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The map label for this gene is hdrA2 [H]

Identifier: 124485800

GI number: 124485800

Start: 976423

End: 977709

Strand: Reverse

Name: hdrA2 [H]

Synonym: Mlab_0979

Alternate gene names: 124485800

Gene position: 977709-976423 (Counterclockwise)

Preceding gene: 124485801

Following gene: 124485799

Centisome position: 54.17

GC content: 56.8

Gene sequence:

>1287_bases
ATGAATAATGTTGTTGTCATTGGCGGAGGAGTCGCCGGCATCCAGAGTGCCATGGACATCGCCAATCACAACATCCATGT
CTATCTGATCGAGCGCGAGCCGTCGATCGGCGGCCACATGGCCATGCTCGACAAAACCTTCCCGACCAACGACTGTTCGA
TGTGCATCCTCTCGCCGAAGATGGCCGAGATCTCCCGGCATCCGAACGTTACGATCCTCACCCTCGCCGAGGTCGAAAAA
ATCGTTGGTGAGGTTGGAAATTTCACCGTCACCGTCACCAAATATCCACGCTACATCAATGAAAAGGAGTGCACGGGCTG
CGGCGACTGTATCACCATCTGCCCGATCGAAGTCTACAACAAATTCGATGCTGGCATCGGGGTTCGAAAAGCGATCTACA
AACCCCACGCCCAGTCGATCCCCAACATCGTTGTAAAAGACAATCTCCACTGTATTGAATGCGGCCTCTGCTACGGGGTC
TGCGGCAAAGACGCCGTCCTCAAAGTCACCGAGGCAAAAGTCGAAACCCTCGAGATCAACGCCTCCGCCGTCGTGATCGC
GACCGGATACTCGCTCTTCGACCCGCAGAAGAAATCCAGATTCGGCTATCTTCGATACCCGGATGTCATCACCTCCCTCG
AATTCGAGCGGATGATCAATGCCGGCGGACCGACCACCGGCAACTTACGCCGGCTCTCGAACGGCGAGACCCCGAAAAGC
ATCGTCTTTGTCCAGTGCGTAGGATCGCGTGACATGACGATCAACAGAAACATCTGTTCCTGCGTATGCTGCATGTACGC
CCTCAAAAACTCCATGCTCATCAAAGAGCATTATCCCGACTGCGAGGTCTCGATCCTCTACTCTGACATCCGGGCCTACG
GAAAAGGCTACGAGGAGTATTACCAGCGGGCGATCGACGCCGGCGTCAAAATCATCCGCGGACTGCCGGGCGATGTGCAG
GACAACGGAAAGGGCCGGCTGGTTCTCCCGGTCGAAAACACCGAGACCGCCGAATTCCTCAATCTGGAAGCCGATCTCGT
TGTCCTTTCGGTCGGCATGATCCCCGAACCGGAAACCGTGCGGCTCGCAAAATCGCTCGGCCTTCCCCTCGACGATCACC
AGTTCTTAAGTCCCGCCGATATGAAACTCGACCCGGCGGGAACGATCCGTCCCGGGATCTACATCGCCGGCGCCGCCCTT
GCTCCAAAAGACATCCCTGACTCGGTCATGTCCGCCGGTGCCGCCGCCATGAAAGCCTCCATCGACGTCGTCAGGAGCGA
ACAGTGA

Upstream 100 bases:

>100_bases
GGCGTTCCAGGAAAAGTCGTTCGCGAACTCACCCCCGAAGAGGCCGCCGGCAACCTCAAAAACGCCGCGACCTACGTCTC
TGTCGGGCAGAGGTATCTCC

Downstream 100 bases:

>100_bases
CCGAGGACAAAACCATCTGGTGGAACGATGAAAACAGTTCCGTGATGCTCATCGACCAGACGCTGCTCCCAACCGAGTAT
AAGGTCATCGAGATCACCGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MNNVVVIGGGVAGIQSAMDIANHNIHVYLIEREPSIGGHMAMLDKTFPTNDCSMCILSPKMAEISRHPNVTILTLAEVEK
IVGEVGNFTVTVTKYPRYINEKECTGCGDCITICPIEVYNKFDAGIGVRKAIYKPHAQSIPNIVVKDNLHCIECGLCYGV
CGKDAVLKVTEAKVETLEINASAVVIATGYSLFDPQKKSRFGYLRYPDVITSLEFERMINAGGPTTGNLRRLSNGETPKS
IVFVQCVGSRDMTINRNICSCVCCMYALKNSMLIKEHYPDCEVSILYSDIRAYGKGYEEYYQRAIDAGVKIIRGLPGDVQ
DNGKGRLVLPVENTETAEFLNLEADLVVLSVGMIPEPETVRLAKSLGLPLDDHQFLSPADMKLDPAGTIRPGIYIAGAAL
APKDIPDSVMSAGAAAMKASIDVVRSEQ

Sequences:

>Translated_428_residues
MNNVVVIGGGVAGIQSAMDIANHNIHVYLIEREPSIGGHMAMLDKTFPTNDCSMCILSPKMAEISRHPNVTILTLAEVEK
IVGEVGNFTVTVTKYPRYINEKECTGCGDCITICPIEVYNKFDAGIGVRKAIYKPHAQSIPNIVVKDNLHCIECGLCYGV
CGKDAVLKVTEAKVETLEINASAVVIATGYSLFDPQKKSRFGYLRYPDVITSLEFERMINAGGPTTGNLRRLSNGETPKS
IVFVQCVGSRDMTINRNICSCVCCMYALKNSMLIKEHYPDCEVSILYSDIRAYGKGYEEYYQRAIDAGVKIIRGLPGDVQ
DNGKGRLVLPVENTETAEFLNLEADLVVLSVGMIPEPETVRLAKSLGLPLDDHQFLSPADMKLDPAGTIRPGIYIAGAAL
APKDIPDSVMSAGAAAMKASIDVVRSEQ
>Mature_428_residues
MNNVVVIGGGVAGIQSAMDIANHNIHVYLIEREPSIGGHMAMLDKTFPTNDCSMCILSPKMAEISRHPNVTILTLAEVEK
IVGEVGNFTVTVTKYPRYINEKECTGCGDCITICPIEVYNKFDAGIGVRKAIYKPHAQSIPNIVVKDNLHCIECGLCYGV
CGKDAVLKVTEAKVETLEINASAVVIATGYSLFDPQKKSRFGYLRYPDVITSLEFERMINAGGPTTGNLRRLSNGETPKS
IVFVQCVGSRDMTINRNICSCVCCMYALKNSMLIKEHYPDCEVSILYSDIRAYGKGYEEYYQRAIDAGVKIIRGLPGDVQ
DNGKGRLVLPVENTETAEFLNLEADLVVLSVGMIPEPETVRLAKSLGLPLDDHQFLSPADMKLDPAGTIRPGIYIAGAAL
APKDIPDSVMSAGAAAMKASIDVVRSEQ

Specific function: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). May act as the catalytic subunit [H]

COG id: COG1148

COG function: function code C; Heterodisulfide reductase, subunit A and related polyferredoxins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 4Fe-4S ferredoxin-type domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR003953
- InterPro:   IPR012285 [H]

Pfam domain/function: PF00890 FAD_binding_2; PF00037 Fer4 [H]

EC number: =1.8.98.1 [H]

Molecular weight: Translated: 46507; Mature: 46507

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNVVVIGGGVAGIQSAMDIANHNIHVYLIEREPSIGGHMAMLDKTFPTNDCSMCILSPK
CCCEEEECCCHHHHHHHHHHHCCCEEEEEEEECCCCCCEEEEEECCCCCCCCCEEEECCH
MAEISRHPNVTILTLAEVEKIVGEVGNFTVTVTKYPRYINEKECTGCGDCITICPIEVYN
HHHHHCCCCEEEEEHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCEEEEEEHHHHH
KFDAGIGVRKAIYKPHAQSIPNIVVKDNLHCIECGLCYGVCGKDAVLKVTEAKVETLEIN
HHCCCCCHHHHHCCCCHHCCCCEEEECCCEEEEEEEEECCCCCCCEEEEEECEEEEEEEC
ASAVVIATGYSLFDPQKKSRFGYLRYPDVITSLEFERMINAGGPTTGNLRRLSNGETPKS
CCEEEEEECCHHCCCCHHCCCCEEECCHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCE
IVFVQCVGSRDMTINRNICSCVCCMYALKNSMLIKEHYPDCEVSILYSDIRAYGKGYEEY
EEEEEEECCCCCEECCCHHHHHHHHHHHHCCEEEEECCCCCEEEEEEHHHHHHCCCHHHH
YQRAIDAGVKIIRGLPGDVQDNGKGRLVLPVENTETAEFLNLEADLVVLSVGMIPEPETV
HHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHEEECCCCEEEEEECCCCCCHHH
RLAKSLGLPLDDHQFLSPADMKLDPAGTIRPGIYIAGAALAPKDIPDSVMSAGAAAMKAS
HHHHHHCCCCCCCCCCCCCCCEECCCCCCCCCEEEEECCCCCCCCCHHHHHCCHHHHHHH
IDVVRSEQ
HEEEECCC
>Mature Secondary Structure
MNNVVVIGGGVAGIQSAMDIANHNIHVYLIEREPSIGGHMAMLDKTFPTNDCSMCILSPK
CCCEEEECCCHHHHHHHHHHHCCCEEEEEEEECCCCCCEEEEEECCCCCCCCCEEEECCH
MAEISRHPNVTILTLAEVEKIVGEVGNFTVTVTKYPRYINEKECTGCGDCITICPIEVYN
HHHHHCCCCEEEEEHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCEEEEEEHHHHH
KFDAGIGVRKAIYKPHAQSIPNIVVKDNLHCIECGLCYGVCGKDAVLKVTEAKVETLEIN
HHCCCCCHHHHHCCCCHHCCCCEEEECCCEEEEEEEEECCCCCCCEEEEEECEEEEEEEC
ASAVVIATGYSLFDPQKKSRFGYLRYPDVITSLEFERMINAGGPTTGNLRRLSNGETPKS
CCEEEEEECCHHCCCCHHCCCCEEECCHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCE
IVFVQCVGSRDMTINRNICSCVCCMYALKNSMLIKEHYPDCEVSILYSDIRAYGKGYEEY
EEEEEEECCCCCEECCCHHHHHHHHHHHHCCEEEEECCCCCEEEEEEHHHHHHCCCHHHH
YQRAIDAGVKIIRGLPGDVQDNGKGRLVLPVENTETAEFLNLEADLVVLSVGMIPEPETV
HHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHEEECCCCEEEEEECCCCCCHHH
RLAKSLGLPLDDHQFLSPADMKLDPAGTIRPGIYIAGAALAPKDIPDSVMSAGAAAMKAS
HHHHHHCCCCCCCCCCCCCCCEECCCCCCCCCEEEEECCCCCCCCCHHHHHCCHHHHHHH
IDVVRSEQ
HEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9063468; 11930014 [H]