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The map label for this gene is hsdS [C]

Identifier: 125623519

GI number: 125623519

Start: 655644

End: 656894

Strand: Direct

Name: hsdS [C]

Synonym: llmg_0660

Alternate gene names: 125623519

Gene position: 655644-656894 (Clockwise)

Preceding gene: 125623518

Following gene: 125623520

Centisome position: 25.92

GC content: 31.02

Gene sequence:

>1251_bases
ATGATGAGTATAAAAAGTCCACAATTAAGGTTTGAAGGTTTTACGGATGATTGGGAACAGCGTAAGTTAGGGGAACTTTC
TCAAAAAATATCAGTAGGCATTGCTACATCTTCGAGTAAATATTTTAGTTCTCAAGATCAAGGAGTTCCATTTATAAAAA
ATCAGGATATTAAAGAGAATAGAATAAATACCAAAAATTTAGAATATATTTCTAAAGAGTTTGATAATAAAAATAAAAAT
AAAAGAGTGAAGCAAGGCGACATAATTACAGCTAGAACTGGTTATCCAGGTCTAAGTGCTGTAGTACCCAAAGAGTTAGA
AGGGGCGCAAACGTTCACCACACTAATTACTAGACCAATATCTGAAATGATTTTATCTGAATATATTTCAATATTTATAA
ATTCTCCATATGGTATGAAACAAATAAGTGGTATGGAAGCTGGCGGAGCTCAAAAAAATGTAAATGCTGGTATAGTGCAA
AATTTACTTATACCGTTACCTTCTTTGGATGAACAAAAAAAAATATCTAATTTTATTTTAAAGTTAGATGACACTATCGC
TCTTAATCAGCGTAAGATAGATTTGTTGAAAGAACAGAAAAAAGGCTACTTGCAAAAAATGTTCCCTAAAAATGGTGCCA
AAGTTCCTGAATTGCGATTTGCGGGGTTTGTTGACGATTGGGAACAGCGTAAGTTGTCCGATTTAATGACTTTTTCAAAT
GGAATTAATGCTCCTAAAGAAAATTATGGAAAAGGAACTAAAATGATTAGTGTCATGGATATACTAAATCCTTTACCTAT
AAAGTATGACAATATATTAAATTCTGTATCCGTTGATAAAAAAATCGAAGATAAAAACAAAGTTGAAAACGGTGATTTAA
TATTTGTTCGTTCTTCAGAGATTGTTGAAGAAGTTGGATGGGCAAAAGCTTATAAAGAAGCTCGCTACGCTTTGTATAGT
GGTTTTGCTATTAGAGGAAAACGAATCAGTTCTTATAATGCGTATTTTATTGAATTAACTCTAAATTATGCTAATAGAAA
AGAAATTAAACGAAGAGCTGGTGGCAGTACTCGATTTAATGTTAGCCAAGAAATTTTAAATTCTTTGACTGTTTTAACTC
CTTCAATTTCTGAGCAAAATCAAATAGATTTATTTTTTACTAAAATAGACGACACTATCACTCTTCATCAACGTAAGTTA
GATTTGTTGAAAGAACAGAAAAAAGGCTTTTTACAAAAGATGTTCGTTTAG

Upstream 100 bases:

>100_bases
CAACAAGAGCAAGTGCTCTTATCGTTGATTAACGATTTTTCAGAAAGTGAAGAGAATCAAGCCTTGATTGAATCGATGCG
TCTTCTTTTGAGAGGCGGTC

Downstream 100 bases:

>100_bases
GGTCTAAAATTATAAATTAGATAATACATTAGAAGCTGGAGACGAGATTGTCTAGATAATGTGCGAGATAAAATTTTTAG
CAGGTTATCATACATAAGAC

Product: specificity determinant HsdS

Products: NA

Alternate protein names: S.MjaXIP; Type I restriction enzyme MjaXIP specificity protein; S protein [H]

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MMSIKSPQLRFEGFTDDWEQRKLGELSQKISVGIATSSSKYFSSQDQGVPFIKNQDIKENRINTKNLEYISKEFDNKNKN
KRVKQGDIITARTGYPGLSAVVPKELEGAQTFTTLITRPISEMILSEYISIFINSPYGMKQISGMEAGGAQKNVNAGIVQ
NLLIPLPSLDEQKKISNFILKLDDTIALNQRKIDLLKEQKKGYLQKMFPKNGAKVPELRFAGFVDDWEQRKLSDLMTFSN
GINAPKENYGKGTKMISVMDILNPLPIKYDNILNSVSVDKKIEDKNKVENGDLIFVRSSEIVEEVGWAKAYKEARYALYS
GFAIRGKRISSYNAYFIELTLNYANRKEIKRRAGGSTRFNVSQEILNSLTVLTPSISEQNQIDLFFTKIDDTITLHQRKL
DLLKEQKKGFLQKMFV

Sequences:

>Translated_416_residues
MMSIKSPQLRFEGFTDDWEQRKLGELSQKISVGIATSSSKYFSSQDQGVPFIKNQDIKENRINTKNLEYISKEFDNKNKN
KRVKQGDIITARTGYPGLSAVVPKELEGAQTFTTLITRPISEMILSEYISIFINSPYGMKQISGMEAGGAQKNVNAGIVQ
NLLIPLPSLDEQKKISNFILKLDDTIALNQRKIDLLKEQKKGYLQKMFPKNGAKVPELRFAGFVDDWEQRKLSDLMTFSN
GINAPKENYGKGTKMISVMDILNPLPIKYDNILNSVSVDKKIEDKNKVENGDLIFVRSSEIVEEVGWAKAYKEARYALYS
GFAIRGKRISSYNAYFIELTLNYANRKEIKRRAGGSTRFNVSQEILNSLTVLTPSISEQNQIDLFFTKIDDTITLHQRKL
DLLKEQKKGFLQKMFV
>Mature_416_residues
MMSIKSPQLRFEGFTDDWEQRKLGELSQKISVGIATSSSKYFSSQDQGVPFIKNQDIKENRINTKNLEYISKEFDNKNKN
KRVKQGDIITARTGYPGLSAVVPKELEGAQTFTTLITRPISEMILSEYISIFINSPYGMKQISGMEAGGAQKNVNAGIVQ
NLLIPLPSLDEQKKISNFILKLDDTIALNQRKIDLLKEQKKGYLQKMFPKNGAKVPELRFAGFVDDWEQRKLSDLMTFSN
GINAPKENYGKGTKMISVMDILNPLPIKYDNILNSVSVDKKIEDKNKVENGDLIFVRSSEIVEEVGWAKAYKEARYALYS
GFAIRGKRISSYNAYFIELTLNYANRKEIKRRAGGSTRFNVSQEILNSLTVLTPSISEQNQIDLFFTKIDDTITLHQRKL
DLLKEQKKGFLQKMFV

Specific function: The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. In the presence of the R subunit the complex can also act as an endonuclease, binding to

COG id: COG0732

COG function: function code V; Restriction endonuclease S subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I restriction system S methylase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000055 [H]

Pfam domain/function: PF01420 Methylase_S [H]

EC number: NA

Molecular weight: Translated: 47337; Mature: 47337

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSIKSPQLRFEGFTDDWEQRKLGELSQKISVGIATSSSKYFSSQDQGVPFIKNQDIKEN
CCCCCCCCEEECCCCCCHHHHHHHHHHHHHEEEEEECCCHHCCCCCCCCCCCCCCCCHHC
RINTKNLEYISKEFDNKNKNKRVKQGDIITARTGYPGLSAVVPKELEGAQTFTTLITRPI
CCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHCCHHHHHHHHHHHH
SEMILSEYISIFINSPYGMKQISGMEAGGAQKNVNAGIVQNLLIPLPSLDEQKKISNFIL
HHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHH
KLDDTIALNQRKIDLLKEQKKGYLQKMFPKNGAKVPELRFAGFVDDWEQRKLSDLMTFSN
CCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHC
GINAPKENYGKGTKMISVMDILNPLPIKYDNILNSVSVDKKIEDKNKVENGDLIFVRSSE
CCCCCHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHCCCCCCCEEEEECHH
IVEEVGWAKAYKEARYALYSGFAIRGKRISSYNAYFIELTLNYANRKEIKRRAGGSTRFN
HHHHHHHHHHHHHHHHHHHCCEEEECCEECCCCEEEEEEEECCCCHHHHHHHCCCCCEEC
VSQEILNSLTVLTPSISEQNQIDLFFTKIDDTITLHQRKLDLLKEQKKGFLQKMFV
HHHHHHHHHHHCCCCCCCCCCEEEEEEECCCEEEHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMSIKSPQLRFEGFTDDWEQRKLGELSQKISVGIATSSSKYFSSQDQGVPFIKNQDIKEN
CCCCCCCCEEECCCCCCHHHHHHHHHHHHHEEEEEECCCHHCCCCCCCCCCCCCCCCHHC
RINTKNLEYISKEFDNKNKNKRVKQGDIITARTGYPGLSAVVPKELEGAQTFTTLITRPI
CCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHCCHHHHHHHHHHHH
SEMILSEYISIFINSPYGMKQISGMEAGGAQKNVNAGIVQNLLIPLPSLDEQKKISNFIL
HHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHH
KLDDTIALNQRKIDLLKEQKKGYLQKMFPKNGAKVPELRFAGFVDDWEQRKLSDLMTFSN
CCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHC
GINAPKENYGKGTKMISVMDILNPLPIKYDNILNSVSVDKKIEDKNKVENGDLIFVRSSE
CCCCCHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHCCCCCCCEEEEECHH
IVEEVGWAKAYKEARYALYSGFAIRGKRISSYNAYFIELTLNYANRKEIKRRAGGSTRFN
HHHHHHHHHHHHHHHHHHHCCEEEECCEECCCCEEEEEEEECCCCHHHHHHHCCCCCEEC
VSQEILNSLTVLTPSISEQNQIDLFFTKIDDTITLHQRKLDLLKEQKKGFLQKMFV
HHHHHHHHHHHCCCCCCCCCCEEEEEEECCCEEEHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]