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The map label for this gene is rmlC [H]

Identifier: 125623084

GI number: 125623084

Start: 196330

End: 196923

Strand: Direct

Name: rmlC [H]

Synonym: llmg_0207

Alternate gene names: 125623084

Gene position: 196330-196923 (Clockwise)

Preceding gene: 125623083

Following gene: 125623085

Centisome position: 7.76

GC content: 35.86

Gene sequence:

>594_bases
ATGACTGAGAATTTTTTCGGAAAAACACTTGCTAGTCGAGAAATTAGTCAAATTCCAGGAATGTTAGAATTTGATATTCC
GGTTCATGGTGATAATCGTGGTTGGTTTAAAGAAAATTTTCAAAAAGAAAAAATGATGCCTCTTGGTTTTCCAGAAAGTT
TTTTTGCTGAAGAAAAATTGCAAAATAATGTAAGTTTCTCTCGTAAAAATGTTTTGCGTGGGCTTCATGCCGAACCTTGG
GATAAATATATTTCTGTTGCTGATGGTGGCTCTGTTTTGGGTGCATGGGTTGATTTACGCGAAGGCGAAAATTTTGGTCA
TGTTTACCAAACAGTCATTGATGCAAGTAAAGGAATTTTCGTTCCACGCGGCGTGGCTAATGGTTTCCAAGTTTTATCTG
ATACAGTTTCTTATAGCTATCTGGTTAATGATTACTGGGCACTTGAACTTAAACCTAAATATGCTTTTGTAAACTACGCT
GACCCAACATTGGGAATCAAGTGGGAAGATGTTGAAAATGCTGAAGTTTCTGAAGCAGATAAAAATCATCCAATGTTAAA
AGATGTAAAACCTTTAAAGGCTGATGAACTCTAA

Upstream 100 bases:

>100_bases
GCATGGGTTATATCACAGAAGAGGATGTTCGTACTTTGGCACAACCGCTTAAGAAAAATGAATACGGACAATATTTGCTT
CGTTTGATTGGAGATAAATA

Downstream 100 bases:

>100_bases
TGTTTGCTTTACATTTACGAACTAAAAAGCGTTTAGAATTTTGGCAAGTTGAAAAAGACAATGACAGACCAATTTGGGCT
AATCAAGCCTTTACTGACGG

Product: dTDP-4-keto-6-deoxyglucose-3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MTENFFGKTLASREISQIPGMLEFDIPVHGDNRGWFKENFQKEKMMPLGFPESFFAEEKLQNNVSFSRKNVLRGLHAEPW
DKYISVADGGSVLGAWVDLREGENFGHVYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
DPTLGIKWEDVENAEVSEADKNHPMLKDVKPLKADEL

Sequences:

>Translated_197_residues
MTENFFGKTLASREISQIPGMLEFDIPVHGDNRGWFKENFQKEKMMPLGFPESFFAEEKLQNNVSFSRKNVLRGLHAEPW
DKYISVADGGSVLGAWVDLREGENFGHVYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
DPTLGIKWEDVENAEVSEADKNHPMLKDVKPLKADEL
>Mature_196_residues
TENFFGKTLASREISQIPGMLEFDIPVHGDNRGWFKENFQKEKMMPLGFPESFFAEEKLQNNVSFSRKNVLRGLHAEPWD
KYISVADGGSVLGAWVDLREGENFGHVYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYAD
PTLGIKWEDVENAEVSEADKNHPMLKDVKPLKADEL

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=186, Percent_Identity=30.6451612903226, Blast_Score=70, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 22359; Mature: 22228

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00014 ER_TARGET

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTENFFGKTLASREISQIPGMLEFDIPVHGDNRGWFKENFQKEKMMPLGFPESFFAEEKL
CCCCHHHHHHHHHHHHHCCCEEEEECEEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHHH
QNNVSFSRKNVLRGLHAEPWDKYISVADGGSVLGAWVDLREGENFGHVYQTVIDASKGIF
HCCCCHHHHHHHHCCCCCCHHHEEEECCCCCEEEEEEEECCCCCHHHHHHHHHHCCCCEE
VPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYADPTLGIKWEDVENAEVSEAD
ECCCCCHHHHHHHHHHHHEEEECCEEEEEEECCEEEEEECCCCCCEEECCCCCCCCCCCC
KNHPMLKDVKPLKADEL
CCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TENFFGKTLASREISQIPGMLEFDIPVHGDNRGWFKENFQKEKMMPLGFPESFFAEEKL
CCCHHHHHHHHHHHHHCCCEEEEECEEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHHH
QNNVSFSRKNVLRGLHAEPWDKYISVADGGSVLGAWVDLREGENFGHVYQTVIDASKGIF
HCCCCHHHHHHHHCCCCCCHHHEEEECCCCCEEEEEEEECCCCCHHHHHHHHHHCCCCEE
VPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYADPTLGIKWEDVENAEVSEAD
ECCCCCHHHHHHHHHHHHEEEECCEEEEEEECCEEEEEECCCCCCEEECCCCCCCCCCCC
KNHPMLKDVKPLKADEL
CCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA