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The map label for this gene is hipO1

Identifier: 125623164

GI number: 125623164

Start: 280504

End: 281634

Strand: Direct

Name: hipO1

Synonym: llmg_0292

Alternate gene names: 125623164

Gene position: 280504-281634 (Clockwise)

Preceding gene: 125623163

Following gene: 125623165

Centisome position: 11.09

GC content: 38.2

Gene sequence:

>1131_bases
ATGATAAATTTAATCGAAATCCGACGCCAACTTCACCAAATTCCCGAAATTGGACTTGAAGAACATAAAACTCAAAAATA
TTTATTGACGATCATTCATCAAATTATTCAAAATAAATCTTTTATTCAAGTTGAAACTTGGCAAACTGGTCTTTTGGTAT
ATTTGAAAGGGAGTCAAGGCCAAAAAACAATTGGCTGGCGCACAGATATTGACGGACTTCCTGTTGAAGAATTGACTAAT
TTACCATTTGCTAGTAAAAATGGACGAATGCATGCTTGTGGACATGATATTCACATGACTGTTGCTCTTGGTTTACTTGA
AAAATTGAGTGAAAGTCAGCCTAAGAATAATCTTCTTTTTCTTTTTCAACCTGCGGAGGAAAATGAAGCAGGGGGAAAAC
TGATGTATGATGGTGGAGCCTTTAAGAATTGGCTCCCCGATGAATTTTACGGATTACATGTTAGACCTGACTTAAAAGTA
GGAGATATTGCCACTAATGAACAGACTCTTTTTGCTGGAACTTGTGAAGTTGAGTTGACTTTCGTTGGGACAGGAGGACA
TGCTGCTTTTCCGCATACGGCAAATGATGCACTCGTTGCTGCCGCCTATTTCGTCACTCAAGTTCAGACGATTGTGAGCC
GTAATGTTGACCCCTTAGATTCAGCAGTGGTAACATTCGGAAAAATGGAGGCCGGAACAACCAATAATATTATTGCTGAA
CGTGCCTTTTTGCATGGGACCATTCGGAGTTTGACCCAAGAAGTCAATGAATTGACTCAAAAACGTTTGACCGAACTTGC
CAAGGGTGTTGCTCAATCTTTTGATATGACCATTGATTTAAAACTCAAACAAGGAGGTTATCTTCCTGTTGAAAATAATC
CTAAACTGGCAAAAGAACTCATGGATTTTTTTAGAAATGAAACAAAAGCAAATCTGATTGATATTGCACCGGCAATGACT
GGTGAAGATTTTGGTTATCTGTTGAGTAAGATTCCTGGGGTCATGTTTTGGCTTGGGATTAACAGTGAAGCTCCTTTACA
TTCTCAAAAAATGCAAGCTGATGAAGGAGTGCTTGATTTTGCTGTAGAAGCCATTGGTCAATTTTTAGATATTAAAGCAA
ATAGGAACTAA

Upstream 100 bases:

>100_bases
TTTAACAAAAGTTTTTTTGATAAAAGTAGAAATTCACAGGAAAAAAAGAGTAAAATAAATAAAAAAACTTTTGAAATTTA
GCTTAGTAATGAGGACAAAT

Downstream 100 bases:

>100_bases
TAATATCTGATTTTTTCACAAAAAAATAAATTAACGACTTTAATATTGAATAGGGATATGTTATTATAGAAAGATAGAAG
TTAAAATAACATTTTTGTAT

Product: putative hippurate hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MINLIEIRRQLHQIPEIGLEEHKTQKYLLTIIHQIIQNKSFIQVETWQTGLLVYLKGSQGQKTIGWRTDIDGLPVEELTN
LPFASKNGRMHACGHDIHMTVALGLLEKLSESQPKNNLLFLFQPAEENEAGGKLMYDGGAFKNWLPDEFYGLHVRPDLKV
GDIATNEQTLFAGTCEVELTFVGTGGHAAFPHTANDALVAAAYFVTQVQTIVSRNVDPLDSAVVTFGKMEAGTTNNIIAE
RAFLHGTIRSLTQEVNELTQKRLTELAKGVAQSFDMTIDLKLKQGGYLPVENNPKLAKELMDFFRNETKANLIDIAPAMT
GEDFGYLLSKIPGVMFWLGINSEAPLHSQKMQADEGVLDFAVEAIGQFLDIKANRN

Sequences:

>Translated_376_residues
MINLIEIRRQLHQIPEIGLEEHKTQKYLLTIIHQIIQNKSFIQVETWQTGLLVYLKGSQGQKTIGWRTDIDGLPVEELTN
LPFASKNGRMHACGHDIHMTVALGLLEKLSESQPKNNLLFLFQPAEENEAGGKLMYDGGAFKNWLPDEFYGLHVRPDLKV
GDIATNEQTLFAGTCEVELTFVGTGGHAAFPHTANDALVAAAYFVTQVQTIVSRNVDPLDSAVVTFGKMEAGTTNNIIAE
RAFLHGTIRSLTQEVNELTQKRLTELAKGVAQSFDMTIDLKLKQGGYLPVENNPKLAKELMDFFRNETKANLIDIAPAMT
GEDFGYLLSKIPGVMFWLGINSEAPLHSQKMQADEGVLDFAVEAIGQFLDIKANRN
>Mature_376_residues
MINLIEIRRQLHQIPEIGLEEHKTQKYLLTIIHQIIQNKSFIQVETWQTGLLVYLKGSQGQKTIGWRTDIDGLPVEELTN
LPFASKNGRMHACGHDIHMTVALGLLEKLSESQPKNNLLFLFQPAEENEAGGKLMYDGGAFKNWLPDEFYGLHVRPDLKV
GDIATNEQTLFAGTCEVELTFVGTGGHAAFPHTANDALVAAAYFVTQVQTIVSRNVDPLDSAVVTFGKMEAGTTNNIIAE
RAFLHGTIRSLTQEVNELTQKRLTELAKGVAQSFDMTIDLKLKQGGYLPVENNPKLAKELMDFFRNETKANLIDIAPAMT
GEDFGYLLSKIPGVMFWLGINSEAPLHSQKMQADEGVLDFAVEAIGQFLDIKANRN

Specific function: Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. DapL subfamily

Homologues:

Organism=Escherichia coli, GI87081880, Length=337, Percent_Identity=27.0029673590504, Blast_Score=79, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPL_LACLM (A2RI06)

Other databases:

- EMBL:   AM406671
- RefSeq:   YP_001031647.1
- ProteinModelPortal:   A2RI06
- SMR:   A2RI06
- STRING:   A2RI06
- GeneID:   4798877
- GenomeReviews:   AM406671_GR
- KEGG:   llm:llmg_0292
- eggNOG:   COG1473
- HOGENOM:   HBG708500
- OMA:   RTWQTGI
- ProtClustDB:   CLSK876719
- HAMAP:   MF_01692
- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650
- PIRSF:   PIRSF005962
- TIGRFAMs:   TIGR01891

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20; SSF55031 Peptidase_M20_dimer

EC number: =3.5.1.47

Molecular weight: Translated: 41751; Mature: 41751

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS00758 ARGE_DAPE_CPG2_1; PS00759 ARGE_DAPE_CPG2_2

Important sites: ACT_SITE 69-69 ACT_SITE 127-127

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINLIEIRRQLHQIPEIGLEEHKTQKYLLTIIHQIIQNKSFIQVETWQTGLLVYLKGSQG
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEEECCCC
QKTIGWRTDIDGLPVEELTNLPFASKNGRMHACGHDIHMTVALGLLEKLSESQPKNNLLF
CCCCCCCCCCCCCCHHHHHCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCCCEEE
LFQPAEENEAGGKLMYDGGAFKNWLPDEFYGLHVRPDLKVGDIATNEQTLFAGTCEVELT
EEECCCCCCCCCEEEECCCCCCCCCCCCCEEEEECCCCEECCCCCCCCEEEEEEEEEEEE
FVGTGGHAAFPHTANDALVAAAYFVTQVQTIVSRNVDPLDSAVVTFGKMEAGTTNNIIAE
EEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCHHHH
RAFLHGTIRSLTQEVNELTQKRLTELAKGVAQSFDMTIDLKLKQGGYLPVENNPKLAKEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEECCCCCHHHHHHH
MDFFRNETKANLIDIAPAMTGEDFGYLLSKIPGVMFWLGINSEAPLHSQKMQADEGVLDF
HHHHHCCCCCCEEEECCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCHHHHCCCCCHHHH
AVEAIGQFLDIKANRN
HHHHHHHHEEEECCCC
>Mature Secondary Structure
MINLIEIRRQLHQIPEIGLEEHKTQKYLLTIIHQIIQNKSFIQVETWQTGLLVYLKGSQG
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEEECCCC
QKTIGWRTDIDGLPVEELTNLPFASKNGRMHACGHDIHMTVALGLLEKLSESQPKNNLLF
CCCCCCCCCCCCCCHHHHHCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCCCEEE
LFQPAEENEAGGKLMYDGGAFKNWLPDEFYGLHVRPDLKVGDIATNEQTLFAGTCEVELT
EEECCCCCCCCCEEEECCCCCCCCCCCCCEEEEECCCCEECCCCCCCCEEEEEEEEEEEE
FVGTGGHAAFPHTANDALVAAAYFVTQVQTIVSRNVDPLDSAVVTFGKMEAGTTNNIIAE
EEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCHHHH
RAFLHGTIRSLTQEVNELTQKRLTELAKGVAQSFDMTIDLKLKQGGYLPVENNPKLAKEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEECCCCCHHHHHHH
MDFFRNETKANLIDIAPAMTGEDFGYLLSKIPGVMFWLGINSEAPLHSQKMQADEGVLDF
HHHHHCCCCCCEEEECCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCHHHHCCCCCHHHH
AVEAIGQFLDIKANRN
HHHHHHHHEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA