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The map label for this gene is ptcC [H]

Identifier: 125623307

GI number: 125623307

Start: 430271

End: 431608

Strand: Direct

Name: ptcC [H]

Synonym: llmg_0440

Alternate gene names: 125623307

Gene position: 430271-431608 (Clockwise)

Preceding gene: 125623306

Following gene: 125623308

Centisome position: 17.01

GC content: 40.73

Gene sequence:

>1338_bases
ATGAACAATTTTATTCAAAACAAAATCATGCCTCCAATGATGAAATTTTTGAATACCCGTGCAGTCACGGCAATCAAAAA
TGGTATGATTTATCCTATCCCATTTATCATTATTGGTTCAGTATTCTTGATTCTTGGTCAACTGCCATTCCAAGCAGGAC
AAGACTTCATGAACAAAATCAAATTGGGCCCACTCTTTTTACAAATTAATAATGCTTCATTTGGTATTATGGCTTTGCTT
GCCGTGTTCGGTATTGCTTACGCTTGGGTTCGAGATGCAGGTTATGAAGGAGTACCCGCTGGTTTAACAGGTGTCATTGT
TCACATCTTGTTGCAACCAGACACAATCCATCAAGTAACAAGTGTTACTGACCCAACTAAAACATCAACAGCATTTCAAG
TAGGTGGTGTCATTGACCGAGCTTGGTTAGGTGGGAAAGGGATGGTTCTCTCAATCATCGTTGGACTCTTAGTAGGTTGG
ATTTACACTGGCTTTATGCGTCGGAACATCACAATCAAAATGCCAGAACAAGTTCCAGAAAACGTTGCCGCATCATTTAC
TTCACTTGTACCTGCAGGAGCAATCATTACAATGGCTGGTGTGGTTCATGGAATCACAACGATTGGCTTCAACACAACTT
TCATTGAGTTAGTTTATAAATGGATTCAAACACCATTGCAACACGTGACTGACGGTCCGGTTGGGGTCTTCGTTATTGCC
TTTATGCCAGTATTTATCTGGTGGTTCGGTGTTCACGGAGCGACAATCATTGGTGGGATTATGGGACCATTGCTTCAAGC
AAACTCTGCTGACAATGCTGCTCTCTACAAAGCAGGACATCTTAGCCTGTCAAATGGCGCCCATATCGTTACTCAATCAT
TTATGGACCAATACTTGACAGTTACTGGTTCTGGTTTGACCATTGGTTTGGTTATCTTCCTCTTAGTGAGTGCAAAATCA
GTTCAAGGTAAAACTTTAGGACGAATGGAAATTGGACCTGCAGTATTCAATATCAACGAACCTATTCTGTTTGGACTTCC
TATCGTTTTGAATCCAATTCTTGCTATTCCATTTATCTTGGCTCCGTTGATTTCAGGAATTTTGACTTACTTAGTGATTT
ATCTAGGAATCATTCCACCATTTAATGGTGCCTATGTTCCTTGGACAACCCCTGCGGTCTTGTCAGGATATCTAGTAGGT
GGCTGGCAAGGTATGGTTTGGCAAATTATTATTCTTGCTTTGACCACAGTTCTCTATTGGCCATTTGCCAAAGCTTATGA
CAATATTCTTCTGAAAGAAGAAGCTGAAACAGAAGCTGGAATTAATGCTGCCGAATAA

Upstream 100 bases:

>100_bases
AACCGCTTTCTTTACTTTGCCTATTAATGCTATAATGAAAATGTAGAAAAGATGGACGTGAAACCAGTTCATCAAAAAAA
GTAAAGGAGACTGTTCAACC

Downstream 100 bases:

>100_bases
TTGCAAAATTTAGATGAGCTCAAGACTTCTTGAGCTTATCTTGTTAAGAAATGATAATTTAATAATTCTAATAATTACAA
GGAGAAATTATGACTTTAAA

Product: cellobiose-specific PTS system IIC component

Products: pyruvate; diacetylchitobiose-6-phosphate [Cytoplasm]; cellobiose-6-phosphate [Cytoplasm] [C]

Alternate protein names: Putative PTS system EIIC component [H]

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MNNFIQNKIMPPMMKFLNTRAVTAIKNGMIYPIPFIIIGSVFLILGQLPFQAGQDFMNKIKLGPLFLQINNASFGIMALL
AVFGIAYAWVRDAGYEGVPAGLTGVIVHILLQPDTIHQVTSVTDPTKTSTAFQVGGVIDRAWLGGKGMVLSIIVGLLVGW
IYTGFMRRNITIKMPEQVPENVAASFTSLVPAGAIITMAGVVHGITTIGFNTTFIELVYKWIQTPLQHVTDGPVGVFVIA
FMPVFIWWFGVHGATIIGGIMGPLLQANSADNAALYKAGHLSLSNGAHIVTQSFMDQYLTVTGSGLTIGLVIFLLVSAKS
VQGKTLGRMEIGPAVFNINEPILFGLPIVLNPILAIPFILAPLISGILTYLVIYLGIIPPFNGAYVPWTTPAVLSGYLVG
GWQGMVWQIIILALTTVLYWPFAKAYDNILLKEEAETEAGINAAE

Sequences:

>Translated_445_residues
MNNFIQNKIMPPMMKFLNTRAVTAIKNGMIYPIPFIIIGSVFLILGQLPFQAGQDFMNKIKLGPLFLQINNASFGIMALL
AVFGIAYAWVRDAGYEGVPAGLTGVIVHILLQPDTIHQVTSVTDPTKTSTAFQVGGVIDRAWLGGKGMVLSIIVGLLVGW
IYTGFMRRNITIKMPEQVPENVAASFTSLVPAGAIITMAGVVHGITTIGFNTTFIELVYKWIQTPLQHVTDGPVGVFVIA
FMPVFIWWFGVHGATIIGGIMGPLLQANSADNAALYKAGHLSLSNGAHIVTQSFMDQYLTVTGSGLTIGLVIFLLVSAKS
VQGKTLGRMEIGPAVFNINEPILFGLPIVLNPILAIPFILAPLISGILTYLVIYLGIIPPFNGAYVPWTTPAVLSGYLVG
GWQGMVWQIIILALTTVLYWPFAKAYDNILLKEEAETEAGINAAE
>Mature_445_residues
MNNFIQNKIMPPMMKFLNTRAVTAIKNGMIYPIPFIIIGSVFLILGQLPFQAGQDFMNKIKLGPLFLQINNASFGIMALL
AVFGIAYAWVRDAGYEGVPAGLTGVIVHILLQPDTIHQVTSVTDPTKTSTAFQVGGVIDRAWLGGKGMVLSIIVGLLVGW
IYTGFMRRNITIKMPEQVPENVAASFTSLVPAGAIITMAGVVHGITTIGFNTTFIELVYKWIQTPLQHVTDGPVGVFVIA
FMPVFIWWFGVHGATIIGGIMGPLLQANSADNAALYKAGHLSLSNGAHIVTQSFMDQYLTVTGSGLTIGLVIFLLVSAKS
VQGKTLGRMEIGPAVFNINEPILFGLPIVLNPILAIPFILAPLISGILTYLVIYLGIIPPFNGAYVPWTTPAVLSGYLVG
GWQGMVWQIIILALTTVLYWPFAKAYDNILLKEEAETEAGINAAE

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane [H]

COG id: COG1455

COG function: function code G; Phosphotransferase system cellobiose-specific component IIC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=459, Percent_Identity=29.1938997821351, Blast_Score=186, Evalue=3e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: NA

Molecular weight: Translated: 47990; Mature: 47990

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNFIQNKIMPPMMKFLNTRAVTAIKNGMIYPIPFIIIGSVFLILGQLPFQAGQDFMNKI
CCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
KLGPLFLQINNASFGIMALLAVFGIAYAWVRDAGYEGVPAGLTGVIVHILLQPDTIHQVT
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCHHHHHH
SVTDPTKTSTAFQVGGVIDRAWLGGKGMVLSIIVGLLVGWIYTGFMRRNITIKMPEQVPE
CCCCCCCCCCCEECCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHHH
NVAASFTSLVPAGAIITMAGVVHGITTIGFNTTFIELVYKWIQTPLQHVTDGPVGVFVIA
HHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
FMPVFIWWFGVHGATIIGGIMGPLLQANSADNAALYKAGHLSLSNGAHIVTQSFMDQYLT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCEECCCCCHHHHHHHHHHHHE
VTGSGLTIGLVIFLLVSAKSVQGKTLGRMEIGPAVFNINEPILFGLPIVLNPILAIPFIL
ECCCCHHHHHHHHHHHHCCCCCCCCCCCEEECCEEEECCCCHHCCCHHHHHHHHHHHHHH
APLISGILTYLVIYLGIIPPFNGAYVPWTTPAVLSGYLVGGWQGMVWQIIILALTTVLYW
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCHHHCCHHHHHHHHHHHHHHHHHHH
PFAKAYDNILLKEEAETEAGINAAE
HHHHHHHHHHCCCCCHHHCCCCCCC
>Mature Secondary Structure
MNNFIQNKIMPPMMKFLNTRAVTAIKNGMIYPIPFIIIGSVFLILGQLPFQAGQDFMNKI
CCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
KLGPLFLQINNASFGIMALLAVFGIAYAWVRDAGYEGVPAGLTGVIVHILLQPDTIHQVT
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCHHHHHH
SVTDPTKTSTAFQVGGVIDRAWLGGKGMVLSIIVGLLVGWIYTGFMRRNITIKMPEQVPE
CCCCCCCCCCCEECCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHHH
NVAASFTSLVPAGAIITMAGVVHGITTIGFNTTFIELVYKWIQTPLQHVTDGPVGVFVIA
HHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
FMPVFIWWFGVHGATIIGGIMGPLLQANSADNAALYKAGHLSLSNGAHIVTQSFMDQYLT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCEECCCCCHHHHHHHHHHHHE
VTGSGLTIGLVIFLLVSAKSVQGKTLGRMEIGPAVFNINEPILFGLPIVLNPILAIPFIL
ECCCCHHHHHHHHHHHHCCCCCCCCCCCEEECCEEEECCCCHHCCCHHHHHHHHHHHHHH
APLISGILTYLVIYLGIIPPFNGAYVPWTTPAVLSGYLVGGWQGMVWQIIILALTTVLYW
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCHHHCCHHHHHHHHHHHHHHHHHHH
PFAKAYDNILLKEEAETEAGINAAE
HHHHHHHHHHCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: diacetylchitobiose [Periplasm]; phosphoenolpyruvate; cellobiose [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + diacetylchitobiose [Periplasm] = pyruvate + diacetylchitobiose-6-phosphate [Cytoplasm] phosphoenolpyruvate + cellobiose [Periplasm] = cellobiose-6-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]