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The map label for this gene is mcp [H]

Identifier: 124266015

GI number: 124266015

Start: 863422

End: 864924

Strand: Direct

Name: mcp [H]

Synonym: Mpe_A0822

Alternate gene names: 124266015

Gene position: 863422-864924 (Clockwise)

Preceding gene: 124266014

Following gene: 124266019

Centisome position: 21.35

GC content: 58.42

Gene sequence:

>1503_bases
ATGCTGAATCTGAGTCTGCGCCAGAAATTCCACGGCGCCATGATCGTGGTGCTGATGGTTTCCGCCATCGTTCTGTGGGG
CAACAGAATCCTCGGGAAATGCGCCCAGTTGCACTATTTTGAACGGATGCATCTCGCACAGGTCTCCGAAATCGAGAAGC
TGCTCGCCTCGATACGCAGCGACGAGCATGTGGACGACGGTCGGATGCGTCGCGAGCTCCTGCAGTACATCGATCTCGGT
CAGGGTTACGCGCGGAGCGCGGATGCGGAATTGTTGGAGGCGGAGAAACTGGTCTTCAAGATCCTCGGATTTGCTCCCAT
CATCGAGTTACCTCGCAAGGATGTCTTCGATCTCGAAGAGGTGCGCTCGACTCTGCAGTCGTCGACCGCGGAGAGCGGTG
TCAGTTCTGCCACTGCGCAGTCTCTTCGTCTCAAGATGATGCCTGTCTCGGAAAACTCGGACAGGTTTGCCGAACTTCTC
CCGACGGCCGTGAAGTTTGCCAAGGAGTTGCTGACCGCATCCGCAATCACCGGCCTGGTGCTGCTCGGAGCGACACTGGT
CTTCCTGCGTCGCGGCACGCTTCGGCCGATCAACGAGATTTTGACGGTCGCACAGACGATCGCAGGAGGAAACCTTGACG
CCGCCATTGCCGTTCGCTCGAAGGACGAGTTTGGCGAACTGATGGGTGCATTGAACAACATGAAGAACAGTCTCGCTGAC
TTGGTTCGCCAAGTCAGTGCAGGTTCCGGCCAGATCAGCAAGGCGACGAGGGAAGTCGCGTCGGGCAACTCGAATCTGTC
TGCGCGGACTGAATCCCAAGCCGCCGCTCTGCAGAAGACAGCGGCTTCAACGGTGGAACTCAAAGCCGCGGCGGAGCGGA
GTGCCGTTGGAGCGGAACGGGCAAACTCGCTGGCATTCACTGCCGCCAGCAGGGCAACGGTCGGTCGTGAAATCGGTTCC
CAGCTCGTCGAGATGATGACGCACATCAAGACTTCATCAGAGCTGATTTCGAACATCACCAGCGTGATCGATGGCATTGC
ATCCCAGATCAATATTCTTTCGCTGAATGCTGCAGTCGAAGCGGCGAGGGCAGGACAGCAAGGGCGCGGCTTCGCCGTGG
TGGCTGCCGAAGTGAGGGAGCTGGCGCAGCGTTCGGCCAGTGCTGCCAGGGAAATCAAGCAACTGATCGATGAGTCGGCT
GTGCGGGTGATGTCCGGATCCGATCTTGCTCACCGATCCGATGCCGTCATCGCGGAAGTCGAGACGGCAATCAAGGAAGT
GGCCGTTGTCATATCGGAGATTGCTGTAGAGATGCGCGATCAATGCGTCTCTGTCACGGAGATCGCTCAAGCGGTCGGGC
AAATGGACATCGTGACGCAGCAGAATGCTGCATTGGTGGAGCAGGCCGCCGTGGCTTCCGACAGCCTGCATTCGCAAGCT
GTTTCGTTGACGCAAGCCATCAGCGTTTTCAAGGTGTCCGACGTCACAGCCGCACCGGCATGA

Upstream 100 bases:

>100_bases
CATCAGCGCTATGGAGTCGAGGTCGTCGAAGGCCTCGCTATCGCTCTGATGGTGCGGGCGAGTCCGTCACAGAGCGAGTC
CGTGCAACTTAGGGCAAGTG

Downstream 100 bases:

>100_bases
ATACGCGACCGCTTCGGTCGGCTACATCGCGTAGCCCACCAGCACCACCTCGGCCGCCCGCTCGCGCAGCGGGATCAGTG
CCTGGTAGGCCGGTGAGCGG

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: MCP-III; Ribose and galactose chemoreceptor protein [H]

Number of amino acids: Translated: 500; Mature: 500

Protein sequence:

>500_residues
MLNLSLRQKFHGAMIVVLMVSAIVLWGNRILGKCAQLHYFERMHLAQVSEIEKLLASIRSDEHVDDGRMRRELLQYIDLG
QGYARSADAELLEAEKLVFKILGFAPIIELPRKDVFDLEEVRSTLQSSTAESGVSSATAQSLRLKMMPVSENSDRFAELL
PTAVKFAKELLTASAITGLVLLGATLVFLRRGTLRPINEILTVAQTIAGGNLDAAIAVRSKDEFGELMGALNNMKNSLAD
LVRQVSAGSGQISKATREVASGNSNLSARTESQAAALQKTAASTVELKAAAERSAVGAERANSLAFTAASRATVGREIGS
QLVEMMTHIKTSSELISNITSVIDGIASQINILSLNAAVEAARAGQQGRGFAVVAAEVRELAQRSASAAREIKQLIDESA
VRVMSGSDLAHRSDAVIAEVETAIKEVAVVISEIAVEMRDQCVSVTEIAQAVGQMDIVTQQNAALVEQAAVASDSLHSQA
VSLTQAISVFKVSDVTAAPA

