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The map label for this gene is coaE [H]

Identifier: 124265699

GI number: 124265699

Start: 544541

End: 545164

Strand: Reverse

Name: coaE [H]

Synonym: Mpe_A0506

Alternate gene names: 124265699

Gene position: 545164-544541 (Counterclockwise)

Preceding gene: 124265700

Following gene: 124265698

Centisome position: 13.48

GC content: 69.87

Gene sequence:

>624_bases
ATGGGCAGCGAACGCATAAGCTTGCGCATCGGTCTCACCGGCGGCATCGGCAGTGGCAAGAGTACGGTGGCCGCGCTGCT
CGAAGGGCGCGGCGCGCTACTGGTGGATACCGATGCCATCGCACGCAGGCTTTCCGCGCCGGGTGGCGCCGCGCTTCCGG
CGCTGCGCGCGCAGTTCGGGCCGGACTGCATCGACCGCGCTGACGGAGGTCTCGACCGGGTCTGGATGAGGGCCCAGGCC
TTCGCCGACCCCGCCGTGCGTCTGCAGCTCGAGGCCATCCTGCACCCCCTGATCCGCGACGAGACGGAACAGTTCGCACG
CGCCGGCGTCGACGCAGCCTGCGTCGTGTTCGACGTACCCTTGCTGGTCGAGTCGGATCGCTGGCGTGATCGCGTCGATC
GCGTGCTGGTGGTCGATTGCCCCGAGGAAGTCCAGGTCGCGCGCGTGGCGCGACGGTCCGGCTGGACTCCCGACGAAGTG
CGGCGCGTGATGGCTCAGCAGGCCCCGCGGCCCCTCCGCCGAGCTGCGGCCGACGCCGTGATCGACAACCGGGGGGACTC
GCTCGATGCGCTACGGACGGTCATCGATGTCCTCTGGAAGCACTGGATGGCTGTAGACCGCTGA

Upstream 100 bases:

>100_bases
CTACGTGCCCTTCGGCCCCTTCCTGGCCGGTGCCGGACTGGTCGTCCTGTACGCAGGCGCCGAGCGCGTGATGGGCTGGC
TCGGCTGGGCCTGAGGCTCG

Downstream 100 bases:

>100_bases
GGCTGGGCATTCGCTCGGGGCGAACCCTGTGGAACAATCGGACGCGTTGCAGCGCGCAGGTGGCCCGCCTTGATCCTCTA
CGAGTACCCTTTGAACGAGA

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MGSERISLRIGLTGGIGSGKSTVAALLEGRGALLVDTDAIARRLSAPGGAALPALRAQFGPDCIDRADGGLDRVWMRAQA
FADPAVRLQLEAILHPLIRDETEQFARAGVDAACVVFDVPLLVESDRWRDRVDRVLVVDCPEEVQVARVARRSGWTPDEV
RRVMAQQAPRPLRRAAADAVIDNRGDSLDALRTVIDVLWKHWMAVDR

Sequences:

>Translated_207_residues
MGSERISLRIGLTGGIGSGKSTVAALLEGRGALLVDTDAIARRLSAPGGAALPALRAQFGPDCIDRADGGLDRVWMRAQA
FADPAVRLQLEAILHPLIRDETEQFARAGVDAACVVFDVPLLVESDRWRDRVDRVLVVDCPEEVQVARVARRSGWTPDEV
RRVMAQQAPRPLRRAAADAVIDNRGDSLDALRTVIDVLWKHWMAVDR
>Mature_206_residues
GSERISLRIGLTGGIGSGKSTVAALLEGRGALLVDTDAIARRLSAPGGAALPALRAQFGPDCIDRADGGLDRVWMRAQAF
ADPAVRLQLEAILHPLIRDETEQFARAGVDAACVVFDVPLLVESDRWRDRVDRVLVVDCPEEVQVARVARRSGWTPDEVR
RVMAQQAPRPLRRAAADAVIDNRGDSLDALRTVIDVLWKHWMAVDR

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=179, Percent_Identity=31.8435754189944, Blast_Score=89, Evalue=2e-18,
Organism=Homo sapiens, GI191252795, Length=179, Percent_Identity=31.8435754189944, Blast_Score=89, Evalue=2e-18,
Organism=Homo sapiens, GI110227607, Length=149, Percent_Identity=34.2281879194631, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI110227605, Length=151, Percent_Identity=33.7748344370861, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI110227603, Length=151, Percent_Identity=33.7748344370861, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI110227601, Length=151, Percent_Identity=33.7748344370861, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI205277394, Length=151, Percent_Identity=33.7748344370861, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1786292, Length=194, Percent_Identity=41.7525773195876, Blast_Score=122, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17554944, Length=191, Percent_Identity=35.6020942408377, Blast_Score=97, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24644728, Length=202, Percent_Identity=28.7128712871287, Blast_Score=86, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22605; Mature: 22474

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSERISLRIGLTGGIGSGKSTVAALLEGRGALLVDTDAIARRLSAPGGAALPALRAQFG
CCCCEEEEEEEEECCCCCCHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCHHHHHHHHCC
PDCIDRADGGLDRVWMRAQAFADPAVRLQLEAILHPLIRDETEQFARAGVDAACVVFDVP
CHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEEECH
LLVESDRWRDRVDRVLVVDCPEEVQVARVARRSGWTPDEVRRVMAQQAPRPLRRAAADAV
HHCCCCHHHHHHCEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHH
IDNRGDSLDALRTVIDVLWKHWMAVDR
HCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GSERISLRIGLTGGIGSGKSTVAALLEGRGALLVDTDAIARRLSAPGGAALPALRAQFG
CCCEEEEEEEEECCCCCCHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCHHHHHHHHCC
PDCIDRADGGLDRVWMRAQAFADPAVRLQLEAILHPLIRDETEQFARAGVDAACVVFDVP
CHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEEECH
LLVESDRWRDRVDRVLVVDCPEEVQVARVARRSGWTPDEVRRVMAQQAPRPLRRAAADAV
HHCCCCHHHHHHCEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHH
IDNRGDSLDALRTVIDVLWKHWMAVDR
HCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA