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The map label for this gene is mtrD [H]

Identifier: 124486374

GI number: 124486374

Start: 1591785

End: 1592648

Strand: Reverse

Name: mtrD [H]

Synonym: Mlab_1559

Alternate gene names: 124486374

Gene position: 1592648-1591785 (Counterclockwise)

Preceding gene: 124486375

Following gene: 124486373

Centisome position: 88.24

GC content: 51.39

Gene sequence:

>864_bases
ATGAGTGCAATCGCAGCTAAACCCGGAGCAAATGCCGGCGCATTCCAGCCAATTCCTTCGGTCATCGCAATCGTTATTGC
AATCATTCTCGTTGTTGCTGCTTACTTCCTTGGAAGTTCCGGCATTCTTGCCGGCGGTGCAATGTTCGTTCTTCAGACTC
TGTGTCTGATCATCCTTGGTGCAGCCTTAATCGCATTTGGTGTTCACTTTGTTCCCGTCGGCGGAGCGCCGGCAGCAATG
GGTCAGGCACCCGGTATTGCTACCGGTGTCGCAATGCTTGCAACAGGTGCAGGTCTTGCAGGACTCTTTGGCGGAGCATG
GGCAGCAGAGTTAGGTATTGGAGTCGCACTTGCCAGTGGAGCAATTGGCGGTGCATTAATGATGGCAATCACCTGTCTTA
TGGTGAACATCTCCTATGTCTTTGGCATGGGTATCCCGGCAGCCTCCGGTAAGGTCGAAAAAGATCCGATCACCGGTGAT
TTACAGGCAGCATACAAATCCCAGGGAACCGAAGGTCACGGTTTACCGTTCATCTCTTATGTTGGCGGTGTTATCGGCGG
TCTTTTCGGTGGTCTTGGCGGAACACTCATCTACATTGAACTTCTCGACTTCTACAATGCTGGTCTTCCAGCACTTGGTT
TTGTTGGAGCAGCAGACATCAATATGCTCTCCGTAGGTCTTGCAGGCATCTTTGCAATCGGTATGTTCCTTGTTATCGCA
GTACTTTCTGCATACAACATTACCGGAACCATCGAAGGTCCGCACGACCCGAAGTTCAAGCGTTTCCCCCGTGCAATCGT
CGCCGCAATCTTAGCTTCAGCTGTGTGCGGTCTTGTTGCAATGCTGGTGGTGGCATTATTCTGA

Upstream 100 bases:

>100_bases
TCGTTGGAGCAGTTGTAATTATTGTCTTCATGATCATCGACCGTTATGTTGAAGTCTGGGCACGCAAGAGCTACGGACCC
TACACTGTGGAGGCCTGAAT

Downstream 100 bases:

>100_bases
GGTGTAAAAAATGTCAGTAAAAGTTGAAGCATCCCACGACGGAATTCCACATGACAAGGTCATGGTCATCGGAGCCGTTA
TTTCACTGGTATCCCTTTAC

Product: tetrahydromethanopterin S-methyltransferase subunit D

Products: NA

Alternate protein names: N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit D [H]

Number of amino acids: Translated: 287; Mature: 286

Protein sequence:

>287_residues
MSAIAAKPGANAGAFQPIPSVIAIVIAIILVVAAYFLGSSGILAGGAMFVLQTLCLIILGAALIAFGVHFVPVGGAPAAM
GQAPGIATGVAMLATGAGLAGLFGGAWAAELGIGVALASGAIGGALMMAITCLMVNISYVFGMGIPAASGKVEKDPITGD
LQAAYKSQGTEGHGLPFISYVGGVIGGLFGGLGGTLIYIELLDFYNAGLPALGFVGAADINMLSVGLAGIFAIGMFLVIA
VLSAYNITGTIEGPHDPKFKRFPRAIVAAILASAVCGLVAMLVVALF

Sequences:

>Translated_287_residues
MSAIAAKPGANAGAFQPIPSVIAIVIAIILVVAAYFLGSSGILAGGAMFVLQTLCLIILGAALIAFGVHFVPVGGAPAAM
GQAPGIATGVAMLATGAGLAGLFGGAWAAELGIGVALASGAIGGALMMAITCLMVNISYVFGMGIPAASGKVEKDPITGD
LQAAYKSQGTEGHGLPFISYVGGVIGGLFGGLGGTLIYIELLDFYNAGLPALGFVGAADINMLSVGLAGIFAIGMFLVIA
VLSAYNITGTIEGPHDPKFKRFPRAIVAAILASAVCGLVAMLVVALF
>Mature_286_residues
SAIAAKPGANAGAFQPIPSVIAIVIAIILVVAAYFLGSSGILAGGAMFVLQTLCLIILGAALIAFGVHFVPVGGAPAAMG
QAPGIATGVAMLATGAGLAGLFGGAWAAELGIGVALASGAIGGALMMAITCLMVNISYVFGMGIPAASGKVEKDPITGDL
QAAYKSQGTEGHGLPFISYVGGVIGGLFGGLGGTLIYIELLDFYNAGLPALGFVGAADINMLSVGLAGIFAIGMFLVIAV
LSAYNITGTIEGPHDPKFKRFPRAIVAAILASAVCGLVAMLVVALF

Specific function: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step [H]

COG id: COG4060

COG function: function code H; Tetrahydromethanopterin S-methyltransferase, subunit D

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mtrD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005779
- ProDom:   PD013594 [H]

Pfam domain/function: PF04207 MtrD [H]

EC number: =2.1.1.86 [H]

Molecular weight: Translated: 28298; Mature: 28167

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAIAAKPGANAGAFQPIPSVIAIVIAIILVVAAYFLGSSGILAGGAMFVLQTLCLIILG
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
AALIAFGVHFVPVGGAPAAMGQAPGIATGVAMLATGAGLAGLFGGAWAAELGIGVALASG
HHHHHHHHHHEECCCCCHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
AIGGALMMAITCLMVNISYVFGMGIPAASGKVEKDPITGDLQAAYKSQGTEGHGLPFISY
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHH
VGGVIGGLFGGLGGTLIYIELLDFYNAGLPALGFVGAADINMLSVGLAGIFAIGMFLVIA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
VLSAYNITGTIEGPHDPKFKRFPRAIVAAILASAVCGLVAMLVVALF
HHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
SAIAAKPGANAGAFQPIPSVIAIVIAIILVVAAYFLGSSGILAGGAMFVLQTLCLIILG
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
AALIAFGVHFVPVGGAPAAMGQAPGIATGVAMLATGAGLAGLFGGAWAAELGIGVALASG
HHHHHHHHHHEECCCCCHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
AIGGALMMAITCLMVNISYVFGMGIPAASGKVEKDPITGDLQAAYKSQGTEGHGLPFISY
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHH
VGGVIGGLFGGLGGTLIYIELLDFYNAGLPALGFVGAADINMLSVGLAGIFAIGMFLVIA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
VLSAYNITGTIEGPHDPKFKRFPRAIVAAILASAVCGLVAMLVVALF
HHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9559648; 12125824; 8774736 [H]