Sequences:

>Translated_500_residues
MLNLSLRQKFHGAMIVVLMVSAIVLWGNRILGKCAQLHYFERMHLAQVSEIEKLLASIRSDEHVDDGRMRRELLQYIDLG
QGYARSADAELLEAEKLVFKILGFAPIIELPRKDVFDLEEVRSTLQSSTAESGVSSATAQSLRLKMMPVSENSDRFAELL
PTAVKFAKELLTASAITGLVLLGATLVFLRRGTLRPINEILTVAQTIAGGNLDAAIAVRSKDEFGELMGALNNMKNSLAD
LVRQVSAGSGQISKATREVASGNSNLSARTESQAAALQKTAASTVELKAAAERSAVGAERANSLAFTAASRATVGREIGS
QLVEMMTHIKTSSELISNITSVIDGIASQINILSLNAAVEAARAGQQGRGFAVVAAEVRELAQRSASAAREIKQLIDESA
VRVMSGSDLAHRSDAVIAEVETAIKEVAVVISEIAVEMRDQCVSVTEIAQAVGQMDIVTQQNAALVEQAAVASDSLHSQA
VSLTQAISVFKVSDVTAAPA
>Mature_500_residues
MLNLSLRQKFHGAMIVVLMVSAIVLWGNRILGKCAQLHYFERMHLAQVSEIEKLLASIRSDEHVDDGRMRRELLQYIDLG
QGYARSADAELLEAEKLVFKILGFAPIIELPRKDVFDLEEVRSTLQSSTAESGVSSATAQSLRLKMMPVSENSDRFAELL
PTAVKFAKELLTASAITGLVLLGATLVFLRRGTLRPINEILTVAQTIAGGNLDAAIAVRSKDEFGELMGALNNMKNSLAD
LVRQVSAGSGQISKATREVASGNSNLSARTESQAAALQKTAASTVELKAAAERSAVGAERANSLAFTAASRATVGREIGS
QLVEMMTHIKTSSELISNITSVIDGIASQINILSLNAAVEAARAGQQGRGFAVVAAEVRELAQRSASAAREIKQLIDESA
VRVMSGSDLAHRSDAVIAEVETAIKEVAVVISEIAVEMRDQCVSVTEIAQAVGQMDIVTQQNAALVEQAAVASDSLHSQA
VSLTQAISVFKVSDVTAAPA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=414, Percent_Identity=37.1980676328502, Blast_Score=229, Evalue=2e-61,
Organism=Escherichia coli, GI1788195, Length=313, Percent_Identity=46.0063897763578, Blast_Score=228, Evalue=5e-61,
Organism=Escherichia coli, GI1788194, Length=319, Percent_Identity=44.2006269592476, Blast_Score=228, Evalue=6e-61,
Organism=Escherichia coli, GI2367378, Length=353, Percent_Identity=42.4929178470255, Blast_Score=221, Evalue=1e-58,
Organism=Escherichia coli, GI1789453, Length=332, Percent_Identity=33.433734939759, Blast_Score=167, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 53191; Mature: 53191

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNLSLRQKFHGAMIVVLMVSAIVLWGNRILGKCAQLHYFERMHLAQVSEIEKLLASIRS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DEHVDDGRMRRELLQYIDLGQGYARSADAELLEAEKLVFKILGFAPIIELPRKDVFDLEE
CCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
VRSTLQSSTAESGVSSATAQSLRLKMMPVSENSDRFAELLPTAVKFAKELLTASAITGLV
HHHHHHHHHHHHCHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGATLVFLRRGTLRPINEILTVAQTIAGGNLDAAIAVRSKDEFGELMGALNNMKNSLAD
HHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHH
LVRQVSAGSGQISKATREVASGNSNLSARTESQAAALQKTAASTVELKAAAERSAVGAER
HHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANSLAFTAASRATVGREIGSQLVEMMTHIKTSSELISNITSVIDGIASQINILSLNAAVE
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHEEHHHHHH
AARAGQQGRGFAVVAAEVRELAQRSASAAREIKQLIDESAVRVMSGSDLAHRSDAVIAEV
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
ETAIKEVAVVISEIAVEMRDQCVSVTEIAQAVGQMDIVTQQNAALVEQAAVASDSLHSQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHH
VSLTQAISVFKVSDVTAAPA
HHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MLNLSLRQKFHGAMIVVLMVSAIVLWGNRILGKCAQLHYFERMHLAQVSEIEKLLASIRS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DEHVDDGRMRRELLQYIDLGQGYARSADAELLEAEKLVFKILGFAPIIELPRKDVFDLEE
CCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
VRSTLQSSTAESGVSSATAQSLRLKMMPVSENSDRFAELLPTAVKFAKELLTASAITGLV
HHHHHHHHHHHHCHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGATLVFLRRGTLRPINEILTVAQTIAGGNLDAAIAVRSKDEFGELMGALNNMKNSLAD
HHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHH
LVRQVSAGSGQISKATREVASGNSNLSARTESQAAALQKTAASTVELKAAAERSAVGAER
HHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANSLAFTAASRATVGREIGSQLVEMMTHIKTSSELISNITSVIDGIASQINILSLNAAVE
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHEEHHHHHH
AARAGQQGRGFAVVAAEVRELAQRSASAAREIKQLIDESAVRVMSGSDLAHRSDAVIAEV
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
ETAIKEVAVVISEIAVEMRDQCVSVTEIAQAVGQMDIVTQQNAALVEQAAVASDSLHSQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHH
VSLTQAISVFKVSDVTAAPA
HHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6374654; 9097039; 9278503 [H]