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The map label for this gene is exaA [H]

Identifier: 124265556

GI number: 124265556

Start: 399003

End: 400721

Strand: Reverse

Name: exaA [H]

Synonym: Mpe_A0363

Alternate gene names: 124265556

Gene position: 400721-399003 (Counterclockwise)

Preceding gene: 124265557

Following gene: 124265555

Centisome position: 9.91

GC content: 66.96

Gene sequence:

>1719_bases
ATGAAACTCAAACTGACGCACATCGCGGCCTGCCTGGCCCTGGCGCCGCTGGCCGCGCTGGCCGACCTGCCCGCCTACGC
GCCCGTCACCGACGCGCGCCTCACCAACCCGGAGGCGAAGAACTGGCTGATGTACCGCGGCAACTACGCCGGCTGGGGCT
ACAGCCCGCTGGAGAAGATCAACGACAAGAACGTCTCCAAGCTCACGCTCGCGTGGTCCTACGTGACCGGCATGAGCGAG
GGGCACCAGTCGCCGCCGATCGTCAACAACGGCTACATGTACGTGACGACGCCGAACAACCAGGTGATCGCCTTCGAGGC
CAAGAGCGGCAAGGAGCTGTGGCGCTACAAGAAGCAGATCCCCGAGGAACTGCAGCAGTTGCACCCCACCAACCGCGGCG
TGGCGCTCTACAACGACAAGCTCTACCTCGCCACCACCGACGCGATGCTCGTGGCCCTGGACCCGGTGACCGGCAAGGAG
CTGTGGAAGTCCTCGGTCGGCGACTGGAAGGCGGGCTACTACTCGACGCTGGCGCCGCTGGTGGCCAACGGCAAGGTGGT
GACCGGCGTGTCGGGCGGCGAGTACGGAGTGCGCGGCTACGTGATCGCGCTCGACGCCGAGACCGGCAAGGAAGCGTGGC
GCACCTACACGATCCCCGCCCCCGGCGAGCCGGGCGGCGACACCTGGCCGGGCGAGACCTACAAGAAGGGCGGCGGCTCG
GTGTGGATCACCGGCACCTACGACCCCGAGACCAAGCTGTCCTACTGGGGCACCGGCAACGCCGCGCCGTGGATGGGCGA
CACGCGCGCGGGCGACAACCTCTACAGCACCTCGGTGATCGCGCTGGACATCGAGACCGGCAAGCTCAAGGGCTACCACC
AGTACCACTGGAACGACACCTGGGACTGGGACGAGGTCTCGGCGCCGCTGCTGGTCGACGTGGACCGCAACGGCAAGAAG
GTGAAGTCGCTGGTGCACGCGGGACGCAACGGCTACCTGTGGCAGCTCGAGCGCACCAGCGGCCCGATCAAGTTCGTGGA
CGCCTGGCCCTACGTGAAGCAGAACGTCTTCACCTCGATCGACCCGAAGACCGGCCGCCCGACCTACGACGAGAGCCGCC
GCCCGGCGACCGGCAAGACGGTGAACTTCTGCCCCTCGCTGTGGGGTGGCAAGGACTGGGTGCCCGAGGCCTACAGCCCG
AAGACCAAGATGTTCTACGTGCCGGCCAACAACAACCTCTGCTCGGAGCTTACCGGCGAGGCGGTCACCTACAAAAAGGG
TGACCTCTACATCGGCGTGGCGCTGGACAACATCCTCACCAACGTGCGGATGACCGAGGCCTCGAAGACCCACGTCGGCG
AGGTGCAGGCCTGGAACCTGGGCGACAAGAAGAAGGCCTGGACCCACACCTACCCCGAGATGAACTGGGGCCCGCTGCTG
GCCACCGGCGGCAACCTGGTTTTCGGCGGCGGCACCAACGACCGCCTGTTCCGCGCCTTCAACGCCAGCACCGGCAAGCT
GCTGTGGGAGTTCCCGGCCAGCTCGGGCGTGACCGGCGTGCCCTCGTCCTTCGAGGTCGACGGCGAGCAGTACATCGCCG
TGCAGTCGGGCTGGGGCGTCGACGCCGAGCGCATGCAGGGGGCCTTCAACGCGGTGCTCAAGAACAAGACCGTCGTGCCG
CAGGGCGGCACGGTGATGGTCTTCAAGCTGGGCAAGTAA

Upstream 100 bases:

>100_bases
CCTGACCCATTTCCCCACGACGGACCGGCTGCGGCAACGGCCGGCCCCGCCCTGATCGATTTCCCACCGCAAGAAAAACC
AACCCGAGGAGACACGACCC

Downstream 100 bases:

>100_bases
GCCCTCCCCCGTTCGATCCCGGACGGCAGCGGACCCCTCGGTCCGCTGCCGCTGGGGTGACTCGTCCCCAAAACAACTCA
CCCGGAGACAAGACATCATG

Product: putative alcohol dehydrogenase

Products: NA

Alternate protein names: QEDH [H]

