Click here to switch to the map view.

The map label for this gene is ubiE [H]

Identifier: 124266125

GI number: 124266125

Start: 986734

End: 987387

Strand: Direct

Name: ubiE [H]

Synonym: Mpe_A0932

Alternate gene names: 124266125

Gene position: 986734-987387 (Clockwise)

Preceding gene: 124266124

Following gene: 124266126

Centisome position: 24.4

GC content: 70.03

Gene sequence:

>654_bases
ATGAGCAACTTCTACAACGATCACATCCTGCCGCGCGCGGTCGATGTCATCTGTGGTCTGCCCAGCTTCGAGAGCGGGCG
CGCGGAGCTGGTGCCGCAGGCCTCGGGCCGGGTGCTCGAGATCGGCATGGGCACGGGACGCAACCTGCCGTACTACCGCG
CTGCCGGACTGCAATGCCTGTGCGGTGTCGATCCCGGCCTGCATGCCCTGGCCCGGCGCCGGGCCGAGGCCGCAGGCCTG
GAGATCCAGGCGCTGCCGCTGTCGGCCGAACGCATCCCGGTGGACGACCGCAGCTTCGATTGCGTGGTGTCCACCTTCAC
GCTCTGCACCATTCCCGATGCGGCCCAGGCGCTGAAGGAGGTCTACCGCGTGCTGGTGCCGGGCGGGCGCCTGCTGTTCC
TGGAGCACGGTGCCGCGCCTGACGCGTCGGTGCGGCGCTGGCAGGACCGCCTCACGCCGTACTGGAGGCCGCTGGCCGGC
GGCTGCCATCTCAACCGCGAGATGCCGGGGCTGATCGAGTCGGCGGGCTTCTGGATCGAAAGTCTGCAGCGCCGCTACCG
GCCCGGGCCGAGATGGCTGACCAGTCTGTACTCGGGGGTCGCTACACGGCCCCGTTCTCCGGGTCCGACGGATCGAGGCT
CGTCGCCGGATTGA

Upstream 100 bases:

>100_bases
GCCCAGGCCCGCGCCGGCCCGGTTCGTCAGTTGCCTGTCGTAGTGGCAGGCCGGGGCTGCGGCGTATGCTCGCCGCCACC
GCAATCCTCGGTGCGCACGG

Downstream 100 bases:

>100_bases
TCCACCAGGGATGCTGTGGCGGGCGTCGTAGACGCTGCCCGACGGGCTGGGGGTCCGCAGTTCGCCGCAGCTGGCCCTGG
GAATCCTCCCGGTCGCGATG

Product: putative methyltransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MSNFYNDHILPRAVDVICGLPSFESGRAELVPQASGRVLEIGMGTGRNLPYYRAAGLQCLCGVDPGLHALARRRAEAAGL
EIQALPLSAERIPVDDRSFDCVVSTFTLCTIPDAAQALKEVYRVLVPGGRLLFLEHGAAPDASVRRWQDRLTPYWRPLAG
GCHLNREMPGLIESAGFWIESLQRRYRPGPRWLTSLYSGVATRPRSPGPTDRGSSPD

Sequences:

>Translated_217_residues
MSNFYNDHILPRAVDVICGLPSFESGRAELVPQASGRVLEIGMGTGRNLPYYRAAGLQCLCGVDPGLHALARRRAEAAGL
EIQALPLSAERIPVDDRSFDCVVSTFTLCTIPDAAQALKEVYRVLVPGGRLLFLEHGAAPDASVRRWQDRLTPYWRPLAG
GCHLNREMPGLIESAGFWIESLQRRYRPGPRWLTSLYSGVATRPRSPGPTDRGSSPD
>Mature_216_residues
SNFYNDHILPRAVDVICGLPSFESGRAELVPQASGRVLEIGMGTGRNLPYYRAAGLQCLCGVDPGLHALARRRAEAAGLE
IQALPLSAERIPVDDRSFDCVVSTFTLCTIPDAAQALKEVYRVLVPGGRLLFLEHGAAPDASVRRWQDRLTPYWRPLAGG
CHLNREMPGLIESAGFWIESLQRRYRPGPRWLTSLYSGVATRPRSPGPTDRGSSPD

Specific function: Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiE family [H]

Homologues:

Organism=Homo sapiens, GI164663805, Length=187, Percent_Identity=35.8288770053476, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI89145417, Length=179, Percent_Identity=32.9608938547486, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004033 [H]

Pfam domain/function: PF01209 Ubie_methyltran [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 23811; Mature: 23680

Theoretical pI: Translated: 8.37; Mature: 8.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNFYNDHILPRAVDVICGLPSFESGRAELVPQASGRVLEIGMGTGRNLPYYRAAGLQCL
CCCCCCCCCHHHHHHHHHCCCCCCCCCCEECCCCCCCEEEEECCCCCCCCCCHHCCCEEE
CGVDPGLHALARRRAEAAGLEIQALPLSAERIPVDDRSFDCVVSTFTLCTIPDAAQALKE
ECCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHH
VYRVLVPGGRLLFLEHGAAPDASVRRWQDRLTPYWRPLAGGCHLNREMPGLIESAGFWIE
HHHHHCCCCEEEEEECCCCCCHHHHHHHHHCCHHHCCCCCCEECCCCCCHHHHHHHHHHH
SLQRRYRPGPRWLTSLYSGVATRPRSPGPTDRGSSPD
HHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SNFYNDHILPRAVDVICGLPSFESGRAELVPQASGRVLEIGMGTGRNLPYYRAAGLQCL
CCCCCCCCHHHHHHHHHCCCCCCCCCCEECCCCCCCEEEEECCCCCCCCCCHHCCCEEE
CGVDPGLHALARRRAEAAGLEIQALPLSAERIPVDDRSFDCVVSTFTLCTIPDAAQALKE
ECCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHH
VYRVLVPGGRLLFLEHGAAPDASVRRWQDRLTPYWRPLAGGCHLNREMPGLIESAGFWIE
HHHHHCCCCEEEEEECCCCCCHHHHHHHHHCCHHHCCCCCCEECCCCCCHHHHHHHHHHH
SLQRRYRPGPRWLTSLYSGVATRPRSPGPTDRGSSPD
HHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA