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The map label for this gene is pycA [H]

Identifier: 125623494

GI number: 125623494

Start: 624722

End: 628135

Strand: Direct

Name: pycA [H]

Synonym: llmg_0634

Alternate gene names: 125623494

Gene position: 624722-628135 (Clockwise)

Preceding gene: 125623493

Following gene: 125623495

Centisome position: 24.7

GC content: 39.54

Gene sequence:

>3414_bases
ATGAAAAAACTACTCGTCGCCAATCGTGGAGAAATCGCCGTTCGTGTCTTTCGTGCCTGTAATGAACTCGGACTTTCTAC
AGTAGCCGTCTATGCAAGAGAAGATGAATATTCCGTTCATCGCTTTAAAGCAGATGAATCTTACCTTATCGGTCAAGGTA
AAAAACCAATTGATGCTTATTTGGATATTGATGATATTATTCGTGTTGCTCTTGAATCAGGAGCAGATGCCATTCATCCC
GGTTATGGTCTTTTATCTGAAAATCTTGAATTTGCTACAAAAGTTCGAGCAGCAGGATTAGTTTTTGTCGGTCCTGAACT
TCATCATTTGGATATTTTCGGCGATAAAATCAAAGCAAAAGCCGCAGCTGATGAAGCTCAAGTTCCCGGAATTCCCGGAA
CAAATGGTGCAGTAGATATTGACGGAGCTCTTGAATTTGCTCAAACTTACGGATATCCAGTCATGATTAAGGCAGCATTG
GGCGGCGGCGGTCGTGGAATGCGTGTTGCGCGTAATGACGCTGAAATGCACGACGGATATGCTCGTGCGAAATCAGAAGC
TATCGGTGCCTTTGGTTCTGGAGAAATCTATGTTGAAAAATACATTGAAAATCCTAAGCATATTGAAGTTCAAATTCTTG
GGGATAGTCATGGAAATATTGTCCATTTGCACGAACGTGATTGCTCTGTCCAACGCCGAAATCAAAAAGTCATTGAAATT
GCTCCAGCCGTAGGACTCTCACCAGAGTTCCGTAATGAAATTTGTGAAGCAGCAGTTAAACTTTGTAAAAATGTTGGCTA
TGTTAATGCTGGGACGGTTGAATTTTTAGTCAAAGATGATAAGTTCTACTTTATCGAAGTCAACCCACGTGTTCAAGTTG
AACACACAATTACCGAGCTTATTACAGGTGTAGATATTGTTCAAGCACAAATTTTGATTGCTCAAGGCAAAGATTTACAT
ACAGAAATTGGTATCCCGGCACAAGCTGAAATACCACTTTTGGGCTCAGCCATTCAATGTCGTATTACTACAGAAGACCC
GCAAAATGGCTTCTTGCCAGATACAGGTAAAATCGATACCTACCGTTCACCAGGTGGTTTCGGCATTCGTTTGGACGTTG
GAAATGCCTATGCTGGTTATGAAGTGACTCCCTATTTTGACTCGCTTTTAGTAAAAGTTTGTACCTTTGCTAATGAATTT
AGCGATAGTGTACGTAAAATGGATCGTGTGCTTCATGAATTCCGTATTCGTGGGGTGAAAACTAATATTCCATTTTTGAT
TAATGTTATTGCCAATGAAAACTTTACGAGCGGACAAGCAACAACAACCTTTATTGACAATACTCCAAGTCTTTTCAATT
TCCCACGCTTACGTGACCGTGGAACAAAAACCTTACACTACTTATCAATGATTACAGTCAATGGTTTCCCAGGGATTGAA
AATACAGAAAAACGCCATTTTGAAGAACCTCGTCAACCTCTACTTAACATTGAAAAGAAAAAGACAGCTAAAAATATCTT
AGATGAACAAGGGGCTGATGCGGTAGTTGAATATGTGAAAAATACAAAAGAAGTATTATTGACAGATACAACTTTACGTG
ATGCTCACCAGTCTCTTCTTGCCACTCGTTTGCGTTTGCAAGATATGAAAGGAATTGCTCAAGCCATTGACCAAGGACTT
CCAGAACTTTTCTCAGCTGAAATGTGGGGTGGGGCAACCTTTGATGTCGCTTATCGTTTCTTGAATGAATCGCCTTGGTA
TCGTCTACGTAAATTACGTAAACTCATGCCAAATACCATGTTCCAAATGCTTTTCCGTGGTTCAAATGCAGTTGGATATC
AAAACTATCCTGATAATGTCATTGAAGAATTTATCCACGTAGCTGCACATGAAGGAATCGATGTCTTTCGTATCTTTGAT
AGCCTCAACTGGTTGCCACAAATGGAAAAATCAATCCAAGCAGTGCGTGATAATGGAAAAATTGCCGAAGCAACCATTTG
TTATACAGGAGATATCCTTGACCCAAGTCGACCAAAATATAATATCCAATACTACAAAGATTTGGCAAAAGAGTTAGAAG
CTACTGGGGCTCATATACTTGCCGTTAAAGATATGGCGGGCTTGTTGAAACCTCAAGCGGCATATCGCTTGATTTCAGAA
TTAAAAGATACGGTTGACTTACCAATTCACTTGCATACACATGATACTTCAGGAAATGGTATTATTACCTATTCTGGTGC
AACTCAAGCAGGAGTAGATATTATTGATGTGGCAACTGCCAGTCTTGCTGGTGGAACTTCTCAACCTTCAATGCAATCAA
TTTATTATGCCCTTGAACATGGTCCCCGTCATGCTTCAATTAATGTGAAAAATGCAGAGCAAATTGACCATTATTGGGAA
GATGTGCGTAAATATTATGCACCTTTTGAGGCAGGAATTACGAGCCCACAAACTGAAGTTTACATGCATGAAATGCCTGG
CGGACAATATACTAACTTGAAATCTCAAGCAGCAGCTGTTGGACTTGGACATCGTTTTGATGAAATCAAACAAATGTATC
GTAAAGTAAACATGATGTTTGGCGATATCATTAAAGTAACTCCTTCATCAAAAGTAGTTGGTGATATGGCACTCTTTATG
ATTCAAAACGAATTGACAGAAGAGGATGTCTATGCGCGAGGAAATGAGCTTAACTTCCCTGAATCAGTAGTCTCATTCTT
CCGTGGTGATTTAGGACAGCCTGTTGGAGGTTTCCCAGAAGAACTACAAAAAATTATTGTAAAAGACAAATCGGTCATTA
TGGATCGTCCAGGATTACATGCCGAAAAAGTTGATTTTGCAACTGTAAAAGCTGACTTGGAACAAAAAATTGGTTATGAA
CCAGGTGATCATGAAGTTATCTCTTACATTATGTATCCACAAGTTTTCCTTGATTATCAAAAAATGCAAAGAGAATTTGG
AGCTGTCACACTACTCGATACTCCAACTTTCTTACACGGAATGCGCCTCAATGAAAAAATTGAAGTCCAAATTGAAAAAG
GTAAAACGCTCAGCATTCGTTTAGATGAAATAGGAGAACCTGACCTCGCTGGAAATCGTGTGCTCTTCTTTAACTTGAAC
GGTCAGCGTCGTGAAGTTGTTATTAATGACCAATCCGTTCAAACTCAAATTGTAGCTAAACGTAAGGCCGAAACAGGTAA
TCCAAACCAAATTGGAGCAACTATGCCCGGTTCTGTTCTTGAAATCCTAGTTAAAGCTGGAGATAAAGTTAAAAAAGGAC
AAGCTTTGATGGTTACTGAAGCCATGAAGATGGAAACGACCATTGAGTCACCATTTGATGGAGAGGTTATTGCCCTTCAT
GTTGTCAAAGGTGAAGCCATTCAAACACAAGACTTATTGATTGAAATTGACTAA

Upstream 100 bases:

>100_bases
TGTCAGTCGTTTAAAAGTGTATAAAAGATTTTTATAATATATGGAAGAGTGAAAGGAATTAATAATTACCTTTCCAAACA
AGCCTCATTAAGGAGTCAAA

Downstream 100 bases:

>100_bases
CTTTAAATTAACCCTACCATTATGGTAGGATTTTTTATTTTCTAAAAAAAAGTAATTTTAATTTTCAGAAAATATATAAT
TTTCGGAATAAAAAGTGTAT

Product: pyruvate carboxylase

Products: NA

Alternate protein names: Pyruvic carboxylase; PYC [H]

Number of amino acids: Translated: 1137; Mature: 1137

Protein sequence:

>1137_residues
MKKLLVANRGEIAVRVFRACNELGLSTVAVYAREDEYSVHRFKADESYLIGQGKKPIDAYLDIDDIIRVALESGADAIHP
GYGLLSENLEFATKVRAAGLVFVGPELHHLDIFGDKIKAKAAADEAQVPGIPGTNGAVDIDGALEFAQTYGYPVMIKAAL
GGGGRGMRVARNDAEMHDGYARAKSEAIGAFGSGEIYVEKYIENPKHIEVQILGDSHGNIVHLHERDCSVQRRNQKVIEI
APAVGLSPEFRNEICEAAVKLCKNVGYVNAGTVEFLVKDDKFYFIEVNPRVQVEHTITELITGVDIVQAQILIAQGKDLH
TEIGIPAQAEIPLLGSAIQCRITTEDPQNGFLPDTGKIDTYRSPGGFGIRLDVGNAYAGYEVTPYFDSLLVKVCTFANEF
SDSVRKMDRVLHEFRIRGVKTNIPFLINVIANENFTSGQATTTFIDNTPSLFNFPRLRDRGTKTLHYLSMITVNGFPGIE
NTEKRHFEEPRQPLLNIEKKKTAKNILDEQGADAVVEYVKNTKEVLLTDTTLRDAHQSLLATRLRLQDMKGIAQAIDQGL
PELFSAEMWGGATFDVAYRFLNESPWYRLRKLRKLMPNTMFQMLFRGSNAVGYQNYPDNVIEEFIHVAAHEGIDVFRIFD
SLNWLPQMEKSIQAVRDNGKIAEATICYTGDILDPSRPKYNIQYYKDLAKELEATGAHILAVKDMAGLLKPQAAYRLISE
LKDTVDLPIHLHTHDTSGNGIITYSGATQAGVDIIDVATASLAGGTSQPSMQSIYYALEHGPRHASINVKNAEQIDHYWE
DVRKYYAPFEAGITSPQTEVYMHEMPGGQYTNLKSQAAAVGLGHRFDEIKQMYRKVNMMFGDIIKVTPSSKVVGDMALFM
IQNELTEEDVYARGNELNFPESVVSFFRGDLGQPVGGFPEELQKIIVKDKSVIMDRPGLHAEKVDFATVKADLEQKIGYE
PGDHEVISYIMYPQVFLDYQKMQREFGAVTLLDTPTFLHGMRLNEKIEVQIEKGKTLSIRLDEIGEPDLAGNRVLFFNLN
GQRREVVINDQSVQTQIVAKRKAETGNPNQIGATMPGSVLEILVKAGDKVKKGQALMVTEAMKMETTIESPFDGEVIALH
VVKGEAIQTQDLLIEID

Sequences:

>Translated_1137_residues
MKKLLVANRGEIAVRVFRACNELGLSTVAVYAREDEYSVHRFKADESYLIGQGKKPIDAYLDIDDIIRVALESGADAIHP
GYGLLSENLEFATKVRAAGLVFVGPELHHLDIFGDKIKAKAAADEAQVPGIPGTNGAVDIDGALEFAQTYGYPVMIKAAL
GGGGRGMRVARNDAEMHDGYARAKSEAIGAFGSGEIYVEKYIENPKHIEVQILGDSHGNIVHLHERDCSVQRRNQKVIEI
APAVGLSPEFRNEICEAAVKLCKNVGYVNAGTVEFLVKDDKFYFIEVNPRVQVEHTITELITGVDIVQAQILIAQGKDLH
TEIGIPAQAEIPLLGSAIQCRITTEDPQNGFLPDTGKIDTYRSPGGFGIRLDVGNAYAGYEVTPYFDSLLVKVCTFANEF
SDSVRKMDRVLHEFRIRGVKTNIPFLINVIANENFTSGQATTTFIDNTPSLFNFPRLRDRGTKTLHYLSMITVNGFPGIE
NTEKRHFEEPRQPLLNIEKKKTAKNILDEQGADAVVEYVKNTKEVLLTDTTLRDAHQSLLATRLRLQDMKGIAQAIDQGL
PELFSAEMWGGATFDVAYRFLNESPWYRLRKLRKLMPNTMFQMLFRGSNAVGYQNYPDNVIEEFIHVAAHEGIDVFRIFD
SLNWLPQMEKSIQAVRDNGKIAEATICYTGDILDPSRPKYNIQYYKDLAKELEATGAHILAVKDMAGLLKPQAAYRLISE
LKDTVDLPIHLHTHDTSGNGIITYSGATQAGVDIIDVATASLAGGTSQPSMQSIYYALEHGPRHASINVKNAEQIDHYWE
DVRKYYAPFEAGITSPQTEVYMHEMPGGQYTNLKSQAAAVGLGHRFDEIKQMYRKVNMMFGDIIKVTPSSKVVGDMALFM
IQNELTEEDVYARGNELNFPESVVSFFRGDLGQPVGGFPEELQKIIVKDKSVIMDRPGLHAEKVDFATVKADLEQKIGYE
PGDHEVISYIMYPQVFLDYQKMQREFGAVTLLDTPTFLHGMRLNEKIEVQIEKGKTLSIRLDEIGEPDLAGNRVLFFNLN
GQRREVVINDQSVQTQIVAKRKAETGNPNQIGATMPGSVLEILVKAGDKVKKGQALMVTEAMKMETTIESPFDGEVIALH
VVKGEAIQTQDLLIEID
>Mature_1137_residues
MKKLLVANRGEIAVRVFRACNELGLSTVAVYAREDEYSVHRFKADESYLIGQGKKPIDAYLDIDDIIRVALESGADAIHP
GYGLLSENLEFATKVRAAGLVFVGPELHHLDIFGDKIKAKAAADEAQVPGIPGTNGAVDIDGALEFAQTYGYPVMIKAAL
GGGGRGMRVARNDAEMHDGYARAKSEAIGAFGSGEIYVEKYIENPKHIEVQILGDSHGNIVHLHERDCSVQRRNQKVIEI
APAVGLSPEFRNEICEAAVKLCKNVGYVNAGTVEFLVKDDKFYFIEVNPRVQVEHTITELITGVDIVQAQILIAQGKDLH
TEIGIPAQAEIPLLGSAIQCRITTEDPQNGFLPDTGKIDTYRSPGGFGIRLDVGNAYAGYEVTPYFDSLLVKVCTFANEF
SDSVRKMDRVLHEFRIRGVKTNIPFLINVIANENFTSGQATTTFIDNTPSLFNFPRLRDRGTKTLHYLSMITVNGFPGIE
NTEKRHFEEPRQPLLNIEKKKTAKNILDEQGADAVVEYVKNTKEVLLTDTTLRDAHQSLLATRLRLQDMKGIAQAIDQGL
PELFSAEMWGGATFDVAYRFLNESPWYRLRKLRKLMPNTMFQMLFRGSNAVGYQNYPDNVIEEFIHVAAHEGIDVFRIFD
SLNWLPQMEKSIQAVRDNGKIAEATICYTGDILDPSRPKYNIQYYKDLAKELEATGAHILAVKDMAGLLKPQAAYRLISE
LKDTVDLPIHLHTHDTSGNGIITYSGATQAGVDIIDVATASLAGGTSQPSMQSIYYALEHGPRHASINVKNAEQIDHYWE
DVRKYYAPFEAGITSPQTEVYMHEMPGGQYTNLKSQAAAVGLGHRFDEIKQMYRKVNMMFGDIIKVTPSSKVVGDMALFM
IQNELTEEDVYARGNELNFPESVVSFFRGDLGQPVGGFPEELQKIIVKDKSVIMDRPGLHAEKVDFATVKADLEQKIGYE
PGDHEVISYIMYPQVFLDYQKMQREFGAVTLLDTPTFLHGMRLNEKIEVQIEKGKTLSIRLDEIGEPDLAGNRVLFFNLN
GQRREVVINDQSVQTQIVAKRKAETGNPNQIGATMPGSVLEILVKAGDKVKKGQALMVTEAMKMETTIESPFDGEVIALH
VVKGEAIQTQDLLIEID

Specific function: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic functi

COG id: COG1038

COG function: function code C; Pyruvate carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=1144, Percent_Identity=49.4755244755245, Blast_Score=1088, Evalue=0.0,
Organism=Homo sapiens, GI106049295, Length=1144, Percent_Identity=49.4755244755245, Blast_Score=1088, Evalue=0.0,
Organism=Homo sapiens, GI106049292, Length=1144, Percent_Identity=49.4755244755245, Blast_Score=1088, Evalue=0.0,
Organism=Homo sapiens, GI189095269, Length=449, Percent_Identity=44.7661469933185, Blast_Score=377, Evalue=1e-104,
Organism=Homo sapiens, GI65506442, Length=449, Percent_Identity=44.7661469933185, Blast_Score=377, Evalue=1e-104,
Organism=Homo sapiens, GI295821183, Length=449, Percent_Identity=44.7661469933185, Blast_Score=377, Evalue=1e-104,
Organism=Homo sapiens, GI116805327, Length=450, Percent_Identity=43.5555555555556, Blast_Score=355, Evalue=1e-97,
Organism=Homo sapiens, GI38679960, Length=504, Percent_Identity=30.952380952381, Blast_Score=232, Evalue=1e-60,
Organism=Homo sapiens, GI38679971, Length=504, Percent_Identity=30.952380952381, Blast_Score=232, Evalue=1e-60,
Organism=Homo sapiens, GI38679977, Length=504, Percent_Identity=30.952380952381, Blast_Score=232, Evalue=1e-60,
Organism=Homo sapiens, GI38679967, Length=504, Percent_Identity=30.952380952381, Blast_Score=232, Evalue=1e-60,
Organism=Homo sapiens, GI38679974, Length=504, Percent_Identity=30.952380952381, Blast_Score=232, Evalue=2e-60,
Organism=Homo sapiens, GI134142062, Length=506, Percent_Identity=31.2252964426877, Blast_Score=225, Evalue=2e-58,
Organism=Escherichia coli, GI1789654, Length=453, Percent_Identity=45.6953642384106, Blast_Score=392, Evalue=1e-110,
Organism=Escherichia coli, GI1786216, Length=313, Percent_Identity=22.3642172523962, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17562816, Length=1143, Percent_Identity=49.7812773403325, Blast_Score=1102, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17567343, Length=447, Percent_Identity=44.5190156599553, Blast_Score=364, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI71987519, Length=541, Percent_Identity=40.1109057301294, Blast_Score=353, Evalue=2e-97,
Organism=Caenorhabditis elegans, GI133931226, Length=493, Percent_Identity=30.0202839756592, Blast_Score=214, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI71997168, Length=438, Percent_Identity=29.2237442922374, Blast_Score=199, Evalue=5e-51,
Organism=Caenorhabditis elegans, GI71997163, Length=438, Percent_Identity=29.2237442922374, Blast_Score=199, Evalue=6e-51,
Organism=Saccharomyces cerevisiae, GI6319695, Length=1154, Percent_Identity=48.1802426343154, Blast_Score=1073, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6321376, Length=1151, Percent_Identity=48.6533449174631, Blast_Score=1060, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319685, Length=446, Percent_Identity=36.322869955157, Blast_Score=286, Evalue=1e-77,
Organism=Saccharomyces cerevisiae, GI6323863, Length=438, Percent_Identity=34.9315068493151, Blast_Score=241, Evalue=5e-64,
Organism=Saccharomyces cerevisiae, GI6324343, Length=514, Percent_Identity=32.1011673151751, Blast_Score=233, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24652212, Length=1147, Percent_Identity=49.694856146469, Blast_Score=1101, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652210, Length=1147, Percent_Identity=49.694856146469, Blast_Score=1101, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652214, Length=1147, Percent_Identity=49.694856146469, Blast_Score=1101, Evalue=0.0,
Organism=Drosophila melanogaster, GI19921944, Length=1147, Percent_Identity=49.694856146469, Blast_Score=1101, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652216, Length=1147, Percent_Identity=49.694856146469, Blast_Score=1101, Evalue=0.0,
Organism=Drosophila melanogaster, GI281363050, Length=1163, Percent_Identity=48.9251934651763, Blast_Score=1096, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652224, Length=1163, Percent_Identity=48.9251934651763, Blast_Score=1096, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652222, Length=1163, Percent_Identity=48.9251934651763, Blast_Score=1096, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652220, Length=1163, Percent_Identity=48.9251934651763, Blast_Score=1096, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652218, Length=1163, Percent_Identity=48.9251934651763, Blast_Score=1096, Evalue=0.0,
Organism=Drosophila melanogaster, GI24651757, Length=450, Percent_Identity=42.2222222222222, Blast_Score=343, Evalue=3e-94,
Organism=Drosophila melanogaster, GI24651759, Length=412, Percent_Identity=41.2621359223301, Blast_Score=303, Evalue=4e-82,
Organism=Drosophila melanogaster, GI161076407, Length=500, Percent_Identity=30, Blast_Score=215, Evalue=1e-55,
Organism=Drosophila melanogaster, GI24586460, Length=500, Percent_Identity=30, Blast_Score=215, Evalue=1e-55,
Organism=Drosophila melanogaster, GI24586458, Length=500, Percent_Identity=30, Blast_Score=215, Evalue=2e-55,
Organism=Drosophila melanogaster, GI161076409, Length=500, Percent_Identity=30, Blast_Score=214, Evalue=2e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR003379
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR000891
- InterPro:   IPR005930
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.1 [H]

Molecular weight: Translated: 126393; Mature: 126393

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS50975 ATP_GRASP ; PS00866 CPSASE_1 ; PS00867 CPSASE_2 ; PS50979 BC ; PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLLVANRGEIAVRVFRACNELGLSTVAVYAREDEYSVHRFKADESYLIGQGKKPIDAY
CCCEEEECCCHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEECCCCEEECCCCCCHHHH
LDIDDIIRVALESGADAIHPGYGLLSENLEFATKVRAAGLVFVGPELHHLDIFGDKIKAK
CCHHHHHHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHCCEEEECCCEEEEEEECCHHHHH
AAADEAQVPGIPGTNGAVDIDGALEFAQTYGYPVMIKAALGGGGRGMRVARNDAEMHDGY
HCCCCCCCCCCCCCCCCEEEHHHHHHHHHCCCCEEEEEEECCCCCCCEEECCCCHHHHHH
ARAKSEAIGAFGSGEIYVEKYIENPKHIEVQILGDSHGNIVHLHERDCSVQRRNQKVIEI
HHHHHHHCCCCCCCCEEEEEECCCCCEEEEEEEECCCCCEEEEECCCCCHHHCCCEEEEE
APAVGLSPEFRNEICEAAVKLCKNVGYVNAGTVEFLVKDDKFYFIEVNPRVQVEHTITEL
ECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCEEEEEEECCCEEEHHHHHHH
ITGVDIVQAQILIAQGKDLHTEIGIPAQAEIPLLGSAIQCRITTEDPQNGFLPDTGKIDT
HHCHHHHHEEEEEECCCCCEEECCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCC
YRSPGGFGIRLDVGNAYAGYEVTPYFDSLLVKVCTFANEFSDSVRKMDRVLHEFRIRGVK
CCCCCCEEEEEECCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
TNIPFLINVIANENFTSGQATTTFIDNTPSLFNFPRLRDRGTKTLHYLSMITVNGFPGIE
CCCCEEEEEEECCCCCCCCEEEEEECCCCCCCCCCCHHCCCCCCEEEEEEEEECCCCCCC
NTEKRHFEEPRQPLLNIEKKKTAKNILDEQGADAVVEYVKNTKEVLLTDTTLRDAHQSLL
CCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEECCHHHHHHHHHH
ATRLRLQDMKGIAQAIDQGLPELFSAEMWGGATFDVAYRFLNESPWYRLRKLRKLMPNTM
HHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHH
FQMLFRGSNAVGYQNYPDNVIEEFIHVAAHEGIDVFRIFDSLNWLPQMEKSIQAVRDNGK
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHCCCC
IAEATICYTGDILDPSRPKYNIQYYKDLAKELEATGAHILAVKDMAGLLKPQAAYRLISE
EEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEHHHHHHHCHHHHHHHHHH
LKDTVDLPIHLHTHDTSGNGIITYSGATQAGVDIIDVATASLAGGTSQPSMQSIYYALEH
HHHHCCCEEEEEEECCCCCEEEEECCCCCCCCEEEEHHHHHHCCCCCCCHHHHHHHHHHC
GPRHASINVKNAEQIDHYWEDVRKYYAPFEAGITSPQTEVYMHEMPGGQYTNLKSQAAAV
CCCEEEEECCCHHHHHHHHHHHHHHHCCHHCCCCCCCCEEEEEECCCCCCCCCHHHHHHH
GLGHRFDEIKQMYRKVNMMFGDIIKVTPSSKVVGDMALFMIQNELTEEDVYARGNELNFP
HCCCHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHCCHHHHHHCCCCCCCH
ESVVSFFRGDLGQPVGGFPEELQKIIVKDKSVIMDRPGLHAEKVDFATVKADLEQKIGYE
HHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHEECCCCCCCCCCHHHHHHHHHHHHCCCC
PGDHEVISYIMYPQVFLDYQKMQREFGAVTLLDTPTFLHGMRLNEKIEVQIEKGKTLSIR
CCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHCCCCCCEEEEEEECCCEEEEE
LDEIGEPDLAGNRVLFFNLNGQRREVVINDQSVQTQIVAKRKAETGNPNQIGATMPGSVL
ECCCCCCCCCCCEEEEEEECCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHH
EILVKAGDKVKKGQALMVTEAMKMETTIESPFDGEVIALHVVKGEAIQTQDLLIEID
HHHHHCCCCCCCCCEEEEEHHHHHHHHCCCCCCCCEEEEEEEECCCEEEECEEEEEC
>Mature Secondary Structure
MKKLLVANRGEIAVRVFRACNELGLSTVAVYAREDEYSVHRFKADESYLIGQGKKPIDAY
CCCEEEECCCHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEECCCCEEECCCCCCHHHH
LDIDDIIRVALESGADAIHPGYGLLSENLEFATKVRAAGLVFVGPELHHLDIFGDKIKAK
CCHHHHHHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHCCEEEECCCEEEEEEECCHHHHH
AAADEAQVPGIPGTNGAVDIDGALEFAQTYGYPVMIKAALGGGGRGMRVARNDAEMHDGY
HCCCCCCCCCCCCCCCCEEEHHHHHHHHHCCCCEEEEEEECCCCCCCEEECCCCHHHHHH
ARAKSEAIGAFGSGEIYVEKYIENPKHIEVQILGDSHGNIVHLHERDCSVQRRNQKVIEI
HHHHHHHCCCCCCCCEEEEEECCCCCEEEEEEEECCCCCEEEEECCCCCHHHCCCEEEEE
APAVGLSPEFRNEICEAAVKLCKNVGYVNAGTVEFLVKDDKFYFIEVNPRVQVEHTITEL
ECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCEEEEEEECCCEEEHHHHHHH
ITGVDIVQAQILIAQGKDLHTEIGIPAQAEIPLLGSAIQCRITTEDPQNGFLPDTGKIDT
HHCHHHHHEEEEEECCCCCEEECCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCC
YRSPGGFGIRLDVGNAYAGYEVTPYFDSLLVKVCTFANEFSDSVRKMDRVLHEFRIRGVK
CCCCCCEEEEEECCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
TNIPFLINVIANENFTSGQATTTFIDNTPSLFNFPRLRDRGTKTLHYLSMITVNGFPGIE
CCCCEEEEEEECCCCCCCCEEEEEECCCCCCCCCCCHHCCCCCCEEEEEEEEECCCCCCC
NTEKRHFEEPRQPLLNIEKKKTAKNILDEQGADAVVEYVKNTKEVLLTDTTLRDAHQSLL
CCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEECCHHHHHHHHHH
ATRLRLQDMKGIAQAIDQGLPELFSAEMWGGATFDVAYRFLNESPWYRLRKLRKLMPNTM
HHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHH
FQMLFRGSNAVGYQNYPDNVIEEFIHVAAHEGIDVFRIFDSLNWLPQMEKSIQAVRDNGK
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHCCCC
IAEATICYTGDILDPSRPKYNIQYYKDLAKELEATGAHILAVKDMAGLLKPQAAYRLISE
EEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEHHHHHHHCHHHHHHHHHH
LKDTVDLPIHLHTHDTSGNGIITYSGATQAGVDIIDVATASLAGGTSQPSMQSIYYALEH
HHHHCCCEEEEEEECCCCCEEEEECCCCCCCCEEEEHHHHHHCCCCCCCHHHHHHHHHHC
GPRHASINVKNAEQIDHYWEDVRKYYAPFEAGITSPQTEVYMHEMPGGQYTNLKSQAAAV
CCCEEEEECCCHHHHHHHHHHHHHHHCCHHCCCCCCCCEEEEEECCCCCCCCCHHHHHHH
GLGHRFDEIKQMYRKVNMMFGDIIKVTPSSKVVGDMALFMIQNELTEEDVYARGNELNFP
HCCCHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHCCHHHHHHCCCCCCCH
ESVVSFFRGDLGQPVGGFPEELQKIIVKDKSVIMDRPGLHAEKVDFATVKADLEQKIGYE
HHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHEECCCCCCCCCCHHHHHHHHHHHHCCCC
PGDHEVISYIMYPQVFLDYQKMQREFGAVTLLDTPTFLHGMRLNEKIEVQIEKGKTLSIR
CCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHCCCCCCEEEEEEECCCEEEEE
LDEIGEPDLAGNRVLFFNLNGQRREVVINDQSVQTQIVAKRKAETGNPNQIGATMPGSVL
ECCCCCCCCCCCEEEEEEECCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHH
EILVKAGDKVKKGQALMVTEAMKMETTIESPFDGEVIALHVVKGEAIQTQDLLIEID
HHHHHCCCCCCCCCEEEEEHHHHHHHHCCCCCCCCEEEEEEEECCCEEEECEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]