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The map label for this gene is tagO [H]

Identifier: 124265823

GI number: 124265823

Start: 664878

End: 665972

Strand: Direct

Name: tagO [H]

Synonym: Mpe_A0630

Alternate gene names: 124265823

Gene position: 664878-665972 (Clockwise)

Preceding gene: 124265810

Following gene: 124265824

Centisome position: 16.44

GC content: 67.31

Gene sequence:

>1095_bases
ATGCTTCTGTTTCTCTGCGCGTTCGCCGCGTCGGCCATCCTGACCTTGCTGGTGGTCCGCTCGAACCGCACTCATGCCCG
GTTCTCCGCCGATCCGGACCAGGGCGGCCCGCAGAAATTCCATGCACGCTCCGTGCCGCGGGTGGGTGGGATCGGCATCG
TCGGCGGGCTGCTGTTCACGGCCACGCTGCTGTGGTGGATGCGCGGCGGCGAGCCTGCGCACTATGCCGTCTGGTTGCTG
CTGTGCGGCCTGCCGGCCTTTGCCGCAGGCCTGGCCGAAGACGTGACCAAGCGTGTCTCGGCCACCTGGCGCCTGCTGGC
GACGGCGGCCGCTGCGCTGCTGGGGGTGTTGTTGCTCGGCGGGACCATCACGCGCACCGACCTTTGGGGGCTGGACTGGA
TCGCATCGTTCGCGCTCGGTGCGGCCTTTCTCGCGATCTTCACCGTGACGGGCATCGCCAATGCCATCAACATCATCGAC
GGCTTCAACGGGCTGGCATCGATGTGCGTGATGATGATGCTGCTGGCCATCACCTATGTGGCCAACCAGGTGGGCGACAG
CACCATCGCGCTGCTGGCGCTGGCCGGCGCCGGGGCCGTGCTGGGGTTCTTCGTCTGGAACTTCCCGGCCGGACTGATCT
TCCTGGGCGACGGCGGCGCCTATTTCCTGGGCTTCTACCTGTCCGAGCTCAGCATCCTGCTGCTGCACCGCAACCCCGAG
GTGTCGCCGCTGTTCCCGCTGCTGATGGCCATCTACCCGGTGTTCGAGACCCTGTTCTCGATGTACCGGCGCCGGGTGGT
CCGCGGGCGCGGCGTGGGCATTCCCGACGGCGTCCACCTGCACAGCCTGATTTACCGGCGCCTGCTGCGCTGGGCCGTCG
GCAGCCGCGACGCGGCCGCGCTGACGCGGCGCAATTCCATGACCGCGCCCTACCTGTGGCTGCTGTGCATGCTGGCGGTG
GCGCCCAGCGTGCTGTTCTGGGACAACTCTCGGGTCCTGGGCATCTTCATCCTGTTGTTCGGACTGTCGTACACCCTGCT
GTACGGGATGATCGTGCGCTTCAAGGCCCCCCGCTGGCTGGTTCTGAGACGCTGA

Upstream 100 bases:

>100_bases
GTGATGTGATGCATGGTGGCAAAAGTGAGGGGCAAGCGCAGTCCCACTATAGCGGCGCGCCTCAAGGGGTCCGGATGTGC
GCGCTCGGTAAACTGCCCCG

Downstream 100 bases:

>100_bases
AACCCGGCTGGCCGATAATGGCGGCCAATGCAAGACGATCTCACAATGGCGTCACCGGCCCTGCCGGCCGAGGCGCCGCC
CGCCCGTTTCGACACCCTCG

Product: putative undecaprenyl phosphate N-acetylglucosaminyltransferase

Products: UMP; Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

Alternate protein names: UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; Undecaprenyl-Phosphate GlcNAc-1-phosphate transferase [H]

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MLLFLCAFAASAILTLLVVRSNRTHARFSADPDQGGPQKFHARSVPRVGGIGIVGGLLFTATLLWWMRGGEPAHYAVWLL
LCGLPAFAAGLAEDVTKRVSATWRLLATAAAALLGVLLLGGTITRTDLWGLDWIASFALGAAFLAIFTVTGIANAINIID
GFNGLASMCVMMMLLAITYVANQVGDSTIALLALAGAGAVLGFFVWNFPAGLIFLGDGGAYFLGFYLSELSILLLHRNPE
VSPLFPLLMAIYPVFETLFSMYRRRVVRGRGVGIPDGVHLHSLIYRRLLRWAVGSRDAAALTRRNSMTAPYLWLLCMLAV
APSVLFWDNSRVLGIFILLFGLSYTLLYGMIVRFKAPRWLVLRR

Sequences:

>Translated_364_residues
MLLFLCAFAASAILTLLVVRSNRTHARFSADPDQGGPQKFHARSVPRVGGIGIVGGLLFTATLLWWMRGGEPAHYAVWLL
LCGLPAFAAGLAEDVTKRVSATWRLLATAAAALLGVLLLGGTITRTDLWGLDWIASFALGAAFLAIFTVTGIANAINIID
GFNGLASMCVMMMLLAITYVANQVGDSTIALLALAGAGAVLGFFVWNFPAGLIFLGDGGAYFLGFYLSELSILLLHRNPE
VSPLFPLLMAIYPVFETLFSMYRRRVVRGRGVGIPDGVHLHSLIYRRLLRWAVGSRDAAALTRRNSMTAPYLWLLCMLAV
APSVLFWDNSRVLGIFILLFGLSYTLLYGMIVRFKAPRWLVLRR
>Mature_364_residues
MLLFLCAFAASAILTLLVVRSNRTHARFSADPDQGGPQKFHARSVPRVGGIGIVGGLLFTATLLWWMRGGEPAHYAVWLL
LCGLPAFAAGLAEDVTKRVSATWRLLATAAAALLGVLLLGGTITRTDLWGLDWIASFALGAAFLAIFTVTGIANAINIID
GFNGLASMCVMMMLLAITYVANQVGDSTIALLALAGAGAVLGFFVWNFPAGLIFLGDGGAYFLGFYLSELSILLLHRNPE
VSPLFPLLMAIYPVFETLFSMYRRRVVRGRGVGIPDGVHLHSLIYRRLLRWAVGSRDAAALTRRNSMTAPYLWLLCMLAV
APSVLFWDNSRVLGIFILLFGLSYTLLYGMIVRFKAPRWLVLRR

Specific function: Catalyzes the formation of undecaprenyl-PP-N- acetylglucosamine. Involved in the synthesis of anionic cell-wall polymers as it mediates the initiation of the linkage unit formation that appears to be common to the two types of teichoic acids attached to t

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family [H]

Homologues:

Organism=Escherichia coli, GI1790218, Length=266, Percent_Identity=26.6917293233083, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: 2.7.8.- [C]

Molecular weight: Translated: 39670; Mature: 39670

Theoretical pI: Translated: 10.45; Mature: 10.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLFLCAFAASAILTLLVVRSNRTHARFSADPDQGGPQKFHARSVPRVGGIGIVGGLLFT
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHH
ATLLWWMRGGEPAHYAVWLLLCGLPAFAAGLAEDVTKRVSATWRLLATAAAALLGVLLLG
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GTITRTDLWGLDWIASFALGAAFLAIFTVTGIANAINIIDGFNGLASMCVMMMLLAITYV
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
ANQVGDSTIALLALAGAGAVLGFFVWNFPAGLIFLGDGGAYFLGFYLSELSILLLHRNPE
HHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHEEEEECCCC
VSPLFPLLMAIYPVFETLFSMYRRRVVRGRGVGIPDGVHLHSLIYRRLLRWAVGSRDAAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHH
LTRRNSMTAPYLWLLCMLAVAPSVLFWDNSRVLGIFILLFGLSYTLLYGMIVRFKAPRWL
HHHCCCCCHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
VLRR
EECC
>Mature Secondary Structure
MLLFLCAFAASAILTLLVVRSNRTHARFSADPDQGGPQKFHARSVPRVGGIGIVGGLLFT
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHH
ATLLWWMRGGEPAHYAVWLLLCGLPAFAAGLAEDVTKRVSATWRLLATAAAALLGVLLLG
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GTITRTDLWGLDWIASFALGAAFLAIFTVTGIANAINIIDGFNGLASMCVMMMLLAITYV
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
ANQVGDSTIALLALAGAGAVLGFFVWNFPAGLIFLGDGGAYFLGFYLSELSILLLHRNPE
HHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHEEEEECCCC
VSPLFPLLMAIYPVFETLFSMYRRRVVRGRGVGIPDGVHLHSLIYRRLLRWAVGSRDAAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHH
LTRRNSMTAPYLWLLCMLAVAPSVLFWDNSRVLGIFILLFGLSYTLLYGMIVRFKAPRWL
HHHCCCCCHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
VLRR
EECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-N-Acetyl-D-Glucosamine; Undecaprenyl Phosphate [C]

Specific reaction: UDP-N-Acetyl-D-Glucosamine + Undecaprenyl Phosphate = UMP + Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12101296; 9384377 [H]