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The map label for this gene is argK [C]

Identifier: 124266208

GI number: 124266208

Start: 1079893

End: 1080906

Strand: Direct

Name: argK [C]

Synonym: Mpe_A1015

Alternate gene names: 124266208

Gene position: 1079893-1080906 (Clockwise)

Preceding gene: 124266207

Following gene: 124266209

Centisome position: 26.7

GC content: 72.19

Gene sequence:

>1014_bases
ATGGCTGCCGCCTCCGACCAGACGCTGATCGACGGCGTGCTCGGCCCGGCCGGGCCGGTGCAGCGCCGCGCCATCGCCAA
GACCATCACGCTGCTCGAGTCCACGCGCGAGGAGCATCGCGCACGCGCCGACGAGCTGATCAACACCCTGCTGCCGCACA
GCGGACGCTCGCTGCGGCTGGGCATCTCGGGCGTGCCGGGGGTCGGCAAGTCCACCTTTATCGAGAGCCTGGGGCTGTTC
CTGGTGGAGCGCGGGCACCGCGTCGCGGTGCTGGCTGTGGACCCGTCGTCCAGCGTCTCGGGCGGCTCCATCCTGGGCGA
CAAGACGCGCATGGAGCGGCTGTCGGTCGACGAGCGCGCCTACATCCGCCCCAGCCCGGCCTCGGGCACGCTGGGTGGCG
TGGCCGAGAAGACGCGCGAGTCGATGCTGGTGGCCGAGGCGGCGGGCTACGACGTGGTGATCGTCGAGACCGTCGGCGTC
GGCCAGAGCGAGATCGCGGTGGCCGGCATGACCGACATGTTCGTGCTGCTGCAGTTGCCCAACGCCGGCGACGACCTGCA
GGCCATCAAGAAGGGCGTGATGGAGCTGGCCGATCTGGTGGTGATCAACAAGGCCGACCTCGACGAGGCCGCCGCCACGC
GGGCGCGTGCGCAGATCACCTCGGCGCTGCGGCTGCTGGGGCAGCACGGCAACCCGATGACGGCCCACCACGATGCCCAG
CTGTGGCATCCGCAGGTGCTGCAGCTCAGCGCGCTGAAGGGCGTGGGTCTGGCGGAGTTCTGGGTCGCCGTGGAGCGCTT
TCGCGAACTGCAGACGCAGAGCGGCCGGCTCGCGTCGCGCCGCCACCAGCAGGACCAGGCCTGGATGTGGGAGCGCATCG
AGGCCGGCCTGAAGGCGCGCTTTCGCGGCCACCCCGCCGTGCGCGAGGCGCTCTCCGCCACCAGCGCCGACGTGCGCGCC
GGTCGGCTGGCGGCCTCGGTCGCGGCACGCCGCCTGCTCGACCTCGCCGACTGA

Upstream 100 bases:

>100_bases
GCCGGCGTCAAGGGCATCTACGGTCCCGGTACGCCGATCCCGGCCTCGGCGAAGGACGTGCTCGAGCAGATCAAGAAGGC
CATCGCCGCGCCCTGATCCG

Downstream 100 bases:

>100_bases
TTCACGCACCGACTTCTGCCCCGTTCCGTCCCACCCGACACATCCATCCAGGCCGAGAGGACCATCCCCATGCACGACAT
CATCGAAGAGCTCAAGCGGC

Product: arginine/ornithine transport system ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MAAASDQTLIDGVLGPAGPVQRRAIAKTITLLESTREEHRARADELINTLLPHSGRSLRLGISGVPGVGKSTFIESLGLF
LVERGHRVAVLAVDPSSSVSGGSILGDKTRMERLSVDERAYIRPSPASGTLGGVAEKTRESMLVAEAAGYDVVIVETVGV
GQSEIAVAGMTDMFVLLQLPNAGDDLQAIKKGVMELADLVVINKADLDEAAATRARAQITSALRLLGQHGNPMTAHHDAQ
LWHPQVLQLSALKGVGLAEFWVAVERFRELQTQSGRLASRRHQQDQAWMWERIEAGLKARFRGHPAVREALSATSADVRA
GRLAASVAARRLLDLAD

Sequences:

>Translated_337_residues
MAAASDQTLIDGVLGPAGPVQRRAIAKTITLLESTREEHRARADELINTLLPHSGRSLRLGISGVPGVGKSTFIESLGLF
LVERGHRVAVLAVDPSSSVSGGSILGDKTRMERLSVDERAYIRPSPASGTLGGVAEKTRESMLVAEAAGYDVVIVETVGV
GQSEIAVAGMTDMFVLLQLPNAGDDLQAIKKGVMELADLVVINKADLDEAAATRARAQITSALRLLGQHGNPMTAHHDAQ
LWHPQVLQLSALKGVGLAEFWVAVERFRELQTQSGRLASRRHQQDQAWMWERIEAGLKARFRGHPAVREALSATSADVRA
GRLAASVAARRLLDLAD
>Mature_336_residues
AAASDQTLIDGVLGPAGPVQRRAIAKTITLLESTREEHRARADELINTLLPHSGRSLRLGISGVPGVGKSTFIESLGLFL
VERGHRVAVLAVDPSSSVSGGSILGDKTRMERLSVDERAYIRPSPASGTLGGVAEKTRESMLVAEAAGYDVVIVETVGVG
QSEIAVAGMTDMFVLLQLPNAGDDLQAIKKGVMELADLVVINKADLDEAAATRARAQITSALRLLGQHGNPMTAHHDAQL
WHPQVLQLSALKGVGLAEFWVAVERFRELQTQSGRLASRRHQQDQAWMWERIEAGLKARFRGHPAVREALSATSADVRAG
RLAASVAARRLLDLAD

Specific function: Probable GTPase. May also bind and hydrolyze ATP. May function as chaperone (Probable) [H]

COG id: COG1703

COG function: function code E; Putative periplasmic protein kinase ArgK and related GTPases of G3E family

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgK family [H]

Homologues:

Organism=Homo sapiens, GI26892295, Length=324, Percent_Identity=47.5308641975309, Blast_Score=288, Evalue=5e-78,
Organism=Escherichia coli, GI1789285, Length=275, Percent_Identity=50.1818181818182, Blast_Score=264, Evalue=7e-72,
Organism=Caenorhabditis elegans, GI71994271, Length=324, Percent_Identity=40.1234567901235, Blast_Score=239, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI71994275, Length=278, Percent_Identity=41.726618705036, Blast_Score=228, Evalue=2e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005129 [H]

Pfam domain/function: PF03308 ArgK [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 36071; Mature: 35940

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAASDQTLIDGVLGPAGPVQRRAIAKTITLLESTREEHRARADELINTLLPHSGRSLRL
CCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
GISGVPGVGKSTFIESLGLFLVERGHRVAVLAVDPSSSVSGGSILGDKTRMERLSVDERA
ECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHCCCCCC
YIRPSPASGTLGGVAEKTRESMLVAEAAGYDVVIVETVGVGQSEIAVAGMTDMFVLLQLP
EECCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHEEEECHHHEEEEEECC
NAGDDLQAIKKGVMELADLVVINKADLDEAAATRARAQITSALRLLGQHGNPMTAHHDAQ
CCCHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
LWHPQVLQLSALKGVGLAEFWVAVERFRELQTQSGRLASRRHQQDQAWMWERIEAGLKAR
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
FRGHPAVREALSATSADVRAGRLAASVAARRLLDLAD
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AAASDQTLIDGVLGPAGPVQRRAIAKTITLLESTREEHRARADELINTLLPHSGRSLRL
CCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
GISGVPGVGKSTFIESLGLFLVERGHRVAVLAVDPSSSVSGGSILGDKTRMERLSVDERA
ECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHCCCCCC
YIRPSPASGTLGGVAEKTRESMLVAEAAGYDVVIVETVGVGQSEIAVAGMTDMFVLLQLP
EECCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHEEEECHHHEEEEEECC
NAGDDLQAIKKGVMELADLVVINKADLDEAAATRARAQITSALRLLGQHGNPMTAHHDAQ
CCCHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
LWHPQVLQLSALKGVGLAEFWVAVERFRELQTQSGRLASRRHQQDQAWMWERIEAGLKAR
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
FRGHPAVREALSATSADVRAGRLAASVAARRLLDLAD
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Arg [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]