANFADGETINYQQVLGSSNSPFQEKMVLLAWEYRVYK
ECCCEEEEEEECCCCCCCCHHHHCCCCCCCCCCHHHHHCCCCCCHHHCEEEEEEEEEEEC
K
C
>Mature Secondary Structure
MKKTKTNDFHKMVGYQIYPKSFKDSNGDGLGDIKGIIEKLPYLRELGVDFLWINPIYKSP
CCCCCCCHHHHHHCCEECCCCCCCCCCCCCHHHHHHHHHCCHHHHCCCCEEEECCCCCCC
QIDGGYDISDFYAIDEMFGTLDDFQTLLKEAHDLDLKIMLDLVVNHTSDQHPWFIESQKS
CCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHEEEEHHHCCCCCCCCEEEECCCC
KDNPYRDYYLWEDASPNQMPNEWISFFGGSTWAYDEKTKQAYFHVFAKEQPDLNWKNPKV
CCCCCCCEEEECCCCCCCCCHHHHHHHCCCEEECCHHHHHHHEEEEECCCCCCCCCCHHH
CQEIYKMIRWWLDLGIDGFRLDAISHIQKMPWSYKIKSWKGNGPWIPFMNVSGIETYMAE
HHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCCCEEEEEECCCCCEEEEECCCHHHHHHHH
LKAIFDEYGALTVGEASGVQSTEAPDWTDESGYINMIFELEHNVRKANDQSQGDTYGYKK
HHHHHHHHCCEEECCCCCCCCCCCCCCCCCCCEEEEEEEECHHHHHCCCCCCCCHHHHHH
VIMRWQEDLLSRGWNALYIENHDQPRSIDTFGNGSIESAKALAVSYMLLRGTPFIYQGQE
HHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEECCHH
FGMSNFPFTDSKQLRSDEIIKQYDQLLTKLSEKKALEEVSKNSREHSRTPLQWNDSENAG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCC
FTTGHPWMEINPNFSEINRQTNQELIELYKNLIELRHKETAISDGSIHFHFKRHPQVLVY
CCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEE
ERDEFLIIVNLADKKAHLDFSKIANFADGETINYQQVLGSSNSPFQEKMVLLAWEYRVYK
ECCCEEEEEEECCCCCCCCHHHHCCCCCCCCCCHHHHHCCCCCCHHHCEEEEEEEEEEEC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1761534 [H]