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The map label for this gene is moaC [H]

Identifier: 124265255

GI number: 124265255

Start: 57555

End: 58070

Strand: Direct

Name: moaC [H]

Synonym: Mpe_A0062

Alternate gene names: 124265255

Gene position: 57555-58070 (Clockwise)

Preceding gene: 124265252

Following gene: 124265266

Centisome position: 1.42

GC content: 68.8

Gene sequence:

>516_bases
ATGAGCGTCACCCCCAAGTCATCTTCACCGGCCAGCGGACTGACCCACTTCGACGCCCAGGGCCAGGCCCACATGGTCGA
CGTGTCCGCCAAGGCGGCGACGCACCGCGTGGCGGTGGCCGAGGGCTGGATCCGCATGCTGCCGGCCACGCTCCAGGTCA
TCTCGCAGGGCAGCGCGAAGAAGGGGGACGTGATCGGCATCGCGCGCATCGCGGCCATCCAGGCGGCCAAGCGCACGGCC
GAATTGATCCCCCTGTGCCACCCGCTGCCGCTGACGCGCGTGGCCGCCGAGTTCGAGATCGATGAGACCGCCACTCGCAT
TGCCTGCCGCGTGACGGCCGAGACACTGGGGCCCACCGGCGTGGAGATGGAGGCATTGACGGCCGTGCAGATCGGCCTGC
TGACCATCTACGACATGTGCAAGGCGATCGACCGGGGCATGGTGATCGAGGGCGTGCGGCTGCTCGAGAAGCATGGCGGC
AAGTCGGGTTCGTTCGTGGCCGACACCGCGGGCTGA

Upstream 100 bases:

>100_bases
GTCGGCGGCGGGTCTCGGGTGTGACCTTCGCGCAGCAAGGCAGTTCAGCAAGGCGTGCGTCTATGATGCCGCAGCCTTGT
TTCCCATTGTTGCCGCAGCC

Downstream 100 bases:

>100_bases
CGGCGCCCCCCGGCTCAAGGCTCCAGGTCGCGCCAGGTCAGCGCTACCGGATCGGTTCGGCACTGGAAGGGCGGCACCGG
GTTGTCGGCCGTGCAATTCT

Product: GTP cyclohydrolase subunit MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MSVTPKSSSPASGLTHFDAQGQAHMVDVSAKAATHRVAVAEGWIRMLPATLQVISQGSAKKGDVIGIARIAAIQAAKRTA
ELIPLCHPLPLTRVAAEFEIDETATRIACRVTAETLGPTGVEMEALTAVQIGLLTIYDMCKAIDRGMVIEGVRLLEKHGG
KSGSFVADTAG

Sequences:

>Translated_171_residues
MSVTPKSSSPASGLTHFDAQGQAHMVDVSAKAATHRVAVAEGWIRMLPATLQVISQGSAKKGDVIGIARIAAIQAAKRTA
ELIPLCHPLPLTRVAAEFEIDETATRIACRVTAETLGPTGVEMEALTAVQIGLLTIYDMCKAIDRGMVIEGVRLLEKHGG
KSGSFVADTAG
>Mature_170_residues
SVTPKSSSPASGLTHFDAQGQAHMVDVSAKAATHRVAVAEGWIRMLPATLQVISQGSAKKGDVIGIARIAAIQAAKRTAE
LIPLCHPLPLTRVAAEFEIDETATRIACRVTAETLGPTGVEMEALTAVQIGLLTIYDMCKAIDRGMVIEGVRLLEKHGGK
SGSFVADTAG

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=154, Percent_Identity=55.8441558441558, Blast_Score=162, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI32566331, Length=161, Percent_Identity=47.8260869565217, Blast_Score=140, Evalue=2e-34,
Organism=Drosophila melanogaster, GI28574490, Length=150, Percent_Identity=49.3333333333333, Blast_Score=138, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28574492, Length=137, Percent_Identity=48.1751824817518, Blast_Score=124, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 17888; Mature: 17757

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVTPKSSSPASGLTHFDAQGQAHMVDVSAKAATHRVAVAEGWIRMLPATLQVISQGSAK
CCCCCCCCCCCCCCEEECCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KGDVIGIARIAAIQAAKRTAELIPLCHPLPLTRVAAEFEIDETATRIACRVTAETLGPTG
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCHHHHHEEEEEEHHHCCCCC
VEMEALTAVQIGLLTIYDMCKAIDRGMVIEGVRLLEKHGGKSGSFVADTAG
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEECCCC
>Mature Secondary Structure 
SVTPKSSSPASGLTHFDAQGQAHMVDVSAKAATHRVAVAEGWIRMLPATLQVISQGSAK
CCCCCCCCCCCCCEEECCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KGDVIGIARIAAIQAAKRTAELIPLCHPLPLTRVAAEFEIDETATRIACRVTAETLGPTG
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCHHHHHEEEEEEHHHCCCCC
VEMEALTAVQIGLLTIYDMCKAIDRGMVIEGVRLLEKHGGKSGSFVADTAG
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA