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The map label for this gene is dapD [H]

Identifier: 125623163

GI number: 125623163

Start: 279596

End: 280366

Strand: Direct

Name: dapD [H]

Synonym: llmg_0291

Alternate gene names: 125623163

Gene position: 279596-280366 (Clockwise)

Preceding gene: 125623162

Following gene: 125623164

Centisome position: 11.05

GC content: 46.56

Gene sequence:

>771_bases
ATGGAAGCACAAAAATTATCCGCCCAAGAAATTATTCAATTTATCGGAAATGCCGAGAAAAAAACAGGTGTCAAAGTCAC
TTTGTCAGGAATGCCAAGTTTTAAGTCAGCCGGTTTTCTTGCGGAAAACGGTCGACCAAACTTTAAGGCGCTTGCCAATA
AAGGCATTCAAGTTTTGGGCGATTTTCACACCCATTACAGTCTTAAAATCATCATTGGCGATTGGCAAGCCGTACGTCCC
TTGCTGGAAGGATTGACTGAGAATAAAGATTACACTATTGAATTTGAAGGCAGAAATTCAGCAGTCCCACTCCTTGATAC
AAGAGCTATCAATGCTCGAATCGAGCCGGGTGCGATTATCCGTGACCAAGTGACGATTGGCGATAATGCGGTCATCATGA
TGGGCGCAATCATCAACATCGGGGCTGAGATTGGCGAAGGGACGATGATTGACATGGGTGCTGTTCTAGGTGGTCGGGCA
ACTGTTGGGAAAAACTCTCATATTGGTGCGGGTGCTGTGCTTGCGGGTGTCATTGAGCCAGCAAGTGCCGAACCAGTTCG
TGTGGGCGACAATGTCCTTGTTGGGGCAAATGCCGTTGTCATTGAAGGTGTCCAAGTCGGCTCAGGCTCAGTCGTTGCTG
CAGGCGCGATTGTCACTCAAGACGTCCCAGAAAATGTTGTGGTTGCTGGTGTCCCTGCTCGAATCATCAAAGAAATTGAT
GAAAAAACAGCGCAAAAAACTGCTTTAGAAGATGCCCTTAGAAATTTGTAA

Upstream 100 bases:

>100_bases
AGGTAAAATGAGTCTGTCAGTAAATTTTTAACTTATTGATTTAGAAAACAAGCCCGTAATAGTCATTTGATGAATAAATG
ACTTTAGAATGGAGTGAAAA

Downstream 100 bases:

>100_bases
ATTACAGGAAATAGATTATTTCTGAACTTTTGTTACTTTTAACAAAAGTTTTTTTGATAAAAGTAGAAATTCACAGGAAA
AAAAGAGTAAAATAAATAAA

Product: 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase

Products: NA

Alternate protein names: Tetrahydrodipicolinate N-acetyltransferase; THP acetyltransferase; Tetrahydropicolinate acetylase [H]

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MEAQKLSAQEIIQFIGNAEKKTGVKVTLSGMPSFKSAGFLAENGRPNFKALANKGIQVLGDFHTHYSLKIIIGDWQAVRP
LLEGLTENKDYTIEFEGRNSAVPLLDTRAINARIEPGAIIRDQVTIGDNAVIMMGAIINIGAEIGEGTMIDMGAVLGGRA
TVGKNSHIGAGAVLAGVIEPASAEPVRVGDNVLVGANAVVIEGVQVGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEID
EKTAQKTALEDALRNL

Sequences:

>Translated_256_residues
MEAQKLSAQEIIQFIGNAEKKTGVKVTLSGMPSFKSAGFLAENGRPNFKALANKGIQVLGDFHTHYSLKIIIGDWQAVRP
LLEGLTENKDYTIEFEGRNSAVPLLDTRAINARIEPGAIIRDQVTIGDNAVIMMGAIINIGAEIGEGTMIDMGAVLGGRA
TVGKNSHIGAGAVLAGVIEPASAEPVRVGDNVLVGANAVVIEGVQVGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEID
EKTAQKTALEDALRNL
>Mature_256_residues
MEAQKLSAQEIIQFIGNAEKKTGVKVTLSGMPSFKSAGFLAENGRPNFKALANKGIQVLGDFHTHYSLKIIIGDWQAVRP
LLEGLTENKDYTIEFEGRNSAVPLLDTRAINARIEPGAIIRDQVTIGDNAVIMMGAIINIGAEIGEGTMIDMGAVLGGRA
TVGKNSHIGAGAVLAGVIEPASAEPVRVGDNVLVGANAVVIEGVQVGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEID
EKTAQKTALEDALRNL

Specific function: Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate [H]

COG id: COG2171

COG function: function code E; Tetrahydrodipicolinate N-succinyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. DapH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786362, Length=171, Percent_Identity=35.0877192982456, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1786537, Length=182, Percent_Identity=29.1208791208791, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786664, Length=56, Percent_Identity=57.1428571428571, Blast_Score=67, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322243, Length=65, Percent_Identity=49.2307692307692, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013710
- InterPro:   IPR018357
- InterPro:   IPR019873
- InterPro:   IPR011004 [H]

Pfam domain/function: PF08503 DapD_N [H]

EC number: =2.3.1.89 [H]

Molecular weight: Translated: 26668; Mature: 26668

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAQKLSAQEIIQFIGNAEKKTGVKVTLSGMPSFKSAGFLAENGRPNFKALANKGIQVLG
CCCHHCCHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCEEECCCCCCHHHHHHCCEEEEE
DFHTHYSLKIIIGDWQAVRPLLEGLTENKDYTIEFEGRNSAVPLLDTRAINARIEPGAII
ECCCEEEEEEEEECHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEECEEECCEECCCCEE
RDQVTIGDNAVIMMGAIINIGAEIGEGTMIDMGAVLGGRATVGKNSHIGAGAVLAGVIEP
EEEEEECCCEEEEEEHHHHCCCCCCCCEEEEECHHCCCCEECCCCCCCCCHHHHHHHCCC
ASAEPVRVGDNVLVGANAVVIEGVQVGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEID
CCCCCEEECCEEEECCCEEEEEEEEECCCCEEEECEEEECCCCCCEEEECCCHHHHHHHH
EKTAQKTALEDALRNL
HHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEAQKLSAQEIIQFIGNAEKKTGVKVTLSGMPSFKSAGFLAENGRPNFKALANKGIQVLG
CCCHHCCHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCEEECCCCCCHHHHHHCCEEEEE
DFHTHYSLKIIIGDWQAVRPLLEGLTENKDYTIEFEGRNSAVPLLDTRAINARIEPGAII
ECCCEEEEEEEEECHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEECEEECCEECCCCEE
RDQVTIGDNAVIMMGAIINIGAEIGEGTMIDMGAVLGGRATVGKNSHIGAGAVLAGVIEP
EEEEEECCCEEEEEEHHHHCCCCCCCCEEEEECHHCCCCEECCCCCCCCCHHHHHHHCCC
ASAEPVRVGDNVLVGANAVVIEGVQVGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEID
CCCCCEEECCEEEECCCEEEEEEEEECCCCEEEECEEEECCCCCCEEEECCCHHHHHHHH
EKTAQKTALEDALRNL
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA