Click here to switch to the map view.

The map label for this gene is murA [H]

Identifier: 124266022

GI number: 124266022

Start: 869060

End: 870364

Strand: Direct

Name: murA [H]

Synonym: Mpe_A0829

Alternate gene names: 124266022

Gene position: 869060-870364 (Clockwise)

Preceding gene: 124266021

Following gene: 124266023

Centisome position: 21.49

GC content: 70.57

Gene sequence:

>1305_bases
ATGCAGGGCGGTGACGAGCACCGCACCATGGACAAACTCATCATTCGCGGCGGCCGCCGTCTCCACGGCGAGGTCGCGAT
CTCGGGCGCCAAGAACGCGGCGCTGCCGGAGCTGTGCGCTGCGCTGCTGACGGCCGAGCCGGTGCGCTTCTCGAACGTGC
CGCGCCTGCAGGACGTCTCGACCACGCTGAAGCTGCTGCGCAATATGGGTGCCGTCGCCGAGCGCAGCGAGAGCCGCCCC
GACGAAGTGACCATCGACGCCGGCCCGGTCAGCAGCCCCGAGGCCCCCTACGACCTGGTGAAGACCATGCGGGCGTCGAT
CCTGGTGCTGGGACCGCTGCTGGCGCGCTTCGGCGAGGCCACGGTGTCGCTGCCGGGCGGCTGCGCGATCGGCTCGCGGC
CGGTGGATCAGCACATCAAGGGCCTGCAGGCGATGGGCGCGCAGATCAGCGTCGAGCACGGCTACATCATCGCGAAGGCG
CCCAAGGCCTCGGGCGGGCTGCGCGGTGCGCGCATCACGACGGACATGGTGACCGTCACCGGCACCGAGAACCTGCTGAT
GGCCGCGACACTGGCCGACGGCGAGACCGTGCTCGAGAACGCCGCGCAGGAGCCCGAGATCCCCGACCTGGCCGAGATGC
TGATCTCGATGGGCGCGAAGATCGAGGGCCACGGCAGCAGCAAGATCCGCATCCAGGGCGTCGCGCAACTGCACGCGCCG
CGCGGCGGGCACCGCGTGGTGCCCGACCGCATCGAGGCCGGCACCTTCCTGTGCGCGGTGGCCGCGGCCGGCGGCGAGGT
GCTGCTGAAGCACGCGCGCGCCGACCACCTGGACGCGGTGATCGACAAGCTGCGCGAGGCCGGCGTCCGCATCGAGGCCG
GCAGCGACTGGATCCGCGTGGCCTCCGACGGCAAGCTGAAGGCGGTGGGCTTCCGCACCAGCGAGTACCCGGCCTTCCCG
ACCGACATGCAGGCGCAGTTCATGGCGCTCGACTGCATTGCCGAGGGCACGGCGCGCGTCACCGAGACCATCTTCGAGAA
CCGCTTCATGCACGTCGATGAACTGGTGCGCCTGGGCGCGAAGATCGAGGTCGACGGCCACACGGCCATCGTCACCGGCG
TGCCGCAGCTGTCGGGCGCCACGGTGATGGCCACCGACCTGCGCGCCTCGGCCAGCCTGGTGATCGCCGGCCTGGTGGCC
AGCGGCGAGACCCTGGTCGACCGCATCTACCACCTGGACCGCGGCTACGACCAGATGGAAACGAAGCTGCGCGCCCTGGG
CGCGGACATCGAAAGAGTGAAATGA

Upstream 100 bases:

>100_bases
AGCCCCGCGCCGCCGCTGCCCACCACCACTGATCCACAAGCCGCCCTGTGGCGCGGCTTGTGCGCTCCCTCGTGGCGAGG
GCGGTCCGTGCAAGCGCGTG

Downstream 100 bases:

>100_bases
CAGTCCTCACGCGCACCTCGTTCGCTTCGCCCCGAGGGCGCGAGGCCTCCATCCGGGCGGCCCGGCGGGAGGCCCCATGA
GCATCACGCTCGCGCTGTCG

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MQGGDEHRTMDKLIIRGGRRLHGEVAISGAKNAALPELCAALLTAEPVRFSNVPRLQDVSTTLKLLRNMGAVAERSESRP
DEVTIDAGPVSSPEAPYDLVKTMRASILVLGPLLARFGEATVSLPGGCAIGSRPVDQHIKGLQAMGAQISVEHGYIIAKA
PKASGGLRGARITTDMVTVTGTENLLMAATLADGETVLENAAQEPEIPDLAEMLISMGAKIEGHGSSKIRIQGVAQLHAP
RGGHRVVPDRIEAGTFLCAVAAAGGEVLLKHARADHLDAVIDKLREAGVRIEAGSDWIRVASDGKLKAVGFRTSEYPAFP
TDMQAQFMALDCIAEGTARVTETIFENRFMHVDELVRLGAKIEVDGHTAIVTGVPQLSGATVMATDLRASASLVIAGLVA
SGETLVDRIYHLDRGYDQMETKLRALGADIERVK

Sequences:

>Translated_434_residues
MQGGDEHRTMDKLIIRGGRRLHGEVAISGAKNAALPELCAALLTAEPVRFSNVPRLQDVSTTLKLLRNMGAVAERSESRP
DEVTIDAGPVSSPEAPYDLVKTMRASILVLGPLLARFGEATVSLPGGCAIGSRPVDQHIKGLQAMGAQISVEHGYIIAKA
PKASGGLRGARITTDMVTVTGTENLLMAATLADGETVLENAAQEPEIPDLAEMLISMGAKIEGHGSSKIRIQGVAQLHAP
RGGHRVVPDRIEAGTFLCAVAAAGGEVLLKHARADHLDAVIDKLREAGVRIEAGSDWIRVASDGKLKAVGFRTSEYPAFP
TDMQAQFMALDCIAEGTARVTETIFENRFMHVDELVRLGAKIEVDGHTAIVTGVPQLSGATVMATDLRASASLVIAGLVA
SGETLVDRIYHLDRGYDQMETKLRALGADIERVK
>Mature_434_residues
MQGGDEHRTMDKLIIRGGRRLHGEVAISGAKNAALPELCAALLTAEPVRFSNVPRLQDVSTTLKLLRNMGAVAERSESRP
DEVTIDAGPVSSPEAPYDLVKTMRASILVLGPLLARFGEATVSLPGGCAIGSRPVDQHIKGLQAMGAQISVEHGYIIAKA
PKASGGLRGARITTDMVTVTGTENLLMAATLADGETVLENAAQEPEIPDLAEMLISMGAKIEGHGSSKIRIQGVAQLHAP
RGGHRVVPDRIEAGTFLCAVAAAGGEVLLKHARADHLDAVIDKLREAGVRIEAGSDWIRVASDGKLKAVGFRTSEYPAFP
TDMQAQFMALDCIAEGTARVTETIFENRFMHVDELVRLGAKIEVDGHTAIVTGVPQLSGATVMATDLRASASLVIAGLVA
SGETLVDRIYHLDRGYDQMETKLRALGADIERVK

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=426, Percent_Identity=58.9201877934272, Blast_Score=477, Evalue=1e-136,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 46034; Mature: 46034

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQGGDEHRTMDKLIIRGGRRLHGEVAISGAKNAALPELCAALLTAEPVRFSNVPRLQDVS
CCCCHHHHHHHHHHHHCCCEEECEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHH
TTLKLLRNMGAVAERSESRPDEVTIDAGPVSSPEAPYDLVKTMRASILVLGPLLARFGEA
HHHHHHHHHCHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
TVSLPGGCAIGSRPVDQHIKGLQAMGAQISVEHGYIIAKAPKASGGLRGARITTDMVTVT
EEECCCCCCCCCCCHHHHHHHHHHCCCEEEEECCEEEEECCCCCCCCCCCEEEEEEEEEE
GTENLLMAATLADGETVLENAAQEPEIPDLAEMLISMGAKIEGHGSSKIRIQGVAQLHAP
CCCCEEEEEEECCCHHHHHHCCCCCCCHHHHHHHHHCCCEEECCCCCEEEEEEEEEECCC
RGGHRVVPDRIEAGTFLCAVAAAGGEVLLKHARADHLDAVIDKLREAGVRIEAGSDWIRV
CCCCCCCCCHHCCCCEEEEEHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEE
ASDGKLKAVGFRTSEYPAFPTDMQAQFMALDCIAEGTARVTETIFENRFMHVDELVRLGA
ECCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHCCC
KIEVDGHTAIVTGVPQLSGATVMATDLRASASLVIAGLVASGETLVDRIYHLDRGYDQME
EEEECCCEEEEECCCCCCCCEEEEECCCCCHHEEEEEHHHCCHHHHHHHHHHCCCHHHHH
TKLRALGADIERVK
HHHHHHCCHHHHCC
>Mature Secondary Structure
MQGGDEHRTMDKLIIRGGRRLHGEVAISGAKNAALPELCAALLTAEPVRFSNVPRLQDVS
CCCCHHHHHHHHHHHHCCCEEECEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHH
TTLKLLRNMGAVAERSESRPDEVTIDAGPVSSPEAPYDLVKTMRASILVLGPLLARFGEA
HHHHHHHHHCHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
TVSLPGGCAIGSRPVDQHIKGLQAMGAQISVEHGYIIAKAPKASGGLRGARITTDMVTVT
EEECCCCCCCCCCCHHHHHHHHHHCCCEEEEECCEEEEECCCCCCCCCCCEEEEEEEEEE
GTENLLMAATLADGETVLENAAQEPEIPDLAEMLISMGAKIEGHGSSKIRIQGVAQLHAP
CCCCEEEEEEECCCHHHHHHCCCCCCCHHHHHHHHHCCCEEECCCCCEEEEEEEEEECCC
RGGHRVVPDRIEAGTFLCAVAAAGGEVLLKHARADHLDAVIDKLREAGVRIEAGSDWIRV
CCCCCCCCCHHCCCCEEEEEHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEE
ASDGKLKAVGFRTSEYPAFPTDMQAQFMALDCIAEGTARVTETIFENRFMHVDELVRLGA
ECCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHCCC
KIEVDGHTAIVTGVPQLSGATVMATDLRASASLVIAGLVASGETLVDRIYHLDRGYDQME
EEEECCCEEEEECCCCCCCCEEEEECCCCCHHEEEEEHHHCCHHHHHHHHHHCCCHHHHH
TKLRALGADIERVK
HHHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA