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The map label for this gene is celA [H]

Identifier: 125623308

GI number: 125623308

Start: 431698

End: 433134

Strand: Direct

Name: celA [H]

Synonym: llmg_0441

Alternate gene names: 125623308

Gene position: 431698-433134 (Clockwise)

Preceding gene: 125623307

Following gene: 125623309

Centisome position: 17.07

GC content: 36.67

Gene sequence:

>1437_bases
ATGACTTTAAAAAAAGACTTCCTCTGGGGAGGAGCAGTTGCTGCACATCAACTTGAAGGAGGCTGGAATGCTGGTGGAAA
GGGAGTTTCCGTAGCAGATGTGATGACAGCAGGTAGTAACGGCGTAGAAAGAAAAATCACAGATGGAGTAATTGAGGGAG
AAAATTACCCTAATCATGAAGCTATTGATTTCTATCACCACTATAAAGAAGATGTAGCACTTTTTGCAGAACTCGGTTTA
AATTGTTTTAGAACATCTATTGCTTGGACACGCATTTTTCCTAAGGGAGATGAGTCTGAACCTAACGAAGAGGGCTTGCA
ATTCTATGATGACTTATTTGATGAATGTTTAAAAAATGGTATTGAACCTGTCATTACTCTTTCTCACTTTGAACTTCCTT
ATCATTTAGTGACAGAGTATGGTGGATTCCGAAACCGAAAACTCATTGATTTCTTTGTCCATTTTTCAGAAGTAGTGATG
AATCGTTATAAAGATAAAGTTAAGTATTGGATGACTTTCAATGAAATTAATAACCAAGCAAACTTTATGCGCGACTTTGC
CCCTTTTACCAATTCTGGTTTGAAATTTCCAGAGGGAGCAAGCGAAAAAGAGCGTGAAGAAATCATGTATCAAGCGGCTC
ATTATGAACTTGTTGCCTCGGCCAAAGTTGTAGAGTTGGGACATAAAATTAATCCTGATTTCCAAATTGGTTGTATGATT
GCCATGTGTCCGATTTATCCTGCAACTTGTAAACCGGAAGACATGATGGCTTCAACCGTTGCTATGCAACGTCGTTATTG
GTTTGCAGATGTCCACGTTCGCGGACATTACCCAAGTTATTTAAAGGCTTATTTTGAACGTAAAGAATTTAAACTTGATA
TTAGTGATGAAGACTTAGAAGTTTTGAAAAATGGAAAAGTTGATTATATTGGTTTTTCTTACTATATGAGTTTTGCAATT
AAGGACCATGGAAAAGCCCCAACTTTTGATTATAACGAAGATAAAGATTTAGTTAAAAATGACTATGTTAAGGCTTCTGA
ATGGGGGTGGCAAATTGACCCATTAGGTTTACGTTATGCGATGAATTGGTTCTATGAACGTTATGAAAAACCACTTTTCA
TTGTTGAAAATGGCTTTGGTGCTGTAGATGAAGTTGAAGCTGATGGAAGTATTCACGACCCATATCGAATTGAATATTTA
AAAGCTCATATAGAATCAATGAAAGAAGCTGTTGAATATGATGGGGTTGATTTAATGGGATATACTCCTTGGGGCTTTAT
TGACCTTGTTTCTGCTGGAACCGGTGAGATGAAAAAACGCTATGGTGTCATCTATGTGGACAAAGATAATGAAGGAAATG
GAACATTAAAACGCTCTAAAAAAGATTCATTTGATTGGTATCAGAAAGTTATTGCAACCAATGGTGAAGAACTTTAA

Upstream 100 bases:

>100_bases
CTGCCGAATAATTGCAAAATTTAGATGAGCTCAAGACTTCTTGAGCTTATCTTGTTAAGAAATGATAATTTAATAATTCT
AATAATTACAAGGAGAAATT

Downstream 100 bases:

>100_bases
AATTGAAAGACACGAAAGTGTCTTTTTATTTTTACTATAATGTAAAAAAAACACTTCAAAATAGGAAAAGGTAGTATAAA
GGGTACATCTGTGTATTTTA

Product: 6-phospho-beta-glucosidase

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 478; Mature: 477

Protein sequence:

>478_residues
MTLKKDFLWGGAVAAHQLEGGWNAGGKGVSVADVMTAGSNGVERKITDGVIEGENYPNHEAIDFYHHYKEDVALFAELGL
NCFRTSIAWTRIFPKGDESEPNEEGLQFYDDLFDECLKNGIEPVITLSHFELPYHLVTEYGGFRNRKLIDFFVHFSEVVM
NRYKDKVKYWMTFNEINNQANFMRDFAPFTNSGLKFPEGASEKEREEIMYQAAHYELVASAKVVELGHKINPDFQIGCMI
AMCPIYPATCKPEDMMASTVAMQRRYWFADVHVRGHYPSYLKAYFERKEFKLDISDEDLEVLKNGKVDYIGFSYYMSFAI
KDHGKAPTFDYNEDKDLVKNDYVKASEWGWQIDPLGLRYAMNWFYERYEKPLFIVENGFGAVDEVEADGSIHDPYRIEYL
KAHIESMKEAVEYDGVDLMGYTPWGFIDLVSAGTGEMKKRYGVIYVDKDNEGNGTLKRSKKDSFDWYQKVIATNGEEL

Sequences:

>Translated_478_residues
MTLKKDFLWGGAVAAHQLEGGWNAGGKGVSVADVMTAGSNGVERKITDGVIEGENYPNHEAIDFYHHYKEDVALFAELGL
NCFRTSIAWTRIFPKGDESEPNEEGLQFYDDLFDECLKNGIEPVITLSHFELPYHLVTEYGGFRNRKLIDFFVHFSEVVM
NRYKDKVKYWMTFNEINNQANFMRDFAPFTNSGLKFPEGASEKEREEIMYQAAHYELVASAKVVELGHKINPDFQIGCMI
AMCPIYPATCKPEDMMASTVAMQRRYWFADVHVRGHYPSYLKAYFERKEFKLDISDEDLEVLKNGKVDYIGFSYYMSFAI
KDHGKAPTFDYNEDKDLVKNDYVKASEWGWQIDPLGLRYAMNWFYERYEKPLFIVENGFGAVDEVEADGSIHDPYRIEYL
KAHIESMKEAVEYDGVDLMGYTPWGFIDLVSAGTGEMKKRYGVIYVDKDNEGNGTLKRSKKDSFDWYQKVIATNGEEL
>Mature_477_residues
TLKKDFLWGGAVAAHQLEGGWNAGGKGVSVADVMTAGSNGVERKITDGVIEGENYPNHEAIDFYHHYKEDVALFAELGLN
CFRTSIAWTRIFPKGDESEPNEEGLQFYDDLFDECLKNGIEPVITLSHFELPYHLVTEYGGFRNRKLIDFFVHFSEVVMN
RYKDKVKYWMTFNEINNQANFMRDFAPFTNSGLKFPEGASEKEREEIMYQAAHYELVASAKVVELGHKINPDFQIGCMIA
MCPIYPATCKPEDMMASTVAMQRRYWFADVHVRGHYPSYLKAYFERKEFKLDISDEDLEVLKNGKVDYIGFSYYMSFAIK
DHGKAPTFDYNEDKDLVKNDYVKASEWGWQIDPLGLRYAMNWFYERYEKPLFIVENGFGAVDEVEADGSIHDPYRIEYLK
AHIESMKEAVEYDGVDLMGYTPWGFIDLVSAGTGEMKKRYGVIYVDKDNEGNGTLKRSKKDSFDWYQKVIATNGEEL

Specific function: Catalyzes the hydrolysis of aryl-phospho-beta-D- glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Plays a major role in the utilization of arbutin or salicin as the sole carbon source. Bgl

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI110681710, Length=499, Percent_Identity=29.2585170340681, Blast_Score=185, Evalue=9e-47,
Organism=Homo sapiens, GI32481206, Length=492, Percent_Identity=28.4552845528455, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI13273313, Length=495, Percent_Identity=26.2626262626263, Blast_Score=163, Evalue=4e-40,
Organism=Homo sapiens, GI24497614, Length=494, Percent_Identity=27.9352226720648, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI28376633, Length=490, Percent_Identity=28.1632653061224, Blast_Score=141, Evalue=1e-33,
Organism=Escherichia coli, GI2367174, Length=478, Percent_Identity=61.0878661087866, Blast_Score=615, Evalue=1e-177,
Organism=Escherichia coli, GI1789070, Length=480, Percent_Identity=49.375, Blast_Score=485, Evalue=1e-138,
Organism=Escherichia coli, GI2367270, Length=472, Percent_Identity=49.5762711864407, Blast_Score=469, Evalue=1e-133,
Organism=Caenorhabditis elegans, GI17552856, Length=472, Percent_Identity=29.8728813559322, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17539390, Length=487, Percent_Identity=28.3367556468172, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI21356577, Length=498, Percent_Identity=27.5100401606426, Blast_Score=157, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 55071; Mature: 54939

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLKKDFLWGGAVAAHQLEGGWNAGGKGVSVADVMTAGSNGVERKITDGVIEGENYPNHE
CCCCCCCCCCCCHHHHEECCCCCCCCCCCCHHHHHCCCCCCCCHHHHCCEECCCCCCCCC
AIDFYHHYKEDVALFAELGLNCFRTSIAWTRIFPKGDESEPNEEGLQFYDDLFDECLKNG
HHHHHHHHHHHHHHHHHHCHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCC
IEPVITLSHFELPYHLVTEYGGFRNRKLIDFFVHFSEVVMNRYKDKVKYWMTFNEINNQA
CCEEEEEEECCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHCCHH
NFMRDFAPFTNSGLKFPEGASEKEREEIMYQAAHYELVASAKVVELGHKINPDFQIGCMI
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEE
AMCPIYPATCKPEDMMASTVAMQRRYWFADVHVRGHYPSYLKAYFERKEFKLDISDEDLE
EECCCCCCCCCCHHHHHHHHHHHHHEEEEEEEEECCCHHHHHHHHHHHHEEECCCCCHHH
VLKNGKVDYIGFSYYMSFAIKDHGKAPTFDYNEDKDLVKNDYVKASEWGWQIDPLGLRYA
HHHCCCEEEEEHHHEEEEEEECCCCCCCCCCCCCHHHHHHCCEECCCCCCEECCHHHHHH
MNWFYERYEKPLFIVENGFGAVDEVEADGSIHDPYRIEYLKAHIESMKEAVEYDGVDLMG
HHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEE
YTPWGFIDLVSAGTGEMKKRYGVIYVDKDNEGNGTLKRSKKDSFDWYQKVIATNGEEL
CCCCCHHHHHCCCCCHHHHHCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TLKKDFLWGGAVAAHQLEGGWNAGGKGVSVADVMTAGSNGVERKITDGVIEGENYPNHE
CCCCCCCCCCCHHHHEECCCCCCCCCCCCHHHHHCCCCCCCCHHHHCCEECCCCCCCCC
AIDFYHHYKEDVALFAELGLNCFRTSIAWTRIFPKGDESEPNEEGLQFYDDLFDECLKNG
HHHHHHHHHHHHHHHHHHCHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCC
IEPVITLSHFELPYHLVTEYGGFRNRKLIDFFVHFSEVVMNRYKDKVKYWMTFNEINNQA
CCEEEEEEECCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHCCHH
NFMRDFAPFTNSGLKFPEGASEKEREEIMYQAAHYELVASAKVVELGHKINPDFQIGCMI
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEE
AMCPIYPATCKPEDMMASTVAMQRRYWFADVHVRGHYPSYLKAYFERKEFKLDISDEDLE
EECCCCCCCCCCHHHHHHHHHHHHHEEEEEEEEECCCHHHHHHHHHHHHEEECCCCCHHH
VLKNGKVDYIGFSYYMSFAIKDHGKAPTFDYNEDKDLVKNDYVKASEWGWQIDPLGLRYA
HHHCCCEEEEEHHHEEEEEEECCCCCCCCCCCCCHHHHHHCCEECCCCCCEECCHHHHHH
MNWFYERYEKPLFIVENGFGAVDEVEADGSIHDPYRIEYLKAHIESMKEAVEYDGVDLMG
HHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEE
YTPWGFIDLVSAGTGEMKKRYGVIYVDKDNEGNGTLKRSKKDSFDWYQKVIATNGEEL
CCCCCHHHHHCCCCCHHHHHCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8125345; 9384377 [H]