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The map label for this gene is trkG [C]

Identifier: 124484999

GI number: 124484999

Start: 158044

End: 159525

Strand: Reverse

Name: trkG [C]

Synonym: Mlab_0172

Alternate gene names: 124484999

Gene position: 159525-158044 (Counterclockwise)

Preceding gene: 124485000

Following gene: 124484998

Centisome position: 8.84

GC content: 51.96

Gene sequence:

>1482_bases
ATGGGGTATCTCAGGGAACTTCCGGCGATCGGTCGTGATATCGGGTCAGTGCTTCTGCTCATAGGCACCGCCACCCTTGT
TCCGATCATCGTCGGCTGTTTCTTTCAGGAATGGTATGCTCTGCCGTGGATGGCAAGTTCCACGTTTGCAATGCTCGGAC
TTGGCGGCCTCTTACATTTGCTGCCGAAAAATACGAAACCCCCAAGGGCCAGCCTCTCGATCTCGGCGACGGCAGTGATC
TGGGCATTGGTTGGGTTTCTCGGCTGTTTTCCCTTTATTTTTGCCGGTATGCCGCTGATCGACGCTGCATTCGAATCCAT
GTCGGCGTGGACGGGCACTGGATTTTCCATTGCAACGAACATCGAGAGCTGGCCAAAAACGATTCTTCTTTGGAGATCTC
TGATGCAGTGGATCGGCGGCCTTGGGATCGTGGCATTCACACTGACGGTGGCAAGCCGCTCAGGACTTGTCACCCAGAAT
CTCTACCGGTCCGAAGGAGGGTCGGAGTCGTTCATGCCAAGCGTTATCGCAACGGCTTTTCAGATGTGGAAGATCTATCT
GATTTTGACGCTGATCGCAATTATCGCAATCCTTTTGACGGGTCTTAGTCTCTGGGACGCCGTCAACGTCGCGTTCTGCG
CGATCGCGACCGGAGGAATGACGATTTACGCAGCGGGAATTACGCATTTCAACAATTTTGCGCTCGAGATGGTTTTGATT
CCGATCATGCTTGCCGGAGCGCTGCCGTTTCGGCTCTATTACGTGGTATATGTCAGCAGGTCGTTTCGGGAGATCCTGCA
CGACAGAATCCTGCATCTGATGGTCGGCGTGTACCTTTTCGTTGCCGCCGTTTTGATCGTCGAACTTTTCACTGCCGGGA
TGCCCCTTATGGAAACTCTGCGGGAAAGTCTCTTTATGGCCGGTTCGGTTGTGAGTTCCACCGGATTCCAGAACACGACC
TTTGCCGGATGGGGGCTCGCACCGATCATATTCCTTTCAATATTCCTTATGATCGAAGGAGCCCAGGGAAGTACATCTGG
AGGTATAAAACTGAATCGTCTGCAGGTTATGCTCGAAGCTTTGGGCTGGTGGTTTAGAAAAACCCTGCAGAGTCCAAAGG
CCGTGGTCCCGATGCGCCATGACGGCAAACCGATCTACGGAAAAGAAGGGGAAACGCTGATCGCAAAATCCCTGCTGATG
ATCCTGCTGTTTGTTCTGCTTATGCTTGGAACGCTGATCGTGTTCCTGCACGACCCATATTTCTCGGAGAATCTTGCACA
TACGATCTATGATCTCTGCAGCTGCATTGGAAACAACGGGAGCTCGACAGGAGTCGTTGGCCCGATGATGCCTGATTATG
CAAAGGTCGTGATGTTCTTTATTATGTGGATCGCGAGACTGGAAATTATTCCGGTGCTTATTCTGATCTGGGGTATCCTT
CGGGGATTCGATACGCAGAAGAAATCGGATAGAAGAGACTGA

Upstream 100 bases:

>100_bases
CTCTGGGTCAAAAAAGTATAACCGGTCTTACCATTCATTTTTTCCTGAAGACTGAATTCAGGCAACTACTATTATTATCA
AACACCTAATTGTACTACAA

Downstream 100 bases:

>100_bases
AAATATTGACAGCAGGTCTGAAACTTCGAAAATATTTCACCATTTAGCTATTATCGTCACTGGAAGTACACGATTGTTCC
TGCAGACATACATGATCCTT

Product: DNA gyrase/topoisomerase IV, subunit A

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 493; Mature: 492

Protein sequence:

>493_residues
MGYLRELPAIGRDIGSVLLLIGTATLVPIIVGCFFQEWYALPWMASSTFAMLGLGGLLHLLPKNTKPPRASLSISATAVI
WALVGFLGCFPFIFAGMPLIDAAFESMSAWTGTGFSIATNIESWPKTILLWRSLMQWIGGLGIVAFTLTVASRSGLVTQN
LYRSEGGSESFMPSVIATAFQMWKIYLILTLIAIIAILLTGLSLWDAVNVAFCAIATGGMTIYAAGITHFNNFALEMVLI
PIMLAGALPFRLYYVVYVSRSFREILHDRILHLMVGVYLFVAAVLIVELFTAGMPLMETLRESLFMAGSVVSSTGFQNTT
FAGWGLAPIIFLSIFLMIEGAQGSTSGGIKLNRLQVMLEALGWWFRKTLQSPKAVVPMRHDGKPIYGKEGETLIAKSLLM
ILLFVLLMLGTLIVFLHDPYFSENLAHTIYDLCSCIGNNGSSTGVVGPMMPDYAKVVMFFIMWIARLEIIPVLILIWGIL
RGFDTQKKSDRRD

Sequences:

>Translated_493_residues
MGYLRELPAIGRDIGSVLLLIGTATLVPIIVGCFFQEWYALPWMASSTFAMLGLGGLLHLLPKNTKPPRASLSISATAVI
WALVGFLGCFPFIFAGMPLIDAAFESMSAWTGTGFSIATNIESWPKTILLWRSLMQWIGGLGIVAFTLTVASRSGLVTQN
LYRSEGGSESFMPSVIATAFQMWKIYLILTLIAIIAILLTGLSLWDAVNVAFCAIATGGMTIYAAGITHFNNFALEMVLI
PIMLAGALPFRLYYVVYVSRSFREILHDRILHLMVGVYLFVAAVLIVELFTAGMPLMETLRESLFMAGSVVSSTGFQNTT
FAGWGLAPIIFLSIFLMIEGAQGSTSGGIKLNRLQVMLEALGWWFRKTLQSPKAVVPMRHDGKPIYGKEGETLIAKSLLM
ILLFVLLMLGTLIVFLHDPYFSENLAHTIYDLCSCIGNNGSSTGVVGPMMPDYAKVVMFFIMWIARLEIIPVLILIWGIL
RGFDTQKKSDRRD
>Mature_492_residues
GYLRELPAIGRDIGSVLLLIGTATLVPIIVGCFFQEWYALPWMASSTFAMLGLGGLLHLLPKNTKPPRASLSISATAVIW
ALVGFLGCFPFIFAGMPLIDAAFESMSAWTGTGFSIATNIESWPKTILLWRSLMQWIGGLGIVAFTLTVASRSGLVTQNL
YRSEGGSESFMPSVIATAFQMWKIYLILTLIAIIAILLTGLSLWDAVNVAFCAIATGGMTIYAAGITHFNNFALEMVLIP
IMLAGALPFRLYYVVYVSRSFREILHDRILHLMVGVYLFVAAVLIVELFTAGMPLMETLRESLFMAGSVVSSTGFQNTTF
AGWGLAPIIFLSIFLMIEGAQGSTSGGIKLNRLQVMLEALGWWFRKTLQSPKAVVPMRHDGKPIYGKEGETLIAKSLLMI
LLFVLLMLGTLIVFLHDPYFSENLAHTIYDLCSCIGNNGSSTGVVGPMMPDYAKVVMFFIMWIARLEIIPVLILIWGILR
GFDTQKKSDRRD

Specific function: Low-Affinity Potassium Transport System. Interacts With Trk System Potassium Uptake Protein Trka. Trke Increases The Affinity Of The System. [C]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI1787626, Length=475, Percent_Identity=25.4736842105263, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI48994987, Length=480, Percent_Identity=25.2083333333333, Blast_Score=118, Evalue=7e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 54165; Mature: 54034

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYLRELPAIGRDIGSVLLLIGTATLVPIIVGCFFQEWYALPWMASSTFAMLGLGGLLHL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
LPKNTKPPRASLSISATAVIWALVGFLGCFPFIFAGMPLIDAAFESMSAWTGTGFSIATN
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEECC
IESWPKTILLWRSLMQWIGGLGIVAFTLTVASRSGLVTQNLYRSEGGSESFMPSVIATAF
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHH
QMWKIYLILTLIAIIAILLTGLSLWDAVNVAFCAIATGGMTIYAAGITHFNNFALEMVLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHH
PIMLAGALPFRLYYVVYVSRSFREILHDRILHLMVGVYLFVAAVLIVELFTAGMPLMETL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RESLFMAGSVVSSTGFQNTTFAGWGLAPIIFLSIFLMIEGAQGSTSGGIKLNRLQVMLEA
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHH
LGWWFRKTLQSPKAVVPMRHDGKPIYGKEGETLIAKSLLMILLFVLLMLGTLIVFLHDPY
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
FSENLAHTIYDLCSCIGNNGSSTGVVGPMMPDYAKVVMFFIMWIARLEIIPVLILIWGIL
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGFDTQKKSDRRD
HCCCCCCCCCCCC
>Mature Secondary Structure 
GYLRELPAIGRDIGSVLLLIGTATLVPIIVGCFFQEWYALPWMASSTFAMLGLGGLLHL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
LPKNTKPPRASLSISATAVIWALVGFLGCFPFIFAGMPLIDAAFESMSAWTGTGFSIATN
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEECC
IESWPKTILLWRSLMQWIGGLGIVAFTLTVASRSGLVTQNLYRSEGGSESFMPSVIATAF
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHH
QMWKIYLILTLIAIIAILLTGLSLWDAVNVAFCAIATGGMTIYAAGITHFNNFALEMVLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHH
PIMLAGALPFRLYYVVYVSRSFREILHDRILHLMVGVYLFVAAVLIVELFTAGMPLMETL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RESLFMAGSVVSSTGFQNTTFAGWGLAPIIFLSIFLMIEGAQGSTSGGIKLNRLQVMLEA
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHH
LGWWFRKTLQSPKAVVPMRHDGKPIYGKEGETLIAKSLLMILLFVLLMLGTLIVFLHDPY
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
FSENLAHTIYDLCSCIGNNGSSTGVVGPMMPDYAKVVMFFIMWIARLEIIPVLILIWGIL
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGFDTQKKSDRRD
HCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]