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The map label for this gene is pilC [H]

Identifier: 124265701

GI number: 124265701

Start: 546037

End: 547263

Strand: Reverse

Name: pilC [H]

Synonym: Mpe_A0508

Alternate gene names: 124265701

Gene position: 547263-546037 (Counterclockwise)

Preceding gene: 124265702

Following gene: 124265700

Centisome position: 13.53

GC content: 63.08

Gene sequence:

>1227_bases
ATGGCCACAGCAGCAACGGCTTCGGCGCGAGACATCAAGGAATTCGTCTTCGAGTGGGAAGGCAAGGACAAGAACGGCAA
GGTCGTGCGCGGCGAGATGCGAGCCGGCGGCGAGTCGGTCGTCAGCGCGTCCCTGCGCCGCCAGGGCATCCTCGTCAACA
AGGTGAAGAAGCGCCGCATGAGCGGCGGCAAGTCCATCAAGCCGAAGGATATTGCGATCTTCACGCGCCAGATCGCGACG
ATGATGCGCGCCGGCGTTCCCTTGCTGCAGTCCTTCGACATCGTCGCGCGGGGCAGCACCAACCCTCGCGTGACCAAGCT
GCTGACCGACATCCGCTCCGACATCGAGACCGGCACCAGCCTGTCGTCGGCCTTCCGCAAGCACCCGCTGTACTTCGACG
CGCTCTACTGCAACCTCGTCGAGGCCGGTGAAGCCGCAGGTATCCTGGAAACACTGCTCGAGCGGCTGGCGACCTACCAG
GAGAAGACGCTCGAGATCAAGCGCAAGATCAAGTCGGCGCTGATCTACCCGGTGGCCGTGCTGGTGGTGGCCTTCGTGGT
CGTCGCGGTCATCATGATCTTCGTGATCCCGGCCTTCAAGGAAGTCTTCACGTCCTTCGGAGCCGACCTCCCGGCCCCGA
CGCTGTTCGTGATGTCCATGTCCGAGATCTTCGTCAGCTACTGGTGGCTGATCTTCGGCGTCATCATCGGCGGCACCTAC
TTCTTCTTCGAGTCGTGGAAGCGATCCGAGAAGATGCAGAAGACCATGGACAGGCTGCTGTTGAAGCTGCCGGTGTTCGG
TGATCTGATCTTCAAGTCGGCCGTCGCTCGCTGGACGCGCACGCTCGCCACGATGTTCGCGGCCGGCGTACCGCTGGTCG
AGGCGCTCGACTCGGTCGGTGGCGCCTCTGGCAATGCCGTGTTCGCCGAAGCGACGGAGCAGATCCAGAAGGACGTCTCC
ACCGGCACGGCACTGACCACCTCGATGCAGGCGACCGGCATCTTCCCCGTGATGGTGCTGCAGATGGCTGCCATCGGTGA
GGAATCGGGCGCCCTCGATCACATGCTGTCCAAGGCTGCCGAGTTCTACGAGGCCGAGGTCGATGAGGCCGTCAAGGGCC
TGTCGAGCCTGCTCGAGCCGATCATCATCGTCGTGCTGGGCACCATCATCGGCGGCATCGTGGTCTCGATGTACCTGCCG
ATCTTCAAGCTCGGCCAGGTGGTCTGA

Upstream 100 bases:

>100_bases
GGGTCTGGTCAAGGTGCGAGCGGGTGTGACCACCCTGGAAGAAGTCATCTCGGTCACCAACGAGTAAGCCCATTAGGCGG
CGGGGAGAGTCGGAGACACC

Downstream 100 bases:

>100_bases
GCACGCCCGGAGGCATGTCGTCCGACCTGCAGGGCGTGCTGCTGTCGCCCTGGGCTCTGGGGCTGCTCGGGCTGTGCATC
GGCAGCTTTCTCAACGTCGT

Product: pilus tip-associated protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MATAATASARDIKEFVFEWEGKDKNGKVVRGEMRAGGESVVSASLRRQGILVNKVKKRRMSGGKSIKPKDIAIFTRQIAT
MMRAGVPLLQSFDIVARGSTNPRVTKLLTDIRSDIETGTSLSSAFRKHPLYFDALYCNLVEAGEAAGILETLLERLATYQ
EKTLEIKRKIKSALIYPVAVLVVAFVVVAVIMIFVIPAFKEVFTSFGADLPAPTLFVMSMSEIFVSYWWLIFGVIIGGTY
FFFESWKRSEKMQKTMDRLLLKLPVFGDLIFKSAVARWTRTLATMFAAGVPLVEALDSVGGASGNAVFAEATEQIQKDVS
TGTALTTSMQATGIFPVMVLQMAAIGEESGALDHMLSKAAEFYEAEVDEAVKGLSSLLEPIIIVVLGTIIGGIVVSMYLP
IFKLGQVV

Sequences:

>Translated_408_residues
MATAATASARDIKEFVFEWEGKDKNGKVVRGEMRAGGESVVSASLRRQGILVNKVKKRRMSGGKSIKPKDIAIFTRQIAT
MMRAGVPLLQSFDIVARGSTNPRVTKLLTDIRSDIETGTSLSSAFRKHPLYFDALYCNLVEAGEAAGILETLLERLATYQ
EKTLEIKRKIKSALIYPVAVLVVAFVVVAVIMIFVIPAFKEVFTSFGADLPAPTLFVMSMSEIFVSYWWLIFGVIIGGTY
FFFESWKRSEKMQKTMDRLLLKLPVFGDLIFKSAVARWTRTLATMFAAGVPLVEALDSVGGASGNAVFAEATEQIQKDVS
TGTALTTSMQATGIFPVMVLQMAAIGEESGALDHMLSKAAEFYEAEVDEAVKGLSSLLEPIIIVVLGTIIGGIVVSMYLP
IFKLGQVV
>Mature_407_residues
ATAATASARDIKEFVFEWEGKDKNGKVVRGEMRAGGESVVSASLRRQGILVNKVKKRRMSGGKSIKPKDIAIFTRQIATM
MRAGVPLLQSFDIVARGSTNPRVTKLLTDIRSDIETGTSLSSAFRKHPLYFDALYCNLVEAGEAAGILETLLERLATYQE
KTLEIKRKIKSALIYPVAVLVVAFVVVAVIMIFVIPAFKEVFTSFGADLPAPTLFVMSMSEIFVSYWWLIFGVIIGGTYF
FFESWKRSEKMQKTMDRLLLKLPVFGDLIFKSAVARWTRTLATMFAAGVPLVEALDSVGGASGNAVFAEATEQIQKDVST
GTALTTSMQATGIFPVMVLQMAAIGEESGALDHMLSKAAEFYEAEVDEAVKGLSSLLEPIIIVVLGTIIGGIVVSMYLPI
FKLGQVV

Specific function: Involved in the translocation of the type IV pilin (pilA) [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=400, Percent_Identity=29.5, Blast_Score=201, Evalue=7e-53,
Organism=Escherichia coli, GI1786295, Length=392, Percent_Identity=28.0612244897959, Blast_Score=164, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 44498; Mature: 44367

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATAATASARDIKEFVFEWEGKDKNGKVVRGEMRAGGESVVSASLRRQGILVNKVKKRRM
CCCCCCCHHHHHHHHHHHCCCCCCCCCEEECHHHCCHHHHHHHHHHHCCHHHHHHHHHHH
SGGKSIKPKDIAIFTRQIATMMRAGVPLLQSFDIVARGSTNPRVTKLLTDIRSDIETGTS
CCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCHHCCCCCCHHHHHHHHHHHHHHHCCCH
LSSAFRKHPLYFDALYCNLVEAGEAAGILETLLERLATYQEKTLEIKRKIKSALIYPVAV
HHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVVAFVVVAVIMIFVIPAFKEVFTSFGADLPAPTLFVMSMSEIFVSYWWLIFGVIIGGTY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFFESWKRSEKMQKTMDRLLLKLPVFGDLIFKSAVARWTRTLATMFAAGVPLVEALDSVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHC
GASGNAVFAEATEQIQKDVSTGTALTTSMQATGIFPVMVLQMAAIGEESGALDHMLSKAA
CCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHHH
EFYEAEVDEAVKGLSSLLEPIIIVVLGTIIGGIVVSMYLPIFKLGQVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ATAATASARDIKEFVFEWEGKDKNGKVVRGEMRAGGESVVSASLRRQGILVNKVKKRRM
CCCCCCHHHHHHHHHHHCCCCCCCCCEEECHHHCCHHHHHHHHHHHCCHHHHHHHHHHH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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1971619; 10984043 [H]