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The map label for this gene is ileS

Identifier: 124485013

GI number: 124485013

Start: 172604

End: 175804

Strand: Reverse

Name: ileS

Synonym: Mlab_0186

Alternate gene names: 124485013

Gene position: 175804-172604 (Counterclockwise)

Preceding gene: 124485020

Following gene: 124485012

Centisome position: 9.74

GC content: 53.86

Gene sequence:

>3201_bases
GTGAAAGAAATATCAGAAAGTTATGTACCCGCCGTTGTCGAAAACGAGGTTCGGGAGTACTGGAAAGCAAACAATACATA
TCGTGAAACACGCAAACTTCACGAATCAGGCAAACCGTGGCTCTTTGTCGATGGACCGCCGTACACCACAGGCTACATCC
ACCTTGGAACCGCCTGGAACAAGATCTTAAAAGACGCAATCCTCAGATACCACTCAATGACCGGCCAGCATATCATCGAA
CGTGCCGGTTACGATATGCACGGTCTCCCGATCGAGGTCAAAGTCGAGGAGAAGCTCGGATTCAAAAACAAGGCAGACAT
CGAGAAATACGGTGTGGCAAAGTTCATCGAAGAGTGCCGAGAGTTCGCTCTTACCCACAAAGATCTGATGAGCGAGCAGT
TCAAAGATCTCGGGACCTGGATGGACTTCGACGACCCCTATCAGACTGTCGATAAAGGATACATCGAAGCTGCCTGGTAT
ACCCTCAAACGCTGCGAAGAAGAGAAGATGCTCGAACGCGGATCCAGAGTCGTCAACTGGTGTCCCCGCTGCGGAACGGC
GATCGCCGATGCTGAGGTCGAATACTGGGACGAGACCGATCCGTCGATCTTCGTGAAATTCCCCATTCAGGGAACCGAGA
ACGAATACCTCGTCATCTGGACGACCACGCCCTGGACCCTCCCGGCAAACGTCGCCGTCGCCGTCGGTGAAGAGTTCGTC
TACGCAAAATGCCGTGCAGTAAAAGACGGGAAAAGCGAAGACCTCTGGATCGCAAAAGAGCTTGCCGAGCAGATCCTCAA
ATACGGAAAATATCAGGACTACTCGATCATCGAAACAAAGACCGGAGCCGAACTTGCCGGAACGAAATATATTTCCCCCC
TCGCATCCGCCGTTCCCATGCAGGCACAGATCGAACACCGTGTCGTCATCGCCGATTACGTAGCGATGGAAAACACCGGA
ATGGTCCATATCGCTCCGGGTCACGGCTGGGACGACTACCTCGTCGGTCTCAAAGAAAATCTTCCGGCCGTCTGTCCGGT
CGACGGAAACGGAAACTTCACCGATGAAGCCGGTATCTTTGCAGGAAAATACGTCAAGGCACCCGAAACCAATCAGGAGG
TCATCGACGTTTTAGGAGACGCCATGCTTGCAGTCCGCAAGATCACCCACCGGTACGGGCACTGCTGGAGATGCAAGACG
CCGATCATCTACCGGGCAACTTCCCAGTGGTTCCTAAAAGTAAAAGACATCAGAGAAAAGATGCTCGAGGAGATCGCCGA
CGAAGTGACATGGTATCCAGAGTGGGCAGGCTCCGCCAGATTCCACGACTGGGTCGAAGAGGCACGCGACTGGTGTATCT
CCCGGCAGAGATACTGGGGTATCCCGATCCCAGTCTGGGTCTGTCCGGTCTGTAACAAATATCATGTCGTCGGCAGATAC
GAAGAGCTCGAACAGCTCTCCGGCCAGAAGATGACTGACCCCCACCGGCCGTACGTCGATGACATCACGATCCCTTGTGA
ATGCGGCGGAACGATGAAGCGTATCCCGGACATCTTCGATGTCTGGTATGATTCGGGTATCGCCTCATGGGCGACCCTCC
GGTTCCCGGAAAAGCCCGAGGACTTCGGAAAATACTGGCCGGCGGACTTCATCCTCGAAGGACATGATCAGACCCGCGGC
TGGTTCTACTCGCAGCTCGCCTTATCCACGATCGCATTCGGCAAAGCCCCATACAAATCCGTTCTCATGCACGGATTCGC
TCTGGATGCTGAAGGAAAGAAGATGAGTAAAAGTCTTGGAAACGTCATCGCCCCGGAAGACGTTGCCAAACAGTTCGGTG
TTGACGTTATGCGCCAGTACATCCTTTCGGCGAATGCTCCGTGGGATGATATGCGTTTCTCCCTTGAAGGCGTCAAGACC
AACCACAGAATGTTCAATGTTCTCTGGAACGTCTACAAATTCCCGCTGCCGTACATGGCGCTCGACGGCTACAAACCGGC
AGCCAAAGACGGTGTCTGGGATCCGTCGGCAGTCGAAGATCATATCTCTGAATTCTGCAGAGAAGACCGCTGGCTCATCT
CCCGTGTGAACTCGCTTGCCGAGCAGGTTACCAAAGAGATGGAAGTCTGCAACCTTCACCGGGCGACCAGACCGATCAGC
ACGTTCATCCTCGACGAACTCTCCCGCTGGTATGTCCAGCTGGTCAGACCGAGAATGTGGCTCGAAGAAGAGTCCGTCTC
GAAGATGCAGGCCTACGATACTATGTATTACGTGATGCGCAGACTCGTAACCATATTCGCACCGTTTGCTCCCCACATCA
CTGAATGCATGTACCAGAACCTGAGATGCGAAGGCGATCTGCCCTCAGTCCATATGGTCGACTGGTTCAGCGGAAACGAT
GCACTCCGCGACCCCGTTCTCGAAGAGGAGATGGAGATCGTGCAGGAGTTCGACGAAGCGGTCGCAAACGCCCGTCAGAA
CGGAAAACGCAAAGGACGCTGGCCGGTTGGAACGGTCGTTGTCGCGACCGATTCGGAAAAGGTCGCCGGCGCCGTTTCAG
CGATGAACGATATGTGCTGTGACCGGGCAAATGCCCGGACCGTCACGGTCGTCAAAGGCGTCTGGGACAAACTCGACTGG
ACTGCCGTTCCGGTCATGAAAGTGATCGGCAAACAGTTCGGACGGGACGGACCCAAAGTCAAGGCATTCATCGAAGAAGC
AAACGGAACCAAGCTCAAAGCTCTGCTGACTGCAGACGGAAAAGTCAGCATGGAAAAGGACGGATTCACTGCAGAACTGA
CCGAAGAGCACATGACCTTCGAAGAAAAGATGCCGGAAAACATCTTCTCCTCCCCGATGGAGAACGGAACGATCTACGTC
GATGTGACTCTCACGCCGGAACTCGAAGCAGAAGGATACTCGCGTGAAGTCATCCGCAGAATCCAGGAGATGCGAAAACA
GGCCGGTCTCGCCGTCGATGCAAAGATCAAAGCCGAAGTCGTCATCGATGATGCACGGGTCATGCCCCTTGTGGACTCAA
AGCATGACGTTATCGAAACCGAGGTCAGAGCAAACTGTCTAAAAATCAGAGTGCCGGACGGAGAAACCTGTTCCTGCAGA
GTCGCCGATGAAGCGATCCTTGCAATGGACTGGGAGATCGACGATCTCAAGGTCAGAATCAGCATCTCGAAAGCAGAATA
A

Upstream 100 bases:

>100_bases
TCTCCCGGAAAAAATCCGGACGGAAATTCCGCTTGGATACAAAACCCCTTATGTATACCGACAACCAATAGTTACCCACA
TATTGAGTGAGGGAAAACTC

Downstream 100 bases:

>100_bases
TACCCTCCTCTTTTTTCAATATCGGCATTCTCCGTACTAAAACACTTATTCCATCACGACCAATTCAAAATAACAGAAGG
GATAAACTTGAGTACAGTAG

Product: isoleucyl-tRNA synthetase

Products: NA

Alternate protein names: Isoleucine--tRNA ligase; IleRS

Number of amino acids: Translated: 1066; Mature: 1066

Protein sequence:

>1066_residues
MKEISESYVPAVVENEVREYWKANNTYRETRKLHESGKPWLFVDGPPYTTGYIHLGTAWNKILKDAILRYHSMTGQHIIE
RAGYDMHGLPIEVKVEEKLGFKNKADIEKYGVAKFIEECREFALTHKDLMSEQFKDLGTWMDFDDPYQTVDKGYIEAAWY
TLKRCEEEKMLERGSRVVNWCPRCGTAIADAEVEYWDETDPSIFVKFPIQGTENEYLVIWTTTPWTLPANVAVAVGEEFV
YAKCRAVKDGKSEDLWIAKELAEQILKYGKYQDYSIIETKTGAELAGTKYISPLASAVPMQAQIEHRVVIADYVAMENTG
MVHIAPGHGWDDYLVGLKENLPAVCPVDGNGNFTDEAGIFAGKYVKAPETNQEVIDVLGDAMLAVRKITHRYGHCWRCKT
PIIYRATSQWFLKVKDIREKMLEEIADEVTWYPEWAGSARFHDWVEEARDWCISRQRYWGIPIPVWVCPVCNKYHVVGRY
EELEQLSGQKMTDPHRPYVDDITIPCECGGTMKRIPDIFDVWYDSGIASWATLRFPEKPEDFGKYWPADFILEGHDQTRG
WFYSQLALSTIAFGKAPYKSVLMHGFALDAEGKKMSKSLGNVIAPEDVAKQFGVDVMRQYILSANAPWDDMRFSLEGVKT
NHRMFNVLWNVYKFPLPYMALDGYKPAAKDGVWDPSAVEDHISEFCREDRWLISRVNSLAEQVTKEMEVCNLHRATRPIS
TFILDELSRWYVQLVRPRMWLEEESVSKMQAYDTMYYVMRRLVTIFAPFAPHITECMYQNLRCEGDLPSVHMVDWFSGND
ALRDPVLEEEMEIVQEFDEAVANARQNGKRKGRWPVGTVVVATDSEKVAGAVSAMNDMCCDRANARTVTVVKGVWDKLDW
TAVPVMKVIGKQFGRDGPKVKAFIEEANGTKLKALLTADGKVSMEKDGFTAELTEEHMTFEEKMPENIFSSPMENGTIYV
DVTLTPELEAEGYSREVIRRIQEMRKQAGLAVDAKIKAEVVIDDARVMPLVDSKHDVIETEVRANCLKIRVPDGETCSCR
VADEAILAMDWEIDDLKVRISISKAE

Sequences:

>Translated_1066_residues
MKEISESYVPAVVENEVREYWKANNTYRETRKLHESGKPWLFVDGPPYTTGYIHLGTAWNKILKDAILRYHSMTGQHIIE
RAGYDMHGLPIEVKVEEKLGFKNKADIEKYGVAKFIEECREFALTHKDLMSEQFKDLGTWMDFDDPYQTVDKGYIEAAWY
TLKRCEEEKMLERGSRVVNWCPRCGTAIADAEVEYWDETDPSIFVKFPIQGTENEYLVIWTTTPWTLPANVAVAVGEEFV
YAKCRAVKDGKSEDLWIAKELAEQILKYGKYQDYSIIETKTGAELAGTKYISPLASAVPMQAQIEHRVVIADYVAMENTG
MVHIAPGHGWDDYLVGLKENLPAVCPVDGNGNFTDEAGIFAGKYVKAPETNQEVIDVLGDAMLAVRKITHRYGHCWRCKT
PIIYRATSQWFLKVKDIREKMLEEIADEVTWYPEWAGSARFHDWVEEARDWCISRQRYWGIPIPVWVCPVCNKYHVVGRY
EELEQLSGQKMTDPHRPYVDDITIPCECGGTMKRIPDIFDVWYDSGIASWATLRFPEKPEDFGKYWPADFILEGHDQTRG
WFYSQLALSTIAFGKAPYKSVLMHGFALDAEGKKMSKSLGNVIAPEDVAKQFGVDVMRQYILSANAPWDDMRFSLEGVKT
NHRMFNVLWNVYKFPLPYMALDGYKPAAKDGVWDPSAVEDHISEFCREDRWLISRVNSLAEQVTKEMEVCNLHRATRPIS
TFILDELSRWYVQLVRPRMWLEEESVSKMQAYDTMYYVMRRLVTIFAPFAPHITECMYQNLRCEGDLPSVHMVDWFSGND
ALRDPVLEEEMEIVQEFDEAVANARQNGKRKGRWPVGTVVVATDSEKVAGAVSAMNDMCCDRANARTVTVVKGVWDKLDW
TAVPVMKVIGKQFGRDGPKVKAFIEEANGTKLKALLTADGKVSMEKDGFTAELTEEHMTFEEKMPENIFSSPMENGTIYV
DVTLTPELEAEGYSREVIRRIQEMRKQAGLAVDAKIKAEVVIDDARVMPLVDSKHDVIETEVRANCLKIRVPDGETCSCR
VADEAILAMDWEIDDLKVRISISKAE
>Mature_1066_residues
MKEISESYVPAVVENEVREYWKANNTYRETRKLHESGKPWLFVDGPPYTTGYIHLGTAWNKILKDAILRYHSMTGQHIIE
RAGYDMHGLPIEVKVEEKLGFKNKADIEKYGVAKFIEECREFALTHKDLMSEQFKDLGTWMDFDDPYQTVDKGYIEAAWY
TLKRCEEEKMLERGSRVVNWCPRCGTAIADAEVEYWDETDPSIFVKFPIQGTENEYLVIWTTTPWTLPANVAVAVGEEFV
YAKCRAVKDGKSEDLWIAKELAEQILKYGKYQDYSIIETKTGAELAGTKYISPLASAVPMQAQIEHRVVIADYVAMENTG
MVHIAPGHGWDDYLVGLKENLPAVCPVDGNGNFTDEAGIFAGKYVKAPETNQEVIDVLGDAMLAVRKITHRYGHCWRCKT
PIIYRATSQWFLKVKDIREKMLEEIADEVTWYPEWAGSARFHDWVEEARDWCISRQRYWGIPIPVWVCPVCNKYHVVGRY
EELEQLSGQKMTDPHRPYVDDITIPCECGGTMKRIPDIFDVWYDSGIASWATLRFPEKPEDFGKYWPADFILEGHDQTRG
WFYSQLALSTIAFGKAPYKSVLMHGFALDAEGKKMSKSLGNVIAPEDVAKQFGVDVMRQYILSANAPWDDMRFSLEGVKT
NHRMFNVLWNVYKFPLPYMALDGYKPAAKDGVWDPSAVEDHISEFCREDRWLISRVNSLAEQVTKEMEVCNLHRATRPIS
TFILDELSRWYVQLVRPRMWLEEESVSKMQAYDTMYYVMRRLVTIFAPFAPHITECMYQNLRCEGDLPSVHMVDWFSGND
ALRDPVLEEEMEIVQEFDEAVANARQNGKRKGRWPVGTVVVATDSEKVAGAVSAMNDMCCDRANARTVTVVKGVWDKLDW
TAVPVMKVIGKQFGRDGPKVKAFIEEANGTKLKALLTADGKVSMEKDGFTAELTEEHMTFEEKMPENIFSSPMENGTIYV
DVTLTPELEAEGYSREVIRRIQEMRKQAGLAVDAKIKAEVVIDDARVMPLVDSKHDVIETEVRANCLKIRVPDGETCSCR
VADEAILAMDWEIDDLKVRISISKAE

Specific function: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activi

COG id: COG0060

COG function: function code J; Isoleucyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily

Homologues:

Organism=Homo sapiens, GI94721239, Length=1022, Percent_Identity=32.6810176125245, Blast_Score=531, Evalue=1e-150,
Organism=Homo sapiens, GI94721241, Length=1022, Percent_Identity=32.6810176125245, Blast_Score=531, Evalue=1e-150,
Organism=Homo sapiens, GI46852147, Length=831, Percent_Identity=31.1672683513839, Blast_Score=349, Evalue=1e-95,
Organism=Homo sapiens, GI5454158, Length=860, Percent_Identity=24.7674418604651, Blast_Score=214, Evalue=3e-55,
Organism=Homo sapiens, GI268370297, Length=845, Percent_Identity=23.0769230769231, Blast_Score=194, Evalue=5e-49,
Organism=Homo sapiens, GI268370293, Length=845, Percent_Identity=23.0769230769231, Blast_Score=194, Evalue=6e-49,
Organism=Homo sapiens, GI268370295, Length=803, Percent_Identity=23.2876712328767, Blast_Score=191, Evalue=4e-48,
Organism=Escherichia coli, GI2367096, Length=870, Percent_Identity=32.8735632183908, Blast_Score=422, Evalue=1e-119,
Organism=Escherichia coli, GI1790708, Length=856, Percent_Identity=23.481308411215, Blast_Score=216, Evalue=5e-57,
Organism=Caenorhabditis elegans, GI17541896, Length=1033, Percent_Identity=30.1064859632139, Blast_Score=479, Evalue=1e-135,
Organism=Caenorhabditis elegans, GI71980946, Length=802, Percent_Identity=26.9326683291771, Blast_Score=267, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI17510661, Length=830, Percent_Identity=24.4578313253012, Blast_Score=224, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI72001587, Length=846, Percent_Identity=23.758865248227, Blast_Score=204, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6319395, Length=1058, Percent_Identity=32.1361058601134, Blast_Score=513, Evalue=1e-146,
Organism=Saccharomyces cerevisiae, GI6325217, Length=901, Percent_Identity=28.8568257491676, Blast_Score=307, Evalue=7e-84,
Organism=Saccharomyces cerevisiae, GI6321531, Length=844, Percent_Identity=23.696682464455, Blast_Score=209, Evalue=3e-54,
Organism=Drosophila melanogaster, GI28574730, Length=1063, Percent_Identity=30.8560677328316, Blast_Score=507, Evalue=1e-143,
Organism=Drosophila melanogaster, GI24668547, Length=1063, Percent_Identity=30.8560677328316, Blast_Score=507, Evalue=1e-143,
Organism=Drosophila melanogaster, GI24668543, Length=1063, Percent_Identity=30.8560677328316, Blast_Score=507, Evalue=1e-143,
Organism=Drosophila melanogaster, GI281366294, Length=797, Percent_Identity=27.8544542032622, Blast_Score=300, Evalue=4e-81,
Organism=Drosophila melanogaster, GI17864482, Length=916, Percent_Identity=25, Blast_Score=236, Evalue=4e-62,
Organism=Drosophila melanogaster, GI24653289, Length=916, Percent_Identity=25, Blast_Score=236, Evalue=4e-62,
Organism=Drosophila melanogaster, GI21355675, Length=898, Percent_Identity=22.6057906458797, Blast_Score=199, Evalue=1e-50,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYI_METLZ (A2SPV6)

Other databases:

- EMBL:   CP000559
- RefSeq:   YP_001029629.1
- ProteinModelPortal:   A2SPV6
- STRING:   A2SPV6
- GeneID:   4795794
- GenomeReviews:   CP000559_GR
- KEGG:   mla:Mlab_0186
- eggNOG:   arNOG04395
- HOGENOM:   HBG577712
- OMA:   DCHGLPA
- PhylomeDB:   A2SPV6
- ProtClustDB:   PRK06039
- BioCyc:   MLAB410358:MLAB_0186-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_02003
- InterPro:   IPR001412
- InterPro:   IPR002300
- InterPro:   IPR002301
- InterPro:   IPR014729
- InterPro:   IPR009080
- InterPro:   IPR013155
- InterPro:   IPR009008
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11946:SF9
- PRINTS:   PR00984
- TIGRFAMs:   TIGR00392

Pfam domain/function: PF08264 Anticodon_1; PF00133 tRNA-synt_1; SSF47323 tRNAsyn_1a_bind; SSF50677 ValRS_IleRS_edit

EC number: =6.1.1.5

Molecular weight: Translated: 121911; Mature: 121911

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 597-597

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEISESYVPAVVENEVREYWKANNTYRETRKLHESGKPWLFVDGPPYTTGYIHLGTAWN
CCCCHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEECCCCCCEEEEEECHHHH
KILKDAILRYHSMTGQHIIERAGYDMHGLPIEVKVEEKLGFKNKADIEKYGVAKFIEECR
HHHHHHHHHHHHCHHHHHHHHCCCCCCCCCEEEEEHHHCCCCCCCCHHHHHHHHHHHHHH
EFALTHKDLMSEQFKDLGTWMDFDDPYQTVDKGYIEAAWYTLKRCEEEKMLERGSRVVNW
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHH
CPRCGTAIADAEVEYWDETDPSIFVKFPIQGTENEYLVIWTTTPWTLPANVAVAVGEEFV
CCCCCCCCCCCCEEECCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCCEEEECCCHHH
YAKCRAVKDGKSEDLWIAKELAEQILKYGKYQDYSIIETKTGAELAGTKYISPLASAVPM
HHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCC
QAQIEHRVVIADYVAMENTGMVHIAPGHGWDDYLVGLKENLPAVCPVDGNGNFTDEAGIF
HHHHCCEEEEEEEEEECCCCEEEEECCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCE
AGKYVKAPETNQEVIDVLGDAMLAVRKITHRYGHCWRCKTPIIYRATSQWFLKVKDIREK
ECCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEEECHHHHHHHHHHHHH
MLEEIADEVTWYPEWAGSARFHDWVEEARDWCISRQRYWGIPIPVWVCPVCNKYHVVGRY
HHHHHHHHCEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCEEECCCH
EELEQLSGQKMTDPHRPYVDDITIPCECGGTMKRIPDIFDVWYDSGIASWATLRFPEKPE
HHHHHHCCCCCCCCCCCCCCCEEEECCCCCCHHHCHHHHHHHHCCCCCCCEEEECCCCCH
DFGKYWPADFILEGHDQTRGWFYSQLALSTIAFGKAPYKSVLMHGFALDAEGKKMSKSLG
HHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCEEECCCCHHHHHHHC
NVIAPEDVAKQFGVDVMRQYILSANAPWDDMRFSLEGVKTNHRMFNVLWNVYKFPLPYMA
CCCCCHHHHHHHCHHHHHHHHHCCCCCHHHHEEEECCCCCHHHHHHHHHHHHHCCCCCEE
LDGYKPAAKDGVWDPSAVEDHISEFCREDRWLISRVNSLAEQVTKEMEVCNLHRATRPIS
ECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TFILDELSRWYVQLVRPRMWLEEESVSKMQAYDTMYYVMRRLVTIFAPFAPHITECMYQN
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHC
LRCEGDLPSVHMVDWFSGNDALRDPVLEEEMEIVQEFDEAVANARQNGKRKGRWPVGTVV
CCCCCCCCCEEEEEEECCCCHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
VATDSEKVAGAVSAMNDMCCDRANARTVTVVKGVWDKLDWTAVPVMKVIGKQFGRDGPKV
EEECCHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHCCCCHHHHHHHHHHHHHCCCCCCE
KAFIEEANGTKLKALLTADGKVSMEKDGFTAELTEEHMTFEEKMPENIFSSPMENGTIYV
EHHEECCCCCEEEEEEECCCCEEECCCCCCHHHHHHHHHHHHHCCHHHHCCCCCCCEEEE
DVTLTPELEAEGYSREVIRRIQEMRKQAGLAVDAKIKAEVVIDDARVMPLVDSKHDVIET
EEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEECEEEEEEEEECCEEEEEECCCCHHHHH
EVRANCLKIRVPDGETCSCRVADEAILAMDWEIDDLKVRISISKAE
HHCCCEEEEECCCCCCEEEEECCCEEEEEECCCCCEEEEEEEECCC
>Mature Secondary Structure
MKEISESYVPAVVENEVREYWKANNTYRETRKLHESGKPWLFVDGPPYTTGYIHLGTAWN
CCCCHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEECCCCCCEEEEEECHHHH
KILKDAILRYHSMTGQHIIERAGYDMHGLPIEVKVEEKLGFKNKADIEKYGVAKFIEECR
HHHHHHHHHHHHCHHHHHHHHCCCCCCCCCEEEEEHHHCCCCCCCCHHHHHHHHHHHHHH
EFALTHKDLMSEQFKDLGTWMDFDDPYQTVDKGYIEAAWYTLKRCEEEKMLERGSRVVNW
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHH
CPRCGTAIADAEVEYWDETDPSIFVKFPIQGTENEYLVIWTTTPWTLPANVAVAVGEEFV
CCCCCCCCCCCCEEECCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCCEEEECCCHHH
YAKCRAVKDGKSEDLWIAKELAEQILKYGKYQDYSIIETKTGAELAGTKYISPLASAVPM
HHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCC
QAQIEHRVVIADYVAMENTGMVHIAPGHGWDDYLVGLKENLPAVCPVDGNGNFTDEAGIF
HHHHCCEEEEEEEEEECCCCEEEEECCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCE
AGKYVKAPETNQEVIDVLGDAMLAVRKITHRYGHCWRCKTPIIYRATSQWFLKVKDIREK
ECCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEEECHHHHHHHHHHHHH
MLEEIADEVTWYPEWAGSARFHDWVEEARDWCISRQRYWGIPIPVWVCPVCNKYHVVGRY
HHHHHHHHCEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCEEECCCH
EELEQLSGQKMTDPHRPYVDDITIPCECGGTMKRIPDIFDVWYDSGIASWATLRFPEKPE
HHHHHHCCCCCCCCCCCCCCCEEEECCCCCCHHHCHHHHHHHHCCCCCCCEEEECCCCCH
DFGKYWPADFILEGHDQTRGWFYSQLALSTIAFGKAPYKSVLMHGFALDAEGKKMSKSLG
HHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCEEECCCCHHHHHHHC
NVIAPEDVAKQFGVDVMRQYILSANAPWDDMRFSLEGVKTNHRMFNVLWNVYKFPLPYMA
CCCCCHHHHHHHCHHHHHHHHHCCCCCHHHHEEEECCCCCHHHHHHHHHHHHHCCCCCEE
LDGYKPAAKDGVWDPSAVEDHISEFCREDRWLISRVNSLAEQVTKEMEVCNLHRATRPIS
ECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TFILDELSRWYVQLVRPRMWLEEESVSKMQAYDTMYYVMRRLVTIFAPFAPHITECMYQN
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHC
LRCEGDLPSVHMVDWFSGNDALRDPVLEEEMEIVQEFDEAVANARQNGKRKGRWPVGTVV
CCCCCCCCCEEEEEEECCCCHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
VATDSEKVAGAVSAMNDMCCDRANARTVTVVKGVWDKLDWTAVPVMKVIGKQFGRDGPKV
EEECCHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHCCCCHHHHHHHHHHHHHCCCCCCE
KAFIEEANGTKLKALLTADGKVSMEKDGFTAELTEEHMTFEEKMPENIFSSPMENGTIYV
EHHEECCCCCEEEEEEECCCCEEECCCCCCHHHHHHHHHHHHHCCHHHHCCCCCCCEEEE
DVTLTPELEAEGYSREVIRRIQEMRKQAGLAVDAKIKAEVVIDDARVMPLVDSKHDVIET
EEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEECEEEEEEEEECCEEEEEECCCCHHHHH
EVRANCLKIRVPDGETCSCRVADEAILAMDWEIDDLKVRISISKAE
HHCCCEEEEECCCCCCEEEEECCCEEEEEECCCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA