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The map label for this gene is msrR [H]

Identifier: 125623588

GI number: 125623588

Start: 714312

End: 715703

Strand: Direct

Name: msrR [H]

Synonym: llmg_0733

Alternate gene names: 125623588

Gene position: 714312-715703 (Clockwise)

Preceding gene: 125623587

Following gene: 125623589

Centisome position: 28.24

GC content: 36.14

Gene sequence:

>1392_bases
ATGACAATGAATGAAAAAAAGTATAAACGCTTAGAATATTTGAGACATAATATCGATTATCTCACAATTAGAGAGCGTCA
AGAGTACTATGAGTTACTCAATGAACTGAAAAAAGAAGGAAATTATTCTGAATCTGAAGAATTTGAAGAATATACAGAAC
CAGAATATTCCGATTATGAATCAGAAAATTTTCAACAAAGAGATTTGGAATCACCCTCTAATAACTACAATACTAATAGA
AGAAATACACGAGAAAGTAGCCCAAGCCCAGAAAAAAATAGAAATAAAATTTCTACAGGCAACAAAGGTTCCAAAAAGGT
GAAATCTGGTAAGAAAAAGAAGCGACATTGGTTGAGAACAATATTTGGAATTATTATCTTGATTATTGTGCTTATGGTTG
GTTTCTTTGTGTACGGCTATCAACGTGGAGTCAAGCATGAAGGAAGTCCTGCAAAACAAGAAAAATTTACAAGTTTGAAA
AACTCAGATGGTTCAGTAAATATTTTGTTACTTGGGGCTGACCAAAGGCCTTGGCAATCTTCTGGTGTTGCTCATACGGA
TAGTATTATGGTTTTACATGTTAATGGTAAAGACCATAAGATACAAATTGTCAGCTTTATGCGTGACACCCTTGTCAATA
TTCCTGATGTAGGTTCAAGTGATAGTCCAGATTCAAAAATTAACTCTGCCTTCACAATTGGAGAACAATATAACAAACAA
GGTGTAAACCTGATGAGCGAGACATTGAAGAAAAATTTTGGTATTAATTGCCAATATTACGCGGTAGTAGATTTCTCAAG
CTTTGCGACAATTATTGATTCTTTATTCCCGACAGGCCTGAAAATTGATGCAAAATTCTCAACGGTAAATGGTGAAACGC
TATCAGCTGTACCTGTACCCGATGACCTTGCTGCAACGGAAGGGAAAACTTCAAGTGATAAAGACTTGACTGCTGAAGAG
GCTGCCGAATTGGGTTATCCTGATGGTGGTGGTACATTTATGATGATTAAACCGGGAACTCAAAAGATGGATGGTCGCAT
GTTGTTAAACTATGCTCGTTTCCGTCATGATGATGAGGGAGATTATGGGCGTGTTAAGCGTCAACAACAAGTTTTAGAAA
CAGTAATGTCTAAAATGAAAAATCCACTTGCTTTATTCACTGCATCAAGTGCTCTTGGAACGACAAGAGCCGTCACAATG
ACCAATATTCCTAATTCTTTCTTCTTAACAAAGGGAATTACAACCTTGTTGGATATGAAAAATGGAATTAACTCAACAAC
TATTCCAGCAGATAATGACTGGGAAAACGCTTATGACATGTATGGAGGTTTAGGACTTTCAATTGATATGACAAAATACA
AAGCGAAAGCTCAAGAACTCCTTGGCCAATAA

Upstream 100 bases:

>100_bases
AAAGCCAAAAAACTCATGTAAAATGAGTTTTTTTATATTTTTCTGTATTATAAATCCTTTGCAAGTTTTTGCAGGAATTA
TCAAACTTTGATATAATAAT

Downstream 100 bases:

>100_bases
TAAAAAGTTACTGACAGTTTCTTGTCAGTAACTTTTTTATGACTAGTCTAATAGATAAGGAGTAAGTAAATATAGACAAA
TCCAGTAGTAAAAGAGGATT

Product: cell envelope-related transcriptional attenuator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MTMNEKKYKRLEYLRHNIDYLTIRERQEYYELLNELKKEGNYSESEEFEEYTEPEYSDYESENFQQRDLESPSNNYNTNR
RNTRESSPSPEKNRNKISTGNKGSKKVKSGKKKKRHWLRTIFGIIILIIVLMVGFFVYGYQRGVKHEGSPAKQEKFTSLK
NSDGSVNILLLGADQRPWQSSGVAHTDSIMVLHVNGKDHKIQIVSFMRDTLVNIPDVGSSDSPDSKINSAFTIGEQYNKQ
GVNLMSETLKKNFGINCQYYAVVDFSSFATIIDSLFPTGLKIDAKFSTVNGETLSAVPVPDDLAATEGKTSSDKDLTAEE
AAELGYPDGGGTFMMIKPGTQKMDGRMLLNYARFRHDDEGDYGRVKRQQQVLETVMSKMKNPLALFTASSALGTTRAVTM
TNIPNSFFLTKGITTLLDMKNGINSTTIPADNDWENAYDMYGGLGLSIDMTKYKAKAQELLGQ

Sequences:

>Translated_463_residues
MTMNEKKYKRLEYLRHNIDYLTIRERQEYYELLNELKKEGNYSESEEFEEYTEPEYSDYESENFQQRDLESPSNNYNTNR
RNTRESSPSPEKNRNKISTGNKGSKKVKSGKKKKRHWLRTIFGIIILIIVLMVGFFVYGYQRGVKHEGSPAKQEKFTSLK
NSDGSVNILLLGADQRPWQSSGVAHTDSIMVLHVNGKDHKIQIVSFMRDTLVNIPDVGSSDSPDSKINSAFTIGEQYNKQ
GVNLMSETLKKNFGINCQYYAVVDFSSFATIIDSLFPTGLKIDAKFSTVNGETLSAVPVPDDLAATEGKTSSDKDLTAEE
AAELGYPDGGGTFMMIKPGTQKMDGRMLLNYARFRHDDEGDYGRVKRQQQVLETVMSKMKNPLALFTASSALGTTRAVTM
TNIPNSFFLTKGITTLLDMKNGINSTTIPADNDWENAYDMYGGLGLSIDMTKYKAKAQELLGQ
>Mature_462_residues
TMNEKKYKRLEYLRHNIDYLTIRERQEYYELLNELKKEGNYSESEEFEEYTEPEYSDYESENFQQRDLESPSNNYNTNRR
NTRESSPSPEKNRNKISTGNKGSKKVKSGKKKKRHWLRTIFGIIILIIVLMVGFFVYGYQRGVKHEGSPAKQEKFTSLKN
SDGSVNILLLGADQRPWQSSGVAHTDSIMVLHVNGKDHKIQIVSFMRDTLVNIPDVGSSDSPDSKINSAFTIGEQYNKQG
VNLMSETLKKNFGINCQYYAVVDFSSFATIIDSLFPTGLKIDAKFSTVNGETLSAVPVPDDLAATEGKTSSDKDLTAEEA
AELGYPDGGGTFMMIKPGTQKMDGRMLLNYARFRHDDEGDYGRVKRQQQVLETVMSKMKNPLALFTASSALGTTRAVTMT
NIPNSFFLTKGITTLLDMKNGINSTTIPADNDWENAYDMYGGLGLSIDMTKYKAKAQELLGQ

Specific function: Involved in sarA attenuation. Affects resistance to oxacillin and teicoplanin, as well as the synthesis of virulence factors [H]

COG id: COG1316

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LytR/CpsA/Psr regulatory protein family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004474 [H]

Pfam domain/function: PF03816 LytR_cpsA_psr [H]

EC number: NA

Molecular weight: Translated: 52164; Mature: 52033

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMNEKKYKRLEYLRHNIDYLTIRERQEYYELLNELKKEGNYSESEEFEEYTEPEYSDYE
CCCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCC
SENFQQRDLESPSNNYNTNRRNTRESSPSPEKNRNKISTGNKGSKKVKSGKKKKRHWLRT
CCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHH
IFGIIILIIVLMVGFFVYGYQRGVKHEGSPAKQEKFTSLKNSDGSVNILLLGADQRPWQS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCC
SGVAHTDSIMVLHVNGKDHKIQIVSFMRDTLVNIPDVGSSDSPDSKINSAFTIGEQYNKQ
CCCCCCCCEEEEEECCCCCEEEHHHHHHHHHCCCCCCCCCCCCCHHHHHHEEECHHHCHH
GVNLMSETLKKNFGINCQYYAVVDFSSFATIIDSLFPTGLKIDAKFSTVNGETLSAVPVP
HHHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHCCCCEEEEEEEEECCCCEEEECCCC
DDLAATEGKTSSDKDLTAEEAAELGYPDGGGTFMMIKPGTQKMDGRMLLNYARFRHDDEG
CCHHCCCCCCCCCCCCCHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCC
DYGRVKRQQQVLETVMSKMKNPLALFTASSALGTTRAVTMTNIPNSFFLTKGITTLLDMK
CHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHH
NGINSTTIPADNDWENAYDMYGGLGLSIDMTKYKAKAQELLGQ
CCCCCCCCCCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHCC
>Mature Secondary Structure 
TMNEKKYKRLEYLRHNIDYLTIRERQEYYELLNELKKEGNYSESEEFEEYTEPEYSDYE
CCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCC
SENFQQRDLESPSNNYNTNRRNTRESSPSPEKNRNKISTGNKGSKKVKSGKKKKRHWLRT
CCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHH
IFGIIILIIVLMVGFFVYGYQRGVKHEGSPAKQEKFTSLKNSDGSVNILLLGADQRPWQS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCC
SGVAHTDSIMVLHVNGKDHKIQIVSFMRDTLVNIPDVGSSDSPDSKINSAFTIGEQYNKQ
CCCCCCCCEEEEEECCCCCEEEHHHHHHHHHCCCCCCCCCCCCCHHHHHHEEECHHHCHH
GVNLMSETLKKNFGINCQYYAVVDFSSFATIIDSLFPTGLKIDAKFSTVNGETLSAVPVP
HHHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHCCCCEEEEEEEEECCCCEEEECCCC
DDLAATEGKTSSDKDLTAEEAAELGYPDGGGTFMMIKPGTQKMDGRMLLNYARFRHDDEG
CCHHCCCCCCCCCCCCCHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCC
DYGRVKRQQQVLETVMSKMKNPLALFTASSALGTTRAVTMTNIPNSFFLTKGITTLLDMK
CHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHH
NGINSTTIPADNDWENAYDMYGGLGLSIDMTKYKAKAQELLGQ
CCCCCCCCCCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12878519 [H]