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The map label for this gene is flp [H]

Identifier: 124265952

GI number: 124265952

Start: 788366

End: 789862

Strand: Direct

Name: flp [H]

Synonym: Mpe_A0759

Alternate gene names: 124265952

Gene position: 788366-789862 (Clockwise)

Preceding gene: 124265951

Following gene: 124265956

Centisome position: 19.49

GC content: 69.21

Gene sequence:

>1497_bases
ATGTTCGACACAGATCAGGCTGCGGGCGCAGTGACCAGAGGCGCCGCGCGGCCCGCGTTGCTGCTGGCAGCAGCTGTGCT
GGCCTTCTTCACATCGGCCGCGCAGCCGCAGCCGCAGACTTCAGCCGCGTCGACCTTCGAGACAGACACTGAGCTGCAGG
CCGCGACACGGCTCTTCTCCGCTTGGCTGGAAGGCCACATGGCCCAGCGCGGCACGCCGGGTGTCATGGTCGGCGTCGTG
CATGACCAGCAGCTGGTCTGGCACAAAGGCTTCGGCTTTGCCGATGTCGCGTCTCAGCGGCCCATGACCGCGCAGACCCG
CTTCCGCATGGCCTCGCACTCCAAGATGCTCACCGCCATCGCCGTCATGCAACTGCGTGAAGAGGGCCGGCTGCGGCTGG
ACGACCCGGTGGCCCAGCACCTGCCGTGGTTCAAGCTGAAGCCGGCGGGCGACGACGACGGGCCTGTCACGATCGAACAG
CTGCTGTCGCACAGCTCGGGCTTGCCGCGCGAAGCCAGCGACCACTGGACCTCGCTGCAGTTCCCCAGCCGCAGCGAGTT
GCAGGCGCTGATGGCGCAGAGACAGTCGACCTTCGCGCCGCAGGTGCGCTGGAAGTACTCGAATCTGGCCTACGGCGTGG
CCGGCCAGGTGGTGGAGCAGCTCAGCGGACAACCGTTCGCCAGCTACGCGCAGGCCCACATCCTGGGCCCGCTGGGCATG
CAGGACTCCAGCTACGACCAGGACGTGCCGGGCCTGGCCACGCCCTACGGCCGGCGCCTGCCGGACGGCACGCGTGTGAG
CTTCCCCTTCGTCGATGCGCGTGGCCTGGCTGCTGCCACCGGCCTGACCTCGACGCTCGACGACATGGTGAAGTTCGTCT
CGGCCCAGTTCCGGCGCGGCCCGCGTGGCGGCACGCAGATCATCAGCAGCGGCTCCCTCCGTGAGATGCACCGCGTGCGG
TCCGTGGACGAGAATTGGTCCGTTGGCACCGGCCTGGGCTTTCTGACCACGCGCATCAACAACAAGAGCTACGTCGGCCA
CGGCGGCGGCTACCCCGGCTACACGACGCAGACGCTGTTCCACCTTGGCGACAAGCTCGGCGTCATCGTGCTCACCAACA
GCGCCGATTCGGGCGTGAACGACATCGCCCGCCAGGCGATTGCGGCCTTTGGCCCGCCGGTGGCGAAAGTCGCCGCCGCA
GGCGCGACCACCCCCGCCTGGGACCCGGCCTGGGCGCGTTTCCAGGGCATGTACCGCAGCCGCGGCGGCGACACCTTTGT
GGTCATGCTGAACAAGCGGCTGGTGCTGCTGGGCGCGTCGGCGGCGGGCATCGATGCCGCCACCCGGCTGGAGCCGCTCG
GCAACGGCCACTTCCGGCTCGACAGCGCCACAGGGGGGCCGCCGGTCGGCGAGGTGGTGTACTTTCAGGAGGGCAGCGGC
AAGCCCATGCGCATGGTCGTGGGCGACAACACGTCGGAGCGCATCGCGGCGCCTTAG

Upstream 100 bases:

>100_bases
CGACGACTCGTACGGGGCTCGTGCGCTTGCGGCAGCCGATCGGAAACGCGTCGTATACGCTCCGTGCCTGTCGCATGCCG
GGCATGCATCTGGGGACCAC

Downstream 100 bases:

>100_bases
TCCGGCTGTTAACTGAGCGGCGCCGGCATCCGGCAGGTGACTTCCGAAGGATGAAATGCCGGTCAGCCGGCTCAGCCGGC
TCAGCCGCCGTACGGCTGCC

Product: putative beta-lactamase class C penicillin binding protein

Products: NA

Alternate protein names: FmtA-like protein [H]

Number of amino acids: Translated: 498; Mature: 498

Protein sequence:

>498_residues
MFDTDQAAGAVTRGAARPALLLAAAVLAFFTSAAQPQPQTSAASTFETDTELQAATRLFSAWLEGHMAQRGTPGVMVGVV
HDQQLVWHKGFGFADVASQRPMTAQTRFRMASHSKMLTAIAVMQLREEGRLRLDDPVAQHLPWFKLKPAGDDDGPVTIEQ
LLSHSSGLPREASDHWTSLQFPSRSELQALMAQRQSTFAPQVRWKYSNLAYGVAGQVVEQLSGQPFASYAQAHILGPLGM
QDSSYDQDVPGLATPYGRRLPDGTRVSFPFVDARGLAAATGLTSTLDDMVKFVSAQFRRGPRGGTQIISSGSLREMHRVR
SVDENWSVGTGLGFLTTRINNKSYVGHGGGYPGYTTQTLFHLGDKLGVIVLTNSADSGVNDIARQAIAAFGPPVAKVAAA
GATTPAWDPAWARFQGMYRSRGGDTFVVMLNKRLVLLGASAAGIDAATRLEPLGNGHFRLDSATGGPPVGEVVYFQEGSG
KPMRMVVGDNTSERIAAP

Sequences:

>Translated_498_residues
MFDTDQAAGAVTRGAARPALLLAAAVLAFFTSAAQPQPQTSAASTFETDTELQAATRLFSAWLEGHMAQRGTPGVMVGVV
HDQQLVWHKGFGFADVASQRPMTAQTRFRMASHSKMLTAIAVMQLREEGRLRLDDPVAQHLPWFKLKPAGDDDGPVTIEQ
LLSHSSGLPREASDHWTSLQFPSRSELQALMAQRQSTFAPQVRWKYSNLAYGVAGQVVEQLSGQPFASYAQAHILGPLGM
QDSSYDQDVPGLATPYGRRLPDGTRVSFPFVDARGLAAATGLTSTLDDMVKFVSAQFRRGPRGGTQIISSGSLREMHRVR
SVDENWSVGTGLGFLTTRINNKSYVGHGGGYPGYTTQTLFHLGDKLGVIVLTNSADSGVNDIARQAIAAFGPPVAKVAAA
GATTPAWDPAWARFQGMYRSRGGDTFVVMLNKRLVLLGASAAGIDAATRLEPLGNGHFRLDSATGGPPVGEVVYFQEGSG
KPMRMVVGDNTSERIAAP
>Mature_498_residues
MFDTDQAAGAVTRGAARPALLLAAAVLAFFTSAAQPQPQTSAASTFETDTELQAATRLFSAWLEGHMAQRGTPGVMVGVV
HDQQLVWHKGFGFADVASQRPMTAQTRFRMASHSKMLTAIAVMQLREEGRLRLDDPVAQHLPWFKLKPAGDDDGPVTIEQ
LLSHSSGLPREASDHWTSLQFPSRSELQALMAQRQSTFAPQVRWKYSNLAYGVAGQVVEQLSGQPFASYAQAHILGPLGM
QDSSYDQDVPGLATPYGRRLPDGTRVSFPFVDARGLAAATGLTSTLDDMVKFVSAQFRRGPRGGTQIISSGSLREMHRVR
SVDENWSVGTGLGFLTTRINNKSYVGHGGGYPGYTTQTLFHLGDKLGVIVLTNSADSGVNDIARQAIAAFGPPVAKVAAA
GATTPAWDPAWARFQGMYRSRGGDTFVVMLNKRLVLLGASAAGIDAATRLEPLGNGHFRLDSATGGPPVGEVVYFQEGSG
KPMRMVVGDNTSERIAAP

Specific function: Its precise function is unknown. Has no penicillin- binding activity and is not involved in methicillin resistance [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI26051231, Length=148, Percent_Identity=34.4594594594595, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI26051233, Length=142, Percent_Identity=35.2112676056338, Blast_Score=81, Evalue=3e-15,
Organism=Escherichia coli, GI87082101, Length=390, Percent_Identity=24.8717948717949, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1786574, Length=282, Percent_Identity=26.241134751773, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790593, Length=263, Percent_Identity=25.8555133079848, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115533026, Length=399, Percent_Identity=26.8170426065163, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17550934, Length=189, Percent_Identity=25.9259259259259, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17565630, Length=327, Percent_Identity=25.0764525993884, Blast_Score=80, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: NA

Molecular weight: Translated: 53315; Mature: 53315

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDTDQAAGAVTRGAARPALLLAAAVLAFFTSAAQPQPQTSAASTFETDTELQAATRLFS
CCCCCHHCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHH
AWLEGHMAQRGTPGVMVGVVHDQQLVWHKGFGFADVASQRPMTAQTRFRMASHSKMLTAI
HHHHHHHHCCCCCCEEEEEEECCEEEEECCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHH
AVMQLREEGRLRLDDPVAQHLPWFKLKPAGDDDGPVTIEQLLSHSSGLPREASDHWTSLQ
HHHHHHHCCCCEECCHHHHHCCCEEEECCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCC
FPSRSELQALMAQRQSTFAPQVRWKYSNLAYGVAGQVVEQLSGQPFASYAQAHILGPLGM
CCCHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCC
QDSSYDQDVPGLATPYGRRLPDGTRVSFPFVDARGLAAATGLTSTLDDMVKFVSAQFRRG
CCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
PRGGTQIISSGSLREMHRVRSVDENWSVGTGLGFLTTRINNKSYVGHGGGYPGYTTQTLF
CCCCHHHCCCCCHHHHHHHHCCCCCCCCCCCCEEEEEEECCCEEECCCCCCCCHHHHHHH
HLGDKLGVIVLTNSADSGVNDIARQAIAAFGPPVAKVAAAGATTPAWDPAWARFQGMYRS
HCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCHHHHHHHHHHHC
RGGDTFVVMLNKRLVLLGASAAGIDAATRLEPLGNGHFRLDSATGGPPVGEVVYFQEGSG
CCCCEEEEEECCEEEEEECCCCCCCHHHHHCCCCCCCEEEECCCCCCCCCEEEEEECCCC
KPMRMVVGDNTSERIAAP
CEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MFDTDQAAGAVTRGAARPALLLAAAVLAFFTSAAQPQPQTSAASTFETDTELQAATRLFS
CCCCCHHCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHH
AWLEGHMAQRGTPGVMVGVVHDQQLVWHKGFGFADVASQRPMTAQTRFRMASHSKMLTAI
HHHHHHHHCCCCCCEEEEEEECCEEEEECCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHH
AVMQLREEGRLRLDDPVAQHLPWFKLKPAGDDDGPVTIEQLLSHSSGLPREASDHWTSLQ
HHHHHHHCCCCEECCHHHHHCCCEEEECCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCC
FPSRSELQALMAQRQSTFAPQVRWKYSNLAYGVAGQVVEQLSGQPFASYAQAHILGPLGM
CCCHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCC
QDSSYDQDVPGLATPYGRRLPDGTRVSFPFVDARGLAAATGLTSTLDDMVKFVSAQFRRG
CCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
PRGGTQIISSGSLREMHRVRSVDENWSVGTGLGFLTTRINNKSYVGHGGGYPGYTTQTLF
CCCCHHHCCCCCHHHHHHHHCCCCCCCCCCCCEEEEEEECCCEEECCCCCCCCHHHHHHH
HLGDKLGVIVLTNSADSGVNDIARQAIAAFGPPVAKVAAAGATTPAWDPAWARFQGMYRS
HCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCHHHHHHHHHHHC
RGGDTFVVMLNKRLVLLGASAAGIDAATRLEPLGNGHFRLDSATGGPPVGEVVYFQEGSG
CCCCEEEEEECCEEEEEECCCCCCCHHHHHCCCCCCCEEEECCCCCCCCCEEEEEECCCC
KPMRMVVGDNTSERIAAP
CEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA