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The map label for this gene is psmB1

Identifier: 124028410

GI number: 124028410

Start: 1573956

End: 1574570

Strand: Direct

Name: psmB1

Synonym: Hbut_1564

Alternate gene names: 124028410

Gene position: 1573956-1574570 (Clockwise)

Preceding gene: 124028407

Following gene: 124028411

Centisome position: 94.41

GC content: 49.76

Gene sequence:

>615_bases
ATGAGCTATGAGTATGGTACGGGTGCTACTGCAGTAGGAATACGCGGCGCCGGCTACGTCGTACTAGCTGCCGAGAAGAG
AGTTAGCTATGGAGGCTTCATAATCAGCAAGACGGCACGAAAGGTCTACAAGATAACAGATTACCTAGGCCTTGCGCTCG
CTGGCCTTTTCGCCGACCTACAAGCAATAAGTAAGATACTACGCGCTGAAATAGAATACTACAACATCGTGACAGGGCGT
AGGATATCGGTAAGAGCTGTTGCAAGACTACTAGCAACAATACTCTACTCGTACAAGTACTATCCATTCCTCTCTGAGAC
GCTAGTTGGCGGCCTTGAAGCTGATGGTACAGCAAAGCTCTACGTAATGGACCCCTTAGGCTCGCTTATTGAGGACGACT
ACGCAGCCATAGGCTCCGGAGCACCCATAGCTATAGGTATACTCGAAAACGGATATAGTAAGGACATGAGTGTTGATGAT
GCCAAGAAGCTTGCAATAGCAGCTGTACGAGCAGCGATAGAGAGGGACGCCATGTCTGGCGACGGGATAGACCTGCTAGT
GATACGCAGGGAGGAGGACAGCATAAAGGCCGAAGAGGAGTCCATAACAATCTAG

Upstream 100 bases:

>100_bases
AGAGTTGGAGGATGGAAGAAGGAGGCCCTACCCGCAACACGCATAGTTATAGATAATAGTTATAACCCATACCCTAGCAC
AGACTGATATGGTGGCAGTG

Downstream 100 bases:

>100_bases
ACAGCCTCTGGGGCGGCTGTTTTTGACATACAGCTCGGTTGCAAAGCTCATAGAGCTACAGAAGAGGCTCTCCAGGAGGA
TAGTCTCAAGCCTAAAACCC

Product: proteasome beta subunit

Products: NA

Alternate protein names: 20S proteasome beta subunit 1; Proteasome core protein PsmB 1

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MSYEYGTGATAVGIRGAGYVVLAAEKRVSYGGFIISKTARKVYKITDYLGLALAGLFADLQAISKILRAEIEYYNIVTGR
RISVRAVARLLATILYSYKYYPFLSETLVGGLEADGTAKLYVMDPLGSLIEDDYAAIGSGAPIAIGILENGYSKDMSVDD
AKKLAIAAVRAAIERDAMSGDGIDLLVIRREEDSIKAEEESITI

Sequences:

>Translated_204_residues
MSYEYGTGATAVGIRGAGYVVLAAEKRVSYGGFIISKTARKVYKITDYLGLALAGLFADLQAISKILRAEIEYYNIVTGR
RISVRAVARLLATILYSYKYYPFLSETLVGGLEADGTAKLYVMDPLGSLIEDDYAAIGSGAPIAIGILENGYSKDMSVDD
AKKLAIAAVRAAIERDAMSGDGIDLLVIRREEDSIKAEEESITI
>Mature_203_residues
SYEYGTGATAVGIRGAGYVVLAAEKRVSYGGFIISKTARKVYKITDYLGLALAGLFADLQAISKILRAEIEYYNIVTGRR
ISVRAVARLLATILYSYKYYPFLSETLVGGLEADGTAKLYVMDPLGSLIEDDYAAIGSGAPIAIGILENGYSKDMSVDDA
KKLAIAAVRAAIERDAMSGDGIDLLVIRREEDSIKAEEESITI

Specific function: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation

COG id: COG0638

COG function: function code O; 20S proteasome, alpha and beta subunits

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family

Homologues:

Organism=Homo sapiens, GI4506193, Length=194, Percent_Identity=28.8659793814433, Blast_Score=104, Evalue=7e-23,
Organism=Homo sapiens, GI4506201, Length=195, Percent_Identity=32.8205128205128, Blast_Score=97, Evalue=7e-21,
Organism=Homo sapiens, GI68303563, Length=189, Percent_Identity=31.7460317460317, Blast_Score=93, Evalue=1e-19,
Organism=Homo sapiens, GI22538465, Length=195, Percent_Identity=26.1538461538462, Blast_Score=88, Evalue=5e-18,
Organism=Homo sapiens, GI153791216, Length=182, Percent_Identity=31.3186813186813, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI68303561, Length=195, Percent_Identity=30.7692307692308, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI73747875, Length=200, Percent_Identity=27.5, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI4506203, Length=186, Percent_Identity=30.1075268817204, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI4758970, Length=200, Percent_Identity=27.5, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI4506189, Length=191, Percent_Identity=31.9371727748691, Blast_Score=83, Evalue=1e-16,
Organism=Homo sapiens, GI4506191, Length=184, Percent_Identity=29.3478260869565, Blast_Score=83, Evalue=1e-16,
Organism=Homo sapiens, GI195539356, Length=150, Percent_Identity=32.6666666666667, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI23110942, Length=191, Percent_Identity=25.6544502617801, Blast_Score=74, Evalue=7e-14,
Organism=Homo sapiens, GI23110925, Length=187, Percent_Identity=25.1336898395722, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17508495, Length=190, Percent_Identity=32.1052631578947, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17535357, Length=193, Percent_Identity=25.9067357512953, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17508491, Length=193, Percent_Identity=29.0155440414508, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17541700, Length=188, Percent_Identity=27.6595744680851, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17554384, Length=191, Percent_Identity=24.6073298429319, Blast_Score=80, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17508499, Length=175, Percent_Identity=30.2857142857143, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17508493, Length=192, Percent_Identity=27.6041666666667, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6325360, Length=178, Percent_Identity=30.8988764044944, Blast_Score=95, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6324731, Length=190, Percent_Identity=29.4736842105263, Blast_Score=89, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6319430, Length=210, Percent_Identity=26.1904761904762, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6321574, Length=185, Percent_Identity=27.5675675675676, Blast_Score=72, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6324535, Length=201, Percent_Identity=24.8756218905473, Blast_Score=63, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323547, Length=193, Percent_Identity=27.4611398963731, Blast_Score=62, Evalue=6e-11,
Organism=Drosophila melanogaster, GI28573221, Length=186, Percent_Identity=32.258064516129, Blast_Score=98, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24639979, Length=182, Percent_Identity=31.8681318681319, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI20130281, Length=191, Percent_Identity=31.9371727748691, Blast_Score=94, Evalue=5e-20,
Organism=Drosophila melanogaster, GI17737605, Length=196, Percent_Identity=27.0408163265306, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24654391, Length=197, Percent_Identity=25.8883248730964, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24654389, Length=197, Percent_Identity=25.8883248730964, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21355573, Length=191, Percent_Identity=29.8429319371728, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24652553, Length=191, Percent_Identity=29.8429319371728, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24664391, Length=172, Percent_Identity=29.6511627906977, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21356137, Length=188, Percent_Identity=32.4468085106383, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24584895, Length=177, Percent_Identity=29.9435028248588, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21355629, Length=188, Percent_Identity=25, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17933602, Length=168, Percent_Identity=29.7619047619048, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24653999, Length=186, Percent_Identity=27.4193548387097, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24581176, Length=184, Percent_Identity=24.4565217391304, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PSB1_HYPBU (A2BN24)

Other databases:

- EMBL:   CP000493
- RefSeq:   YP_001013730.1
- ProteinModelPortal:   A2BN24
- SMR:   A2BN24
- MEROPS:   T01.002
- GeneID:   4782615
- GenomeReviews:   CP000493_GR
- KEGG:   hbu:Hbut_1564
- eggNOG:   arNOG09775
- HOGENOM:   HBG499923
- OMA:   EKRVSYG
- PhylomeDB:   A2BN24
- GO:   GO:0005737
- HAMAP:   MF_02113_A
- InterPro:   IPR019983
- InterPro:   IPR000243
- InterPro:   IPR016050
- InterPro:   IPR001353
- PRINTS:   PR00141
- TIGRFAMs:   TIGR03634

Pfam domain/function: PF00227 Proteasome

EC number: =3.4.25.1

Molecular weight: Translated: 21970; Mature: 21838

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00854 PROTEASOME_B_1; PS51476 PROTEASOME_B_2

Important sites: ACT_SITE 10-10

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYEYGTGATAVGIRGAGYVVLAAEKRVSYGGFIISKTARKVYKITDYLGLALAGLFADL
CCCCCCCCCEEEEECCCCEEEEEECCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHH
QAISKILRAEIEYYNIVTGRRISVRAVARLLATILYSYKYYPFLSETLVGGLEADGTAKL
HHHHHHHHHHHHHEEEECCCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCEEE
YVMDPLGSLIEDDYAAIGSGAPIAIGILENGYSKDMSVDDAKKLAIAAVRAAIERDAMSG
EEECCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
DGIDLLVIRREEDSIKAEEESITI
CCEEEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
SYEYGTGATAVGIRGAGYVVLAAEKRVSYGGFIISKTARKVYKITDYLGLALAGLFADL
CCCCCCCCEEEEECCCCEEEEEECCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHH
QAISKILRAEIEYYNIVTGRRISVRAVARLLATILYSYKYYPFLSETLVGGLEADGTAKL
HHHHHHHHHHHHHEEEECCCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCEEE
YVMDPLGSLIEDDYAAIGSGAPIAIGILENGYSKDMSVDDAKKLAIAAVRAAIERDAMSG
EEECCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
DGIDLLVIRREEDSIKAEEESITI
CCEEEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA