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The map label for this gene is ydgF [H]

Identifier: 125623244

GI number: 125623244

Start: 367634

End: 369016

Strand: Reverse

Name: ydgF [H]

Synonym: llmg_0375

Alternate gene names: 125623244

Gene position: 369016-367634 (Counterclockwise)

Preceding gene: 125623245

Following gene: 125623239

Centisome position: 14.59

GC content: 34.78

Gene sequence:

>1383_bases
ATGAATACAAATCAAAATGATGAAAACATAGAAAAACAGCCTTCTCAACGTGGTTTAAAAAATAGGCATATTCAACTGAT
TGCGATTGCGGGAACAATCGGTACCGGACTTTTCCTTGGAGCCGGAAAATCAATTCATCTTACTGGTCCTTCGATTATTT
TTGTTTATTTGATTATCGGAGCTCTGATGTACATCCTATTAAGAGCAATTGGAGAGATGCTTTATCAAGATCCTAGTCAG
CATTCCTTTTTGAACTTTGTCTCACGATATATGGGAGCCAAACCTGGATATTTTATTCAGTGGTCTTATTTGCTAGTCGT
TGTTTTTGTCGCGATGGCCGAACTAATTGCCATCGGAACTTATATTAATTTTTGGTTGCCAGATTTACCGATTTGGATGA
CTGAGGTTTTTGTTTTAGTTCTTTTAACACTATTAAATACTTTAAATCCTAAATTCTTCGGTGAAACAGAATTTTGGTTT
GGAATGATTAAAATTGTTGCCATCATTGGTTTGATATTAACTGCAATTATTTTAATTTTTAGCCACTATCATACGGGAAC
TGACACGGTTAGTTTAACGAACATCACTAAAGGCTTTGAGTTCTTCCCTAACGGCGTCTCTAGTTTCTTTGAAAGCTTTC
AAATGGTAATGTTTGCCTTTGTTTCTATGGAATTCATAGGGATGACTGCGGCTGAAACGGACAATCCAAGGCCTACTTTG
AAAAAAGCTATTAATCAAATTCCAATTAGAATTGTACTCTTTTATATTGGGGCTCTACTTGCCATTATGAGTATTTATCA
ATGGCGAGATATTCCTGCTGATAAATCTCCATTTGTCACCATTTTCCAATTAATTGGTATCAAATGGGCTGCCGCTTTGG
TTAATTTCGTTGTTTTAACCTCTGCTGCTTCTGCCTTGAACTCCGCTCTCTTTTCAATCACGCGAAATCTCTACTCATTA
TCGCAACTTAATGATGATAAAATTCTTAAGCCATTTACAAAATTCTCAAAAGCTGGTGTCCCCGTAAATGCGTTACTTTT
CACATCACTATTGATTTTATTTACTCCATTTATTTCAATGATTCCAGCAATCTCTAATTCCTTTGTCTTTATTACCAGTG
TCGCAACAAATCTTTTTCTAGTCGTCTATCTGATGACTTTAATCACTTATCTAAAATATCGCAAATCAAAAGATTTTGAT
CCAAGTGGCTTTACTTTACCAGCGGCTCATATCTTTATTCCATTAGCTATTGCTGGATTTGTATTAATCTTTATTTCACT
TTTCTGCTTTAAAGATACAATTATTCCGGCCATTGGTTCTGTGATTTGGGTTCTTATCTTTGGATTATTTACCTTCTTTA
GAAAAATAAAAACAGCTGATTAA

Upstream 100 bases:

>100_bases
GGCTTTACTCCCATTTCAAAAAAATCTAATTCAGGTTCACTCCTTTATAAAATAGAGCAGTCTCTGAAAATCTTAATGAA
AAAGCGTATAATATTATATT

Downstream 100 bases:

>100_bases
TTCAGCTGCTTTTTTTTAATCTTCAAGTTCAAGTTCGATTTCTTCTGTTTCTACTGCTTTTTCTTCTTTTTTAGCTTTTG
CTTTAGTTTTTGAAGCTGTA

Product: amino acid permease

Products: D-glycine [Cytoplasm]; D-alanine [Cytoplasm]; Proton [Cytoplasm]; D-serine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MNTNQNDENIEKQPSQRGLKNRHIQLIAIAGTIGTGLFLGAGKSIHLTGPSIIFVYLIIGALMYILLRAIGEMLYQDPSQ
HSFLNFVSRYMGAKPGYFIQWSYLLVVVFVAMAELIAIGTYINFWLPDLPIWMTEVFVLVLLTLLNTLNPKFFGETEFWF
GMIKIVAIIGLILTAIILIFSHYHTGTDTVSLTNITKGFEFFPNGVSSFFESFQMVMFAFVSMEFIGMTAAETDNPRPTL
KKAINQIPIRIVLFYIGALLAIMSIYQWRDIPADKSPFVTIFQLIGIKWAAALVNFVVLTSAASALNSALFSITRNLYSL
SQLNDDKILKPFTKFSKAGVPVNALLFTSLLILFTPFISMIPAISNSFVFITSVATNLFLVVYLMTLITYLKYRKSKDFD
PSGFTLPAAHIFIPLAIAGFVLIFISLFCFKDTIIPAIGSVIWVLIFGLFTFFRKIKTAD

Sequences:

>Translated_460_residues
MNTNQNDENIEKQPSQRGLKNRHIQLIAIAGTIGTGLFLGAGKSIHLTGPSIIFVYLIIGALMYILLRAIGEMLYQDPSQ
HSFLNFVSRYMGAKPGYFIQWSYLLVVVFVAMAELIAIGTYINFWLPDLPIWMTEVFVLVLLTLLNTLNPKFFGETEFWF
GMIKIVAIIGLILTAIILIFSHYHTGTDTVSLTNITKGFEFFPNGVSSFFESFQMVMFAFVSMEFIGMTAAETDNPRPTL
KKAINQIPIRIVLFYIGALLAIMSIYQWRDIPADKSPFVTIFQLIGIKWAAALVNFVVLTSAASALNSALFSITRNLYSL
SQLNDDKILKPFTKFSKAGVPVNALLFTSLLILFTPFISMIPAISNSFVFITSVATNLFLVVYLMTLITYLKYRKSKDFD
PSGFTLPAAHIFIPLAIAGFVLIFISLFCFKDTIIPAIGSVIWVLIFGLFTFFRKIKTAD
>Mature_460_residues
MNTNQNDENIEKQPSQRGLKNRHIQLIAIAGTIGTGLFLGAGKSIHLTGPSIIFVYLIIGALMYILLRAIGEMLYQDPSQ
HSFLNFVSRYMGAKPGYFIQWSYLLVVVFVAMAELIAIGTYINFWLPDLPIWMTEVFVLVLLTLLNTLNPKFFGETEFWF
GMIKIVAIIGLILTAIILIFSHYHTGTDTVSLTNITKGFEFFPNGVSSFFESFQMVMFAFVSMEFIGMTAAETDNPRPTL
KKAINQIPIRIVLFYIGALLAIMSIYQWRDIPADKSPFVTIFQLIGIKWAAALVNFVVLTSAASALNSALFSITRNLYSL
SQLNDDKILKPFTKFSKAGVPVNALLFTSLLILFTPFISMIPAISNSFVFITSVATNLFLVVYLMTLITYLKYRKSKDFD
PSGFTLPAAHIFIPLAIAGFVLIFISLFCFKDTIIPAIGSVIWVLIFGLFTFFRKIKTAD

Specific function: Probable amino-acid or metabolite transport protein [H]

COG id: COG1113

COG function: function code E; Gamma-aminobutyrate permease and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1790653, Length=460, Percent_Identity=41.7391304347826, Blast_Score=355, Evalue=3e-99,
Organism=Escherichia coli, GI1786302, Length=465, Percent_Identity=35.0537634408602, Blast_Score=288, Evalue=6e-79,
Organism=Escherichia coli, GI1786789, Length=468, Percent_Identity=34.1880341880342, Blast_Score=284, Evalue=8e-78,
Organism=Escherichia coli, GI48994972, Length=428, Percent_Identity=34.5794392523364, Blast_Score=272, Evalue=3e-74,
Organism=Escherichia coli, GI1786602, Length=451, Percent_Identity=34.1463414634146, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI87081915, Length=426, Percent_Identity=32.3943661971831, Blast_Score=232, Evalue=5e-62,
Organism=Escherichia coli, GI87081708, Length=451, Percent_Identity=31.0421286031042, Blast_Score=215, Evalue=5e-57,
Organism=Escherichia coli, GI1788480, Length=433, Percent_Identity=30.4849884526559, Blast_Score=198, Evalue=5e-52,
Organism=Escherichia coli, GI1789017, Length=389, Percent_Identity=29.305912596401, Blast_Score=189, Evalue=3e-49,
Organism=Saccharomyces cerevisiae, GI6324924, Length=440, Percent_Identity=30.6818181818182, Blast_Score=179, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6320772, Length=436, Percent_Identity=30.045871559633, Blast_Score=154, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6324061, Length=420, Percent_Identity=28.0952380952381, Blast_Score=154, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6322892, Length=408, Percent_Identity=28.6764705882353, Blast_Score=151, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6324990, Length=450, Percent_Identity=30.6666666666667, Blast_Score=148, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6319608, Length=410, Percent_Identity=25.3658536585366, Blast_Score=133, Evalue=6e-32,
Organism=Saccharomyces cerevisiae, GI6321629, Length=418, Percent_Identity=24.1626794258373, Blast_Score=126, Evalue=9e-30,
Organism=Saccharomyces cerevisiae, GI6321053, Length=415, Percent_Identity=24.8192771084337, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6324553, Length=402, Percent_Identity=26.865671641791, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6324059, Length=366, Percent_Identity=31.4207650273224, Blast_Score=119, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6319824, Length=426, Percent_Identity=25.5868544600939, Blast_Score=109, Evalue=9e-25,
Organism=Saccharomyces cerevisiae, GI6320717, Length=419, Percent_Identity=23.6276849642005, Blast_Score=106, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6322967, Length=328, Percent_Identity=27.4390243902439, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6319542, Length=421, Percent_Identity=24.7030878859857, Blast_Score=98, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6320251, Length=409, Percent_Identity=22.7383863080685, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6319543, Length=418, Percent_Identity=23.9234449760766, Blast_Score=91, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6324981, Length=338, Percent_Identity=26.3313609467456, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6320364, Length=494, Percent_Identity=22.8744939271255, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 51524; Mature: 51524

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTNQNDENIEKQPSQRGLKNRHIQLIAIAGTIGTGLFLGAGKSIHLTGPSIIFVYLIIG
CCCCCCCCHHHCCHHHCCCCCCCEEEEEEECHHHHHHHEECCCEEEECCHHHHHHHHHHH
ALMYILLRAIGEMLYQDPSQHSFLNFVSRYMGAKPGYFIQWSYLLVVVFVAMAELIAIGT
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHH
YINFWLPDLPIWMTEVFVLVLLTLLNTLNPKFFGETEFWFGMIKIVAIIGLILTAIILIF
HHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SHYHTGTDTVSLTNITKGFEFFPNGVSSFFESFQMVMFAFVSMEFIGMTAAETDNPRPTL
HHCCCCCCCEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
KKAINQIPIRIVLFYIGALLAIMSIYQWRDIPADKSPFVTIFQLIGIKWAAALVNFVVLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SAASALNSALFSITRNLYSLSQLNDDKILKPFTKFSKAGVPVNALLFTSLLILFTPFISM
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
IPAISNSFVFITSVATNLFLVVYLMTLITYLKYRKSKDFDPSGFTLPAAHIFIPLAIAGF
HHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
VLIFISLFCFKDTIIPAIGSVIWVLIFGLFTFFRKIKTAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNTNQNDENIEKQPSQRGLKNRHIQLIAIAGTIGTGLFLGAGKSIHLTGPSIIFVYLIIG
CCCCCCCCHHHCCHHHCCCCCCCEEEEEEECHHHHHHHEECCCEEEECCHHHHHHHHHHH
ALMYILLRAIGEMLYQDPSQHSFLNFVSRYMGAKPGYFIQWSYLLVVVFVAMAELIAIGT
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHH
YINFWLPDLPIWMTEVFVLVLLTLLNTLNPKFFGETEFWFGMIKIVAIIGLILTAIILIF
HHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SHYHTGTDTVSLTNITKGFEFFPNGVSSFFESFQMVMFAFVSMEFIGMTAAETDNPRPTL
HHCCCCCCCEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
KKAINQIPIRIVLFYIGALLAIMSIYQWRDIPADKSPFVTIFQLIGIKWAAALVNFVVLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SAASALNSALFSITRNLYSLSQLNDDKILKPFTKFSKAGVPVNALLFTSLLILFTPFISM
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
IPAISNSFVFITSVATNLFLVVYLMTLITYLKYRKSKDFDPSGFTLPAAHIFIPLAIAGF
HHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
VLIFISLFCFKDTIIPAIGSVIWVLIFGLFTFFRKIKTAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-glycine [Periplasm]; D-alanine [Periplasm]; Proton [Periplasm]; D-serine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + D-glycine [Periplasm] = Proton [Cytoplasm] + D-glycine [Cytoplasm] Proton [Periplasm] + D-alanine [Periplasm] = Proton [Cytoplasm] + D-alanine [Cytoplasm] Proton [Periplasm] + D-serine [Periplasm] = Proton [Cytoplasm] + D-serine [Cyto

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]