Number of amino acids: Translated: 572; Mature: 572

Protein sequence:

>572_residues
MKLKLTHIAACLALAPLAALADLPAYAPVTDARLTNPEAKNWLMYRGNYAGWGYSPLEKINDKNVSKLTLAWSYVTGMSE
GHQSPPIVNNGYMYVTTPNNQVIAFEAKSGKELWRYKKQIPEELQQLHPTNRGVALYNDKLYLATTDAMLVALDPVTGKE
LWKSSVGDWKAGYYSTLAPLVANGKVVTGVSGGEYGVRGYVIALDAETGKEAWRTYTIPAPGEPGGDTWPGETYKKGGGS
VWITGTYDPETKLSYWGTGNAAPWMGDTRAGDNLYSTSVIALDIETGKLKGYHQYHWNDTWDWDEVSAPLLVDVDRNGKK
VKSLVHAGRNGYLWQLERTSGPIKFVDAWPYVKQNVFTSIDPKTGRPTYDESRRPATGKTVNFCPSLWGGKDWVPEAYSP
KTKMFYVPANNNLCSELTGEAVTYKKGDLYIGVALDNILTNVRMTEASKTHVGEVQAWNLGDKKKAWTHTYPEMNWGPLL
ATGGNLVFGGGTNDRLFRAFNASTGKLLWEFPASSGVTGVPSSFEVDGEQYIAVQSGWGVDAERMQGAFNAVLKNKTVVP
QGGTVMVFKLGK

Sequences:

>Translated_572_residues
MKLKLTHIAACLALAPLAALADLPAYAPVTDARLTNPEAKNWLMYRGNYAGWGYSPLEKINDKNVSKLTLAWSYVTGMSE
GHQSPPIVNNGYMYVTTPNNQVIAFEAKSGKELWRYKKQIPEELQQLHPTNRGVALYNDKLYLATTDAMLVALDPVTGKE
LWKSSVGDWKAGYYSTLAPLVANGKVVTGVSGGEYGVRGYVIALDAETGKEAWRTYTIPAPGEPGGDTWPGETYKKGGGS
VWITGTYDPETKLSYWGTGNAAPWMGDTRAGDNLYSTSVIALDIETGKLKGYHQYHWNDTWDWDEVSAPLLVDVDRNGKK
VKSLVHAGRNGYLWQLERTSGPIKFVDAWPYVKQNVFTSIDPKTGRPTYDESRRPATGKTVNFCPSLWGGKDWVPEAYSP
KTKMFYVPANNNLCSELTGEAVTYKKGDLYIGVALDNILTNVRMTEASKTHVGEVQAWNLGDKKKAWTHTYPEMNWGPLL
ATGGNLVFGGGTNDRLFRAFNASTGKLLWEFPASSGVTGVPSSFEVDGEQYIAVQSGWGVDAERMQGAFNAVLKNKTVVP
QGGTVMVFKLGK
>Mature_572_residues
MKLKLTHIAACLALAPLAALADLPAYAPVTDARLTNPEAKNWLMYRGNYAGWGYSPLEKINDKNVSKLTLAWSYVTGMSE
GHQSPPIVNNGYMYVTTPNNQVIAFEAKSGKELWRYKKQIPEELQQLHPTNRGVALYNDKLYLATTDAMLVALDPVTGKE
LWKSSVGDWKAGYYSTLAPLVANGKVVTGVSGGEYGVRGYVIALDAETGKEAWRTYTIPAPGEPGGDTWPGETYKKGGGS
VWITGTYDPETKLSYWGTGNAAPWMGDTRAGDNLYSTSVIALDIETGKLKGYHQYHWNDTWDWDEVSAPLLVDVDRNGKK
VKSLVHAGRNGYLWQLERTSGPIKFVDAWPYVKQNVFTSIDPKTGRPTYDESRRPATGKTVNFCPSLWGGKDWVPEAYSP
KTKMFYVPANNNLCSELTGEAVTYKKGDLYIGVALDNILTNVRMTEASKTHVGEVQAWNLGDKKKAWTHTYPEMNWGPLL
ATGGNLVFGGGTNDRLFRAFNASTGKLLWEFPASSGVTGVPSSFEVDGEQYIAVQSGWGVDAERMQGAFNAVLKNKTVVP
QGGTVMVFKLGK

Specific function: Catalyzes the oxidation of primary alcohols except for methanol that is a very poor substrate [H]

COG id: COG4993

COG function: function code G; Glucose dehydrogenase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial PQQ dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1786316, Length=356, Percent_Identity=27.247191011236, Blast_Score=116, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019556
- InterPro:   IPR019551
- InterPro:   IPR018391
- InterPro:   IPR017512
- InterPro:   IPR002372
- InterPro:   IPR011047
- InterPro:   IPR001479 [H]

Pfam domain/function: PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]

EC number: =1.1.2.8 [H]

Molecular weight: Translated: 62825; Mature: 62825

Theoretical pI: Translated: 8.54; Mature: 8.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKLTHIAACLALAPLAALADLPAYAPVTDARLTNPEAKNWLMYRGNYAGWGYSPLEKI
CEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHC
NDKNVSKLTLAWSYVTGMSEGHQSPPIVNNGYMYVTTPNNQVIAFEAKSGKELWRYKKQI
CCCCCEEEEEEEEEHHCCCCCCCCCCEEECCEEEEECCCCEEEEEECCCCHHHHHHHHHH
PEELQQLHPTNRGVALYNDKLYLATTDAMLVALDPVTGKELWKSSVGDWKAGYYSTLAPL
HHHHHHHCCCCCCEEEECCEEEEEECCEEEEEECCCCCHHHHHCCCCCCCCCHHHHHHHH
VANGKVVTGVSGGEYGVRGYVIALDAETGKEAWRTYTIPAPGEPGGDTWPGETYKKGGGS
HHCCEEEEECCCCCCCCEEEEEEEECCCCCCCCEEEECCCCCCCCCCCCCCCHHHCCCCE
VWITGTYDPETKLSYWGTGNAAPWMGDTRAGDNLYSTSVIALDIETGKLKGYHQYHWNDT
EEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEEEEEEECCCCCCEEEECCCCC
WDWDEVSAPLLVDVDRNGKKVKSLVHAGRNGYLWQLERTSGPIKFVDAWPYVKQNVFTSI
CCHHHCCCCEEEEECCCCHHHHHHHHCCCCCEEEEEECCCCCEEEEECCCHHHHCCEECC
DPKTGRPTYDESRRPATGKTVNFCPSLWGGKDWVPEAYSPKTKMFYVPANNNLCSELTGE
CCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHCCC
AVTYKKGDLYIGVALDNILTNVRMTEASKTHVGEVQAWNLGDKKKAWTHTYPEMNWGPLL
EEEEECCCEEEEEEHHHHHHCCEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCEE
ATGGNLVFGGGTNDRLFRAFNASTGKLLWEFPASSGVTGVPSSFEVDGEQYIAVQSGWGV
EECCCEEECCCCCCCEEEEECCCCCCEEEEECCCCCCCCCCCCEEECCCEEEEEECCCCC
DAERMQGAFNAVLKNKTVVPQGGTVMVFKLGK
CHHHHHHHHHHHHCCCEECCCCCEEEEEEECC
>Mature Secondary Structure
MKLKLTHIAACLALAPLAALADLPAYAPVTDARLTNPEAKNWLMYRGNYAGWGYSPLEKI
CEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHC
NDKNVSKLTLAWSYVTGMSEGHQSPPIVNNGYMYVTTPNNQVIAFEAKSGKELWRYKKQI
CCCCCEEEEEEEEEHHCCCCCCCCCCEEECCEEEEECCCCEEEEEECCCCHHHHHHHHHH
PEELQQLHPTNRGVALYNDKLYLATTDAMLVALDPVTGKELWKSSVGDWKAGYYSTLAPL
HHHHHHHCCCCCCEEEECCEEEEEECCEEEEEECCCCCHHHHHCCCCCCCCCHHHHHHHH
VANGKVVTGVSGGEYGVRGYVIALDAETGKEAWRTYTIPAPGEPGGDTWPGETYKKGGGS
HHCCEEEEECCCCCCCCEEEEEEEECCCCCCCCEEEECCCCCCCCCCCCCCCHHHCCCCE
VWITGTYDPETKLSYWGTGNAAPWMGDTRAGDNLYSTSVIALDIETGKLKGYHQYHWNDT
EEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEEEEEEECCCCCCEEEECCCCC
WDWDEVSAPLLVDVDRNGKKVKSLVHAGRNGYLWQLERTSGPIKFVDAWPYVKQNVFTSI
CCHHHCCCCEEEEECCCCHHHHHHHHCCCCCEEEEEECCCCCEEEEECCCHHHHCCEECC
DPKTGRPTYDESRRPATGKTVNFCPSLWGGKDWVPEAYSPKTKMFYVPANNNLCSELTGE
CCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHCCC
AVTYKKGDLYIGVALDNILTNVRMTEASKTHVGEVQAWNLGDKKKAWTHTYPEMNWGPLL
EEEEECCCEEEEEEHHHHHHCCEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCEE
ATGGNLVFGGGTNDRLFRAFNASTGKLLWEFPASSGVTGVPSSFEVDGEQYIAVQSGWGV
EECCCEEECCCCCCCEEEEECCCCCCEEEEECCCCCCCCCCCCEEECCCEEEEEECCCCC
DAERMQGAFNAVLKNKTVVPQGGTVMVFKLGK
CHHHHHHHHHHHHCCCEECCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9826187; 10984043; 10075429; 10736230 [H]