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The map label for this gene is tpiA

Identifier: 124485992

GI number: 124485992

Start: 1195222

End: 1195887

Strand: Reverse

Name: tpiA

Synonym: Mlab_1172

Alternate gene names: 124485992

Gene position: 1195887-1195222 (Counterclockwise)

Preceding gene: 124485993

Following gene: 124485989

Centisome position: 66.26

GC content: 58.26

Gene sequence:

>666_bases
ATGTCGTCTCCGCTTATCCTGGTGAACTTCAAGTCATACCGCGAAGGAGCGGGCAATGCGGCAGGACAGATAGCTTCGGC
CGCCGAACTTGTGATGCAGGAGTCGGGCGTGACTATCGGTATCGCTCCGCAGTTTGTGGAGCTTCACCCGTTCTGCAAGC
ATTACGAGATCCCGGTGTATGCCCAGCACATCGATGCGGTGGAAGGAGCTTTCACCGGCCGGATCCCTGCATTCACGGTG
CGGGCGGCCGGCTGTGTTGGGTCGCTGATCAATCACTCGGAACGAAGACTGACGATCGCAGAGATTGAGGCATGCGTCGA
AGCGGCGAAGTTCAATCATCTGGAGTCGGTGGTCTGCACGAACAATGTGGGCGTTTCGGCAGCGGCCGCGGCGTTTTCGC
CGACGTATGTGGCTGTCGAGCCGCCGGAACTTATCGGCTCGGGCATCTCGGTCGCAAAAGCGGATCCCGATATCATCAGA
AATTCGGTTGCTGCAGTGAAAAAGATCAGCTCGGACGTTAAGGTCCTCTGCGGTGCAGGCATCCAGTCGGGCGAGTGCGT
AAAAACGGCGGTCGATCTTGGAGCTGACGGCGTTCTGCTCGCATCCAGCGTCGTGAAGGCAAAGGATCCGGAGGCCGTGC
TTCGCGATCTGGTGTCCCTTTTATAA

Upstream 100 bases:

>100_bases
GCATCGTTCTTCTGGATGTGTCCGATGACGACGACAAGCTTCAGGCAGGCGGCGTCGCATCCACCACGCTCGGCGATGTT
CTTCAGGTGAAGAGGAAGTA

Downstream 100 bases:

>100_bases
TTCCTGAATACTACTCAAATAAGCTCAAATACTTTTTTTTAATAGGACTTACGCGGTGTTAATCCCTCTTCAATTAGGGA
AGAGTATTACTGGGTATGGA

Product: triosephosphate isomerase

Products: NA

Alternate protein names: TIM; Triose-phosphate isomerase

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MSSPLILVNFKSYREGAGNAAGQIASAAELVMQESGVTIGIAPQFVELHPFCKHYEIPVYAQHIDAVEGAFTGRIPAFTV
RAAGCVGSLINHSERRLTIAEIEACVEAAKFNHLESVVCTNNVGVSAAAAAFSPTYVAVEPPELIGSGISVAKADPDIIR
NSVAAVKKISSDVKVLCGAGIQSGECVKTAVDLGADGVLLASSVVKAKDPEAVLRDLVSLL

Sequences:

>Translated_221_residues
MSSPLILVNFKSYREGAGNAAGQIASAAELVMQESGVTIGIAPQFVELHPFCKHYEIPVYAQHIDAVEGAFTGRIPAFTV
RAAGCVGSLINHSERRLTIAEIEACVEAAKFNHLESVVCTNNVGVSAAAAAFSPTYVAVEPPELIGSGISVAKADPDIIR
NSVAAVKKISSDVKVLCGAGIQSGECVKTAVDLGADGVLLASSVVKAKDPEAVLRDLVSLL
>Mature_220_residues
SSPLILVNFKSYREGAGNAAGQIASAAELVMQESGVTIGIAPQFVELHPFCKHYEIPVYAQHIDAVEGAFTGRIPAFTVR
AAGCVGSLINHSERRLTIAEIEACVEAAKFNHLESVVCTNNVGVSAAAAAFSPTYVAVEPPELIGSGISVAKADPDIIRN
SVAAVKKISSDVKVLCGAGIQSGECVKTAVDLGADGVLLASSVVKAKDPEAVLRDLVSLL

Specific function: Unknown

COG id: COG0149

COG function: function code G; Triosephosphate isomerase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the triosephosphate isomerase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TPIS_METLZ (A2SSN5)

Other databases:

- EMBL:   CP000559
- RefSeq:   YP_001030608.1
- ProteinModelPortal:   A2SSN5
- SMR:   A2SSN5
- STRING:   A2SSN5
- GeneID:   4794779
- GenomeReviews:   CP000559_GR
- KEGG:   mla:Mlab_1172
- eggNOG:   arNOG04711
- HOGENOM:   HBG297256
- OMA:   VEPPELI
- ProtClustDB:   PRK04302
- BioCyc:   MLAB410358:MLAB_1172-MONOMER
- GO:   GO:0005737
- GO:   GO:0006094
- GO:   GO:0006096
- HAMAP:   MF_00147_A
- InterPro:   IPR013785
- InterPro:   IPR000652
- InterPro:   IPR022891
- InterPro:   IPR020861
- Gene3D:   G3DSA:3.20.20.70
- TIGRFAMs:   TIGR00419

Pfam domain/function: PF00121 TIM; SSF51351 Triophos_ismrse

EC number: =5.3.1.1

Molecular weight: Translated: 22886; Mature: 22755

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS00171 TIM_1; PS51440 TIM_2

Important sites: ACT_SITE 92-92 ACT_SITE 140-140 BINDING 9-9 BINDING 11-11

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSPLILVNFKSYREGAGNAAGQIASAAELVMQESGVTIGIAPQFVELHPFCKHYEIPVY
CCCCEEEEEEHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEECCCHHHHCHHHHHCCCCHH
AQHIDAVEGAFTGRIPAFTVRAAGCVGSLINHSERRLTIAEIEACVEAAKFNHLESVVCT
HHHHHHHHHHHCCCCCCCEEHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHEEE
NNVGVSAAAAAFSPTYVAVEPPELIGSGISVAKADPDIIRNSVAAVKKISSDVKVLCGAG
CCCCCHHHHHHCCCEEEEECCHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHEEECCC
IQSGECVKTAVDLGADGVLLASSVVKAKDPEAVLRDLVSLL
CCCCHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHC
>Mature Secondary Structure 
SSPLILVNFKSYREGAGNAAGQIASAAELVMQESGVTIGIAPQFVELHPFCKHYEIPVY
CCCEEEEEEHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEECCCHHHHCHHHHHCCCCHH
AQHIDAVEGAFTGRIPAFTVRAAGCVGSLINHSERRLTIAEIEACVEAAKFNHLESVVCT
HHHHHHHHHHHCCCCCCCEEHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHEEE
NNVGVSAAAAAFSPTYVAVEPPELIGSGISVAKADPDIIRNSVAAVKKISSDVKVLCGAG
CCCCCHHHHHHCCCEEEEECCHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHEEECCC
IQSGECVKTAVDLGADGVLLASSVVKAKDPEAVLRDLVSLL
CCCCHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA