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The map label for this gene is add [H]

Identifier: 125623171

GI number: 125623171

Start: 289175

End: 290209

Strand: Direct

Name: add [H]

Synonym: llmg_0299

Alternate gene names: 125623171

Gene position: 289175-290209 (Clockwise)

Preceding gene: 125623170

Following gene: 125623176

Centisome position: 11.43

GC content: 35.17

Gene sequence:

>1035_bases
GTGCTTAAATCAGAAATTATTGCTCAAATGCCAAAAGTTGAACTTCACTGCCATTTAGATGGCTCGCTAAGCTTGTCTTG
TATCAAAGAACTCGCTAAAAATGCCGGCGTGAATATAACGATGACCGATGAGGAGATTTTGGAAAAGGCACAAGCCCCAG
AAAATACCAAAAATTTACTGGAATATCTAAAACGTTTTGATTTTGTTCTGCCTCTTTTACAAAGCTATACAAATCTTGAA
TTGGCGGCCTATGATGTTGTTAAACAGGCAGCTGATGATCATATCAAATATATTGAGATTCGCTTTGCTCCAAGTCAACA
TTTATTAGAAAATCTAAGTCTAGAAGAAGCGGTGGAAGCCGTTATAGCTGGTCTTTCTCGTGCCGAAAATGATTTTGATA
TAAGAGCTAATGCACTCATTTGTGGATTAAAACAAGAACCAATTCAAAAGTTACAAAAACTTCTGCCTCTTTTTGCTAAA
ATTCCTGATGAACACCTTGTCGGATTTGATATGGCAGGAGATGAATTGAATTATCCACAAGAAAAATTTATTGATTTGAT
TCATGATTTAAAAATTAATGGTGTAAATGTGACGCTTCATGCTGGAGAATGTCCATCATGTGAGCAAAATATTTTAGATT
CAATCGCCATGGGGGCAAGTCGGATTGGTCATGGGATTATGACCAAAAATCTATCCAAAGCCGAACAAGAAATGATGATT
GAAAAACAAATTGTTTTAGAGATGGCGCCTACGAGTAATTTTCAAACAAAAGCTGTGACGGAGCTTGCACAATATCCTTT
TAAGGAACTGTATGATAAAGGGTTTCATGTGACTTTGAACACGGATAATCGGACAGTTTCTGCCACAAGTCTAAATAAAG
AATATGAAAAAATATCAGCTTGGTATCCAGATTTTTCTCTAGCTGATTTTGAAAAAATTAATCATTATGCGATTGATGGA
GCTTCTATAAGCAAGGAAGAAAAAGAACAACTTCATCAAAGCTTTATCAAAGAATACAAAAAAATCTCTGAATAA

Upstream 100 bases:

>100_bases
TAGTAAAAATACATTTTTGAAAGAAATATTCGAGCTTTTGGGCTCGAAATCTTTTATATCATGCTCTAAAAATTGGACGA
AAAAGAAAAGGGAGATACTC

Downstream 100 bases:

>100_bases
TTCAGAGATTTTTTTTATTTTAAATCGCGATTTTCGATGACATCTGCGTGAAGTTCACGATGCTTAAATTTCCAACCAGA
TTCTGTTTTTTCAAAGCTAT

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MLKSEIIAQMPKVELHCHLDGSLSLSCIKELAKNAGVNITMTDEEILEKAQAPENTKNLLEYLKRFDFVLPLLQSYTNLE
LAAYDVVKQAADDHIKYIEIRFAPSQHLLENLSLEEAVEAVIAGLSRAENDFDIRANALICGLKQEPIQKLQKLLPLFAK
IPDEHLVGFDMAGDELNYPQEKFIDLIHDLKINGVNVTLHAGECPSCEQNILDSIAMGASRIGHGIMTKNLSKAEQEMMI
EKQIVLEMAPTSNFQTKAVTELAQYPFKELYDKGFHVTLNTDNRTVSATSLNKEYEKISAWYPDFSLADFEKINHYAIDG
ASISKEEKEQLHQSFIKEYKKISE

Sequences:

>Translated_344_residues
MLKSEIIAQMPKVELHCHLDGSLSLSCIKELAKNAGVNITMTDEEILEKAQAPENTKNLLEYLKRFDFVLPLLQSYTNLE
LAAYDVVKQAADDHIKYIEIRFAPSQHLLENLSLEEAVEAVIAGLSRAENDFDIRANALICGLKQEPIQKLQKLLPLFAK
IPDEHLVGFDMAGDELNYPQEKFIDLIHDLKINGVNVTLHAGECPSCEQNILDSIAMGASRIGHGIMTKNLSKAEQEMMI
EKQIVLEMAPTSNFQTKAVTELAQYPFKELYDKGFHVTLNTDNRTVSATSLNKEYEKISAWYPDFSLADFEKINHYAIDG
ASISKEEKEQLHQSFIKEYKKISE
>Mature_344_residues
MLKSEIIAQMPKVELHCHLDGSLSLSCIKELAKNAGVNITMTDEEILEKAQAPENTKNLLEYLKRFDFVLPLLQSYTNLE
LAAYDVVKQAADDHIKYIEIRFAPSQHLLENLSLEEAVEAVIAGLSRAENDFDIRANALICGLKQEPIQKLQKLLPLFAK
IPDEHLVGFDMAGDELNYPQEKFIDLIHDLKINGVNVTLHAGECPSCEQNILDSIAMGASRIGHGIMTKNLSKAEQEMMI
EKQIVLEMAPTSNFQTKAVTELAQYPFKELYDKGFHVTLNTDNRTVSATSLNKEYEKISAWYPDFSLADFEKINHYAIDG
ASISKEEKEQLHQSFIKEYKKISE

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=348, Percent_Identity=25.5747126436782, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI226693318, Length=305, Percent_Identity=25.9016393442623, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI61175224, Length=231, Percent_Identity=27.7056277056277, Blast_Score=82, Evalue=8e-16,
Organism=Escherichia coli, GI1787910, Length=330, Percent_Identity=29.3939393939394, Blast_Score=135, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI32565969, Length=303, Percent_Identity=26.4026402640264, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17538512, Length=303, Percent_Identity=26.4026402640264, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI115537133, Length=334, Percent_Identity=24.5508982035928, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6324188, Length=347, Percent_Identity=23.342939481268, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24645260, Length=297, Percent_Identity=23.5690235690236, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 38847; Mature: 38847

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKSEIIAQMPKVELHCHLDGSLSLSCIKELAKNAGVNITMTDEEILEKAQAPENTKNLL
CCCHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEECHHHHHHHHCCCCCHHHHH
EYLKRFDFVLPLLQSYTNLELAAYDVVKQAADDHIKYIEIRFAPSQHLLENLSLEEAVEA
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEEECCHHHHHHCCCHHHHHHH
VIAGLSRAENDFDIRANALICGLKQEPIQKLQKLLPLFAKIPDEHLVGFDMAGDELNYPQ
HHHHHHHCCCCCCEEECCEEECCCHHHHHHHHHHHHHHHHCCHHHEEECCCCCCCCCCCH
EKFIDLIHDLKINGVNVTLHAGECPSCEQNILDSIAMGASRIGHGIMTKNLSKAEQEMMI
HHHHHHHHHCEECCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHH
EKQIVLEMAPTSNFQTKAVTELAQYPFKELYDKGFHVTLNTDNRTVSATSLNKEYEKISA
HHHHHHEECCCCCCHHHHHHHHHHCCHHHHHCCCCEEEECCCCCEEEHHHHHHHHHHHHH
WYPDFSLADFEKINHYAIDGASISKEEKEQLHQSFIKEYKKISE
CCCCCCHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLKSEIIAQMPKVELHCHLDGSLSLSCIKELAKNAGVNITMTDEEILEKAQAPENTKNLL
CCCHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEECHHHHHHHHCCCCCHHHHH
EYLKRFDFVLPLLQSYTNLELAAYDVVKQAADDHIKYIEIRFAPSQHLLENLSLEEAVEA
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEEECCHHHHHHCCCHHHHHHH
VIAGLSRAENDFDIRANALICGLKQEPIQKLQKLLPLFAKIPDEHLVGFDMAGDELNYPQ
HHHHHHHCCCCCCEEECCEEECCCHHHHHHHHHHHHHHHHCCHHHEEECCCCCCCCCCCH
EKFIDLIHDLKINGVNVTLHAGECPSCEQNILDSIAMGASRIGHGIMTKNLSKAEQEMMI
HHHHHHHHHCEECCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHH
EKQIVLEMAPTSNFQTKAVTELAQYPFKELYDKGFHVTLNTDNRTVSATSLNKEYEKISA
HHHHHHEECCCCCCHHHHHHHHHHCCHHHHHCCCCEEEECCCCCEEEHHHHHHHHHHHHH
WYPDFSLADFEKINHYAIDGASISKEEKEQLHQSFIKEYKKISE
CCCCCCHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]