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The map label for this gene is prmA [H]

Identifier: 124266143

GI number: 124266143

Start: 1005875

End: 1007542

Strand: Direct

Name: prmA [H]

Synonym: Mpe_A0950

Alternate gene names: 124266143

Gene position: 1005875-1007542 (Clockwise)

Preceding gene: 124266142

Following gene: 124266144

Centisome position: 24.87

GC content: 64.81

Gene sequence:

>1668_bases
ATGTCAGCAGGTTTGACGCTCAACAAGATCACGTCCCAGAAAGGGATCAGCGTGGCCGAGGCGGCTCGGCGCATCGCCGA
CCTCGGATGGCAGCCCAGCTATGTCCAGGAAGCGATGACCTTCCCGACCGATTACAAGATCGGCAAGGCCCCGCGCGACC
CGATGAAGCAGGTGCTGCGCTCCTACTTCCCGATGCAGGAGGAGAAGGACAACCGCGTGTACGGCGCGCTCGACGCGGCG
CTGCGCGGCGACATGTTCCGCAACACCAAGCCGCGCTGGGTCGAGTGGATGAAGCTGTTCCTGGCGATCATCCCCTTCCC
CGAGATCTCGGCGGCACGCTCGATGTCCATGCTCGGCCGCCTCGCCCCGGGCGAGGAGCTGCGCACCGGCTTCACGATGC
AGATGGTCGACGAGTTCCGCCATTCCACGATTCAGATGAACCTGAAGAAGTGGTACATGGAGAACTACATCGACCCGGCC
GGCTTCGACATCACCGAGGCCGCGTTCGGCAAGTGCTACGCCACCACCATCGGCCGCCAGTTCGCCGAAGGCTTCCTGAC
CGGTGACGCGCTGACGGCCGCGAACATCTACCTGCAGGTCGTCGCCGAGACCGGCTTCACCAACACGCTGTTCGTCGCGA
TGCCGTCGGAAGCTGCCCGCAACGGCGACTACGCGCTGTCGTCGGTGTTCCTGTCGGTGCAGTCGGACGAGTCGCGCCAC
ATCGGCAACGGCCACTCGCTGCTGATGTCGGTGGTCAACGACCCCGACAACCACCTGCTGCTCGAGCGCGACATCCGCTA
CGCGTTCTGGCAGAACCACGCGATCGTCGACGCCGCCATCGGCACGATCATCGAGTACGGCACCACCGACCGCAGCAAGA
ACAAGGAGTCCTACGCCGAGCTCTGGCACCGCTGGATCTACGAGGACTACTACCGCACCTACCTGCTCCCGCTCGAGAAG
TACGGCGTCAAGATCCACCACGACGACGTCTCCGCCGCGTGGGACCGCCTGGTCAAGAAGAACTACGTGCACAAGGTCGC
GCAGTTCTTCGCGGTCGGCTGGCCCGCCAACTTCTGGCGCATCGAAGCCCAGACCGAGAAGGACTTCGAGTGGTTCGAGC
ACAAGTACCCGGGCTGGTACGCCGAGTTCGGCGATTTCTGGAAGTGGTACGAGCGCAAGAGCGTGCCGGGCGAGACCAAC
ATGCTGTTCGACCAGGAGAACGGCTACGTCTACCCGCACCGCTGCTGGAGCTGCATGGTGCCGGCGGTGATCCGTGAGGA
GCTGGTGGTCGACGAGGTCGACGGCAAGCTCTACACCTACTGCTCCGAGCTGTGCCGCTGGACCCACAAGACGGCCTTCG
CCGCCGAGTACGAGGGCCGCCCGACGCCGGCGATGGGCCGCTTCAGCGGTCGCCGCGAATGGGAAGAGTGCTACCACGGC
TGGGACCTGGCCGACGCGATCAAGGACCTCGGCTTCGTCCGCTCGGACGGCAAGACGCTGGTCTCGCAGCCCCACCTGCG
CTTCGACGACAAGCACATGTGGACGCTGGATCACGTGCGGGGCCACCAGCTCCAGAGCCCGCTCGTGCTTCTGCGCGAGA
TGACGCCCGAGGCGCGTGAGAAGCACATCGCCTCCTACCGCGCCGGCTTCAAGATCAAGCCGTTCTGA

Upstream 100 bases:

>100_bases
AGAGGAGGGGCCCTGGCCCAAGGACAGGTCGGCGGCACGACCGCGCGGCCTCGACGCACAGCAAACCGGTCCGAACGGAT
CAGCAGTAAAGGAGACCTTC

Downstream 100 bases:

>100_bases
CGCGGTTCTCAGTGGTCCCGGGCGGCGGTGCCGCCCGGGGCGGACCAGATTATTCGGGGACAGACATGTCTGCAAAAACA
GTCCACACCGTTCGTTTCGA

Product: propane monoxygenase hydroxylase large subunit

Products: NA

Alternate protein names: Methane hydroxylase [H]

Number of amino acids: Translated: 555; Mature: 554

Protein sequence:

>555_residues
MSAGLTLNKITSQKGISVAEAARRIADLGWQPSYVQEAMTFPTDYKIGKAPRDPMKQVLRSYFPMQEEKDNRVYGALDAA
LRGDMFRNTKPRWVEWMKLFLAIIPFPEISAARSMSMLGRLAPGEELRTGFTMQMVDEFRHSTIQMNLKKWYMENYIDPA
GFDITEAAFGKCYATTIGRQFAEGFLTGDALTAANIYLQVVAETGFTNTLFVAMPSEAARNGDYALSSVFLSVQSDESRH
IGNGHSLLMSVVNDPDNHLLLERDIRYAFWQNHAIVDAAIGTIIEYGTTDRSKNKESYAELWHRWIYEDYYRTYLLPLEK
YGVKIHHDDVSAAWDRLVKKNYVHKVAQFFAVGWPANFWRIEAQTEKDFEWFEHKYPGWYAEFGDFWKWYERKSVPGETN
MLFDQENGYVYPHRCWSCMVPAVIREELVVDEVDGKLYTYCSELCRWTHKTAFAAEYEGRPTPAMGRFSGRREWEECYHG
WDLADAIKDLGFVRSDGKTLVSQPHLRFDDKHMWTLDHVRGHQLQSPLVLLREMTPEAREKHIASYRAGFKIKPF

Sequences:

>Translated_555_residues
MSAGLTLNKITSQKGISVAEAARRIADLGWQPSYVQEAMTFPTDYKIGKAPRDPMKQVLRSYFPMQEEKDNRVYGALDAA
LRGDMFRNTKPRWVEWMKLFLAIIPFPEISAARSMSMLGRLAPGEELRTGFTMQMVDEFRHSTIQMNLKKWYMENYIDPA
GFDITEAAFGKCYATTIGRQFAEGFLTGDALTAANIYLQVVAETGFTNTLFVAMPSEAARNGDYALSSVFLSVQSDESRH
IGNGHSLLMSVVNDPDNHLLLERDIRYAFWQNHAIVDAAIGTIIEYGTTDRSKNKESYAELWHRWIYEDYYRTYLLPLEK
YGVKIHHDDVSAAWDRLVKKNYVHKVAQFFAVGWPANFWRIEAQTEKDFEWFEHKYPGWYAEFGDFWKWYERKSVPGETN
MLFDQENGYVYPHRCWSCMVPAVIREELVVDEVDGKLYTYCSELCRWTHKTAFAAEYEGRPTPAMGRFSGRREWEECYHG
WDLADAIKDLGFVRSDGKTLVSQPHLRFDDKHMWTLDHVRGHQLQSPLVLLREMTPEAREKHIASYRAGFKIKPF
>Mature_554_residues
SAGLTLNKITSQKGISVAEAARRIADLGWQPSYVQEAMTFPTDYKIGKAPRDPMKQVLRSYFPMQEEKDNRVYGALDAAL
RGDMFRNTKPRWVEWMKLFLAIIPFPEISAARSMSMLGRLAPGEELRTGFTMQMVDEFRHSTIQMNLKKWYMENYIDPAG
FDITEAAFGKCYATTIGRQFAEGFLTGDALTAANIYLQVVAETGFTNTLFVAMPSEAARNGDYALSSVFLSVQSDESRHI
GNGHSLLMSVVNDPDNHLLLERDIRYAFWQNHAIVDAAIGTIIEYGTTDRSKNKESYAELWHRWIYEDYYRTYLLPLEKY
GVKIHHDDVSAAWDRLVKKNYVHKVAQFFAVGWPANFWRIEAQTEKDFEWFEHKYPGWYAEFGDFWKWYERKSVPGETNM
LFDQENGYVYPHRCWSCMVPAVIREELVVDEVDGKLYTYCSELCRWTHKTAFAAEYEGRPTPAMGRFSGRREWEECYHGW
DLADAIKDLGFVRSDGKTLVSQPHLRFDDKHMWTLDHVRGHQLQSPLVLLREMTPEAREKHIASYRAGFKIKPF

Specific function: Responsible for the initial oxygenation of methane to methanol in methanotrophs. It also catalyzes the monohydroxylation of a variety of unactivated alkenes, alicyclic, aromatic and heterocyclic compounds [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009078
- InterPro:   IPR003430
- InterPro:   IPR012348 [H]

Pfam domain/function: PF02332 Phenol_Hydrox [H]

EC number: =1.14.13.25 [H]

Molecular weight: Translated: 64374; Mature: 64242

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAGLTLNKITSQKGISVAEAARRIADLGWQPSYVQEAMTFPTDYKIGKAPRDPMKQVLR
CCCCCCHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
SYFPMQEEKDNRVYGALDAALRGDMFRNTKPRWVEWMKLFLAIIPFPEISAARSMSMLGR
HHCCCCCCCCCCCHHHHHHHHHCHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
LAPGEELRTGFTMQMVDEFRHSTIQMNLKKWYMENYIDPAGFDITEAAFGKCYATTIGRQ
CCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
FAEGFLTGDALTAANIYLQVVAETGFTNTLFVAMPSEAARNGDYALSSVFLSVQSDESRH
HHHHHCCCCHHHHHHHHEEEEECCCCCCEEEEEECCHHHCCCCCEEEHHEEEEECCCCCC
IGNGHSLLMSVVNDPDNHLLLERDIRYAFWQNHAIVDAAIGTIIEYGTTDRSKNKESYAE
CCCHHHHHHHHHCCCCCCEEEEHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHH
LWHRWIYEDYYRTYLLPLEKYGVKIHHDDVSAAWDRLVKKNYVHKVAQFFAVGWPANFWR
HHHHHHHHHHHHHHHEEHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
IEAQTEKDFEWFEHKYPGWYAEFGDFWKWYERKSVPGETNMLFDQENGYVYPHRCWSCMV
EECCCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEECHHHHHHHHH
PAVIREELVVDEVDGKLYTYCSELCRWTHKTAFAAEYEGRPTPAMGRFSGRREWEECYHG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCHHHHHHHCC
WDLADAIKDLGFVRSDGKTLVSQPHLRFDDKHMWTLDHVRGHQLQSPLVLLREMTPEARE
CCHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCEEEEHHHCCCCCCCHHHHHHHCCHHHHH
KHIASYRAGFKIKPF
HHHHHHHCCCEECCC
>Mature Secondary Structure 
SAGLTLNKITSQKGISVAEAARRIADLGWQPSYVQEAMTFPTDYKIGKAPRDPMKQVLR
CCCCCHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
SYFPMQEEKDNRVYGALDAALRGDMFRNTKPRWVEWMKLFLAIIPFPEISAARSMSMLGR
HHCCCCCCCCCCCHHHHHHHHHCHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
LAPGEELRTGFTMQMVDEFRHSTIQMNLKKWYMENYIDPAGFDITEAAFGKCYATTIGRQ
CCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
FAEGFLTGDALTAANIYLQVVAETGFTNTLFVAMPSEAARNGDYALSSVFLSVQSDESRH
HHHHHCCCCHHHHHHHHEEEEECCCCCCEEEEEECCHHHCCCCCEEEHHEEEEECCCCCC
IGNGHSLLMSVVNDPDNHLLLERDIRYAFWQNHAIVDAAIGTIIEYGTTDRSKNKESYAE
CCCHHHHHHHHHCCCCCCEEEEHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHH
LWHRWIYEDYYRTYLLPLEKYGVKIHHDDVSAAWDRLVKKNYVHKVAQFFAVGWPANFWR
HHHHHHHHHHHHHHHEEHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
IEAQTEKDFEWFEHKYPGWYAEFGDFWKWYERKSVPGETNMLFDQENGYVYPHRCWSCMV
EECCCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEECHHHHHHHHH
PAVIREELVVDEVDGKLYTYCSELCRWTHKTAFAAEYEGRPTPAMGRFSGRREWEECYHG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCHHHHHHHCC
WDLADAIKDLGFVRSDGKTLVSQPHLRFDDKHMWTLDHVRGHQLQSPLVLLREMTPEARE
CCHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCEEEEHHHCCCCCCCHHHHHHHCCHHHHH
KHIASYRAGFKIKPF
HHHHHHHCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2205538; 8255292; 9432288; 9329079; 11456616 [H]