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The map label for this gene is xylR [H]

Identifier: 124266195

GI number: 124266195

Start: 1064436

End: 1066148

Strand: Reverse

Name: xylR [H]

Synonym: Mpe_A1002

Alternate gene names: 124266195

Gene position: 1066148-1064436 (Counterclockwise)

Preceding gene: 124266198

Following gene: 124266193

Centisome position: 26.36

GC content: 70.17

Gene sequence:

>1713_bases
ATGCCCCCCACCACCCACGCGGCGCCATCGGCGACGGTCCGCGCCGACGGACCGGACGACCGCACGCTCACCGAGCACCT
GCGTTTCTCGCCCGACGCCGGCCACATCGTGCTGTTCGAGCAGCGCATGCTGCTGATGCACGCGTCGTCGTTCGCCGAGC
TGCGGCGCGAGCTCATCGAACAGCTGGGCACCGGCAAGGCGCGCGAGCTGTTCACGCGGCTCGGCTACCAGCAGGGCTTC
GAGGACGGCCAGCGCCTGCGCGCCCTGTGCGGCACGGACCGTGACCGCATGCTCGAGCTCGGCCCGCGCCTGCGCGAGAT
CGAAGGCTTCGTGCGCAACCAGCCGATCGACGCTATGCAGTTCGACCTCGAAGGCGGCGAGTTCTGGGGCGACTACTACT
GGACCTCCTCCTGGGAGGCCGAAGCCCACCTCAAGCACTGCGGCGTGTTCGGCGAACCGGCCTGCTGGATGATGGTGGGC
TATGCGAGCGGCTGCTGCACCGCCATCCTCGGGCAACCGGTGCTGTGGCGCGAGATCGAGTGCGTGGCGATGGGCCACGA
GCGCTGCCGCGTGGTCGGTCGCCCGCTCGCCGCCTGGGACGACCTGAGCGAGCACGAGACCAACTTCCTGAAGATCGAGT
CCTTCGTGCGCACGCCACCGAAGGCCCGGCCGACCCGCAGTGCGCCGGCCAAGGTCTGCGTCCCGGGCGAGTTCGACGAC
TTCGTCGGCACCTCGGCCGGCTTCAACGCGGTGGCCAACCTGGTCCGCCGTGTCGGTGTGACCGACTCCACCGTGCTGTT
CCGCGGCGAGAGCGGCGTCGGCAAGGAGCGTTTCGCACGGGCGCTGCATTCGGTCAGCCGCCGGCACGAGCAGCCGATGG
TGTCGATCAACTGCGCGGCGATTCCGCCCGATCTGGTGGAATCCGAGCTGTTCGGTGTCGAGAAAGGTGCCTTCACCGGA
GCCGACCATTCGCGGCCCGGACGCTTCGAGCGGGCCCACGGCGGCACGCTGTTCCTCGACGAGATCAGCAGCCTGCCGCT
GCCGGCGCAGGGCAAGCTGCTGCGCGTGCTGCAGGAGCGCGAGATCGAGCGCGTGGGCGACGTGCGCGTGCGCAAGGTCG
ACGTGCGACTGGTCGCGGCGTCCAACCGCGACCTGCGCGACGAGGTCGAGGCCGGCCGATTCCGCGAGGACCTGTTCTAC
CGGCTCAACGTGTTCCCGATCGTCATTCCGCCGCTGCGCGAGCGCCTGGAGGACATCCCGCTGCTCGTCGCACTGTTCCT
GGAACGTTGCAACCGGCGCTGCGGCAAGCGCGTCGCCGGCCTGACCACGCGCGCCTACGACGCGCTGTGGGACTACCACT
GGCCCGGCAACGTGCGCGAGCTCGAGAACATGGTCGAGCGCGCGGTGATCCTGGCCGACGACGACGGCAAGATCGACGTG
CAGCACCTGTTCTCCGGCGGCGAGCAGCTCAAGCTGCGTTCGCTGAGCGTGGGCGCGCACGGCGAGCTGGTCCCGCGCGC
CGGCGAGGCCAGCGACCAGTGCAAGCGACTGGCCGACGACCTGCTGGCCCGCCTGCCGTCCTTCGAGCAGATCGAGTCGC
TGCTGTTCGAGCGCGCGATGGAGCGCAGCGACGGCAACATCTCCGCGGCCGCGCGCCTGCTGCGCCTGCGGCGCGGCCAG
GTCGAATACCGCCTCAAGAAGCGCGAGTCCTGA

Upstream 100 bases:

>100_bases
TTCCGGACCGGGGTCGCAGATTCATCATTTGCGACAACGAGAAAATGCGGATTGCCGCTTTTGACGAACAGGCCGGCCCC
GACCGGACCGAGGAGACAGC

Downstream 100 bases:

>100_bases
GGCGCGCGGCGACGCCCGCCCTCAGGCGCCGCGCCTGTCGTCCTGGATCAGCTGCCGCAGGCGCCGCCGCACCTTGACCG
GTGCCACGTCGTTGGTCATC

Product: phenol-degradation regulator

Products: NA

Alternate protein names: 67 kDa protein [H]

Number of amino acids: Translated: 570; Mature: 569

Protein sequence:

>570_residues
MPPTTHAAPSATVRADGPDDRTLTEHLRFSPDAGHIVLFEQRMLLMHASSFAELRRELIEQLGTGKARELFTRLGYQQGF
EDGQRLRALCGTDRDRMLELGPRLREIEGFVRNQPIDAMQFDLEGGEFWGDYYWTSSWEAEAHLKHCGVFGEPACWMMVG
YASGCCTAILGQPVLWREIECVAMGHERCRVVGRPLAAWDDLSEHETNFLKIESFVRTPPKARPTRSAPAKVCVPGEFDD
FVGTSAGFNAVANLVRRVGVTDSTVLFRGESGVGKERFARALHSVSRRHEQPMVSINCAAIPPDLVESELFGVEKGAFTG
ADHSRPGRFERAHGGTLFLDEISSLPLPAQGKLLRVLQEREIERVGDVRVRKVDVRLVAASNRDLRDEVEAGRFREDLFY
RLNVFPIVIPPLRERLEDIPLLVALFLERCNRRCGKRVAGLTTRAYDALWDYHWPGNVRELENMVERAVILADDDGKIDV
QHLFSGGEQLKLRSLSVGAHGELVPRAGEASDQCKRLADDLLARLPSFEQIESLLFERAMERSDGNISAAARLLRLRRGQ
VEYRLKKRES

Sequences:

>Translated_570_residues
MPPTTHAAPSATVRADGPDDRTLTEHLRFSPDAGHIVLFEQRMLLMHASSFAELRRELIEQLGTGKARELFTRLGYQQGF
EDGQRLRALCGTDRDRMLELGPRLREIEGFVRNQPIDAMQFDLEGGEFWGDYYWTSSWEAEAHLKHCGVFGEPACWMMVG
YASGCCTAILGQPVLWREIECVAMGHERCRVVGRPLAAWDDLSEHETNFLKIESFVRTPPKARPTRSAPAKVCVPGEFDD
FVGTSAGFNAVANLVRRVGVTDSTVLFRGESGVGKERFARALHSVSRRHEQPMVSINCAAIPPDLVESELFGVEKGAFTG
ADHSRPGRFERAHGGTLFLDEISSLPLPAQGKLLRVLQEREIERVGDVRVRKVDVRLVAASNRDLRDEVEAGRFREDLFY
RLNVFPIVIPPLRERLEDIPLLVALFLERCNRRCGKRVAGLTTRAYDALWDYHWPGNVRELENMVERAVILADDDGKIDV
QHLFSGGEQLKLRSLSVGAHGELVPRAGEASDQCKRLADDLLARLPSFEQIESLLFERAMERSDGNISAAARLLRLRRGQ
VEYRLKKRES
>Mature_569_residues
PPTTHAAPSATVRADGPDDRTLTEHLRFSPDAGHIVLFEQRMLLMHASSFAELRRELIEQLGTGKARELFTRLGYQQGFE
DGQRLRALCGTDRDRMLELGPRLREIEGFVRNQPIDAMQFDLEGGEFWGDYYWTSSWEAEAHLKHCGVFGEPACWMMVGY
ASGCCTAILGQPVLWREIECVAMGHERCRVVGRPLAAWDDLSEHETNFLKIESFVRTPPKARPTRSAPAKVCVPGEFDDF
VGTSAGFNAVANLVRRVGVTDSTVLFRGESGVGKERFARALHSVSRRHEQPMVSINCAAIPPDLVESELFGVEKGAFTGA
DHSRPGRFERAHGGTLFLDEISSLPLPAQGKLLRVLQEREIERVGDVRVRKVDVRLVAASNRDLRDEVEAGRFREDLFYR
LNVFPIVIPPLRERLEDIPLLVALFLERCNRRCGKRVAGLTTRAYDALWDYHWPGNVRELENMVERAVILADDDGKIDVQ
HLFSGGEQLKLRSLSVGAHGELVPRAGEASDQCKRLADDLLARLPSFEQIESLLFERAMERSDGNISAAARLLRLRRGQV
EYRLKKRES

Specific function: Regulatory protein of the TOL plasmid xyl operons. In the presence of m-xylene or m-methylbenzyl alcohol xylR activates both the xylCMABN operon and the regulatory gene xylS; xylS itself activates the xylXYZLTEGFJQKIH operon. XylR interacts with sigma- 54

COG id: COG1221

COG function: function code KT; Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=327, Percent_Identity=44.954128440367, Blast_Score=258, Evalue=5e-70,
Organism=Escherichia coli, GI87082117, Length=233, Percent_Identity=56.2231759656652, Blast_Score=254, Evalue=7e-69,
Organism=Escherichia coli, GI1789087, Length=239, Percent_Identity=52.7196652719665, Blast_Score=251, Evalue=1e-67,
Organism=Escherichia coli, GI87082152, Length=248, Percent_Identity=51.2096774193548, Blast_Score=239, Evalue=4e-64,
Organism=Escherichia coli, GI1788550, Length=311, Percent_Identity=42.443729903537, Blast_Score=239, Evalue=4e-64,
Organism=Escherichia coli, GI1789233, Length=378, Percent_Identity=37.8306878306878, Blast_Score=221, Evalue=1e-58,
Organism=Escherichia coli, GI1790299, Length=345, Percent_Identity=40.5797101449275, Blast_Score=220, Evalue=1e-58,
Organism=Escherichia coli, GI1788905, Length=216, Percent_Identity=50, Blast_Score=212, Evalue=6e-56,
Organism=Escherichia coli, GI87081872, Length=232, Percent_Identity=47.8448275862069, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI1786524, Length=340, Percent_Identity=37.3529411764706, Blast_Score=188, Evalue=6e-49,
Organism=Escherichia coli, GI1787583, Length=236, Percent_Identity=38.9830508474576, Blast_Score=164, Evalue=2e-41,
Organism=Escherichia coli, GI87081858, Length=225, Percent_Identity=36.8888888888889, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1789828, Length=234, Percent_Identity=36.7521367521368, Blast_Score=127, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR004096
- InterPro:   IPR010523
- ProDom:   PD485437 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat; PF02830 V4R; PF06505 XylR_N [H]

EC number: NA

Molecular weight: Translated: 64166; Mature: 64035

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPTTHAAPSATVRADGPDDRTLTEHLRFSPDAGHIVLFEQRMLLMHASSFAELRRELIE
CCCCCCCCCCCEEECCCCCCCHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHH
QLGTGKARELFTRLGYQQGFEDGQRLRALCGTDRDRMLELGPRLREIEGFVRNQPIDAMQ
HHCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHCCCCCCEE
FDLEGGEFWGDYYWTSSWEAEAHLKHCGVFGEPACWMMVGYASGCCTAILGQPVLWREIE
EECCCCCEECCCEECCCCCHHHHHHHCCCCCCCHHHHEEHHHHHHHHHHHCCCHHHHHHH
CVAMGHERCRVVGRPLAAWDDLSEHETNFLKIESFVRTPPKARPTRSAPAKVCVPGEFDD
HHHHCHHHHHHHCCCCHHHCCCHHHCCCCEEHHHHHCCCCCCCCCCCCCCEEEECCCCHH
FVGTSAGFNAVANLVRRVGVTDSTVLFRGESGVGKERFARALHSVSRRHEQPMVSINCAA
HCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEECC
IPPDLVESELFGVEKGAFTGADHSRPGRFERAHGGTLFLDEISSLPLPAQGKLLRVLQER
CCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHCCCCCCCHHHHHHHHHH
EIERVGDVRVRKVDVRLVAASNRDLRDEVEAGRFREDLFYRLNVFPIVIPPLRERLEDIP
HHHHHCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHEEEEEEEEECHHHHHHHHHH
LLVALFLERCNRRCGKRVAGLTTRAYDALWDYHWPGNVRELENMVERAVILADDDGKIDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHEEEEECCCCCEEH
QHLFSGGEQLKLRSLSVGAHGELVPRAGEASDQCKRLADDLLARLPSFEQIESLLFERAM
HHHHCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ERSDGNISAAARLLRLRRGQVEYRLKKRES
HCCCCCHHHHHHHHHHHCCCHHHHHHCCCC
>Mature Secondary Structure 
PPTTHAAPSATVRADGPDDRTLTEHLRFSPDAGHIVLFEQRMLLMHASSFAELRRELIE
CCCCCCCCCCEEECCCCCCCHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHH
QLGTGKARELFTRLGYQQGFEDGQRLRALCGTDRDRMLELGPRLREIEGFVRNQPIDAMQ
HHCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHCCCCCCEE
FDLEGGEFWGDYYWTSSWEAEAHLKHCGVFGEPACWMMVGYASGCCTAILGQPVLWREIE
EECCCCCEECCCEECCCCCHHHHHHHCCCCCCCHHHHEEHHHHHHHHHHHCCCHHHHHHH
CVAMGHERCRVVGRPLAAWDDLSEHETNFLKIESFVRTPPKARPTRSAPAKVCVPGEFDD
HHHHCHHHHHHHCCCCHHHCCCHHHCCCCEEHHHHHCCCCCCCCCCCCCCEEEECCCCHH
FVGTSAGFNAVANLVRRVGVTDSTVLFRGESGVGKERFARALHSVSRRHEQPMVSINCAA
HCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEECC
IPPDLVESELFGVEKGAFTGADHSRPGRFERAHGGTLFLDEISSLPLPAQGKLLRVLQER
CCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHCCCCCCCHHHHHHHHHH
EIERVGDVRVRKVDVRLVAASNRDLRDEVEAGRFREDLFYRLNVFPIVIPPLRERLEDIP
HHHHHCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHEEEEEEEEECHHHHHHHHHH
LLVALFLERCNRRCGKRVAGLTTRAYDALWDYHWPGNVRELENMVERAVILADDDGKIDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHEEEEECCCCCEEH
QHLFSGGEQLKLRSLSVGAHGELVPRAGEASDQCKRLADDLLARLPSFEQIESLLFERAM
HHHHCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ERSDGNISAAARLLRLRRGQVEYRLKKRES
HCCCCCHHHHHHHHHHHCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3169574; 2993247; 2430049 [H]