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The map label for this gene is int [H]

Identifier: 124265889

GI number: 124265889

Start: 725394

End: 726410

Strand: Direct

Name: int [H]

Synonym: Mpe_A0696

Alternate gene names: 124265889

Gene position: 725394-726410 (Clockwise)

Preceding gene: 124265884

Following gene: 124265890

Centisome position: 17.94

GC content: 70.3

Gene sequence:

>1017_bases
ATGCCTGTTCCCGATCCGGAGCCCGCTGAATCGACGACGACGACGCCACTCGCGCCGCCGCCCCGCCTGCTCGACCAGCT
CCGCGAGCACATTCGAGTCAAGCACTACGCCTTGCGCACCGAGCGCACCTACGTGGAATGGGTGCGCCGCTACATCCTGT
TTCACGGCAAGCGCCATCCGCGCGACATGGGGGCGCTGGAGATCGAAGCGTTTCTCAGCCACCTGGCGCTGGAGCGCGGC
GTGGCCTCGGCCACGCAGAACCAGGCCAAGGCGGCCTTGCTGTTCCTCTACAAGGAGGTGCTGCGTGCGGTCGATCTGCC
CTGGCTCACCGAGGTGGTGGCTGCCAAGACCTCGCGCCGTCTGCCGGTGGTGCTCACGCAGCGCGAGGCGCGCGAACTGC
TGATGCAGCTCCACGGCGCGCACTGGCTCGCCGCGTCGCTGCTCTACGGCAGTGGCCTGCGGCTGCTGGAATGCCTGCGC
CTGCGCGTCAAGGACGTGGAGTTCGAGCGTCGCGAACTCGTCGTGCGCCAGGGCAAGGGCAGCAAGGACCGCGTGACGGT
GTTGCCAGAGAATCTGCTGCTGCCTCTGCGCAACCAGCTCGCGCAGGCCCGGGCGCTGCACGAGCGCGACCTGGCCGCCG
GCCGTGGCGCGGTCTGGCTGCCCGACGCGCTGGCGGTCAAGTTCCCGCGGGCGGCTCGGGCCTGGGGCTGGCAGTGGGTG
TTTCCGTCACGGGTGCTGTCCGTCGACCCACGCAGCGGCGTGGAGCGCCGGCACCACCTGGCCGAGCAGGGCCTGCAGCG
CGCGGTGTCGCTGGCGGCCCGCCGTGCCGGGATCGACAAGCCGTGCTCGCCGCATGTGCTGCGCCATTCCTTCGCCACCC
ACATGCTGCAGGCCGGTTACGACATCCGCACGGTGCAGGAGCTGCTGGGCCATGCCGACGTCAAGACCACCATGATCTAC
ACGCACGTGCTCAACCGCGGCGGCCGCGGGGTGCTGAGCCCGCTCGACGCGCTCTGA

Upstream 100 bases:

>100_bases
ACGCAACCCCTGCGTGGGGTGTCACGGCGTGCACGACGCCCTGCAGAGGGCCCCTTTCTGGCCGATGGGCGCGGGCGTTT
AGGCGGCCTAAATTTCCTGG

Downstream 100 bases:

>100_bases
GCCGGTGTCTCTACGCCACCTTGCGTATTCCGCCGCCCGGGGGTTCTGCCTAACCTGCAGCGGTCCGTGAACCCAACCGA
TCCCCCGAGGAGGAAACACC

Product: phage integrase

Products: NA

Alternate protein names: E2 protein [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MPVPDPEPAESTTTTPLAPPPRLLDQLREHIRVKHYALRTERTYVEWVRRYILFHGKRHPRDMGALEIEAFLSHLALERG
VASATQNQAKAALLFLYKEVLRAVDLPWLTEVVAAKTSRRLPVVLTQREARELLMQLHGAHWLAASLLYGSGLRLLECLR
LRVKDVEFERRELVVRQGKGSKDRVTVLPENLLLPLRNQLAQARALHERDLAAGRGAVWLPDALAVKFPRAARAWGWQWV
FPSRVLSVDPRSGVERRHHLAEQGLQRAVSLAARRAGIDKPCSPHVLRHSFATHMLQAGYDIRTVQELLGHADVKTTMIY
THVLNRGGRGVLSPLDAL

Sequences:

>Translated_338_residues
MPVPDPEPAESTTTTPLAPPPRLLDQLREHIRVKHYALRTERTYVEWVRRYILFHGKRHPRDMGALEIEAFLSHLALERG
VASATQNQAKAALLFLYKEVLRAVDLPWLTEVVAAKTSRRLPVVLTQREARELLMQLHGAHWLAASLLYGSGLRLLECLR
LRVKDVEFERRELVVRQGKGSKDRVTVLPENLLLPLRNQLAQARALHERDLAAGRGAVWLPDALAVKFPRAARAWGWQWV
FPSRVLSVDPRSGVERRHHLAEQGLQRAVSLAARRAGIDKPCSPHVLRHSFATHMLQAGYDIRTVQELLGHADVKTTMIY
THVLNRGGRGVLSPLDAL
>Mature_337_residues
PVPDPEPAESTTTTPLAPPPRLLDQLREHIRVKHYALRTERTYVEWVRRYILFHGKRHPRDMGALEIEAFLSHLALERGV
ASATQNQAKAALLFLYKEVLRAVDLPWLTEVVAAKTSRRLPVVLTQREARELLMQLHGAHWLAASLLYGSGLRLLECLRL
RVKDVEFERRELVVRQGKGSKDRVTVLPENLLLPLRNQLAQARALHERDLAAGRGAVWLPDALAVKFPRAARAWGWQWVF
PSRVLSVDPRSGVERRHHLAEQGLQRAVSLAARRAGIDKPCSPHVLRHSFATHMLQAGYDIRTVQELLGHADVKTTMIYT
HVLNRGGRGVLSPLDAL

Specific function: Putative integrase believed to be involved in the insertion of antibiotic resistance genes into plasmids and transposons [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=239, Percent_Identity=32.2175732217573, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1790244, Length=180, Percent_Identity=35.5555555555556, Blast_Score=81, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR011946
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 38247; Mature: 38116

Theoretical pI: Translated: 10.89; Mature: 10.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVPDPEPAESTTTTPLAPPPRLLDQLREHIRVKHYALRTERTYVEWVRRYILFHGKRHP
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RDMGALEIEAFLSHLALERGVASATQNQAKAALLFLYKEVLRAVDLPWLTEVVAAKTSRR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
LPVVLTQREARELLMQLHGAHWLAASLLYGSGLRLLECLRLRVKDVEFERRELVVRQGKG
CCEEECHHHHHHHHHHHHCHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHCCCC
SKDRVTVLPENLLLPLRNQLAQARALHERDLAAGRGAVWLPDALAVKFPRAARAWGWQWV
CCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHCCCCHHHHCCCEEE
FPSRVLSVDPRSGVERRHHLAEQGLQRAVSLAARRAGIDKPCSPHVLRHSFATHMLQAGY
CCCHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCC
DIRTVQELLGHADVKTTMIYTHVLNRGGRGVLSPLDAL
CHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHCCC
>Mature Secondary Structure 
PVPDPEPAESTTTTPLAPPPRLLDQLREHIRVKHYALRTERTYVEWVRRYILFHGKRHP
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RDMGALEIEAFLSHLALERGVASATQNQAKAALLFLYKEVLRAVDLPWLTEVVAAKTSRR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
LPVVLTQREARELLMQLHGAHWLAASLLYGSGLRLLECLRLRVKDVEFERRELVVRQGKG
CCEEECHHHHHHHHHHHHCHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHCCCC
SKDRVTVLPENLLLPLRNQLAQARALHERDLAAGRGAVWLPDALAVKFPRAARAWGWQWV
CCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHCCCCHHHHCCCEEE
FPSRVLSVDPRSGVERRHHLAEQGLQRAVSLAARRAGIDKPCSPHVLRHSFATHMLQAGY
CCCHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCC
DIRTVQELLGHADVKTTMIYTHVLNRGGRGVLSPLDAL
CHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2821509; 2823258; 3054482; 8195081; 2188588 [H]