Click here to switch to the map view.

The map label for this gene is ydgF [H]

Identifier: 125623245

GI number: 125623245

Start: 369088

End: 370467

Strand: Reverse

Name: ydgF [H]

Synonym: llmg_0376

Alternate gene names: 125623245

Gene position: 370467-369088 (Counterclockwise)

Preceding gene: 125623249

Following gene: 125623244

Centisome position: 14.65

GC content: 37.68

Gene sequence:

>1380_bases
TTGGAAGACATTCAAAAGAATCATGAAGCCCAAAGGGGCTTACAAAACCGGCATATTCAACTCATTGCAATTGCCGGCAC
AATTGGTACTGGACTTTTTCTCGGTGCCGGAAAAACAATTCAAATGACTGGACCAAGTGTCATTTTCGCTTATATTTTAA
TTGGGATTGCTATGTTCTTTTTCCTTAGAACTATCGGGGAAATGCTCTATAATGACCCTAGTCAGCATTCATTTTTAAAT
TTTGTTACCAAATATTCAGGAATCAGAACAGGTTACTTCACTCAGTGGTCTTATTGGTTAGTTATTGTTTTTGTCTGTAT
CTCTGAATTGACGGCCATTGGAACTTATATTCAATTTTGGCTTCCTCATCTTCCTTTATGGTTGATTGAAATTGTGATGC
TCGCACTTCTTTTTGGTCTCAATACCTTAAATTCTCGTTTTTTTGGTGAAACTGAATTTTGGTTTGCTATGATTAAAGTG
GCAGCAATTCTTGGAATGATTGTAACTGCCATCATTCTCGTAGCAAGTAATTTCCATTACACCACAGTCTTAAGTGGTAA
AACGGTTAATGATACGGCTTCTCTAAATAATATTTTTGACGGTTTCCAACTTTTCCCACATGGTGCTTGGAATTTTGTCG
GAGCCCTACAAATGGTGATGTTTGCTTTCACTTCGATGGAATTTATCGGAATGACCGCCGCAGAAACAGTTAACCCTAAA
AAGAGTCTACCAAAAGCTATTAATCAAATCCCTGTCCGTATCTTGCTTTTCTACGTCGGAGCACTTCTGGCAATTATGGC
AATTTTTAATTGGCACTATATTCCAGCAGACAAATCACCATTCGTTATTGTTTTCCAACTCATTGGAATCAAATGGGCTG
CAGCTCTCATTAACTTCGTGGTATTAACTTCTGCTGCTTCGGCTCTCAATAGCTCTCTCTTCTCAGCAACACGCAATATG
TACTCTCTTGCCAAACAGCATGACAAGGGAAGATTGACCGCTTTTACAAAACTTTCTAAAGCAGGCATCCCGATTAATGC
CCTTTATATGGCAACGGCTCTTTCTCTTTTAGCACCTGTCCTAACTTTAATTCCTCAAATAAAAAATGCTTTTAACTTTG
CTGCCTCTTGTACGACCAATTTATTTTTGGTAGTTTATTTTATTACTTTGTATACCTACTGGCAATATCGTAAGTCTGAT
GATTATAATCCTAATGGCTTTTTAACCCCTAAACCCACTATTGCTGTACCATTTATTGCGATTATCTTTGCCATCGTTTT
TGCTTCCTTGTTCTTCAATGCCGATACTTTTTATCCTGCTTTAGGAGCGATTGTTTGGACTCTTATCTTTGGGCTTTACT
CCCATTTCAAAAAAATCTAA

Upstream 100 bases:

>100_bases
TTTAGCAAAATAGAATATGACTCTTGATACAATTTTATTAATTTGGTATAATAATTAACACATTATCGGAATCATCTGAT
AATTTAAGGAGGAAAAACTT

Downstream 100 bases:

>100_bases
TTCAGGTTCACTCCTTTATAAAATAGAGCAGTCTCTGAAAATCTTAATGAAAAAGCGTATAATATTATATTATGAATACA
AATCAAAATGATGAAAACAT

Product: amino acid permease

Products: D-glycine [Cytoplasm]; D-alanine [Cytoplasm]; Proton [Cytoplasm]; D-serine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MEDIQKNHEAQRGLQNRHIQLIAIAGTIGTGLFLGAGKTIQMTGPSVIFAYILIGIAMFFFLRTIGEMLYNDPSQHSFLN
FVTKYSGIRTGYFTQWSYWLVIVFVCISELTAIGTYIQFWLPHLPLWLIEIVMLALLFGLNTLNSRFFGETEFWFAMIKV
AAILGMIVTAIILVASNFHYTTVLSGKTVNDTASLNNIFDGFQLFPHGAWNFVGALQMVMFAFTSMEFIGMTAAETVNPK
KSLPKAINQIPVRILLFYVGALLAIMAIFNWHYIPADKSPFVIVFQLIGIKWAAALINFVVLTSAASALNSSLFSATRNM
YSLAKQHDKGRLTAFTKLSKAGIPINALYMATALSLLAPVLTLIPQIKNAFNFAASCTTNLFLVVYFITLYTYWQYRKSD
DYNPNGFLTPKPTIAVPFIAIIFAIVFASLFFNADTFYPALGAIVWTLIFGLYSHFKKI

Sequences:

>Translated_459_residues
MEDIQKNHEAQRGLQNRHIQLIAIAGTIGTGLFLGAGKTIQMTGPSVIFAYILIGIAMFFFLRTIGEMLYNDPSQHSFLN
FVTKYSGIRTGYFTQWSYWLVIVFVCISELTAIGTYIQFWLPHLPLWLIEIVMLALLFGLNTLNSRFFGETEFWFAMIKV
AAILGMIVTAIILVASNFHYTTVLSGKTVNDTASLNNIFDGFQLFPHGAWNFVGALQMVMFAFTSMEFIGMTAAETVNPK
KSLPKAINQIPVRILLFYVGALLAIMAIFNWHYIPADKSPFVIVFQLIGIKWAAALINFVVLTSAASALNSSLFSATRNM
YSLAKQHDKGRLTAFTKLSKAGIPINALYMATALSLLAPVLTLIPQIKNAFNFAASCTTNLFLVVYFITLYTYWQYRKSD
DYNPNGFLTPKPTIAVPFIAIIFAIVFASLFFNADTFYPALGAIVWTLIFGLYSHFKKI
>Mature_459_residues
MEDIQKNHEAQRGLQNRHIQLIAIAGTIGTGLFLGAGKTIQMTGPSVIFAYILIGIAMFFFLRTIGEMLYNDPSQHSFLN
FVTKYSGIRTGYFTQWSYWLVIVFVCISELTAIGTYIQFWLPHLPLWLIEIVMLALLFGLNTLNSRFFGETEFWFAMIKV
AAILGMIVTAIILVASNFHYTTVLSGKTVNDTASLNNIFDGFQLFPHGAWNFVGALQMVMFAFTSMEFIGMTAAETVNPK
KSLPKAINQIPVRILLFYVGALLAIMAIFNWHYIPADKSPFVIVFQLIGIKWAAALINFVVLTSAASALNSSLFSATRNM
YSLAKQHDKGRLTAFTKLSKAGIPINALYMATALSLLAPVLTLIPQIKNAFNFAASCTTNLFLVVYFITLYTYWQYRKSD
DYNPNGFLTPKPTIAVPFIAIIFAIVFASLFFNADTFYPALGAIVWTLIFGLYSHFKKI

Specific function: Probable amino-acid or metabolite transport protein [H]

COG id: COG1113

COG function: function code E; Gamma-aminobutyrate permease and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1790653, Length=403, Percent_Identity=42.1836228287841, Blast_Score=319, Evalue=3e-88,
Organism=Escherichia coli, GI1786789, Length=402, Percent_Identity=38.5572139303483, Blast_Score=288, Evalue=7e-79,
Organism=Escherichia coli, GI1786302, Length=463, Percent_Identity=34.341252699784, Blast_Score=288, Evalue=7e-79,
Organism=Escherichia coli, GI48994972, Length=469, Percent_Identity=36.8869936034115, Blast_Score=280, Evalue=1e-76,
Organism=Escherichia coli, GI1786602, Length=396, Percent_Identity=37.1212121212121, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI87081708, Length=369, Percent_Identity=34.1463414634146, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI87081915, Length=356, Percent_Identity=34.2696629213483, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI1788480, Length=370, Percent_Identity=34.0540540540541, Blast_Score=200, Evalue=1e-52,
Organism=Escherichia coli, GI1789017, Length=400, Percent_Identity=29.25, Blast_Score=190, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6324924, Length=432, Percent_Identity=28.7037037037037, Blast_Score=160, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6324061, Length=411, Percent_Identity=28.9537712895377, Blast_Score=158, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6320772, Length=383, Percent_Identity=29.5039164490862, Blast_Score=155, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6321053, Length=406, Percent_Identity=25.8620689655172, Blast_Score=146, Evalue=9e-36,
Organism=Saccharomyces cerevisiae, GI6322892, Length=356, Percent_Identity=29.7752808988764, Blast_Score=143, Evalue=7e-35,
Organism=Saccharomyces cerevisiae, GI6324990, Length=369, Percent_Identity=28.7262872628726, Blast_Score=142, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6319608, Length=385, Percent_Identity=26.7532467532467, Blast_Score=141, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6324059, Length=378, Percent_Identity=29.6296296296296, Blast_Score=137, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6324553, Length=356, Percent_Identity=28.6516853932584, Blast_Score=127, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6319824, Length=407, Percent_Identity=25.7985257985258, Blast_Score=122, Evalue=8e-29,
Organism=Saccharomyces cerevisiae, GI6321629, Length=374, Percent_Identity=26.7379679144385, Blast_Score=111, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6320251, Length=420, Percent_Identity=23.0952380952381, Blast_Score=110, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6320717, Length=374, Percent_Identity=24.331550802139, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6319542, Length=380, Percent_Identity=26.3157894736842, Blast_Score=104, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6319543, Length=389, Percent_Identity=24.6786632390745, Blast_Score=96, Evalue=9e-21,
Organism=Saccharomyces cerevisiae, GI6322967, Length=374, Percent_Identity=24.8663101604278, Blast_Score=91, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6320364, Length=502, Percent_Identity=22.7091633466135, Blast_Score=74, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6324981, Length=361, Percent_Identity=24.9307479224377, Blast_Score=71, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 51331; Mature: 51331

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDIQKNHEAQRGLQNRHIQLIAIAGTIGTGLFLGAGKTIQMTGPSVIFAYILIGIAMFF
CCCHHHHHHHHCCHHHCCEEEEEEECHHHHHHEECCCCEEEECCHHHHHHHHHHHHHHHH
FLRTIGEMLYNDPSQHSFLNFVTKYSGIRTGYFTQWSYWLVIVFVCISELTAIGTYIQFW
HHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPHLPLWLIEIVMLALLFGLNTLNSRFFGETEFWFAMIKVAAILGMIVTAIILVASNFHY
HHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
TTVLSGKTVNDTASLNNIFDGFQLFPHGAWNFVGALQMVMFAFTSMEFIGMTAAETVNPK
EEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCH
KSLPKAINQIPVRILLFYVGALLAIMAIFNWHYIPADKSPFVIVFQLIGIKWAAALINFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VLTSAASALNSSLFSATRNMYSLAKQHDKGRLTAFTKLSKAGIPINALYMATALSLLAPV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LTLIPQIKNAFNFAASCTTNLFLVVYFITLYTYWQYRKSDDYNPNGFLTPKPTIAVPFIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHH
IIFAIVFASLFFNADTFYPALGAIVWTLIFGLYSHFKKI
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEDIQKNHEAQRGLQNRHIQLIAIAGTIGTGLFLGAGKTIQMTGPSVIFAYILIGIAMFF
CCCHHHHHHHHCCHHHCCEEEEEEECHHHHHHEECCCCEEEECCHHHHHHHHHHHHHHHH
FLRTIGEMLYNDPSQHSFLNFVTKYSGIRTGYFTQWSYWLVIVFVCISELTAIGTYIQFW
HHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPHLPLWLIEIVMLALLFGLNTLNSRFFGETEFWFAMIKVAAILGMIVTAIILVASNFHY
HHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
TTVLSGKTVNDTASLNNIFDGFQLFPHGAWNFVGALQMVMFAFTSMEFIGMTAAETVNPK
EEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCH
KSLPKAINQIPVRILLFYVGALLAIMAIFNWHYIPADKSPFVIVFQLIGIKWAAALINFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VLTSAASALNSSLFSATRNMYSLAKQHDKGRLTAFTKLSKAGIPINALYMATALSLLAPV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LTLIPQIKNAFNFAASCTTNLFLVVYFITLYTYWQYRKSDDYNPNGFLTPKPTIAVPFIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHH
IIFAIVFASLFFNADTFYPALGAIVWTLIFGLYSHFKKI
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-glycine [Periplasm]; D-alanine [Periplasm]; Proton [Periplasm]; D-serine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + D-glycine [Periplasm] = Proton [Cytoplasm] + D-glycine [Cytoplasm] Proton [Periplasm] + D-alanine [Periplasm] = Proton [Cytoplasm] + D-alanine [Cytoplasm] Proton [Periplasm] + D-serine [Periplasm] = Proton [Cytoplasm] + D-serine [Cyto

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]