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The map label for this gene is fdhB [H]

Identifier: 124485287

GI number: 124485287

Start: 439256

End: 440500

Strand: Reverse

Name: fdhB [H]

Synonym: Mlab_0462

Alternate gene names: 124485287

Gene position: 440500-439256 (Counterclockwise)

Preceding gene: 124485288

Following gene: 124485279

Centisome position: 24.4

GC content: 53.57

Gene sequence:

>1245_bases
ATGTCAGCAAAAGGCGATATGTTCTACGCATGGACTAACGTATCCGATATTAAAGGTGAATGCGGCGGAGCAGTAACCTC
AATTCTCAAGTACCTCCTTGAGAGCAAGACCGTCGACGCAGTACTCACCGTTCAGAAAGGTGCCGATGTCTTCGACGCAG
AACCTGTCGTAATCACCGACCCGGCAGACCTCGTAAAGTCCGCCGGTTCCCTCCACTGCGGAACCCTGTTGTTGCCCAAG
CTCATCAAAAAGTACCTCAACGGTGCAAAAGACATGAAACTTGCCGTCACCTGCAAAGGATGCGACGCAAAAGCAATGTA
CGAGCTTGCAAAACGCCAGCAGATCAACCTCGACAACATCGTCATGATCGGTCTTAACTGCGGAGGATCCGTCTCCCCGG
TCCTTGCACGCAAGATGATCACCGAGAAATACGGCATTGACCCCAACGACGTCGTCAAGGAAGAGATCGACAAGGGACAG
TTCATCGTTATGACCAAAGACGGTCAGCACAAAGGCATCAAGATCGACGACCTCGAAGAGGAAGGTCTTGGCCGGAGAAA
GAACTGCCAGCGCTGCGAAACCAAGATCCCACGCCAGACCGATATCGTCTGCGGTAACTGGGGTGTCGTCGGCGAGAAAG
CCGGTAAGGCAACCTTCGTTGAGATCTGCTCCGACAAAGGTGCAATGGTCTTCGACGGCGCTGTGAAAGCAGGCGTCCTC
GCAACCTCAGCACCCGACGAGAAAGGCCTCGAGATCCGTGACAAGATCGAAAACGTCATGGTCAAGATGGGTAAGAAGAA
CCAGGCAAAACAGTTTGCAGAGATCGGCGAAGGTACCGACCGCCTGAAATACATCATGGCAGAGACCGGGCGCTGCATTA
AATGCTACGGTTGTATCGAAAACTGCCCGATCTGTTACTGTGTTGAGTGCTCCACCAAGAAGCCACACCTCGTCAGACCA
GGTCAGGTTCCGCCGGACTTCATGTTCCAGATGATAAGATTCGCCCACATCGCAGACTCCTGTGTGAACTGCGGTCAGTG
TACCGACGTCTGCCCACAGAACATCCCGAACTCACTCTTCATGCACGCCCAGCAGGTCGAGCTTGAAAAGATGTTCGGTC
ACAAGCCGGGTATGGACATGGAACTCCCAGTCCTCGCATTCGCCGAAGAAATCGACGAGCGCGCCCGTCTGCATGCAACC
GGCTCCGACATGATCTACGAGAACGTGTTCGGCGAAGAGAAATAA

Upstream 100 bases:

>100_bases
CAGCAAACATGCTGACCAACAATGCACTCGACCCGGTTTGTAAGATTCCGGAGTTCAAGGCATGTGCTGTGAAAGTTGAA
AAGATTGCGGAGGCCTAAAA

Downstream 100 bases:

>100_bases
TCTTCACCCAGCTACAGGAAAACCAATTACAGAGTTGGCCGGGAAGTGAGCTTTCACTTCCAAGGCATCTCTCTGATCTA
TTTTTAAAAGATGTAGGTAG

Product: formate dehydrogenase, beta subunit (F420)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 413

Protein sequence:

>414_residues
MSAKGDMFYAWTNVSDIKGECGGAVTSILKYLLESKTVDAVLTVQKGADVFDAEPVVITDPADLVKSAGSLHCGTLLLPK
LIKKYLNGAKDMKLAVTCKGCDAKAMYELAKRQQINLDNIVMIGLNCGGSVSPVLARKMITEKYGIDPNDVVKEEIDKGQ
FIVMTKDGQHKGIKIDDLEEEGLGRRKNCQRCETKIPRQTDIVCGNWGVVGEKAGKATFVEICSDKGAMVFDGAVKAGVL
ATSAPDEKGLEIRDKIENVMVKMGKKNQAKQFAEIGEGTDRLKYIMAETGRCIKCYGCIENCPICYCVECSTKKPHLVRP
GQVPPDFMFQMIRFAHIADSCVNCGQCTDVCPQNIPNSLFMHAQQVELEKMFGHKPGMDMELPVLAFAEEIDERARLHAT
GSDMIYENVFGEEK

Sequences:

>Translated_414_residues
MSAKGDMFYAWTNVSDIKGECGGAVTSILKYLLESKTVDAVLTVQKGADVFDAEPVVITDPADLVKSAGSLHCGTLLLPK
LIKKYLNGAKDMKLAVTCKGCDAKAMYELAKRQQINLDNIVMIGLNCGGSVSPVLARKMITEKYGIDPNDVVKEEIDKGQ
FIVMTKDGQHKGIKIDDLEEEGLGRRKNCQRCETKIPRQTDIVCGNWGVVGEKAGKATFVEICSDKGAMVFDGAVKAGVL
ATSAPDEKGLEIRDKIENVMVKMGKKNQAKQFAEIGEGTDRLKYIMAETGRCIKCYGCIENCPICYCVECSTKKPHLVRP
GQVPPDFMFQMIRFAHIADSCVNCGQCTDVCPQNIPNSLFMHAQQVELEKMFGHKPGMDMELPVLAFAEEIDERARLHAT
GSDMIYENVFGEEK
>Mature_413_residues
SAKGDMFYAWTNVSDIKGECGGAVTSILKYLLESKTVDAVLTVQKGADVFDAEPVVITDPADLVKSAGSLHCGTLLLPKL
IKKYLNGAKDMKLAVTCKGCDAKAMYELAKRQQINLDNIVMIGLNCGGSVSPVLARKMITEKYGIDPNDVVKEEIDKGQF
IVMTKDGQHKGIKIDDLEEEGLGRRKNCQRCETKIPRQTDIVCGNWGVVGEKAGKATFVEICSDKGAMVFDGAVKAGVLA
TSAPDEKGLEIRDKIENVMVKMGKKNQAKQFAEIGEGTDRLKYIMAETGRCIKCYGCIENCPICYCVECSTKKPHLVRPG
QVPPDFMFQMIRFAHIADSCVNCGQCTDVCPQNIPNSLFMHAQQVELEKMFGHKPGMDMELPVLAFAEEIDERARLHATG
SDMIYENVFGEEK

Specific function: Catalyzes the oxidation of formate [H]

COG id: COG1035

COG function: function code C; Coenzyme F420-reducing hydrogenase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR007516
- InterPro:   IPR007525
- InterPro:   IPR012285
- InterPro:   IPR009051 [H]

Pfam domain/function: PF04432 FrhB_FdhB_C; PF04422 FrhB_FdhB_N [H]

EC number: =1.2.1.2 [H]

Molecular weight: Translated: 45446; Mature: 45315

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.8 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
9.2 %Cys+Met (Translated Protein)
4.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
9.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAKGDMFYAWTNVSDIKGECGGAVTSILKYLLESKTVDAVLTVQKGADVFDAEPVVITD
CCCCCCEEEEECCCHHCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEEC
PADLVKSAGSLHCGTLLLPKLIKKYLNGAKDMKLAVTCKGCDAKAMYELAKRQQINLDNI
CHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCE
VMIGLNCGGSVSPVLARKMITEKYGIDPNDVVKEEIDKGQFIVMTKDGQHKGIKIDDLEE
EEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCH
EGLGRRKNCQRCETKIPRQTDIVCGNWGVVGEKAGKATFVEICSDKGAMVFDGAVKAGVL
HCCCCCCCHHHHHHCCCCCCCEEECCCCCCCCCCCCEEEEEECCCCCCEEECCCHHHCEE
ATSAPDEKGLEIRDKIENVMVKMGKKNQAKQFAEIGEGTDRLKYIMAETGRCIKCYGCIE
ECCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEEHHC
NCPICYCVECSTKKPHLVRPGQVPPDFMFQMIRFAHIADSCVNCGQCTDVCPQNIPNSLF
CCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCHHHH
MHAQQVELEKMFGHKPGMDMELPVLAFAEEIDERARLHATGSDMIYENVFGEEK
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHEECCCCHHHHHHHCCCCC
>Mature Secondary Structure 
SAKGDMFYAWTNVSDIKGECGGAVTSILKYLLESKTVDAVLTVQKGADVFDAEPVVITD
CCCCCEEEEECCCHHCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEEC
PADLVKSAGSLHCGTLLLPKLIKKYLNGAKDMKLAVTCKGCDAKAMYELAKRQQINLDNI
CHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCE
VMIGLNCGGSVSPVLARKMITEKYGIDPNDVVKEEIDKGQFIVMTKDGQHKGIKIDDLEE
EEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCH
EGLGRRKNCQRCETKIPRQTDIVCGNWGVVGEKAGKATFVEICSDKGAMVFDGAVKAGVL
HCCCCCCCHHHHHHCCCCCCCEEECCCCCCCCCCCCEEEEEECCCCCCEEECCCHHHCEE
ATSAPDEKGLEIRDKIENVMVKMGKKNQAKQFAEIGEGTDRLKYIMAETGRCIKCYGCIE
ECCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEEHHC
NCPICYCVECSTKKPHLVRPGQVPPDFMFQMIRFAHIADSCVNCGQCTDVCPQNIPNSLF
CCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCHHHH
MHAQQVELEKMFGHKPGMDMELPVLAFAEEIDERARLHATGSDMIYENVFGEEK
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHEECCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9006048 [H]