Click here to switch to the map view.

The map label for this gene is mreB [H]

Identifier: 124265276

GI number: 124265276

Start: 79154

End: 80197

Strand: Reverse

Name: mreB [H]

Synonym: Mpe_A0083

Alternate gene names: 124265276

Gene position: 80197-79154 (Counterclockwise)

Preceding gene: 124265280

Following gene: 124265275

Centisome position: 1.98

GC content: 67.05

Gene sequence:

>1044_bases
ATGTTCGCCTCCCTGCGACGCTATTTCTCCACCGACCTCGCGATCGACCTCGGCACCGCCAACACGCTGATCTACGTGCG
TGGCAAGGGCATCGTGCTCGACGAGCCTTCGGTCGTCGCGATCCGTCACGAAGGCGGCCCCAACGGCAAGAAGACCATCC
AGGCCGTCGGCGCCGAGGCCAAGGCCATGCTCGGCAAGGTGCCGGGCAACATCGAGGCCATCCGGCCGATGAAGGACGGC
GTGATCGCCGACTTCACCGTCACCGAGCAGATGCTCAAGCAGTTCATCAAGATGGTGCATCCGCGCTCGGTGCTCAAGCC
CAGCCCGCGCATCATCATCTGCGTGCCCTGCGGCTCGACGCAGGTGGAACGGCGTGCGATCCGCGAGTCGGCGCTCGGCG
CCGGTGCCTCCGAGGTCTACCTGATCGAGGAACCGATGGCCGCGGCCATCGGCGCCGGGCTGCCCGTCAGCGAGGCCACC
GGCTCGATGGTGGTCGACATCGGCGGCGGCACCACCGAGGTTGGCGTCATCTCGCTCGGCGGCATGGTCTACAAGGGCAG
CATCCGGGTCGGCGGCGACAAGTTCGACGAATCCATCATCAACTACATCCGCCGCAACTACGGCATGCTGATCGGAGACC
CCACCGCCGAGGCCATCAAGAAGCAGATCGGCTCGGCCTTCCCGGGCTCCGAAGTGCGCGAGATGGAGGTCAAGGGCCGC
AACCTCAGCGAAGGCGTGCCGCGCAGCTTCACGATCAGCAGCAACGAGATCCTCGAGGCGCTGACCGATCCGCTGAACAA
CATCGTCTCCAGCGTCAAGAACGCGCTGGAGCAGACGCCCCCCGAACTCGGCGCCGACATCTCCGAGCGCGGCATGATGC
TGACCGGCGGCGGCGCGCTGCTGCGCGACCTGGACCGTCTGCTGGCCGAGGAAACCGGCCTGCCGGTGCTGGTGGCCGAG
GACCCGCTGACCTGCGTGGTGCGCGGTTGCGGCATGGCGCTGGAGCGCATGGAGCGCCTGGGCAGCATCTTCACCTCCGA
GTAA

Upstream 100 bases:

>100_bases
GCCCAGATCGCTTCGAACACCGCCCCTCCCCATACCCAGGCGGCGCAGCCCTCGTAGCCCCCGGCTTCCTCGCTGCGGCG
CCCTGCAGAAACGCCAAGAC

Downstream 100 bases:

>100_bases
GTCGATGGCGCCGGCGCGAGCGCCCGAGCGCCGGGCCGCCCCAAGCCGGGCGCCATCCCCTCGGGGGATCGGCTGCGGCA
AGCCGCGGCCCAGGGGCCCG

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MFASLRRYFSTDLAIDLGTANTLIYVRGKGIVLDEPSVVAIRHEGGPNGKKTIQAVGAEAKAMLGKVPGNIEAIRPMKDG
VIADFTVTEQMLKQFIKMVHPRSVLKPSPRIIICVPCGSTQVERRAIRESALGAGASEVYLIEEPMAAAIGAGLPVSEAT
GSMVVDIGGGTTEVGVISLGGMVYKGSIRVGGDKFDESIINYIRRNYGMLIGDPTAEAIKKQIGSAFPGSEVREMEVKGR
NLSEGVPRSFTISSNEILEALTDPLNNIVSSVKNALEQTPPELGADISERGMMLTGGGALLRDLDRLLAEETGLPVLVAE
DPLTCVVRGCGMALERMERLGSIFTSE

Sequences:

>Translated_347_residues
MFASLRRYFSTDLAIDLGTANTLIYVRGKGIVLDEPSVVAIRHEGGPNGKKTIQAVGAEAKAMLGKVPGNIEAIRPMKDG
VIADFTVTEQMLKQFIKMVHPRSVLKPSPRIIICVPCGSTQVERRAIRESALGAGASEVYLIEEPMAAAIGAGLPVSEAT
GSMVVDIGGGTTEVGVISLGGMVYKGSIRVGGDKFDESIINYIRRNYGMLIGDPTAEAIKKQIGSAFPGSEVREMEVKGR
NLSEGVPRSFTISSNEILEALTDPLNNIVSSVKNALEQTPPELGADISERGMMLTGGGALLRDLDRLLAEETGLPVLVAE
DPLTCVVRGCGMALERMERLGSIFTSE
>Mature_347_residues
MFASLRRYFSTDLAIDLGTANTLIYVRGKGIVLDEPSVVAIRHEGGPNGKKTIQAVGAEAKAMLGKVPGNIEAIRPMKDG
VIADFTVTEQMLKQFIKMVHPRSVLKPSPRIIICVPCGSTQVERRAIRESALGAGASEVYLIEEPMAAAIGAGLPVSEAT
GSMVVDIGGGTTEVGVISLGGMVYKGSIRVGGDKFDESIINYIRRNYGMLIGDPTAEAIKKQIGSAFPGSEVREMEVKGR
NLSEGVPRSFTISSNEILEALTDPLNNIVSSVKNALEQTPPELGADISERGMMLTGGGALLRDLDRLLAEETGLPVLVAE
DPLTCVVRGCGMALERMERLGSIFTSE

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=349, Percent_Identity=72.2063037249284, Blast_Score=503, Evalue=1e-144,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 36875; Mature: 36875

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFASLRRYFSTDLAIDLGTANTLIYVRGKGIVLDEPSVVAIRHEGGPNGKKTIQAVGAEA
CCHHHHHHHCCCCEEEECCCCEEEEEECCEEEECCCCEEEEEECCCCCHHHHHHHHCHHH
KAMLGKVPGNIEAIRPMKDGVIADFTVTEQMLKQFIKMVHPRSVLKPSPRIIICVPCGST
HHHHHCCCCCCEEECCCCCCEEEEHHHHHHHHHHHHHHHCCHHHCCCCCCEEEEEECCCH
QVERRAIRESALGAGASEVYLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVGVISLG
HHHHHHHHHHHHCCCCCEEEEECCCHHHHHCCCCCCCCCCCCEEEEECCCCCEEEEEEEC
GMVYKGSIRVGGDKFDESIINYIRRNYGMLIGDPTAEAIKKQIGSAFPGSEVREMEVKGR
CEEEECEEEECCCHHHHHHHHHHHHHCCEEEECCHHHHHHHHHCCCCCCCCHHHHHHCCC
NLSEGVPRSFTISSNEILEALTDPLNNIVSSVKNALEQTPPELGADISERGMMLTGGGAL
CCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHCCEEEECCHHH
LRDLDRLLAEETGLPVLVAEDPLTCVVRGCGMALERMERLGSIFTSE
HHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFASLRRYFSTDLAIDLGTANTLIYVRGKGIVLDEPSVVAIRHEGGPNGKKTIQAVGAEA
CCHHHHHHHCCCCEEEECCCCEEEEEECCEEEECCCCEEEEEECCCCCHHHHHHHHCHHH
KAMLGKVPGNIEAIRPMKDGVIADFTVTEQMLKQFIKMVHPRSVLKPSPRIIICVPCGST
HHHHHCCCCCCEEECCCCCCEEEEHHHHHHHHHHHHHHHCCHHHCCCCCCEEEEEECCCH
QVERRAIRESALGAGASEVYLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVGVISLG
HHHHHHHHHHHHCCCCCEEEEECCCHHHHHCCCCCCCCCCCCEEEEECCCCCEEEEEEEC
GMVYKGSIRVGGDKFDESIINYIRRNYGMLIGDPTAEAIKKQIGSAFPGSEVREMEVKGR
CEEEECEEEECCCHHHHHHHHHHHHHCCEEEECCHHHHHHHHHCCCCCCCCHHHHHHCCC
NLSEGVPRSFTISSNEILEALTDPLNNIVSSVKNALEQTPPELGADISERGMMLTGGGAL
CCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHCCEEEECCHHH
LRDLDRLLAEETGLPVLVAEDPLTCVVRGCGMALERMERLGSIFTSE
HHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]