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The map label for this gene is dtd [H]

Identifier: 125622994

GI number: 125622994

Start: 109228

End: 109683

Strand: Direct

Name: dtd [H]

Synonym: llmg_0115

Alternate gene names: 125622994

Gene position: 109228-109683 (Clockwise)

Preceding gene: 125622992

Following gene: 125622995

Centisome position: 4.32

GC content: 35.09

Gene sequence:

>456_bases
ATGAAAATAGTAATTCAACGAGTAAAGTCAGCTTCTGTCAGTATTGATGGAAAAATTAAAGAAAAGATTAATCAGGGTTT
TTTGCTTTTGGTTGGAGTTGAAGATGCTGACAGCAATTTTGATTTGGACTATGCGGTGCGTAAAATTGCTCAAATGAGAA
TCTTTTCAGATGAAGCTGATAAAATGAATCTCTCTGTTCAAGATATTCAAGGAGAAATATTATCAATTTCTCAGTTTACT
TTGTATGCGGAAACCAAAAAAGGTAATCGTCCGAGCTTTTCTGCGGCAGGAAAACCTGATTTTGCTAAAGCAATGTATGA
AAAATTCAATGACAGTTTAGCTCAGATTGTGCCAGTTAAAGCAGGTGTTTTTGGTGCAGACATGCAAGTTGAATTGATAA
ATGATGGCCCCGTCACGATTATTTTAGATACGAAAGAAGCTAGAAAAAATGCCTAA

Upstream 100 bases:

>100_bases
GATTGACTTAAAAAATCGATTAAAATCAGGTAAATAAAATAGCTTTTTTATGCTATACTGTCAGTAAAGAGATCAACATA
GGAGTGAAACATTAAGTATT

Downstream 100 bases:

>100_bases
AAGATTGCAAAAGAGTAGAGTTAAAAAACAAACTCCTATTCGCTCTGTCAGTAAAACCAAAACTTTTCAAAGCTTAAAAA
AATCTGAGCAGTCTGACCAA

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MKIVIQRVKSASVSIDGKIKEKINQGFLLLVGVEDADSNFDLDYAVRKIAQMRIFSDEADKMNLSVQDIQGEILSISQFT
LYAETKKGNRPSFSAAGKPDFAKAMYEKFNDSLAQIVPVKAGVFGADMQVELINDGPVTIILDTKEARKNA

Sequences:

>Translated_151_residues
MKIVIQRVKSASVSIDGKIKEKINQGFLLLVGVEDADSNFDLDYAVRKIAQMRIFSDEADKMNLSVQDIQGEILSISQFT
LYAETKKGNRPSFSAAGKPDFAKAMYEKFNDSLAQIVPVKAGVFGADMQVELINDGPVTIILDTKEARKNA
>Mature_151_residues
MKIVIQRVKSASVSIDGKIKEKINQGFLLLVGVEDADSNFDLDYAVRKIAQMRIFSDEADKMNLSVQDIQGEILSISQFT
LYAETKKGNRPSFSAAGKPDFAKAMYEKFNDSLAQIVPVKAGVFGADMQVELINDGPVTIILDTKEARKNA

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine [H]

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family [H]

Homologues:

Organism=Homo sapiens, GI30795227, Length=148, Percent_Identity=43.2432432432432, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1790320, Length=143, Percent_Identity=45.4545454545455, Blast_Score=125, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI115533292, Length=150, Percent_Identity=38.6666666666667, Blast_Score=106, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6319982, Length=148, Percent_Identity=45.945945945946, Blast_Score=124, Evalue=6e-30,
Organism=Drosophila melanogaster, GI281361569, Length=151, Percent_Identity=43.7086092715232, Blast_Score=122, Evalue=8e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003732 [H]

Pfam domain/function: PF02580 Tyr_Deacylase [H]

EC number: NA

Molecular weight: Translated: 16633; Mature: 16633

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVIQRVKSASVSIDGKIKEKINQGFLLLVGVEDADSNFDLDYAVRKIAQMRIFSDEAD
CHHEEEECCCCCEEECCHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCC
KMNLSVQDIQGEILSISQFTLYAETKKGNRPSFSAAGKPDFAKAMYEKFNDSLAQIVPVK
CCCCCHHHCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHEEEEC
AGVFGADMQVELINDGPVTIILDTKEARKNA
CCEECCCEEEEEECCCCEEEEEECHHHCCCC
>Mature Secondary Structure
MKIVIQRVKSASVSIDGKIKEKINQGFLLLVGVEDADSNFDLDYAVRKIAQMRIFSDEAD
CHHEEEECCCCCEEECCHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCC
KMNLSVQDIQGEILSISQFTLYAETKKGNRPSFSAAGKPDFAKAMYEKFNDSLAQIVPVK
CCCCCHHHCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHEEEEC
AGVFGADMQVELINDGPVTIILDTKEARKNA
CCEECCCEEEEEECCCCEEEEEECHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]