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The map label for this gene is clpC [H]

Identifier: 125623476

GI number: 125623476

Start: 602854

End: 605304

Strand: Direct

Name: clpC [H]

Synonym: llmg_0615

Alternate gene names: 125623476

Gene position: 602854-605304 (Clockwise)

Preceding gene: 125623475

Following gene: 125623477

Centisome position: 23.83

GC content: 38.6

Gene sequence:

>2451_bases
ATGAAATTTGAAAATGTAAAATATACACCAACACTGGACCGAATTTTCGAGAAAGCAGCAGAATATGCCCACCAATATCA
ATACGGTACGATTGAAAGTGCTCATTTATTGGCAGCAATGGCTACTACTTCAGGCTCAATTGCTTACAGTATTCTTGCTG
GAATGAATGTTGATTCTTCAGACTTACTGATTGATTTGGAAGATTTATCTAGCCATGTCAAAGTGAAACGTTCTGAATTA
CGTTTCTCTCCTCGCGCAGAAGAAGTGGTTACTGTAGCTAGCTTTTTGGCAGTTCATAATAATGCAGAAGCAGTAGGAAC
AGAGCATTTGCTTTATGCATTACTTCAAGTCGAAGATGGTTTTGGTCTTCAACTTTTGAAGTTACAAAAAATCAACATTG
TTTCTTTGCGAAAAGAAATTGAAAAAAGAACAGGACTTAAAGTTCCAGAAAACAAAAAAGCTGTAACACCAATGTCCAAA
CGTAAGATGGCAAAAGGGGTAGCAGAGAATTCAAGTACACCAACTTTGGATTCAGTTTCTTCAGATTTAACTGAAGCTGC
TCGTTCAGGAAAGCTTGACCCAATGATTGGTCGGGAAGCAGAAGTTGACCGTTTGATTCATATTCTTAGTCGTAGAACAA
AAAATAACCCTGTTTTAGTTGGTGAACCTGGTGTTGGTAAATCAGCAATAATCGAGGGATTGGCTCAAAGAATTGTCAAC
GGCCAAGTACCTATCGGTTTGATGAATAGCCGGATTATGGCTCTAAATATGGCAACTGTTGTTGCTGGTACAAAATTTAG
AGGTGAATTTGAAGACCGCTTGACAGCAATTGTTGAAGAAGTAAGTGCTGACCCAGATGTCATCATTTTCATTGATGAAT
TGCATACAATTATTGGTGCTGGCGGGGGCATGGACTCGGTCAATGATGCAGCAAATATTTTAAAACCAGCCCTTGCACGT
GGTGACTTTCAAATGGTTGGGGCAACGACTTATCATGAATACCAAAAATACATTGAAAAAGATGAAGCATTAGAACGTCG
TTTGGCAAGAATCAATGTTGATGAGCCAAGTCCAGATGAAGCCATTGCTATCTTACAAGGGTTACGTGAGAAATTTGAAG
ATTATCATCAAGTAAAATTTACTGACCAAGCGATTAAAAGCGCAGTGACACTTAGTGTTCGGTACATGACCAGTCGCAAA
TTGCCTGATAAAGCCATTGACTTGCTCGATGAAGCAGCGGCAGCAGTTAAAATTTCTGTTAAAAACCAAGAAACAAAACG
TCTTGAATTAGAGAAAGACTTAGTTAAAGCTCAAGAAGAACTAGCGGAAGCTGTCATTAAACTTGATGTTAAAGCCTCTC
GCATCAAAGAAAAAGCTGTTGAAAAAATTTCTGACAAGATTTATAAATTCTCAATAAAAGAGGAAAAACGTCAAGAAGTT
ACTGACCAAGCTGTTATTGCTGTTGCCTCAACGCTGACAGGTGTTCCAATTACTCAAATGACTAAATCTGAAAGCGACCG
TTTGATTAATCTTGAAAAAGAATTGCACAAACGGGTCGTTGGTCAAGAAGAAGCAATTTCTGCGGTTTCAAGAGCCATTC
GTCGGGCACGTTCTGGTGTGGCTGATAGTCGCCGTCCAATGGGTTCATTTATGTTTCTAGGACCAACTGGTGTTGGGAAA
ACTGAGTTAGCTAAGGCCTTGGCCGATAGTGTTTTTGGTAGCGAAGACAACATGATTCGAGTGGACATGAGTGAATTCAT
GGAAAAACATTCAACTTCACGCTTGATTGGGGCCCCTCCAGGATATGTTGGTTATGATGAAGGTGGTCAATTGACTGAAC
GCGTTCGTAATAAACCCTATTCTGTGGTTCTTTTAGATGAAGTTGAGAAAGCTCATCTTGACGTTTTCAATATCATGTTG
CAAATTCTAGATGATGGATTTGTGACAGATACAAAGGGCCGCAAAGTTGATTTTAGAAACACAATTATTATCATGACTTC
AAACTTGGGTGCAACGGCTCTTCGTGATGATAAAACAGTTGGTTTTGGTGCAAAAAATATCACGGCTGACTACTCAGCTA
TGCAATCAAGAATTTTGGAAGAACTTAAACGTCATTATCGTCCAGAGTTTCTCAATCGTATTGATGAAAACATTGTTTTC
CATTCATTGGAAAGTCAAGAAATTGAACAAATTGTTAAGATTATGAGCAAATCTTTGATTAAACGTTTGGCGGAACAAGA
TATTCATGTGAAACTTACGCCATCAGCAATAAAACTAATCGCTGAAGTAGGATTTGACCCAGAATATGGGGCACGTCCAT
TGCGTAAAGCACTCCAAAAAGAAGTTGAAGATCTTTTAAGTGAACAATTGCTCTCGGGTGAGATTAAAGCAGGAAATCAT
ATTTCCATTGGTGCTTCTAATAAAAAAATTAAAATCGCTCAAATTGTTTGA

Upstream 100 bases:

>100_bases
GAAGGGAATTTACTATTGCTCGTAATCACTGACGGAGCCATCAGTCCCTTTACTCGTGGTATAATGATGAAAAGTATAAT
AAACAGATTGGATCGTGACG

Downstream 100 bases:

>100_bases
GATGAAAGCCGTTTCATGTTATAATTAAATTAGAAATAAAGGAAAGGACAGTTCGAAAAGATTCAGAAGTCCTGAAAATT
CCAAAAGTTTAAGGACTTCA

Product: ATP-dependent Clp protease ATP-binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 816; Mature: 816

Protein sequence:

>816_residues
MKFENVKYTPTLDRIFEKAAEYAHQYQYGTIESAHLLAAMATTSGSIAYSILAGMNVDSSDLLIDLEDLSSHVKVKRSEL
RFSPRAEEVVTVASFLAVHNNAEAVGTEHLLYALLQVEDGFGLQLLKLQKINIVSLRKEIEKRTGLKVPENKKAVTPMSK
RKMAKGVAENSSTPTLDSVSSDLTEAARSGKLDPMIGREAEVDRLIHILSRRTKNNPVLVGEPGVGKSAIIEGLAQRIVN
GQVPIGLMNSRIMALNMATVVAGTKFRGEFEDRLTAIVEEVSADPDVIIFIDELHTIIGAGGGMDSVNDAANILKPALAR
GDFQMVGATTYHEYQKYIEKDEALERRLARINVDEPSPDEAIAILQGLREKFEDYHQVKFTDQAIKSAVTLSVRYMTSRK
LPDKAIDLLDEAAAAVKISVKNQETKRLELEKDLVKAQEELAEAVIKLDVKASRIKEKAVEKISDKIYKFSIKEEKRQEV
TDQAVIAVASTLTGVPITQMTKSESDRLINLEKELHKRVVGQEEAISAVSRAIRRARSGVADSRRPMGSFMFLGPTGVGK
TELAKALADSVFGSEDNMIRVDMSEFMEKHSTSRLIGAPPGYVGYDEGGQLTERVRNKPYSVVLLDEVEKAHLDVFNIML
QILDDGFVTDTKGRKVDFRNTIIIMTSNLGATALRDDKTVGFGAKNITADYSAMQSRILEELKRHYRPEFLNRIDENIVF
HSLESQEIEQIVKIMSKSLIKRLAEQDIHVKLTPSAIKLIAEVGFDPEYGARPLRKALQKEVEDLLSEQLLSGEIKAGNH
ISIGASNKKIKIAQIV

Sequences:

>Translated_816_residues
MKFENVKYTPTLDRIFEKAAEYAHQYQYGTIESAHLLAAMATTSGSIAYSILAGMNVDSSDLLIDLEDLSSHVKVKRSEL
RFSPRAEEVVTVASFLAVHNNAEAVGTEHLLYALLQVEDGFGLQLLKLQKINIVSLRKEIEKRTGLKVPENKKAVTPMSK
RKMAKGVAENSSTPTLDSVSSDLTEAARSGKLDPMIGREAEVDRLIHILSRRTKNNPVLVGEPGVGKSAIIEGLAQRIVN
GQVPIGLMNSRIMALNMATVVAGTKFRGEFEDRLTAIVEEVSADPDVIIFIDELHTIIGAGGGMDSVNDAANILKPALAR
GDFQMVGATTYHEYQKYIEKDEALERRLARINVDEPSPDEAIAILQGLREKFEDYHQVKFTDQAIKSAVTLSVRYMTSRK
LPDKAIDLLDEAAAAVKISVKNQETKRLELEKDLVKAQEELAEAVIKLDVKASRIKEKAVEKISDKIYKFSIKEEKRQEV
TDQAVIAVASTLTGVPITQMTKSESDRLINLEKELHKRVVGQEEAISAVSRAIRRARSGVADSRRPMGSFMFLGPTGVGK
TELAKALADSVFGSEDNMIRVDMSEFMEKHSTSRLIGAPPGYVGYDEGGQLTERVRNKPYSVVLLDEVEKAHLDVFNIML
QILDDGFVTDTKGRKVDFRNTIIIMTSNLGATALRDDKTVGFGAKNITADYSAMQSRILEELKRHYRPEFLNRIDENIVF
HSLESQEIEQIVKIMSKSLIKRLAEQDIHVKLTPSAIKLIAEVGFDPEYGARPLRKALQKEVEDLLSEQLLSGEIKAGNH
ISIGASNKKIKIAQIV
>Mature_816_residues
MKFENVKYTPTLDRIFEKAAEYAHQYQYGTIESAHLLAAMATTSGSIAYSILAGMNVDSSDLLIDLEDLSSHVKVKRSEL
RFSPRAEEVVTVASFLAVHNNAEAVGTEHLLYALLQVEDGFGLQLLKLQKINIVSLRKEIEKRTGLKVPENKKAVTPMSK
RKMAKGVAENSSTPTLDSVSSDLTEAARSGKLDPMIGREAEVDRLIHILSRRTKNNPVLVGEPGVGKSAIIEGLAQRIVN
GQVPIGLMNSRIMALNMATVVAGTKFRGEFEDRLTAIVEEVSADPDVIIFIDELHTIIGAGGGMDSVNDAANILKPALAR
GDFQMVGATTYHEYQKYIEKDEALERRLARINVDEPSPDEAIAILQGLREKFEDYHQVKFTDQAIKSAVTLSVRYMTSRK
LPDKAIDLLDEAAAAVKISVKNQETKRLELEKDLVKAQEELAEAVIKLDVKASRIKEKAVEKISDKIYKFSIKEEKRQEV
TDQAVIAVASTLTGVPITQMTKSESDRLINLEKELHKRVVGQEEAISAVSRAIRRARSGVADSRRPMGSFMFLGPTGVGK
TELAKALADSVFGSEDNMIRVDMSEFMEKHSTSRLIGAPPGYVGYDEGGQLTERVRNKPYSVVLLDEVEKAHLDVFNIML
QILDDGFVTDTKGRKVDFRNTIIIMTSNLGATALRDDKTVGFGAKNITADYSAMQSRILEELKRHYRPEFLNRIDENIVF
HSLESQEIEQIVKIMSKSLIKRLAEQDIHVKLTPSAIKLIAEVGFDPEYGARPLRKALQKEVEDLLSEQLLSGEIKAGNH
ISIGASNKKIKIAQIV

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=311, Percent_Identity=37.620578778135, Blast_Score=187, Evalue=4e-47,
Organism=Escherichia coli, GI1788943, Length=870, Percent_Identity=39.1954022988506, Blast_Score=563, Evalue=1e-161,
Organism=Escherichia coli, GI1787109, Length=809, Percent_Identity=35.4758961681088, Blast_Score=484, Evalue=1e-138,
Organism=Saccharomyces cerevisiae, GI6320464, Length=705, Percent_Identity=43.8297872340426, Blast_Score=546, Evalue=1e-156,
Organism=Saccharomyces cerevisiae, GI6323002, Length=894, Percent_Identity=35.6823266219239, Blast_Score=505, Evalue=1e-144,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 90364; Mature: 90364

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFENVKYTPTLDRIFEKAAEYAHQYQYGTIESAHLLAAMATTSGSIAYSILAGMNVDSS
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCC
DLLIDLEDLSSHVKVKRSELRFSPRAEEVVTVASFLAVHNNAEAVGTEHLLYALLQVEDG
CCEEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
FGLQLLKLQKINIVSLRKEIEKRTGLKVPENKKAVTPMSKRKMAKGVAENSSTPTLDSVS
CCEEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHH
SDLTEAARSGKLDPMIGREAEVDRLIHILSRRTKNNPVLVGEPGVGKSAIIEGLAQRIVN
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHC
GQVPIGLMNSRIMALNMATVVAGTKFRGEFEDRLTAIVEEVSADPDVIIFIDELHTIIGA
CCCCEEECCCEEEEEEHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCC
GGGMDSVNDAANILKPALARGDFQMVGATTYHEYQKYIEKDEALERRLARINVDEPSPDE
CCCCCCHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
AIAILQGLREKFEDYHQVKFTDQAIKSAVTLSVRYMTSRKLPDKAIDLLDEAAAAVKISV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHCCCCCHHHHHHHHHHHHEEEEEE
KNQETKRLELEKDLVKAQEELAEAVIKLDVKASRIKEKAVEKISDKIYKFSIKEEKRQEV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEEEECHHHHHHHH
TDQAVIAVASTLTGVPITQMTKSESDRLINLEKELHKRVVGQEEAISAVSRAIRRARSGV
HHHHHHHHHHHHCCCCHHHHHCCCCCCEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
ADSRRPMGSFMFLGPTGVGKTELAKALADSVFGSEDNMIRVDMSEFMEKHSTSRLIGAPP
CCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHCCCCEECCCC
GYVGYDEGGQLTERVRNKPYSVVLLDEVEKAHLDVFNIMLQILDDGFVTDTKGRKVDFRN
CCCCCCCCCHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCEECCCCCEEECCC
TIIIMTSNLGATALRDDKTVGFGAKNITADYSAMQSRILEELKRHYRPEFLNRIDENIVF
EEEEEECCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHE
HSLESQEIEQIVKIMSKSLIKRLAEQDIHVKLTPSAIKLIAEVGFDPEYGARPLRKALQK
ECCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHCCCCCCCCHHHHHHHHH
EVEDLLSEQLLSGEIKAGNHISIGASNKKIKIAQIV
HHHHHHHHHHHCCCCCCCCEEEECCCCCEEEEEECC
>Mature Secondary Structure
MKFENVKYTPTLDRIFEKAAEYAHQYQYGTIESAHLLAAMATTSGSIAYSILAGMNVDSS
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCC
DLLIDLEDLSSHVKVKRSELRFSPRAEEVVTVASFLAVHNNAEAVGTEHLLYALLQVEDG
CCEEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
FGLQLLKLQKINIVSLRKEIEKRTGLKVPENKKAVTPMSKRKMAKGVAENSSTPTLDSVS
CCEEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHH
SDLTEAARSGKLDPMIGREAEVDRLIHILSRRTKNNPVLVGEPGVGKSAIIEGLAQRIVN
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHC
GQVPIGLMNSRIMALNMATVVAGTKFRGEFEDRLTAIVEEVSADPDVIIFIDELHTIIGA
CCCCEEECCCEEEEEEHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCC
GGGMDSVNDAANILKPALARGDFQMVGATTYHEYQKYIEKDEALERRLARINVDEPSPDE
CCCCCCHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
AIAILQGLREKFEDYHQVKFTDQAIKSAVTLSVRYMTSRKLPDKAIDLLDEAAAAVKISV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHCCCCCHHHHHHHHHHHHEEEEEE
KNQETKRLELEKDLVKAQEELAEAVIKLDVKASRIKEKAVEKISDKIYKFSIKEEKRQEV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEEEECHHHHHHHH
TDQAVIAVASTLTGVPITQMTKSESDRLINLEKELHKRVVGQEEAISAVSRAIRRARSGV
HHHHHHHHHHHHCCCCHHHHHCCCCCCEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
ADSRRPMGSFMFLGPTGVGKTELAKALADSVFGSEDNMIRVDMSEFMEKHSTSRLIGAPP
CCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHCCCCEECCCC
GYVGYDEGGQLTERVRNKPYSVVLLDEVEKAHLDVFNIMLQILDDGFVTDTKGRKVDFRN
CCCCCCCCCHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCEECCCCCEEECCC
TIIIMTSNLGATALRDDKTVGFGAKNITADYSAMQSRILEELKRHYRPEFLNRIDENIVF
EEEEEECCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHE
HSLESQEIEQIVKIMSKSLIKRLAEQDIHVKLTPSAIKLIAEVGFDPEYGARPLRKALQK
ECCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHCCCCCCCCHHHHHHHHH
EVEDLLSEQLLSGEIKAGNHISIGASNKKIKIAQIV
HHHHHHHHHHHCCCCCCCCEEEECCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]