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The map label for this gene is add [H]

Identifier: 124266002

GI number: 124266002

Start: 847692

End: 848765

Strand: Direct

Name: add [H]

Synonym: Mpe_A0809

Alternate gene names: 124266002

Gene position: 847692-848765 (Clockwise)

Preceding gene: 124266001

Following gene: 124266003

Centisome position: 20.96

GC content: 69.83

Gene sequence:

>1074_bases
ATGAACCGACCGACCCGCGCGCTGCCCTTCGACCCGACCCGCGTCGGGCGCGAGGCGTTGCCGGCGTTGCCGGCGCTGCT
GCGCGGCATGCCGAAGGCCGAACTGCACATCCACATCGAGGGCTCGCTGGAGCCGGAGCTGATCTTCGCGCTGGCCGGCC
GCAACGGCGTCACCTTGCCCTATGCCAGCGTCGATGCGCTGCGCGCGGCCTATGCCTTCACCGACCTGCAGAGCTTCCTC
GACATCTACTACGCCGGCGCGAGCGTGCTGCTGGAGGAGGCCGACTTCTTCGACATGGCCATGGCCTACTTCCGCCGTGC
CGCCGCGGACCGCGTGGTCCATGCCGAGTTGTTCTTCGACCCGCAGACGCACACCGAGCGCGGGGTGCCGGTCGAGACGG
TGATCCGGGGCCTGGCTCGCGCCCGCGCAACGGCGCAGCAGGAACTGGGCGTGAGCAGCGAGCTGATCCTGTGCTTCCTG
CGCCACCTCAGCGAGGACGCGGCCTTCCAGACGCTGGAGCAGGCGCTGCCTTACCGCGAGCACTTCATCGGCGTCGGCCT
CGACAGCAGCGAGCGCGGGCACCCGCCGGAGAAGTTCGCGCGGGTGTTCGCGCGCTGCCGAGAGCTCGGCCTGCGTCTCG
TGGCGCATGCCGGAGAGGAGGGGCCGCCGGCCTATGTGTGGAGTGCGCTCGACGTGTTGAAGGTCGAGCGCATCGACCAC
GGCGTGCGCAGCCTCGAGGACCCGGCGCTGGTGGCGCGACTGGCCGCCGAGCGCATGCCGCTGACGGTGTGCCCGCTGTC
GAACGTGAAGCTGCGTGTGTTCGACACGATGGCGCAGCACTCGCTCGCGGCGATGCTCGACGCCGGCCTGTGCGCCACCG
TCAACTCCGACGACCCGGCCTATTTCGGCGGCTACCTGAACCAGAACTTCATCGAGACCTTCGAGGCGCTGCCGGCACTG
GGCGCCGCACAGGCCTACCGGTTGGCACGCAACAGCTTCGAGGCCAGCTTCGCGAGCGCGGCGCAGAAGCAACGGTGGTG
CGATGCGCTCGATGCGCATTTCGCGGGGGTGTGA

Upstream 100 bases:

>100_bases
TCGGGCTGGCCTGGCGGCGCAGTGGCGTGCGGCTCGCCTGGCGGGCTGGGCCGCATGCCATGCTCGGGCAACCGACAGAC
GATCGTGAAGGAGCCGAACG

Downstream 100 bases:

>100_bases
AGGAAGCCGCCTGTTGAGTGTTGGCGCGGGCGCCGCGCCGGTCCGCTGTGTTGCGTTCATGTCCTCCGTCCCGGACTCCG
TCCGGGCCTCCCCCTTTACT

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MNRPTRALPFDPTRVGREALPALPALLRGMPKAELHIHIEGSLEPELIFALAGRNGVTLPYASVDALRAAYAFTDLQSFL
DIYYAGASVLLEEADFFDMAMAYFRRAAADRVVHAELFFDPQTHTERGVPVETVIRGLARARATAQQELGVSSELILCFL
RHLSEDAAFQTLEQALPYREHFIGVGLDSSERGHPPEKFARVFARCRELGLRLVAHAGEEGPPAYVWSALDVLKVERIDH
GVRSLEDPALVARLAAERMPLTVCPLSNVKLRVFDTMAQHSLAAMLDAGLCATVNSDDPAYFGGYLNQNFIETFEALPAL
GAAQAYRLARNSFEASFASAAQKQRWCDALDAHFAGV

Sequences:

>Translated_357_residues
MNRPTRALPFDPTRVGREALPALPALLRGMPKAELHIHIEGSLEPELIFALAGRNGVTLPYASVDALRAAYAFTDLQSFL
DIYYAGASVLLEEADFFDMAMAYFRRAAADRVVHAELFFDPQTHTERGVPVETVIRGLARARATAQQELGVSSELILCFL
RHLSEDAAFQTLEQALPYREHFIGVGLDSSERGHPPEKFARVFARCRELGLRLVAHAGEEGPPAYVWSALDVLKVERIDH
GVRSLEDPALVARLAAERMPLTVCPLSNVKLRVFDTMAQHSLAAMLDAGLCATVNSDDPAYFGGYLNQNFIETFEALPAL
GAAQAYRLARNSFEASFASAAQKQRWCDALDAHFAGV
>Mature_357_residues
MNRPTRALPFDPTRVGREALPALPALLRGMPKAELHIHIEGSLEPELIFALAGRNGVTLPYASVDALRAAYAFTDLQSFL
DIYYAGASVLLEEADFFDMAMAYFRRAAADRVVHAELFFDPQTHTERGVPVETVIRGLARARATAQQELGVSSELILCFL
RHLSEDAAFQTLEQALPYREHFIGVGLDSSERGHPPEKFARVFARCRELGLRLVAHAGEEGPPAYVWSALDVLKVERIDH
GVRSLEDPALVARLAAERMPLTVCPLSNVKLRVFDTMAQHSLAAMLDAGLCATVNSDDPAYFGGYLNQNFIETFEALPAL
GAAQAYRLARNSFEASFASAAQKQRWCDALDAHFAGV

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=346, Percent_Identity=24.8554913294798, Blast_Score=109, Evalue=4e-24,
Organism=Escherichia coli, GI1787910, Length=322, Percent_Identity=29.5031055900621, Blast_Score=130, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6324188, Length=331, Percent_Identity=43.5045317220544, Blast_Score=288, Evalue=1e-78,
Organism=Drosophila melanogaster, GI24645260, Length=342, Percent_Identity=25.4385964912281, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 39242; Mature: 39242

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRPTRALPFDPTRVGREALPALPALLRGMPKAELHIHIEGSLEPELIFALAGRNGVTLP
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCC
YASVDALRAAYAFTDLQSFLDIYYAGASVLLEEADFFDMAMAYFRRAAADRVVHAELFFD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHEEEC
PQTHTERGVPVETVIRGLARARATAQQELGVSSELILCFLRHLSEDAAFQTLEQALPYRE
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHCCHHH
HFIGVGLDSSERGHPPEKFARVFARCRELGLRLVAHAGEEGPPAYVWSALDVLKVERIDH
HEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
GVRSLEDPALVARLAAERMPLTVCPLSNVKLRVFDTMAQHSLAAMLDAGLCATVNSDDPA
HHHHCCCHHHHHHHHHHCCCEEEECCCCCEEHHHHHHHHHHHHHHHHCCCEEEECCCCCC
YFGGYLNQNFIETFEALPALGAAQAYRLARNSFEASFASAAQKQRWCDALDAHFAGV
CCCHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNRPTRALPFDPTRVGREALPALPALLRGMPKAELHIHIEGSLEPELIFALAGRNGVTLP
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCC
YASVDALRAAYAFTDLQSFLDIYYAGASVLLEEADFFDMAMAYFRRAAADRVVHAELFFD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHEEEC
PQTHTERGVPVETVIRGLARARATAQQELGVSSELILCFLRHLSEDAAFQTLEQALPYRE
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHCCHHH
HFIGVGLDSSERGHPPEKFARVFARCRELGLRLVAHAGEEGPPAYVWSALDVLKVERIDH
HEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
GVRSLEDPALVARLAAERMPLTVCPLSNVKLRVFDTMAQHSLAAMLDAGLCATVNSDDPA
HHHHCCCHHHHHHHHHHCCCEEEECCCCCEEHHHHHHHHHHHHHHHHCCCEEEECCCCCC
YFGGYLNQNFIETFEALPALGAAQAYRLARNSFEASFASAAQKQRWCDALDAHFAGV
CCCHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA