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The map label for this gene is exaA [H]

Identifier: 124265669

GI number: 124265669

Start: 515914

End: 517770

Strand: Reverse

Name: exaA [H]

Synonym: Mpe_A0476

Alternate gene names: 124265669

Gene position: 517770-515914 (Counterclockwise)

Preceding gene: 124265672

Following gene: 124265668

Centisome position: 12.8

GC content: 66.67

Gene sequence:

>1857_bases
ATGAGCAAGCATCCCGTCCGTCACGCCCTGTCCGTCGCAGCGGCGCTGGCCGTCCTGGGACTGTCCCAGGGTGCGCACGC
CGTCAAGAACGTCACCTGGGAAGACATCTCGAACGACGACCGCACGAGCACCGACGTCCTGAGCTACGGTCTGGGCCTGA
AGGCCCAGCGCTACAGCCCGCTGAAGCAGATATCGACCGCCAACGTGCAGAAGCTCGTCCCGGCATGGAGCCACTCCTTC
GGCGGCGAGAAGCAGCGCGGCCAGGAAGGCCAGGTGCTGGTGCATGACGGCGTGATCTACGCGACCAGTTCCTACTCTCG
CTTCACGGCGCTCGACGCGAAGACCGGCCGGCAGCTGTGGACCTACGAACACCGCCTGCCCGACGATATCCGTCCGTGCT
GCGACGTCGTCAACCGCGGCCCCGCCATCTACGGCGACAAGGTCTACTTCGGTACGCTCGACGCACGCGTCGTGGCGCTG
GACCGCGCCACCGGCAAGGTGGTGTGGAACGAGAAGTTCGGTGACCACAAGGTGGGCTACACGATGACCGGCGCGCCCTT
CATCGTGAAGGACAAGAAGTCCGGTCGCGTGCTGCTGATCCACGGCTCGTCGGGCGACGAGTTCGGCGTCGTCGGATGGC
TGTTCGCACGCGATCCCGACACCGGCGCCGAGGTCTGGGCTCGCCCGATGGTCGAGGGCCACATGGGCCGCCTGAACGGC
AAGGACAGCACGGTGACCGGCGATGCGAAGGCCCCCTCGTGGCCGCGTGACAAAGACGGCAAGCTGGTCGAGGCGTGGCA
CCAGGGCGGCGGCGCGCCGTGGCAGACCGCGTCGTTCGATGCCGAGAACAACACCATCGTGATCGGCACCGGCAACCCGG
CGCCGTGGAACACCTGGAAGCGCACGAAGGAAGGCGACGACCCGCGCAACTGGGACAGCCTGTTCACCTCGGGTCAGGCC
TACGTCGATGCGTCGACCGGCGAACTCAAGGGCTTCTTCCAGCACACGCCGAACGATGCCTGGGACTTCTCGGGCAACAA
CTCGATCGTGCTGTTCGAGTACAAGGACCCGAAGTCCGGCAAGCTGGTGAAGGCCGGCGCGCATGCCGACCGCAACGGCT
TTTTCTTCGTGACCGACCGCGAGAAGCTCGCGACCGGCGCCGGCTATCCGAACAAGCCGACCGCGCTGCTCGGTGCGTGG
CCGTTCGTCGACGGCATCACCTGGGCCAAGGGTTTCGACCTGAAGACCGGCAAGCCGATCGAGAACAACAACCGTCCGCC
GGCCCCCAAGCCCGGCGCCGACAAGGGCGAGTCGATCTTCGTGTCGCCGCCGTTCCTGGGCGGCACCAACTGGATGCCGA
TGAGCTACAGCCCGGACACCGGCCTGTTCTACATCCCGGCGAACCACTGGGCGATGGACTACTGGACCGAGCACCTGACC
TACAAGGCCGGCTCGGCCTACCTCGGCCAGGGCTTCCGCATCAAGCGGCTGTACGAGGACCACGTCGGCACGCTGCGGGC
AATCGACCCGGTGACCGGCAAGATCGCGTGGGAACACAAGGAGAAGCTGCCGCTGTGGGCCGGCACGATGACGACGGCCG
GCGGCCTGCTGTTCACCGGCACCTCCGACGGCTACGTGAAGGCCTTCGACAGCAAGACCGGCAAGGAACTGTGGAAGTTC
CAGACCGGCTCGGGCGTGGTCTCGGTCCCGGTGACCTGGGAGCAGGACGGCGAGCAGTACGTCGGCATCCAGTCGGGCTA
CGGCGGCGCCGTGCCCCTGTGGGGCGGTGACATGGCCGAGATGACCAAGAAGGTCACGCAGGGCGGCTCGATGTGGGTCT
TCAAGCTGCCCAAGTAG

Upstream 100 bases:

>100_bases
GGAGGATCTCCCGATCTCGCGCGGGCGATCTCCCGATACACCGTGGACCCCGCTTCCTAGACTCCGGCTCGCTCGTACAC
CACAACATGAGGAGATACCG

Downstream 100 bases:

>100_bases
GCAGACCCCGCTCGTGAGGGGCGGACCGGCGACCCCGCCGGCCCGCCCCTTCGTCCTCACTCCCCTTCGGCCGACGACAA
CATGACCTCCTCATCCCTGC

Product: quinoprotein alcohol dehydrogenase

Products: NA

Alternate protein names: QEDH [H]

Number of amino acids: Translated: 618; Mature: 617

Protein sequence:

>618_residues
MSKHPVRHALSVAAALAVLGLSQGAHAVKNVTWEDISNDDRTSTDVLSYGLGLKAQRYSPLKQISTANVQKLVPAWSHSF
GGEKQRGQEGQVLVHDGVIYATSSYSRFTALDAKTGRQLWTYEHRLPDDIRPCCDVVNRGPAIYGDKVYFGTLDARVVAL
DRATGKVVWNEKFGDHKVGYTMTGAPFIVKDKKSGRVLLIHGSSGDEFGVVGWLFARDPDTGAEVWARPMVEGHMGRLNG
KDSTVTGDAKAPSWPRDKDGKLVEAWHQGGGAPWQTASFDAENNTIVIGTGNPAPWNTWKRTKEGDDPRNWDSLFTSGQA
YVDASTGELKGFFQHTPNDAWDFSGNNSIVLFEYKDPKSGKLVKAGAHADRNGFFFVTDREKLATGAGYPNKPTALLGAW
PFVDGITWAKGFDLKTGKPIENNNRPPAPKPGADKGESIFVSPPFLGGTNWMPMSYSPDTGLFYIPANHWAMDYWTEHLT
YKAGSAYLGQGFRIKRLYEDHVGTLRAIDPVTGKIAWEHKEKLPLWAGTMTTAGGLLFTGTSDGYVKAFDSKTGKELWKF
QTGSGVVSVPVTWEQDGEQYVGIQSGYGGAVPLWGGDMAEMTKKVTQGGSMWVFKLPK

Sequences:

>Translated_618_residues
MSKHPVRHALSVAAALAVLGLSQGAHAVKNVTWEDISNDDRTSTDVLSYGLGLKAQRYSPLKQISTANVQKLVPAWSHSF
GGEKQRGQEGQVLVHDGVIYATSSYSRFTALDAKTGRQLWTYEHRLPDDIRPCCDVVNRGPAIYGDKVYFGTLDARVVAL
DRATGKVVWNEKFGDHKVGYTMTGAPFIVKDKKSGRVLLIHGSSGDEFGVVGWLFARDPDTGAEVWARPMVEGHMGRLNG
KDSTVTGDAKAPSWPRDKDGKLVEAWHQGGGAPWQTASFDAENNTIVIGTGNPAPWNTWKRTKEGDDPRNWDSLFTSGQA
YVDASTGELKGFFQHTPNDAWDFSGNNSIVLFEYKDPKSGKLVKAGAHADRNGFFFVTDREKLATGAGYPNKPTALLGAW
PFVDGITWAKGFDLKTGKPIENNNRPPAPKPGADKGESIFVSPPFLGGTNWMPMSYSPDTGLFYIPANHWAMDYWTEHLT
YKAGSAYLGQGFRIKRLYEDHVGTLRAIDPVTGKIAWEHKEKLPLWAGTMTTAGGLLFTGTSDGYVKAFDSKTGKELWKF
QTGSGVVSVPVTWEQDGEQYVGIQSGYGGAVPLWGGDMAEMTKKVTQGGSMWVFKLPK
>Mature_617_residues
SKHPVRHALSVAAALAVLGLSQGAHAVKNVTWEDISNDDRTSTDVLSYGLGLKAQRYSPLKQISTANVQKLVPAWSHSFG
GEKQRGQEGQVLVHDGVIYATSSYSRFTALDAKTGRQLWTYEHRLPDDIRPCCDVVNRGPAIYGDKVYFGTLDARVVALD
RATGKVVWNEKFGDHKVGYTMTGAPFIVKDKKSGRVLLIHGSSGDEFGVVGWLFARDPDTGAEVWARPMVEGHMGRLNGK
DSTVTGDAKAPSWPRDKDGKLVEAWHQGGGAPWQTASFDAENNTIVIGTGNPAPWNTWKRTKEGDDPRNWDSLFTSGQAY
VDASTGELKGFFQHTPNDAWDFSGNNSIVLFEYKDPKSGKLVKAGAHADRNGFFFVTDREKLATGAGYPNKPTALLGAWP
FVDGITWAKGFDLKTGKPIENNNRPPAPKPGADKGESIFVSPPFLGGTNWMPMSYSPDTGLFYIPANHWAMDYWTEHLTY
KAGSAYLGQGFRIKRLYEDHVGTLRAIDPVTGKIAWEHKEKLPLWAGTMTTAGGLLFTGTSDGYVKAFDSKTGKELWKFQ
TGSGVVSVPVTWEQDGEQYVGIQSGYGGAVPLWGGDMAEMTKKVTQGGSMWVFKLPK

Specific function: Catalyzes the oxidation of primary alcohols except for methanol that is a very poor substrate [H]

COG id: COG4993

COG function: function code G; Glucose dehydrogenase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial PQQ dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1786316, Length=382, Percent_Identity=23.2984293193717, Blast_Score=72, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019556
- InterPro:   IPR019551
- InterPro:   IPR018391
- InterPro:   IPR017512
- InterPro:   IPR002372
- InterPro:   IPR011047
- InterPro:   IPR001479 [H]

Pfam domain/function: PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]

EC number: =1.1.2.8 [H]

Molecular weight: Translated: 67610; Mature: 67479

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: PS00364 BACTERIAL_PQQ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKHPVRHALSVAAALAVLGLSQGAHAVKNVTWEDISNDDRTSTDVLSYGLGLKAQRYSP
CCCCHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHCCCCCCCCHHHHHHHCCCCCHHHCCH
LKQISTANVQKLVPAWSHSFGGEKQRGQEGQVLVHDGVIYATSSYSRFTALDAKTGRQLW
HHHHHHCCHHHHHHHHHCCCCCCHHCCCCCCEEEECCEEEEECCCCEEEEECCCCCCEEE
TYEHRLPDDIRPCCDVVNRGPAIYGDKVYFGTLDARVVALDRATGKVVWNEKFGDHKVGY
EECCCCCHHHHHHHHHHHCCCCEECCEEEEEECCEEEEEEECCCCEEEECCCCCCCCCCE
TMTGAPFIVKDKKSGRVLLIHGSSGDEFGVVGWLFARDPDTGAEVWARPMVEGHMGRLNG
EECCCEEEEEECCCCEEEEEECCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCC
KDSTVTGDAKAPSWPRDKDGKLVEAWHQGGGAPWQTASFDAENNTIVIGTGNPAPWNTWK
CCCEEECCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCEECCCCCEEEEECCCCCCCCHHC
RTKEGDDPRNWDSLFTSGQAYVDASTGELKGFFQHTPNDAWDFSGNNSIVLFEYKDPKSG
CCCCCCCCCCHHHHHCCCCEEEECCCCHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCC
KLVKAGAHADRNGFFFVTDREKLATGAGYPNKPTALLGAWPFVDGITWAKGFDLKTGKPI
CEEEECCCCCCCCEEEEECHHHHHCCCCCCCCCCEEEECCHHHCCCCCCCCCCCCCCCCC
ENNNRPPAPKPGADKGESIFVSPPFLGGTNWMPMSYSPDTGLFYIPANHWAMDYWTEHLT
CCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCEECCCCCEEEECCCCEEHHHHHHHHE
YKAGSAYLGQGFRIKRLYEDHVGTLRAIDPVTGKIAWEHKEKLPLWAGTMTTAGGLLFTG
EECCCHHHCCCEEEEEHHHHCCCEEEEECCCCCEEEECCCCCCCEEECCHHCCCCEEEEC
TSDGYVKAFDSKTGKELWKFQTGSGVVSVPVTWEQDGEQYVGIQSGYGGAVPLWGGDMAE
CCCCEEEEECCCCCHHHHEEECCCCEEEEEEEECCCCCEEEEEECCCCCEEECCCCCHHH
MTKKVTQGGSMWVFKLPK
HHHHHHCCCCEEEEECCC
>Mature Secondary Structure 
SKHPVRHALSVAAALAVLGLSQGAHAVKNVTWEDISNDDRTSTDVLSYGLGLKAQRYSP
CCCHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHCCCCCCCCHHHHHHHCCCCCHHHCCH
LKQISTANVQKLVPAWSHSFGGEKQRGQEGQVLVHDGVIYATSSYSRFTALDAKTGRQLW
HHHHHHCCHHHHHHHHHCCCCCCHHCCCCCCEEEECCEEEEECCCCEEEEECCCCCCEEE
TYEHRLPDDIRPCCDVVNRGPAIYGDKVYFGTLDARVVALDRATGKVVWNEKFGDHKVGY
EECCCCCHHHHHHHHHHHCCCCEECCEEEEEECCEEEEEEECCCCEEEECCCCCCCCCCE
TMTGAPFIVKDKKSGRVLLIHGSSGDEFGVVGWLFARDPDTGAEVWARPMVEGHMGRLNG
EECCCEEEEEECCCCEEEEEECCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCC
KDSTVTGDAKAPSWPRDKDGKLVEAWHQGGGAPWQTASFDAENNTIVIGTGNPAPWNTWK
CCCEEECCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCEECCCCCEEEEECCCCCCCCHHC
RTKEGDDPRNWDSLFTSGQAYVDASTGELKGFFQHTPNDAWDFSGNNSIVLFEYKDPKSG
CCCCCCCCCCHHHHHCCCCEEEECCCCHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCC
KLVKAGAHADRNGFFFVTDREKLATGAGYPNKPTALLGAWPFVDGITWAKGFDLKTGKPI
CEEEECCCCCCCCEEEEECHHHHHCCCCCCCCCCEEEECCHHHCCCCCCCCCCCCCCCCC
ENNNRPPAPKPGADKGESIFVSPPFLGGTNWMPMSYSPDTGLFYIPANHWAMDYWTEHLT
CCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCEECCCCCEEEECCCCEEHHHHHHHHE
YKAGSAYLGQGFRIKRLYEDHVGTLRAIDPVTGKIAWEHKEKLPLWAGTMTTAGGLLFTG
EECCCHHHCCCEEEEEHHHHCCCEEEEECCCCCEEEECCCCCCCEEECCHHCCCCEEEEC
TSDGYVKAFDSKTGKELWKFQTGSGVVSVPVTWEQDGEQYVGIQSGYGGAVPLWGGDMAE
CCCCEEEEECCCCCHHHHEEECCCCEEEEEEEECCCCCEEEEEECCCCCEEECCCCCHHH
MTKKVTQGGSMWVFKLPK
HHHHHHCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9826187; 10984043; 10075429; 10736230 [H]