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The map label for this gene is eIF5A [H]

Identifier: 124485253

GI number: 124485253

Start: 411339

End: 411794

Strand: Reverse

Name: eIF5A [H]

Synonym: Mlab_0426

Alternate gene names: 124485253

Gene position: 411794-411339 (Counterclockwise)

Preceding gene: 124485259

Following gene: 124485252

Centisome position: 22.81

GC content: 46.27

Gene sequence:

>456_bases
ATGAATTCTTGCCTATGGATGAGTGCCGTAACACTCATAAGCAATCACCTCCCATACTTAGAGAGATATACTATGAAGGA
ACAGACTGAAGTTGGAAAACTGAAAGAAGGTCGTTACGTTGTCGTTGACGATGAGCCATGCAAGATCCAGAGCATCTCCA
TCTCCAAACCGGGAAAACACGGAGCAGCAAAGGCAAGATTAGATGTTGTCGGTCTCTTTGATGGACAGAAACGCTCGGTT
GTCTCCCCGACCTCGGCAACCGTCTATGCACCGATAGTTGAGAGAAAGACCGGACAGATCTTAACGATTGCAGGAAACGT
TGTCACGTTCATGGATATGAAAGACTTCAATAACTTTGAACTTATTGTAGAGGATGAACACATTCTGGCAACCTTCCAGC
CGGCTCAGGAAGTTCCCTACATCGAGTCACTCGGCAAGCGTAAGCTTGACCTCTAA

Upstream 100 bases:

>100_bases
GAGGAGCAAGCGCTTCCTCGACCATGGGAGCAACTTTGTCGCAAACAAAAAGAAACTCTGTCGGATCCATACTTATTAGT
TGTATTGGTGGGATATCCAC

Downstream 100 bases:

>100_bases
GACTGCACAATAATCCTATATGCAGTCTTTCTCTAACACTCTTTTTGCTGATGCTGAAAGCGAATATTCAGATGCATCAT
ATGGGATATTTGGCGTTCCC

Product: translation initiation factor 5A (eIF-5A)

Products: NA

Alternate protein names: Hypusine-containing protein; eIF-5A [H]

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MNSCLWMSAVTLISNHLPYLERYTMKEQTEVGKLKEGRYVVVDDEPCKIQSISISKPGKHGAAKARLDVVGLFDGQKRSV
VSPTSATVYAPIVERKTGQILTIAGNVVTFMDMKDFNNFELIVEDEHILATFQPAQEVPYIESLGKRKLDL

Sequences:

>Translated_151_residues
MNSCLWMSAVTLISNHLPYLERYTMKEQTEVGKLKEGRYVVVDDEPCKIQSISISKPGKHGAAKARLDVVGLFDGQKRSV
VSPTSATVYAPIVERKTGQILTIAGNVVTFMDMKDFNNFELIVEDEHILATFQPAQEVPYIESLGKRKLDL
>Mature_151_residues
MNSCLWMSAVTLISNHLPYLERYTMKEQTEVGKLKEGRYVVVDDEPCKIQSISISKPGKHGAAKARLDVVGLFDGQKRSV
VSPTSATVYAPIVERKTGQILTIAGNVVTFMDMKDFNNFELIVEDEHILATFQPAQEVPYIESLGKRKLDL

Specific function: Functions by promoting the formation of the first peptide bond [H]

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eIF-5A family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320801, Length=80, Percent_Identity=37.5, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR019769
- InterPro:   IPR001884
- InterPro:   IPR022847
- InterPro:   IPR020189
- InterPro:   IPR014722
- InterPro:   IPR008991 [H]

Pfam domain/function: PF01287 eIF-5a [H]

EC number: NA

Molecular weight: Translated: 16889; Mature: 16889

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS00302 IF5A_HYPUSINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSCLWMSAVTLISNHLPYLERYTMKEQTEVGKLKEGRYVVVDDEPCKIQSISISKPGKH
CCCCHHHHHHHHHHCCCCHHHHHCCHHHHHCCCCCCCCEEEECCCCCEEEEEECCCCCCC
GAAKARLDVVGLFDGQKRSVVSPTSATVYAPIVERKTGQILTIAGNVVTFMDMKDFNNFE
CCCEEEEEEEEECCCCCCCEECCCCCEEEEEEECCCCCCEEEEECCEEEEEECCCCCCEE
LIVEDEHILATFQPAQEVPYIESLGKRKLDL
EEEECCEEEEEECCCCCCCHHHHCCCCCCCC
>Mature Secondary Structure
MNSCLWMSAVTLISNHLPYLERYTMKEQTEVGKLKEGRYVVVDDEPCKIQSISISKPGKH
CCCCHHHHHHHHHHCCCCHHHHHCCHHHHHCCCCCCCCEEEECCCCCEEEEEECCCCCCC
GAAKARLDVVGLFDGQKRSVVSPTSATVYAPIVERKTGQILTIAGNVVTFMDMKDFNNFE
CCCEEEEEEEEECCCCCCCEECCCCCEEEEEEECCCCCCEEEEECCEEEEEECCCCCCEE
LIVEDEHILATFQPAQEVPYIESLGKRKLDL
EEEECCEEEEEECCCCCCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA