Click here to switch to the map view.

The map label for this gene is paaE [H]

Identifier: 124266184

GI number: 124266184

Start: 1052251

End: 1053336

Strand: Direct

Name: paaE [H]

Synonym: Mpe_A0991

Alternate gene names: 124266184

Gene position: 1052251-1053336 (Clockwise)

Preceding gene: 124266183

Following gene: 124266185

Centisome position: 26.02

GC content: 69.43

Gene sequence:

>1086_bases
ATGAGCCTGCTTTTCCATCCGTTGCGCGTGCGTGCCATCGAGCCCGACACGGCCGAGGCCGTGGTGGTGACGTTCGACGT
GCCGCCTGCGCTGCGCGAGGTGTTCGGCTTCACGCAGGGCCAGTACCTCACGCTGCGCAAGGAGATCGACGGGCAGGACC
TGCGCCGCTCCTACTCCATCTGCGCCGGTGTCGACGACGGCCAATTGCGCGTGGGCGTGCGCAAGGTGCGCGGCGGCGTG
TTCTCGAACTGGATCAACGAGCACCTGCGCACCGGCGACGTGGTCCAGGTCATGGCGCCGCAGGGCCGCTTCTTCGTGCC
GCTCGATCCGGCGTCGAAGCGCCACCACCTGGGCATCGCCGGCGGCAGCGGCATCACGCCCATCCTGTCGATCATGAAGA
CGGTGCTGGCGCGTGAGCCGCACAGCCGCTTCACGCTGATCTACGGCAACCGGCTGCTGAACTCGACGATGTTCAAGGAG
GAGCTCGAGGACCTGAAGAACCGCTACCTGACGCGGCTGGTGCTGCACCACGTGTTCTCCGACGAGCACACCGACGCGCC
GCTGAACCGCGGCGTGATGAACCGCCACAAGATCGGCGAGTTCCTGTCCGTCCTGGTACCGGCCGCCGGCATCGCCCACG
CCTATGTCTGCGGCCCGTTCCAGATGAACGACGAGGCCGAGGCGGCGCTGCGGGCGGCCGGCGTGCCGGAGGACCGCATC
CACATCGAACGCTTCGGCGTCGCGCAGCCGGCCGGCGGCACGGCCGACGCGGTGGTCCACGAGGCCCGGCCCGGCGACGC
CGAGCAGGCGAAGGTCACGATCATCCGCGACGGCCTGCGGCGCGAGATCTCGTTCACCAAGGGACAACCCAGCCTGCTCG
ACGCGGCCTCGGCGGCCGGGCTCGAGGTGCCGTTCTCGTGCACGTCCGGGGTCTGCGGCACCTGCCGGGCGAAGCTGATC
GAGGGGCAGGTCCGCATGGAGCGAAACTTCGCGCTGGACAGGAAGGAGGTGGCCGCCGGCTTCGTCCTCACCTGCCAGGC
GCACCCGCTGACCGACCGCGTGGTGCTCTCCTTCGACGAACGCTGA

Upstream 100 bases:

>100_bases
GCTGTCGGCCTTCGGGTCGACCGCCTGCAAGGCGCTGTACCGCTGCCTGAGCTGCCGCGAGCCGTTCGAGCACTTCAAGC
CGCTCTGATCGCACTGGTTC

Downstream 100 bases:

>100_bases
GACGAGGACACCCGATGGCCCGTGGCCGCCTGCCCGGATATGCAGACCAGCTCGACCTGATCCTGGAGCACGCGGCGCGC
CTGTTCGCGCGGCGCGGCTA

Product: putative ring-hydroxylation complex protein 4

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MSLLFHPLRVRAIEPDTAEAVVVTFDVPPALREVFGFTQGQYLTLRKEIDGQDLRRSYSICAGVDDGQLRVGVRKVRGGV
FSNWINEHLRTGDVVQVMAPQGRFFVPLDPASKRHHLGIAGGSGITPILSIMKTVLAREPHSRFTLIYGNRLLNSTMFKE
ELEDLKNRYLTRLVLHHVFSDEHTDAPLNRGVMNRHKIGEFLSVLVPAAGIAHAYVCGPFQMNDEAEAALRAAGVPEDRI
HIERFGVAQPAGGTADAVVHEARPGDAEQAKVTIIRDGLRREISFTKGQPSLLDAASAAGLEVPFSCTSGVCGTCRAKLI
EGQVRMERNFALDRKEVAAGFVLTCQAHPLTDRVVLSFDER

Sequences:

>Translated_361_residues
MSLLFHPLRVRAIEPDTAEAVVVTFDVPPALREVFGFTQGQYLTLRKEIDGQDLRRSYSICAGVDDGQLRVGVRKVRGGV
FSNWINEHLRTGDVVQVMAPQGRFFVPLDPASKRHHLGIAGGSGITPILSIMKTVLAREPHSRFTLIYGNRLLNSTMFKE
ELEDLKNRYLTRLVLHHVFSDEHTDAPLNRGVMNRHKIGEFLSVLVPAAGIAHAYVCGPFQMNDEAEAALRAAGVPEDRI
HIERFGVAQPAGGTADAVVHEARPGDAEQAKVTIIRDGLRREISFTKGQPSLLDAASAAGLEVPFSCTSGVCGTCRAKLI
EGQVRMERNFALDRKEVAAGFVLTCQAHPLTDRVVLSFDER
>Mature_360_residues
SLLFHPLRVRAIEPDTAEAVVVTFDVPPALREVFGFTQGQYLTLRKEIDGQDLRRSYSICAGVDDGQLRVGVRKVRGGVF
SNWINEHLRTGDVVQVMAPQGRFFVPLDPASKRHHLGIAGGSGITPILSIMKTVLAREPHSRFTLIYGNRLLNSTMFKEE
LEDLKNRYLTRLVLHHVFSDEHTDAPLNRGVMNRHKIGEFLSVLVPAAGIAHAYVCGPFQMNDEAEAALRAAGVPEDRIH
IERFGVAQPAGGTADAVVHEARPGDAEQAKVTIIRDGLRREISFTKGQPSLLDAASAAGLEVPFSCTSGVCGTCRAKLIE
GQVRMERNFALDRKEVAAGFVLTCQAHPLTDRVVLSFDER

Specific function: May be part of a multicomponent oxygenase involved in phenylacetyl-CoA hydroxylation [H]

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1787658, Length=357, Percent_Identity=42.8571428571429, Blast_Score=297, Evalue=7e-82,
Organism=Escherichia coli, GI1787098, Length=325, Percent_Identity=24.6153846153846, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788104, Length=358, Percent_Identity=24.3016759776536, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788903, Length=253, Percent_Identity=27.6679841897233, Blast_Score=74, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322146, Length=202, Percent_Identity=30.6930693069307, Blast_Score=81, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6323510, Length=209, Percent_Identity=27.7511961722488, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR001709
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR011884
- InterPro:   IPR001221
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 39680; Mature: 39549

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLFHPLRVRAIEPDTAEAVVVTFDVPPALREVFGFTQGQYLTLRKEIDGQDLRRSYSI
CCCEECCEEEEEECCCCCCEEEEEECCCHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHH
CAGVDDGQLRVGVRKVRGGVFSNWINEHLRTGDVVQVMAPQGRFFVPLDPASKRHHLGIA
HCCCCCCCEEHHHHHHHCHHHHHHHHHHCCCCCEEEEECCCCCEEEECCCCCCCCEEEEC
GGSGITPILSIMKTVLAREPHSRFTLIYGNRLLNSTMFKEELEDLKNRYLTRLVLHHVFS
CCCCHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DEHTDAPLNRGVMNRHKIGEFLSVLVPAAGIAHAYVCGPFQMNDEAEAALRAAGVPEDRI
CCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHCCCCHHHE
HIERFGVAQPAGGTADAVVHEARPGDAEQAKVTIIRDGLRREISFTKGQPSLLDAASAAG
EEEECCCCCCCCCCHHHHEECCCCCCCCCEEEEEEHHCHHHHCCCCCCCCHHHHHHCCCC
LEVPFSCTSGVCGTCRAKLIEGQVRMERNFALDRKEVAAGFVLTCQAHPLTDRVVLSFDE
CCCCCCCCCCCCHHHHHHHHHCHHHHHHCCCCCHHHHCCCEEEEEECCCCCCEEEEEECC
R
C
>Mature Secondary Structure 
SLLFHPLRVRAIEPDTAEAVVVTFDVPPALREVFGFTQGQYLTLRKEIDGQDLRRSYSI
CCEECCEEEEEECCCCCCEEEEEECCCHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHH
CAGVDDGQLRVGVRKVRGGVFSNWINEHLRTGDVVQVMAPQGRFFVPLDPASKRHHLGIA
HCCCCCCCEEHHHHHHHCHHHHHHHHHHCCCCCEEEEECCCCCEEEECCCCCCCCEEEEC
GGSGITPILSIMKTVLAREPHSRFTLIYGNRLLNSTMFKEELEDLKNRYLTRLVLHHVFS
CCCCHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DEHTDAPLNRGVMNRHKIGEFLSVLVPAAGIAHAYVCGPFQMNDEAEAALRAAGVPEDRI
CCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHCCCCHHHE
HIERFGVAQPAGGTADAVVHEARPGDAEQAKVTIIRDGLRREISFTKGQPSLLDAASAAG
EEEECCCCCCCCCCHHHHEECCCCCCCCCEEEEEEHHCHHHHCCCCCCCCHHHHHHCCCC
LEVPFSCTSGVCGTCRAKLIEGQVRMERNFALDRKEVAAGFVLTCQAHPLTDRVVLSFDE
CCCCCCCCCCCCHHHHHHHHHCHHHHHHCCCCCHHHHCCCEEEEEECCCCCCEEEEEECC
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: FAD [C]

Metal ions: Iron-Sulfur [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]